Cited by 36Artificial Intelligence in Healthcare and EducationElectronic Health Records SystemsHealth Policy Implementation Science

Frameworks for procurement, integration, monitoring, and evaluation of artificial intelligence tools in clinical settings: A systematic review

Open access
Khan, Sarim Dawar, Hoodbhoy, Zahra, Raja, Mohummad Hassan Raza, Kim, Jee Young, Hogg, Henry David Jeffry, Manji, Afshan Anwar Ali, Gulamali, Freya, Hasan, Alifia +7 more·2024·PLOS Digital Health

Abstract

Research on the applications of artificial intelligence (AI) tools in medicine has increased exponentially over the last few years but its implementation in clinical practice has not seen a commensurate increase with a lack of consensus on implementing and maintaining such tools. This systematic review aims to summarize frameworks focusing on procuring, implementing, monitoring, and evaluating AI tools in clinical practice. A comprehensive literature search, following PRSIMA guidelines was performed on MEDLINE, Wiley Cochrane, Scopus, and EBSCO databases, to identify and include articles recommending practices, frameworks or guidelines for AI procurement, integration, monitoring, and evaluation. From the included articles, data regarding study aim, use of a framework, rationale of the framework, details regarding AI implementation involving procurement, integration, monitoring, and evaluation were extracted. The extracted details were then mapped on to the Donabedian Plan, Do, Study, Act cycle domains. The search yielded 17,537 unique articles, out of which 47 were evaluated for inclusion based on their full texts and 25 articles were included in the review. Common themes extracted included transparency, feasibility of operation within existing workflows, integrating into existing workflows, validation of the tool using predefined performance indicators and improving the algorithm and/or adjusting the tool to improve performance. Among the four domains (Plan, Do, Study, Act) the most common domain was Plan (84%, n = 21), followed by Study (60%, n = 15), Do (52%, n = 13), & Act (24%, n = 6). Among 172 authors, only 1 (0.6%) was from a low-income country (LIC) and 2 (1.2%) were from lower-middle-income countries (LMICs). Healthcare professionals cite the implementation of AI tools within clinical settings as challenging owing to low levels of evidence focusing on integration in the Do and Act domains. The current healthcare AI landscape calls for increased data sharing and knowledge translation to facilitate common goals and reap maximum clinical benefit.

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  • The feasibility of lifecycle governance is likely to vary substantially across health systems because many recommendations assume access to data infrastructure, informatics expertise, technical staffing, procurement capacity, legal support, regulatory maturity, and multidisciplinary oversight structures.

    “The feasibility of lifecycle governance is likely to vary substantially across health systems because many recommendations assume access to data infrastructure, informatics expertise, technical staffing, procurement capacity, legal support, regulatory maturity, and multidisciplinary oversight structures [49,50,51,52].”

    From Beyond Model Development in Healthcare AI: Post-Development Robustness, Post-Deployment Monitoring, and Lifecycle Governance—A Scoping Review of Reviews (2026) · cites this paper as [49]

    Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.

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  • These assumptions may not hold equally across low- and middle-income countries, smaller hospitals, rural systems, or institutions with limited digital maturity, where the infrastructure required for continuous monitoring, subgroup surveillance, drift detection, formal change control, and incident response may be more difficult to sustain.

    “These assumptions may not hold equally across low- and middle-income countries, smaller hospitals, rural systems, or institutions with limited digital maturity, where the infrastructure required for continuous monitoring, subgroup surveillance, drift detection, formal change control, and incident response may be more difficult to sustain [49,50,51,52].”

    From Beyond Model Development in Healthcare AI: Post-Development Robustness, Post-Deployment Monitoring, and Lifecycle Governance—A Scoping Review of Reviews (2026) · cites this paper as [49]

    Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.

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  • Without a shared framework, emergency departments struggle to distinguish safe AI tools from risky ones.

    “Without a shared framework, departments struggle to distinguish safe tools from risky ones,30, 31, 32”

    From Artificial Intelligence Readiness in Emergency Medicine: Expert Consensus Opinion for Preparing the Workforce (2026) · cites this paper as [32]

    The Introduction identifies a lack of a systematic approach to AI procurement and implementation as a barrier, and the Conclusion says healthcare professionals find implementation challenging with little guidance. The paper discusses evaluating AI tools and their risks, but it does not specifically establish that emergency departments struggle to distinguish safe tools from risky ones. (LLM, conf=0.84)

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  • Inadequate assessment of a potential partner's financial sustainability risks committing substantial clinical and technical resources to a partnership that may ultimately fail.

    “Inadequate assessment of a potential partner’s financial sustainability risks committing substantial clinical and technical resources to a partnership that may ultimately fail.32,45”

    From Artificial Intelligence Readiness in Emergency Medicine: Expert Consensus Opinion for Preparing the Workforce (2026) · cites this paper as [32]

    The Results > Themes section (page not provided) says purchasing and implementation costs should be assessed in advance to ensure an AI tool is financially sustainable. It does not address a potential partner’s financial sustainability or say that failing to assess it risks committing clinical and technical resources to a partnership that may fail. (LLM, conf=0.78)

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  • Much of the review literature addressed governance architectures, robustness concepts, implementation barriers, monitoring frameworks, MLOps, or deployment-proximal evaluation, rather than mature evidence generated during sustained routine deployment.

    “Much of the review literature instead addressed governance architectures, robustness concepts, implementation barriers, monitoring frameworks, MLOps, or deployment-proximal evaluation, rather than mature evidence generated during sustained routine deployment [18,19,20,29,35,37,47,49].”

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Authors
Khan, S. D., Hoodbhoy, Z., Raja, M. H. R., Kim, J. Y., Hogg, H. D. J., Manji, A. A. A., Gulamali, F., Hasan, A., Shaikh, A., Tajuddin, S., Khan, N. S., Patel, M. R., Balu, S., Samad, Z., & Sendak, M. P.
Affiliations
  • Aga Khan University (PK)
  • Duke University (US)
  • Moorfields Eye Hospital NHS Foundation Trust (GB)
Corresponding author
Sendak, Mark P.
Venue
PLOS Digital Health
Published
2024-05-29
Volume
3
Issue
5
Pages
e0000514
ISSN
2767-3170 (ISSN-L)
OpenAlex
W4399118706
Cited by
36
References
62
Citations by year
2026: 22 · 2025: 12 · 2024: 2
FWCI
0.82
Type
journal article
Language
en
Open access
Locations
  • PLOS Digital Health (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • eCommons - AKU (Aga Khan University) (submittedVersion, cc-by)
  • RePEc: Research Papers in Economics (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • Newcastle University ePrints (Newcastle Univesity) (cc-by)
Funders
Patrick J. McGovern Foundation (383000239)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
  • Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
Keywords
artificial intelligence in healthcare, AI procurement, clinical implementation of AI, AI transparency, low-income countries, knowledge translation, data sharing

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