The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Plasticity of Chemotaxis Revealed by Paired Presentation of A Chemoattractant and Starvation in the Nematode Caenorhabditis Elegans
Abstract
While the basic functioning of the nervous system of Caenorhabditis elegans has been extensively studied, its behavioural plasticities have not been fully explored because of the limited availability of assay systems. We report here a simple form of chemotaxis plasticity in this organism: when worms are starved on plates that contain NaCl, their chemotaxis towards NaCl falls dramatically. This conditioning requires both the presence of NaCl and the absence of a bacterial food source, indicating that it is not merely adaptation or habituation, but that it is likely to be a form of associative learning. While chemotaxis towards volatile chemoattractants does not change significantly after conditioning with NaCl, chemotaxis towards other water-soluble attractants does decrease. This suggests that an altered response of a cell or a group of cells specifically involved in chemotaxis towards water-soluble chemoattractants is responsible for the behavioural alteration. The decrease in chemotaxis occurred slowly over 3–4 h of conditioning and returned quickly to the original level when either of the conditioning stimuli, NaCl or starvation, was removed. The application of serotonin partially blocked this reduction in chemotaxis, consistent with the proposed function of this neurotransmitter in food signalling. Using this assay, we have isolated three mutants with reduced plasticity. This assay system expands the opportunities for studying the molecular and cellular mechanisms of behavioural plasticity in C. elegans.
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Cited by
Dietary choice behavior in Caenorhabditis elegans
Shtonda, B. B., & Avery, L. (2006) · Journal of Experimental Biology · doi:10.1242/jeb.01955 · Cited by 431
An elegant mind: Learning and memory in Caenorhabditis elegans
Ardiel, E. L., & Rankin, C. H. (2010) · Learning & Memory · doi:10.1101/lm.960510 · Cited by 323
Parallel Use of Two Behavioral Mechanisms for Chemotaxis in Caenorhabditis elegans
Iino, Y., & Yoshida, K. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3633-08.2009 · Cited by 264
Self-citationAntagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans
Hukema, R. K., Rademakers, S., Dekkers, M. P., Burghoorn, J., & Jansen, G. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7600940 · Cited by 111
Chen, N., Li, J., Li, D., Yang, Y., & He, D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113453 · Cited by 105
Metadata
- Authors
- Saeki, S., Yamamoto, M., & Iino, Y.
- Venue
- Journal of Experimental Biology
- Publisher
- The Company of Biologists
- Published
- 2001-05-15
- Volume
- 204
- Issue
- 10
- Pages
- 1757-1764
- ISSN
- 0022-0949 (ISSN-L)
- 1477-9145
- OpenAlex
- W2188777107
- Cited by
- 269
- References
- 1
- FWCI
- 0.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Saeki, S., Yamamoto, M., & Iino, Y. (2001). Plasticity of Chemotaxis Revealed by Paired Presentation of A Chemoattractant and Starvation in the Nematode Caenorhabditis Elegans. Journal of Experimental Biology. https://doi.org/10.1242/jeb.204.10.1757
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