The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
MAP kinases and cell migration
Open accessAbstract
Recent studies have demonstrated that mitogen-activated protein kinases (MAPKs), including Jun N-terminus kinase (JNK), p38 and Erk, play crucial roles in cell migration. JNK, for example, regulates cell migration by phosphorylating paxillin, DCX, Jun and microtubule-associated proteins. Studies of p38 show that this MAPK modulates migration by phosphorylating MAPK-activated protein kinase 2/3 (MAPKAP 2/3), which appears to be important for directionality of migration. Erk governs cell movement by phosphorylating myosin light chain kinase (MLCK), calpain or FAK. Thus, the different kinases in the MAPK family all seem able to regulate cell migration but by distinct mechanisms.
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Cites
Aguirre, V., Uchida, T., Yenush, L., Davis, R., & White, M. F. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.12.9047 · Cited by 1,487
Regulation of Cell Migration by the Calcium-dependent Protease Calpain
Huttenlocher, A., Palecek, S. P., Lu, Q., Zhang, W., Mellgren, R. L., Lauffenburger, D. A., Ginsberg, M. H., & Horwitz, A. F. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.52.32719 · Cited by 390 · cited 2×
“Calpain Calpains are a family of Ca2+-activated proteolytic enzymes that are involved in cell migration (Dourdin et al., 2001; Huttenlocher et al., 1997).”
Backgroundp38 and ERK1/2 Coordinate Cellular Migration and Proliferation in Epithelial Wound Healing
Sharma, G.-D., He, J., & Bazan, H. E. P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302650200 · Cited by 337
Glading, A., Bodnar, R. J., Reynolds, I. J., Shiraha, H., Satish, L., Potter, D. A., Blair, H. C., & Wells, A. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.6.2499-2512.2004 · Cited by 271
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Pathological roles of MAPK signaling pathways in human diseases
Kim, E. K., & Choi, E.-J. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.12.009 · Cited by 2,472
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Ullah, R., Yin, Q., Snell, A. H., & Wan, L. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.05.010 · Cited by 553
Targeting dual-specificity phosphatases: Manipulating MAP kinase signalling and immune responses
Jeffrey, K. L., Camps, M., Rommel, C., & Mackay, C. R. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2289 · Cited by 533
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Rockey, D. C., Weymouth, N., & Shi, Z. (2013) · PLoS ONE · doi:10.1371/journal.pone.0077166 · Cited by 188
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Nguyen-Jackson, H., Panopoulos, A. D., Zhang, H., Li, H. S., & Watowich, S. S. (2010) · Blood · doi:10.1182/blood-2009-08-240317 · Cited by 151
Clement, D. L., Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, S. F., & Christensen, S. T. (2012) · Journal of Cell Science · doi:10.1242/jcs.116426 · Cited by 94
Protein kinase inhibitors can control the progression of endometriosis in vitro and in vivo
Ngô, C., Nicco, C., Leconte, M., Chéreau, C., Arkwright, S., Vacher‐Lavenu, M., Weill, B., Chapron, C., & Batteux, F. (2010) · The Journal of Pathology · doi:10.1002/path.2756 · Cited by 78
JNK signaling is converted from anti- to pro-tumor pathway by Ras-mediated switch of Warts activity
Enomoto, M., Kizawa, D., Ohsawa, S., & Igaki, T. (2015) · Developmental Biology · doi:10.1016/j.ydbio.2015.05.001 · Cited by 74
MiR-139-5p: promising biomarker for cancer
Zhang, H.-D., Jiang, L.-H., Sun, D.-W., Li, J., & Tang, J.-H. (2015) · Tumor Biology · doi:10.1007/s13277-015-3199-3 · Cited by 69
Choi, Y.-H., Yang, D., Kulkarni, A., Moh, S., & Kim, K. (2015) · Marine Drugs · doi:10.3390/md13127056 · Cited by 61
Involvement of P38MAPK in human corneal endothelial cell migration induced by TGF-β2
Joko, T., Shiraishi, A., Akune, Y., Tokumaru, S., Kobayashi, T., Miyata, K., & Ohashi, Y. (2013) · Experimental Eye Research · doi:10.1016/j.exer.2012.11.018 · Cited by 49
Li, J., Dai, G., Cheng, Y.-B., Qi, X., & Geng, M.-Y. (2011) · Glycobiology · doi:10.1093/glycob/cwr020 · Cited by 37
Gnanaprakasam, J. N. R., Estrada-Muñiz, E., & Vega, L. (2015) · International Immunopharmacology · doi:10.1016/j.intimp.2015.08.038 · Cited by 37
Djuzenova, C. S., Fiedler, V., Memmel, S., Katzer, A., Hartmann, S., Krohne, G., Zimmermann, H., Scholz, C.-J., Polat, B., Flentje, M., et al. (2015) · Experimental Cell Research · doi:10.1016/j.yexcr.2014.08.013 · Cited by 34
JNK MAPK Signaling Contributes in vivo to Injury-Induced Corneal Epithelial Migration
Okada, Y., Saika, S., Shirai, K., Yamanaka, O., Kitano, A., Wang, Z., Yang, H., & Reinach, P. (2009) · Ophthalmic Research · doi:10.1159/000232401 · Cited by 20
Carmo, J., Cavalcante-Araújo, P., Silva, J., Ferro, J., Correia, A. C., Lagente, V., & Barreto, E. (2020) · Molecules · doi:10.3390/molecules25214982 · Cited by 18
Metadata
- Authors
- Huang, C., Jacobson, K., & Schaller, M. D.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 2004-09-15
- Volume
- 117
- Issue
- 20
- Pages
- 4619-4628
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W2040196938
- Cited by
- 1,074
- References
- 4
- FWCI
- 15.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
