CoChat
Sign Up
Cited by 928Traumatic Brain Injury ResearchSports injuries and preventionSport Psychology and Performance

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Recurrent Concussion and Risk of Depression in Retired Professional Football Players

GUSKIEWICZ, KEVIN M., MARSHALL, STEPHEN W., BAILES, JULIAN, MCCREA, MICHAEL, HARDING, HERNDON P., MATTHEWS, AMY, MIHALIK, JOHNA REGISTER, CANTU, ROBERT C.·2007·Medicine & Science in Sports & Exercise
DOI 10.1249/mss.0b013e3180383da5
Open this paper in CoChat — free account

Abstract

PURPOSE: The purpose of our study was to investigate the association between prior head injury and the likelihood of being diagnosed with clinical depression among retired professional football players with prior head injury exposure. METHODS: A general health questionnaire, including information about prior injuries, the SF-36 (Short Form 36), and other markers for depression, was completed by 2552 retired professional football players with an average age of 53.8 (+/-13.4) yr and an average professional football-playing career of 6.6 (+/-3.6) yr. A second questionnaire focusing on mild cognitive impairment (MCI)-related issues was completed by a subset of 758 retired professional football players (50 yr and older). RESULTS: Two hundred sixty-nine (11.1%) of all respondents reported having prior or current diagnosis of clinical depression. There was an association between recurrent concussion and diagnosis of lifetime depression (chi2=71.21, df=2, P<0.005), suggesting that the prevalence increases with increasing concussion history. Compared with retired players with no history of concussion, retired players reporting three or more previous concussions (24.4%) were three times more likely to be diagnosed with depression; those with a history of one or two previous concussions (36.3%) were 1.5 times more likely to be diagnosed with depression. The analyses controlled for age, number of years since retirement, number of years played, physical component score on the SF-36, and diagnosed comorbidities such as osteoarthritis, coronary heart disease, stroke, cancer, and diabetes. CONCLUSION: Our findings suggest a possible link between recurrent sport-related concussion and increased risk of clinical depression. The findings emphasize the importance of understanding potential neurological consequences of recurrent concussion.

Overview

Integrity signals

Registry

Crossref · 10.1249/mss.0b013e3180383da5

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 39 references

Research works printed but not linked: 2

  1. Heilbronner, 1993, Factors associated with postconcussion syndrome: neurological, psychological, or legal?, Trial Diplomacy J, 16, 161
  2. Iverson, 1998, Complicated versus uncomplicated mild head injury., J Int Neuropsychol Soc, 4, 75

Cited by

Sorted by citations

Items 501–600 of 926

Related

See all

Metadata

Authors
GUSKIEWICZ, K. M., MARSHALL, S. W., BAILES, J., MCCREA, M., HARDING, H. P., MATTHEWS, A., MIHALIK, J. R., & CANTU, R. C.
Affiliations
  • University of North Carolina at Chapel Hill (US)
  • West Virginia University (US)
  • Medical College of Wisconsin (US)
  • Florida State University (US)
  • Brigham and Women's Hospital (US)
ORCID
Venue
Medicine & Science in Sports & Exercise
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2007-06
Volume
39
Issue
6
Pages
903-909
ISSN
0195-9131 (ISSN-L)
DOI
10.1249/mss.0b013e3180383da5
OpenAlex
W2123674272
Cited by
928
References
39
Citations by year
2026: 17 · 2025: 27 · 2024: 28 · 2023: 33 · 2022: 36 · 2021: 64 · 2020: 52 · 2019: 81 · 2018: 56 · 2017: 81 · 2016: 67 · 2015: 83 · 2014: 71 · 2013: 65 · 2012: 42
FWCI
17.65
Type
journal article
Language
en
Open access
closed
Locations
  • Medicine & Science in Sports & Exercise (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports injuries and prevention
  • Social Sciences › Psychology › Developmental and Educational Psychology › Sport Psychology and Performance
Keywords
recurrent concussion, sports-related concussion, major depressive disorder, traumatic brain injury, mild cognitive impairment, depression risk
MeSH terms
Adult, Aged, Brain Concussion, Depression, Football, Humans, Male, Middle Aged, Surveys and Questionnaires, Retirement, United States, Risk Assessment

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review