The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Role of quorum sensing in bacterial infections
Open accessAbstract
Quorum sensing (QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate that QS enhances virulence of bacterial pathogens in animal models as well as in human infections; however, its relative importance for bacterial pathogenesis is still incomplete. In this review, we discuss the present evidence from in vitro and in vivo experiments in animal models, as well as from clinical studies, that link QS systems with human infections. We focus on two major QS bacterial models, the opportunistic Gram negative bacteria Pseudomonas aeruginosa and the Gram positive Staphylococcus aureus, which are also two of the main agents responsible of nosocomial and wound infections. In addition, QS communication systems in other bacterial, eukaryotic pathogens, and even immune and cancer cells are also reviewed, and finally, the new approaches proposed to combat bacterial infections by the attenuation of their QS communication systems and virulence are also discussed.
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Cites
Quorum Sensing in the Dimorphic Fungus Candida albicans Is Mediated by Farnesol
Hornby, J. M., Jensen, E. C., Lisec, A. D., Tasto, J. J., Jahnke, B., Shoemaker, R., Dussault, P., & Nickerson, K. W. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.7.2982-2992.2001 · Cited by 983
Contribution of Quorum Sensing to the Virulence of Pseudomonas aeruginosa in Burn Wound Infections
Rumbaugh, K. P., Griswold, J. A., Iglewski, B. H., & Hamood, A. N. (1999) · Infection and Immunity · doi:10.1128/iai.67.11.5854-5862.1999 · Cited by 408
Analysis of quorum sensing-deficient clinical isolates of Pseudomonas aeruginosa
Schaber, J. A., Carty, N. L., McDonald, N. A., Graham, E. D., Cheluvappa, R., Griswold, J. A., & Hamood, A. N. (2004) · Journal of Medical Microbiology · doi:10.1099/jmm.0.45617-0 · Cited by 224
Nafee, N., Husari, A., Maurer, C. K., Lu, C., de Rossi, C., Steinbach, A., Hartmann, R. W., Lehr, C.-M., & Schneider, M. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.06.055 · Cited by 208
QseC Mediates Salmonella enterica Serovar Typhimurium Virulence In Vitro and In Vivo
Moreira, C. G., Weinshenker, D., & Sperandio, V. (2010) · Infection and Immunity · doi:10.1128/iai.01038-09 · Cited by 195
Cited by
Falanga, V., Isseroff, R. R., Soulika, A. M., Romanelli, M., Margolis, D., Kapp, S., Granick, M., & Harding, K. (2022) · Nature Reviews Disease Primers · doi:10.1038/s41572-022-00377-3 · Cited by 1,020
Bodelón, G., Montes-García, V., López-Puente, V., Hill, E. H., Hamon, C., Sanz-Ortiz, M. N., Rodal-Cedeira, S., Costas, C., Celiksoy, S., Pérez-Juste, I., et al. (2016) · Nature Materials · doi:10.1038/nmat4720 · Cited by 359
Borges, A., Abreu, A., Dias, C., Saavedra, M., Borges, F., & Simões, M. (2016) · Molecules · doi:10.3390/molecules21070877 · Cited by 308
Metadata
- Authors
- Castillo-Juárez, I., Maeda, T., Mandujano-Tinoco, E. A., Tomás, M., Pérez-Eretza, B., García-Contreras, S. J., Wood, T. K., & García-Contreras, R.
- Venue
- World Journal of Clinical Cases
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2015
- Volume
- 3
- Issue
- 7
- Pages
- 575
- ISSN
- 2307-8960 (ISSN-L)
- OpenAlex
- W2306122989
- Cited by
- 218
- References
- 5
- FWCI
- 7.72
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Castillo-Juárez, I., Maeda, T., Mandujano-Tinoco, E. A., Tomás, M., Pérez-Eretza, B., García-Contreras, S. J., Wood, T. K., & García-Contreras, R. (2015). Role of quorum sensing in bacterial infections. World Journal of Clinical Cases. https://doi.org/10.12998/wjcc.v3.i7.575
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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