The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
The Genome of Nectria haematococca: Contribution of Supernumerary Chromosomes to Gene Expansion
Open accessAbstract
The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of >50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on >100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches.
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Cites
Gene Ontology: tool for the unification of biology
Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., et al. (2000) · Nature Genetics · doi:10.1038/75556 · Cited by 43,206
The Statistical Analysis of Compositional Data
Aitchison, J. (1986) · doi:10.1007/978-94-009-4109-0 · Cited by 4,383
Lateral gene transfer and the nature of bacterial innovation
Ochman, H., Lawrence, J. G., & Groisman, E. A. (2000) · Nature · doi:10.1038/35012500 · Cited by 3,816
Multistate Outbreak of Fusarium Keratitis Associated With Use of a Contact Lens Solution
Chang, D. C., Grant, G. B., O’Donnell, K., Wannemuehler, K. A., Noble-Wang, J., Rao, C. Y., Jacobson, L. M., Crowell, C. S., Sneed, R. S., Lewis, F. M. T., et al. (2006) · JAMA · doi:10.1001/jama.296.8.953 · Cited by 600
Genomic Islands in the Pathogenic Filamentous Fungus Aspergillus fumigatus
Fedorova, N. D., Khaldi, N., Joardar, V. S., Maiti, R., Amedeo, P., Anderson, M. J., Crabtree, J., Silva, J. C., Badger, J. H., Albarraq, A., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000046 · Cited by 508 · cited 10×
“Nevertheless, the ability of N. haematococca MPVI to acquire genes by HGT or a similar mechanism would bypass the evolutionary restraint that an active RIP system places on a fungus by hindering the utility of gene duplications as a means to create new genes functions [50].”
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The Ecology and Evolution of Pangenomes
Brockhurst, M. A., Harrison, E., Hall, J. P. J., Richards, T., McNally, A., & MacLean, C. (2019) · Current Biology · doi:10.1016/j.cub.2019.08.012 · Cited by 385
Ploidy Variation in Fungi: Polyploidy, Aneuploidy, and Genome Evolution
Todd, R. T., Forche, A., & Selmecki, A. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.funk-0051-2016 · Cited by 121
Gan, P., Narusaka, M., Kumakura, N., Tsushima, A., Takano, Y., Narusaka, Y., & Shirasu, K. (2016) · Genome Biology and Evolution · doi:10.1093/gbe/evw089 · Cited by 98
Metadata
- Authors
- Coleman, J. J., Rounsley, S. D., Rodriguez-Carres, M., Kuo, A., Wasmann, C. C., Grimwood, J., Schmutz, J., Taga, M., White, G. J., Zhou, S., Schwartz, D. C., Freitag, M., Ma, L.-J., Danchin, E. G. J., Henrissat, B., Coutinho, P. M., Nelson, D. R., Straney, D., Napoli, C. A., Barker, B. M., Gribskov, M., Rep, M., Kroken, S., Molnár, I., Rensing, C., Kennell, J. C., Zamora, J., Farman, M. L., Selker, E. U., Salamov, A., Shapiro, H., Pangilinan, J., Lindquist, E., Lamers, C., Grigoriev, I. V., Geiser, D. M., Covert, S. F., Temporini, E., & VanEtten, H. D.
- Venue
- PLoS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2009-08-28
- Volume
- 5
- Issue
- 8
- Pages
- e1000618
- ISSN
- 1553-7390 (ISSN-L)
- 1553-7404
- OpenAlex
- W2121517534
- Cited by
- 469
- References
- 5
- FWCI
- 9.48
- Type
- journal article
- Language
- en
- Open access
- gold
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