The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Physiologic Functions of Cyclophilin D and the Mitochondrial Permeability Transition Pore
Open accessAbstract
This review focuses on the role of cyclophilin D (CypD) as a prominent mediator of the mitochondrial permeability transition pore (MPTP) and subsequent effects on cardiovascular physiology and pathology. Although a great number of reviews have been written on the MPTP and its effects on cell death, we focus on the biology surrounding CypD itself and the non-cell death physiologic functions of the MPTP. A greater understanding of the physiologic functions of the MPTP and its regulation by CypD will likely suggest novel therapeutic approaches for cardiovascular disease, both dependent and independent of programmed necrotic cell death mechanisms.
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Cites
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Self-citationShimizu, S., Narita, M., Tsujimoto, Y., & Tsujimoto, Y. (1999) · Nature · doi:10.1038/20959 · Cited by 2,178
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Cited by
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
Zorov, D. B., Juhaszova, M., & Sollott, S. J. (2014) · Physiological Reviews · doi:10.1152/physrev.00026.2013 · Cited by 5,383
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
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Genome-wide enhancer maps link risk variants to disease genes
Nasser, J., Bergman, D. T., Fulco, C. P., Guckelberger, P., Doughty, B. R., Patwardhan, T. A., Jones, T. R., Nguyen, T. H., Ulirsch, J. C., Lekschas, F., et al. (2021) · Nature · doi:10.1038/s41586-021-03446-x · Cited by 669
Programmed cell death in aging
Tower, J. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.04.002 · Cited by 426
Mitochondrial calcium exchange in physiology and disease
Garbincius, J. F., & Elrod, J. W. (2022) · Physiological Reviews · doi:10.1152/physrev.00041.2020 · Cited by 412
Self-citation
Metadata
- Authors
- Elrod, J. W., & Molkentin, J. D.
- Venue
- Circulation Journal
- Publisher
- Japanese Circulation Society
- Published
- 2013
- Volume
- 77
- Issue
- 5
- Pages
- 1111-1122
- ISSN
- 1346-9843 (ISSN-L)
- 1347-4820
- OpenAlex
- W1966329382
- Cited by
- 266
- References
- 14
- FWCI
- 11.16
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Elrod, J. W., & Molkentin, J. D. (2013). Physiologic Functions of Cyclophilin D and the Mitochondrial Permeability Transition Pore. Circulation Journal. https://doi.org/10.1253/circj.cj-13-0321
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