The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Longitudinal Changes in BMD and Bone Geometry in a Population-Based Study
Abstract
We prospectively examined vBMD and structural bone parameters assessed by QCT among participants of the InCHIANTI study over a 6-yr follow-up. Periosteal apposition occurred both in men and women. Endocortical resorption causes bone loss in older women despite periosteal apposition. Introduction: To address the hypothesis that age-related changes in BMD and bone geometry may be different in men and women, we prospectively examined volumetric BMD (vBMD) and structural bone parameters assessed by QCT among participants of the InCHIANTI study over a 6-yr follow-up. Materials and Methods: Three hundred forty-five men and 464 women 21–102 yr of age from the InCHIANTI study, a population-based study in Tuscany, Italy, were included. Tibial QCT bone parameters were measured at enrollment (1998–2000) and at 3- (2001–2003) and 6-yr (2004–2006) follow-ups. Results: Periosteal apposition occurred both in men and women. The annual rate of bone periosteal apposition was higher in younger than in older men, whereas in women, the rate of apposition was homogenous across age groups. The age-related medullary expansion, expression of endocortical resorption, was significantly higher in women compared with men. In women, but not in men, accelerated endocortical resorption not sufficiently balanced by periosteal apposition caused accelerated loss in cortical bone mass. The cross-sectional moment of inertia decreased progressively over the life span in both sexes. Conclusions: Endocortical resorption causes bone loss in older women despite periosteal apposition. Obtaining a balance between endocortical resorption and periosteal apposition should be the target for interventions aimed to decrease bone loss and prevent osteoporosis in older women.
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“Continuous periosteal apposition was reported, especially during young adulthood and midlife.”
From Regular Strength and Sprint Training Counteracts Bone Aging: A 10‐Year Follow‐Up in Male Masters Athletes (2021) · cites this paper as [50]
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“Similarly, by combining cross‐sectional and longitudinal data, Lauretani and colleagues( 50 ) observed significant lifetime decreases (approximately −20% between ages 20 and 100 years) in distal tibia total and trabecular vBMD measured by pQCT.”
From Regular Strength and Sprint Training Counteracts Bone Aging: A 10‐Year Follow‐Up in Male Masters Athletes (2021) · cites this paper as [50]
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“Furthermore, in accordance with Lauretani and colleagues,( 50 ) we found that the cross‐sectional linear trends derived from the baseline data were poor predictors of the longitudinal changes in bone (Supplemental Table S2).”
From Regular Strength and Sprint Training Counteracts Bone Aging: A 10‐Year Follow‐Up in Male Masters Athletes (2021) · cites this paper as [50]
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“At the mid‐tibia site, Lauretani and colleagues( 50 ) reported slight age‐related increases in cortical and total CSA, particularly before midlife. However, estimated bending strength declined over the life span.”
From Regular Strength and Sprint Training Counteracts Bone Aging: A 10‐Year Follow‐Up in Male Masters Athletes (2021) · cites this paper as [50]
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Cited by
Estrogens and androgens in skeletal physiology and pathophysiology
Almeida, M., Laurent, M. R., Dubois, V., Claessens, F., O'Brien, C. A., Bouillon, R., Vanderschueren, D., & Manolagas, S. C. (2017) · Physiological Reviews · doi:10.1152/physrev.00033.2015 · Cited by 860
Sex Steroid Actions in Male Bone
Vanderschueren, D., Laurent, M. R., Claessens, F., Gielen, E., Lagerquist, M. K., Vandenput, L., Börjesson, A. E., & Ohlsson, C. (2014) · Endocrine Reviews · doi:10.1210/er.2014-1024 · Cited by 327
Johannesdottir, F., Aspelund, T., Siggeirsdottir, K., Jonsson, B. Y., Mogensen, B., Sigurdsson, S., Harris, T. B., Gudnason, V. G., Lang, T. F., & Sigurdsson, G. (2012) · Calcified Tissue International · doi:10.1007/s00223-012-9585-6 · Cited by 52
Suominen, T. H., Alén, M., Törmäkangas, T., Degens, H., Rittweger, J., Heinonen, A., Suominen, H., & Korhonen, M. T. (2021) · JBMR Plus · doi:10.1002/jbm4.10513 · Cited by 17
Metadata
- Authors
- Lauretani, F., Bandinelli, S., Griswold, M. E., Maggio, M., Semba, R., Guralnik, J. M., & Ferrucci, L.
- Affiliations
- Longitudinal Studies Section, Clinical Research Branch, NIA-NIH, Bethesda, Maryland, USA
- Geriatric Unit, Azienda Sanitaria Firenze, Florence, Italy
- Johns Hopkins School of Medicine, Baltimore, Maryland, USA
- Department of Internal Medicine and Biomedical Sciences, Section of Geriatrics, University of Parma, Parma, Italy
- Laboratory of Epidemiology, Demography and Biometry, NIA-NIH, Bethesda, Maryland, USA
- Venue
- Journal of Bone and Mineral Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-03-01
- Volume
- 23
- Issue
- 3
- Pages
- 400-408
- ISSN
- 0884-0431
- 1523-4681
- Cited by
- 110
- References
- 5
- Language
- en
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