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What is replication?
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Abstract
Credibility of scientific claims is established with evidence for their replicability using new data. According to common understanding, replication is repeating a study's procedure and observing whether the prior finding recurs. This definition is intuitive, easy to apply, and incorrect. We propose that replication is a study for which any outcome would be considered diagnostic evidence about a claim from prior research. This definition reduces emphasis on operational characteristics of the study and increases emphasis on the interpretation of possible outcomes. The purpose of replication is to advance theory by confronting existing understanding with new evidence. Ironically, the value of replication may be strongest when existing understanding is weakest. Successful replication provides evidence of generalizability across the conditions that inevitably differ from the original study; Unsuccessful replication indicates that the reliability of the finding may be more constrained than recognized previously. Defining replication as a confrontation of current theoretical expectations clarifies its important, exciting, and generative role in scientific progress.
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Small adjustments to the overall study do not diminish the replicatory nature and value of the new scholarship.
“Furthermore, they argued that small adjustments to the overall study do not diminish the replicatory nature and value of the new scholarship.”
From Examining Counselor Trainees’ Clinical Impressions of Pornography Use: Implications for Couple and Family Counselors (2026) · cites this paper as Nosek and Errington (2020)
In “Replication redux,” the authors define replication by whether its outcomes test a prior claim, rather than by exact repetition of procedures. This supports the idea that adjustments need not disqualify a study as a replication. But “Replication resolved” explains that a seemingly small difference can matter: seasonal differences in frogs meant some attempted replications were not studying the same thing. The claim is too categorical in saying small adjustments do not diminish replicatory status. (LLM, conf=0.85)
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Palmer, L., Brooks, G. A., & Clark, L. (2025) · BMC Psychology · doi:10.1186/s40359-025-02766-1 · Cited by 20
Replication, Uncertainty and Progress in Comparative Cognition
Boyle, A. (2021) · Animal Behavior and Cognition · doi:10.26451/abc.08.02.15.2021 · Cited by 20
Krüppel, J., Yoon, D., & Mokros, A. (2022) · Personality and Individual Differences · doi:10.1016/j.paid.2022.111966 · Cited by 20
Building reproducible bridges to cross the “valley of death”
Errington, T. M. (2024) · Journal of Clinical Investigation · doi:10.1172/jci177383 · Cited by 20
Self-citationWhiteside, D. M., Basso, M. R., Shen, C., Fry, L., Naini, S. M., Waldron, E. J., Holker, E. G., Porter, J., Eskridge, C. L. M., Logemann, A., et al. (2024) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2024.2312625 · Cited by 20
Williamson, P. C., Pörtner, H., Widdicombe, S., & Gattuso, J. (2021) · Biogeosciences · doi:10.5194/bg-18-1787-2021 · Cited by 20
Farrar, B. G., Ostojić, L., & Clayton, N. S. (2021) · PLoS ONE · doi:10.1371/journal.pone.0256607 · Cited by 20
The future of replication in applied linguistics: Toward a standard for replication studies
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Exploring risk factors and determinants: A scoping review of factors associated with nomophobia
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Over-optimism in unsupervised microbiome analysis: Insights from network learning and clustering
Ullmann, T., Peschel, S., Finger, P., Müller, C. L., & Boulesteix, A. (2023) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010820 · Cited by 18
Ng, J. Y., Lee, M. S., Liu, J., Steel, A., Wieland, L. S., Witt, C. M., Moher, D., & Cramer, H. (2024) · Integrative Medicine Research · doi:10.1016/j.imr.2024.101068 · Cited by 18
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Self-citationReply to: Methods matter in repeating ocean acidification studies
Clark, T. D., Raby, G. D., Roche, D. G., Binning, S. A., Speers‐Roesch, B., Jutfelt, F., & Sundin, J. (2020) · Nature · doi:10.1038/s41586-020-2804-9 · Cited by 18
Metadata
- Authors
- Nosek, B. A., & Errington, T. M.
- Affiliations
- Center for Open Science (US)
- Corresponding author
- Nosek, Brian A.
- Venue
- PLOS Biology
- Publisher
- Public Library of Science (PLoS)
- Published
- 2020-03-27
- Volume
- 18
- Issue
- 3
- Pages
- e3000691
- ISSN
- 1544-9173 (ISSN-L)
- 1545-7885
- PMC
- PMC7100931
- OpenAlex
- W3013926312
- Cited by
- 444
- References
- 14
- Citations by year
- 2026: 59 · 2025: 78 · 2024: 77 · 2023: 65 · 2022: 61 · 2021: 71 · 2020: 29
- FWCI
- 20.64
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS Biology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- OSF Preprints (OSF Preprints) (submittedVersion, public-domain)
- MetArXiv (OSF Preprints) (submittedVersion)
- OSF Preprints (OSF Preprints) (submittedVersion)
- MetArXiv (OSF Preprints) (submittedVersion, public-domain)
- Funders
- John Templeton Foundation
- Arnold Ventures
- Templeton World Charity Foundation
- Templeton Religion Trust
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy of Biology and Scientific Explanation
- Social Sciences › Library and Information Sciences › Academic Publishing and Open Access
- Keywords
- replication, diagnostic findings, generalizability, scientific progress, theory testing
- MeSH terms
- Data Interpretation, Statistical, Humans, Research Design, Statistics as Topic, Reproducibility of Results
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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