The DOI matches its Crossref record; 93 of the 93 references it cites were found in a registry or an index.
HSF1 at a glance
Abstract
Heat shock factor 1 (HSF1) is an evolutionarily highly conserved transcription factor that coordinates stress-induced transcription and directs versatile physiological processes in eukaryotes. The central position of HSF1 in cellular homeostasis has been well demonstrated, mainly through its strong effect in transactivating genes that encode heat shock proteins (HSPs). However, recent genome-wide studies have revealed that HSF1 is capable of reprogramming transcription more extensively than previously assumed; it is also involved in a multitude of processes in stressed and non-stressed cells. Consequently, the importance of HSF1 in fundamental physiological events, including metabolism, gametogenesis and aging, has become apparent and its significance in pathologies, such as cancer progression, is now evident. In this Cell Science at a Glance article, we highlight recent advances in the HSF1 field, discuss the organismal control over HSF1, and present the processes that are mediated by HSF1 in the context of cell type, cell-cycle phase, physiological condition and received stimuli.
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Cites
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“…that stress responses are under neuronal control, communicated between tissues and integrated to the metabolic processes of the animal (Baumeister et al., 2006; Durieux et al., 2011; Garcia et al., 2007; van Oosten-Hawle et al., 2013; Prahlad et al., 2008; reviewed in Gidalevitz et al., 2011).”
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Cited by
Transcriptional response to stress is pre-wired by promoter and enhancer architecture
Vihervaara, A., Mahat, D. B., Guertin, M. J., Chu, T., Danko, C. G., Lis, J. T., & Sistonen, L. (2017) · Nature Communications · doi:10.1038/s41467-017-00151-0 · Cited by 164
Self-citationAlzheimer’s as a Systems-Level Disease Involving the Interplay of Multiple Cellular Networks
Castrillo, J. I., & Oliver, S. G. (2016) · Methods in Molecular Biology · doi:10.1007/978-1-4939-2627-5_1 · Cited by 44
Bianchi, M., Crinelli, R., Arbore, V., & Magnani, M. (2018) · FEBS Open Bio · doi:10.1002/2211-5463.12484 · Cited by 40
Metadata
- Authors
- Vihervaara, A., & Sistonen, L.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 2014-01-15
- Volume
- 127
- Issue
- 2
- Pages
- 261-266
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W2326884456
- Cited by
- 304
- References
- 93
- FWCI
- 11.07
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
