The DOI matches its Crossref record; 18 of the 20 references it cites were found in a registry or an index.
Improved focal liver lesion detection: comparison of single-shot diffusion-weighted echoplanar and single-shot T2weighted turbo spin echo techniques
Abstract
The purpose of this study was to compare diffusion-weighted respiratory-triggered single-shot spin echo echoplanar imaging (SS SE-EPI) sequence using four b-values (b = 0, b = 20, b = 300, b = 800 s mm(-2)) and single-shot T2 weighted turbo spin echo (T2W SS TSE) in patients with focal liver lesions, with special interest in small (<10 mm) lesions. Twenty-four patients underwent routine MRI. The five sequences were compared qualitatively for image quality, lesion conspicuity and artefacts. Quantitative analysis was performed for lesion identification and lesion-to-liver contrast-to-noise ratio (CNR). Subgroup analyses were performed for different types of lesions with different sizes. Sequences were compared by rank order statistic (RIDIT) and Kruskal-Wallis test. The best image quality (p<0.05) was achieved with T2W TSE and the best lesion conspicuity (p<0.05) with T2W TSE for biliary cysts and SE-EPI diffusion-weighted imaging (DWI) (b = 20 s mm(-2)) for haemangiomas and metastases. Image artefacts were lowest (p<0.05) with T2W TSE. T2W TSE was found to be the best protocol (p<0.05) for the identification of biliary cysts and SE-EPI DWI (b = 20 s mm(-2)) for haemangiomas and metastases. The lesion-to-liver CNRs were highest on T2W TSE for biliary cysts and on SE-EPI diffusion-weighted imaging (DWI) for haemangiomas and metastases (p<0.05). This study shows the potential of SS SE-EPI DWI (especially with a b-value of 20 s mm(-2)) as a promising technique for detecting small (<10 mm) focal liver lesions.
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“Diffusion-weighted imaging may help to distinguish well-differentiated hepatocellular carcinomas from benign nodules [17,18], C Dionisi Vici and L Monti unpublished.”
From Recommendations for the management of tyrosinaemia type 1 (2013) · cites this paper as [17]
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Cited by
Diffusion-weighted MR Imaging of the Liver
Taouli, B., & Koh, D.-M. (2010) · Radiology · doi:10.1148/radiol.09090021 · Cited by 810
Recommendations for the management of tyrosinaemia type 1
de Laet, C., Dionisi-Vici, C., Leonard, J. V., McKiernan, P., Mitchell, G., Monti, L., de Baulny, H. O., Pintos-Morell, G., & Spiekerkötter, U. (2013) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-8-8 · Cited by 227
d’Assignies, G., Fina, P., Bruno, O., Vullierme, M.-P., Tubach, F., Paradis, V., Sauvanet, A., Ruszniewski, P., & Vilgrain, V. (2013) · Radiology · doi:10.1148/radiol.13121628 · Cited by 212
Diffusion-weighted MR Imaging of the Pancreas: Current Status and Recommendations
Barral, M., Taouli, B., Guiu, B., Koh, D.-M., Luciani, A., Manfredi, R., Vilgrain, V., Hoeffel, C., Kanematsu, M., & Soyer, P. (2015) · Radiology · doi:10.1148/radiol.14130778 · Cited by 208
Utility of diffusion‐weighted MRI in distinguishing benign and malignant hepatic lesions
Miller, F. H., Hammond, N., Siddiqi, A. J., Shroff, S., Khatri, G., Wang, Y., Merrick, L. B., & Nikolaidis, P. (2010) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.22235 · Cited by 188
Metadata
- Authors
- Coenegrachts, K., Delanote, J., Ter Beek, L., Haspeslagh, M., Bipat, S., Stoker, J., Van Kerkhove, F., Steyaert, L., Rigauts, H., & W Casselman, J.
- Affiliations
- Amsterdam UMC Location University of Amsterdam (NL)
- Venue
- The British Journal of Radiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-07
- Volume
- 80
- Issue
- 955
- Pages
- 524-531
- ISSN
- 0007-1285 (ISSN-L)
- 1748-880X
- OpenAlex
- W1966369454
- Cited by
- 149
- References
- 20
- Citations by year
- 2026: 4 · 2024: 3 · 2023: 4 · 2022: 5 · 2021: 5 · 2020: 4 · 2019: 3 · 2018: 5 · 2017: 5 · 2016: 8 · 2015: 9 · 2014: 10 · 2013: 18 · 2012: 20
- FWCI
- 9.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- British Journal of Radiology (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › MRI in cancer diagnosis
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Ultrasound Imaging and Elastography
- Keywords
- focal liver lesions, diffusion-weighted imaging, fast spin echo, T2-weighted imaging, small liver lesions, b-value, lesion conspicuity, contrast-to-noise ratio, biliary cysts, hepatic hemangioma, liver metastasis, image artifacts
- MeSH terms
- Aged, Bile Duct Diseases, Cysts, Female, Hemangioma, Humans, Image Interpretation, Computer-Assisted, Liver, Liver Diseases, Liver Neoplasms, Male, Middle Aged, Probability, Statistics as Topic, Artifacts, Echo-Planar Imaging, Diffusion Magnetic Resonance Imaging
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- CoChat. (2026). Citation check: Improved focal liver lesion detection: comparison of single-shot diffusion-weighted echoplanar and single-shot T2weighted turbo spin echo techniques. https://app.cochat.ai/papers/10.1259/bjr/33156643
- The paper
- Coenegrachts, K., Delanote, J., Ter Beek, L., Haspeslagh, M., Bipat, S., Stoker, J., Van Kerkhove, F., Steyaert, L., Rigauts, H., & W Casselman, J. (2007). Improved focal liver lesion detection: comparison of single-shot diffusion-weighted echoplanar and single-shot T2weighted turbo spin echo techniques. The British Journal of Radiology. https://doi.org/10.1259/bjr/33156643
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
