Global DNA Hypermethylation in Down Syndrome Placenta

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome.

Langmead, B., Trapnell, C., Pop, M., & Salzberg, S. L. (2009) · Genome Biology · doi:10.1186/gb-2009-10-3-r25 · Cited by 21,849 · see citing works

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L. M., Liu, D. R., Aravind, L., et al. (2009) · Science · doi:10.1126/science.1170116 · Cited by 5,836 · see citing works

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Amir, R. E., Van den Veyver, I. B., Wan, M., Tran, C. Q., Francke, U., & Zoghbi, H. Y. (1999) · Nature Genetics · doi:10.1038/13810 · Cited by 4,990 · see citing works

Human DNA methylomes at base resolution show widespread epigenomic differences

Lister, R., Pelizzola, M., Dowen, R. H., Hawkins, R. D., Hon, G., Tonti-Filippini, J., Nery, J. R., Lee, L., Ye, Z., Ngo, Q.-M., et al. (2009) · Nature · doi:10.1038/nature08514 · Cited by 4,673 · see citing works

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

Ito, S., Shen, L., Dai, Q., Wu, S. C., Collins, L. B., Swenberg, J. A., He, C., & Zhang, Y. (2011) · Science · doi:10.1126/science.1210597 · Cited by 3,451 · see citing works

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

He, Y., Li, B.-Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, L., et al. (2011) · Science · doi:10.1126/science.1210944 · Cited by 2,776 · see citing works

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Meissner, A., Mikkelsen, T. S., Gu, H., Wernig, M., Hanna, J., Sivachenko, A., Zhang, X., Bernstein, B. E., Nusbaum, C., Jaffe, D. B., et al. (2008) · Nature · doi:10.1038/nature07107 · Cited by 2,536 · see citing works

DNA-binding factors shape the mouse methylome at distal regulatory regions

Stadler, M. B., Murr, R., Burger, L., Ivanek, R., Lienert, F., Schöler, A., Nimwegen, E. V., Wirbelauer, C., Oakeley, E. J., Gaidatzis, D., et al. (2011) · Nature · doi:10.1038/nature10716 · Cited by 1,383 · see citing works

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

Guo, J. U., Su, Y., Zhong, C., Ming, G., & Song, H. (2011) · Cell · doi:10.1016/j.cell.2011.03.022 · Cited by 1,355 · see citing works

DNA methylation profiling of human chromosomes 6, 20 and 22

Eckhardt, F., Lewin, J., Cortese, R., Rakyan, V. K., Attwood, J., Burger, M., Burton, J. H., Cox, T. V., Davies, R., Down, T. A., et al. (2006) · Nature Genetics · doi:10.1038/ng1909 · Cited by 1,350 · see citing works

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

Ficz, G., Branco, M. R., Seisenberger, S., Santos, F., Krueger, F., Hore, T. A., Marques, C. J., Andrews, S., & Reik, W. (2011) · Nature · doi:10.1038/nature10008 · Cited by 1,123 · see citing works

Dynamic changes in the human methylome during differentiationPreprint

Laurent, L. C., Wong, E., Li, G., Huynh, T., Tsirigos, A., Ong, C. T., Low, H. M., Sung, K. W. K., Rigoutsos, I., Loring, J. F., et al. (2010) · Genome Research · doi:10.1101/gr.101907.109 · Cited by 1,037 · see citing works

Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome

Yu, M., Hon, G. C., Szulwach, K. E., Song, C., Zhang, L., Kim, A., Li, X., Dai, Q., Shen, Y., Park, B., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.027 · Cited by 1,022 · see citing works

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

Feng, J., Zhou, Y., Campbell, S. L., Le, T., Li, E., Sweatt, J. D., Silva, A. J., & Fan, G. (2010) · Nature Neuroscience · doi:10.1038/nn.2514 · Cited by 1,019 · see citing works

The UCSC Genome Browser database: extensions and updates 2013

Meyer, L. R., Zweig, A. S., Hinrichs, A. S., Karolchik, D., Kuhn, R. M., Wong, M., Sloan, C. A., Rosenbloom, K. R., Roe, G. R., Rhead, B. L., et al. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1048 · Cited by 901 · see citing works

Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development

Dawlaty, M. M., Ganz, K., Powell, B. E., Hu, Y.-C., Markoulaki, S., Cheng, A. W., Gao, Q., Kim, J., Choi, S.-W., Page, D. C., et al. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.07.010 · Cited by 508 · see citing works

The genetic architecture of down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

Korbel, J. O., Tirosh-Wagner, T., Urban, A. E., Chen, X.-N., Kasowski, M., Dai, L., Grubert, F., Erdman, C., Gao, M. C., Lange, K., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813248106 · Cited by 399 · see citing works

Genotype-phenotype correlations in down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21

Lyle, R., Béna, F., Gagos, S., Gehrig, C., Lopez, G., Schinzel, A., Lespinasse, J., Bottani, A., Dahoun, S., Taine, L., et al. (2009) · European Journal of Human Genetics · doi:10.1038/ejhg.2008.214 · Cited by 331 · see citing works

Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with down syndrome and in Ts65Dn mice

Contestabile, A., Fila, T., Ceccarelli, C., Bonasoni, P., Bonapace, L., Santini, D., Bartesaghi, R., & Ciani, E. (2007) · Hippocampus · doi:10.1002/hipo.20308 · Cited by 281 · see citing works

RESEARCH ARTICLE: Neurogenesis Impairment and Increased Cell Death Reduce Total Neuron Number in the Hippocampal Region of Fetuses with Down Syndrome

Guidi, S., Bonasoni, P., Ceccarelli, C., Santini, D., Gualtieri, F., Ciani, E., & Bartesaghi, R. (2008) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00113.x · Cited by 276 · see citing works

In psychosis, cortical interneurons overexpress DNA-methyltransferase 1

Veldić, M., Guidotti, A., Maloku, E., Davis, J. M., & Costa, E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409665102 · Cited by 269 · see citing works

Olig1 and Olig2 triplication causes developmental brain defects in down syndrome.

Chakrabarti, L., Best, T. K., Cramer, N. P., Carney, R. S. E., Isaac, J. T. R., Galdzicki, Z., & Haydar, T. F. (2010) · Nature Neuroscience · doi:10.1038/nn.2600 · Cited by 258 · see citing works

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

Kahlem, P., Sultan, M., Herwig, R., Steinfath, M., Balzereit, D., Eppens, B., Saran, N. G., Pletcher, M. T., South, S. T., Stetten, G., et al. (2004) · Genome Research · doi:10.1101/gr.1951304 · Cited by 249 · see citing works

Homocysteine Metabolism in Children with Down Syndrome: In Vitro Modulation

Pogribna, M., Melnyk, S., Pogribny, I. P., Chango, A., Yi, P., & James, S. J. (2001) · The American Journal of Human Genetics · doi:10.1086/321262 · Cited by 241 · see citing works

Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study

Bahn, S., Mimmack, M., Ryan, M., Caldwell, M. A., Jauniaux, E., Starkey, M., Svendsen, C. N., & Emson, P. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07497-4 · Cited by 211 · see citing works

Global up-regulation of chromosome 21 gene expression in the developing down syndrome brain

Mao, R., Zielke, C. L., Ronald Zielke, H., & Pevsner, J. (2003) · Genomics · doi:10.1016/s0888-7543(03)00035-1 · Cited by 207 · see citing works

Function and regulation of Dyrk1A: towards understanding Down syndrome

Park, J., Song, W., & Chung, K. C. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0123-2 · Cited by 205 · see citing works

Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down SyndromePreprint

Lyle, R., Gehrig, C., Neergaard-Henrichsen, C., Deutsch, S., & Antonarakis, S. E. (2004) · Genome Research · doi:10.1101/gr.2090904 · Cited by 202 · see citing works

Transcriptome analysis of human autosomal trisomy

FitzPatrick, D. R. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.26.3249 · Cited by 198 · see citing works

Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors

Novakovic, B., Yuen, R. K. C., Gordon, L., Peñaherrera, M. S., Sharkey, A., Moffett, A., Craig, J. M., Robinson, W. P., & Saffery, R. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-529 · Cited by 192 · see citing works

DNA Methylation Analysis of Chromosome 21 Gene Promoters at Single Base Pair and Single Allele Resolution

Zhang, Y., Rohde, C., Tierling, S., Jurkowski, T. P., Bock, C., Santacruz, D., Ragozin, S., Reinhardt, R., Groth, M., Walter, J., et al. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000438 · Cited by 162 · see citing works

DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome

Canzonetta, C., Mulligan, C., Deutsch, S., Ruf, S., O’Doherty, A., Lyle, R., Borel, C., Lin-Marq, N., Delom, F., Groet, J., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.08.012 · Cited by 158 · see citing works

DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome

Lepagnol-Bestel, A.-M., Zvara, Á., Maussion, G., Quignon, F., Ngimbous, B., Ramoz, N., Imbeaud, S., Loe-Mie, Y., Benihoud, K., Agier, N., et al. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp047 · Cited by 137 · see citing works

Systematic Search for Placental DNA-Methylation Markers on Chromosome 21: Toward a Maternal Plasma-Based Epigenetic Test for Fetal Trisomy 21

Chim, S. S. C., Jin, S., Lee, T. Y. H., Lun, F. M. F., Lee, W. S., Chan, L. Y. S., Jin, Y., Yang, N., Tong, Y. K., Leung, T. Y., et al. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.098731 · Cited by 133 · see citing works

Sites of Differential DNA Methylation between Placenta and Peripheral Blood

Papageorgiou, E. A., Fiegler, H., Rakyan, V. K., Beck, S., Hultén, M. A., Lamnissou, K., Carter, N. P., & Patsalis, P. C. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.081038 · Cited by 116 · see citing works

Altered DNA Methylation in Leukocytes with Trisomy 21

Kerkel, K., Schupf, N., Hatta, K., Pang, D. I., Salas, M. C., Kratz, A. F., Minden, M. D., Murty, V. V. V. S., Zigman, W. B., Mayeux, R. P., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001212 · Cited by 114 · see citing works

Significance analysis and statistical dissection of variably methylated regions

Jaffe, A. E., Feinberg, A. P., Irizarry, R. A., & Leek, J. T. (2011) · Biostatistics · doi:10.1093/biostatistics/kxr013 · Cited by 100 · see citing works

Is it possible to improve neurodevelopmental abnormalities in Down syndrome?

Bartesaghi, R., Guidi, S., & Ciani, E. (2011) · Reviews in the Neurosciences · doi:10.1515/rns.2011.037 · Cited by 74 · see citing works

Massive-Scale RNA-Seq Analysis of Non Ribosomal Transcriptome in Human Trisomy 21

Costa, V., Angelini, C., D’Apice, L., Mutarelli, M., Casamassimi, A., Sommese, L., Gallo, M. A., Aprile, M., Esposito, R., Leone, L., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018493 · Cited by 70 · see citing works

A microarray‐based approach for the identification of epigenetic biomarkers for the noninvasive diagnosis of fetal disease

Chu, T., Burke, B., Bunce, K. D., Surti, U., Hogge, W. A., & Peters, D. G. (2009) · Prenatal Diagnosis · doi:10.1002/pd.2335 · Cited by 57 · see citing works

Gene Network Disruptions and Neurogenesis Defects in the Adult Ts1Cje Mouse Model of Down Syndrome

Hewitt, C., Ling, K., Merson, T. D., Simpson, K., Ritchie, M. E., King, S. L., Pritchard, M. A., Smyth, G. K., Thomas, T., Scott, H. S., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011561 · Cited by 55 · see citing works

On the Promise of Pharmacotherapies Targeted at Cognitive and Neurodegenerative Components of Down Syndrome

Costa, A. C. S. (2011) · Developmental Neuroscience · doi:10.1159/000330861 · Cited by 44 · see citing works

Genome-wide expression analysis of cultured trophoblast with trisomy 21 karyotype

Rozovski, U., Grossman-Jonish, A., Bar‐Shira, A., Ochshorn, Y., Goldstein, M., & Yaron, Y. (2007) · Human Reproduction · doi:10.1093/humrep/dem214 · Cited by 43 · see citing works

DNA-Methylation Profiling of Fetal Tissues Reveals Marked Epigenetic Differences between Chorionic and Amniotic Samples

Eckmann-Scholz, C., Bens, S., Kolarova, J., Schneppenheim, S., Caliebe, A., Heidemann, S., von Kaisenberg, C., Kautza, M., Jonat, W., Siebert, R., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039014 · Cited by 40 · see citing works

REST: Transcriptional and Epigenetic Regulator

Bithell, A. (2011) · Epigenomics · doi:10.2217/epi.10.76 · Cited by 35 · see citing works

Aberrant epigenetic landscape in intellectual disability

Sanchez-Mut, J. V., Huertas, D., & Esteller, M. (2012) · Progress in brain research · doi:10.1016/b978-0-444-54299-1.00004-2 · Cited by 30 · see citing works

Mannan-binding lectin deficiency increases the risk of recurrent infections in children with Down's syndrome

Nisihara, R., Utiyama, S. R. R., Oliveira, N. P., & Messias-Reason, I. (2009) · Human Immunology · doi:10.1016/j.humimm.2009.09.361 · Cited by 28 · see citing works

Down Syndrome: A Complex and Interactive Genetic Disorder

Samantha, L., Joshua, D., Jeffrey, P. D., & Randall, J. (2011) · InTech eBooks · doi:10.5772/18436 · Cited by 4 · see citing works

Environmental Influences on the Epigenome: Exposure- Associated DNA Methylation in Human Populations

Martin, E. M., & Fry, R. C. (2018) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-040617-014629 · Cited by 640 · see citing works

Air pollution and children’s health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter

Johnson, N. M., Hoffmann, A. R., Behlen, J. C., Lau, C., Pendleton, D., Harvey, N., Shore, R., Li, Y., Chen, J., Tian, Y., et al. (2021) · Environmental Health and Preventive Medicine · doi:10.1186/s12199-021-00995-5 · Cited by 339 · see citing works

DNA methylation dynamics in aging: how far are we from understanding the mechanisms?

Ciccarone, F., Tagliatesta, S., Caiafa, P., & Zampieri, M. (2017) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2017.12.002 · Cited by 184 · see citing works

Mosaicism for trisomy 21: A review

Papavassiliou, P., Charalsawadi, C., Rafferty, K. A., & Jackson‐Cook, C. K. (2014) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36861 · Cited by 166 · see citing works

Vulnerability of primitive human placental trophoblast to Zika virus

Sheridan, M. A., Yunusov, D., Balaraman, V., Alexenko, A. P., Yabe, S., Verjovski‐Almeida, S., Schust, D. J., Franz, A. W. E., Sadovsky, Y., Ezashi, T., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1616097114 · Cited by 164 · see citing works

Dosage compensation of the sex chromosomes and autosomes

Distèche, C. M. (2016) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2016.04.013 · Cited by 125 · see citing works

Prenatal epigenetics diets play protective roles against environmental pollution

Li, S., Chen, M., Li, Y., & Tollefsbol, T. O. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0659-4 · Cited by 128 · see citing works

Identification of a DNA methylation signature in blood cells from persons with Down Syndrome

Bacalini, M. G., Gentilini, D., Boattini, A., Giampieri, E., Pirazzini, C., Giuliani, C., Fontanesi, E., Scurti, M., Remondini, D., Capri, M., et al. (2014) · Aging · doi:10.18632/aging.100715 · Cited by 121 · see citing works

The Human Placental MethylomePreprint

Robinson, W. P., & Price, E. M. (2015) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a023044 · Cited by 102 · see citing works

Epigenetic dysregulation in the developing Down syndrome cortex

Hajj, N. E., Dittrich, M. T., Böck, J., Kraus, T. F. J., Nanda, I., Müller, T., Seidmann, L., Tralau, T., Galetzka, D., Schneider, E., et al. (2016) · Epigenetics · doi:10.1080/15592294.2016.1192736 · Cited by 90 · see citing works

Down syndrome: Neurobiological alterations and therapeutic targets

Vacca, R. A., Bawari, S., Valenti, D., Tewari, D., Nabavi, S. F., Shirooie, S., Sah, A. N., Volpicella, M., Braidy, N., & Nabavi, S. M. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.01.001 · Cited by 90 · see citing works

Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome

Jones, M. J., Farré, P., McEwen, L. M., MacIsaac, J. L., Watt, K., Neumann, S., Emberly, E. G., Cynader, M. S., Virji‐Babul, N., & Kobor, M. S. (2013) · BMC Medical Genomics · doi:10.1186/1755-8794-6-58 · Cited by 87 · see citing works

Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models

Mendióroz, M., Do, C., Jiang, X., Liu, C., Darbary, H. K., Lang, C. F., Lin, J. P., Thomas, A. C., Abu-Amero, S. N., Stanier, P., et al. (2015) · Genome biology · doi:10.1186/s13059-015-0827-6 · Cited by 85 · see citing works

Epigenetic dysregulation of protocadherins in human disease

Hajj, N. E., Dittrich, M. T., & Haaf, T. (2017) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2017.07.007 · Cited by 76 · see citing works

Epigenetics: The neglected key to minimize learning and memory deficits in Down syndrome

Dekker, A. D., Deyn, P. P. D., & Rots, M. G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.05.004 · Cited by 62 · see citing works

Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression

Lu, J., Mccarter, M., Lian, G., Esposito, G., Capoccia, E., Delli-Bovi, L. C., Hecht, J. L., & Sheen, V. L. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw043 · Cited by 61 · see citing works

A complex association between DNA methylation and gene expression in human placenta at first and third trimesters

Lim, Y. C., Li, J., Ni, Y., Liang, Q. H., Zhang, J., Yeo, G. S., Lyu, J., Jin, S., & Ding, C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181155 · Cited by 60 · see citing works

Epigenetic mechanisms of particulate matter exposure: air pollution and hazards on human health

Covarrubias, D. G., Ramírez‐Díaz, I., Guzmán-Linares, J., Limón, I. D., Manuel-Sánchez, D. M., Molina-Herrera, A., Coral-García, M. Á., Anastasio, E., Anaya‐Hernández, A., López‐Salazar, P., et al. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2023.1306600 · Cited by 62 · see citing works

Folic acid intervention during pregnancy alters DNA methylation, affecting neural target genes through two distinct mechanisms

Ondičová, M., Irwin, R. E., Thursby, S.-J., Hilman, L., Caffrey, A., Cassidy, T., McLaughlin, M., Lees‐Murdock, D. J., Ward, M., Murphy, M. M., et al. (2022) · Clinical Epigenetics · doi:10.1186/s13148-022-01282-y · Cited by 56 · see citing works

Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles

Laufer, B. I., Hwang, H., Jianu, J. M., Mordaunt, C. E., Korf, I. F., Hertz‐Picciotto, I., & LaSalle, J. M. (2020) · Human Molecular Genetics · doi:10.1093/hmg/ddaa218 · Cited by 51 · see citing works

DNA-Methylation Patterns in Trisomy 21 Using Cells from Monozygotic Twins

Sailani, M. R., Santoni, F. A., Letourneau, A., Borel, C., Makrythanasis, P., Hibaoui, Y., Popadin, K. Y., Bonilla, X., Guipponi, M., Gehrig, C., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135555 · Cited by 49 · see citing works

Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights

Laufer, B. I., Hwang, H., Ciernia, A. V., Mordaunt, C. E., & LaSalle, J. M. (2019) · Epigenetics · doi:10.1080/15592294.2019.1609867 · Cited by 47 · see citing works

Stem and progenitor cell dysfunction in human trisomies

Liu, B., Filippi, S. L., Roy, A., & Roberts, I. A. G. (2014) · EMBO Reports · doi:10.15252/embr.201439583 · Cited by 42 · see citing works

Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis

Lim, Y. C., Chia, S. Y., Jin, S., Han, W., Ding, C., & Sun, L. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2016.08.006 · Cited by 43 · see citing works

REST Is Not Resting: REST/NRSF in Health and Disease

Jin, L., Liu, Y., Wu, Y., Huang, Y., & Zhang, D. (2023) · Biomolecules · doi:10.3390/biom13101477 · Cited by 40 · see citing works

Targeting Mitochondrial Network Architecture in Down Syndrome and Aging

Mollo, N., Cicatiello, R., Aurilia, M., Scognamiglio, R., Genesio, R., Charalambous, M., Paladino, S., Conti, A. M. F., Nitsch, L., & Izzo, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093134 · Cited by 39 · see citing works

Aneuploidy and Gene Expression: Is there Dosage Compensation?

Kojima, S., & Cimini, D. (2019) · Epigenomics · doi:10.2217/epi-2019-0135 · Cited by 39 · see citing works

Detection strategies for methylated and hypermethylated DNA

Taleat, Z., Mathwig, K., Sudhölter, E. J. R., & Rassaei, L. (2015) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2014.11.013 · Cited by 34 · see citing works

DNA methylation changes in Down syndrome derived neural iPSCs uncover co-dysregulation of ZNF and HOX3 families of transcription factors

Laan, L., Klar, J., Sobol, M., Hoeber, J., Shahsavani, M., Kele, M., Fatima, A., Zakaria, M., Annerén, G., Falk, A., et al. (2020) · Clinical Epigenetics · doi:10.1186/s13148-019-0803-1 · Cited by 33 · see citing works

Widespread domain-like perturbations of DNA methylation in whole blood of Down syndrome neonates

Henneman, P., Bouman, A., Mul, A. N. P. M., Knegt, L. C., van der Kevie-Kersemaekers, A.-M. F., Zwaveling‐Soonawala, N., Meijers-Heijboer, H. E. J., van Trotsenburg, A. S. P., & Mannens, M. M. A. M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194938 · Cited by 32 · see citing works

Mouse-based genetic modeling and analysis of Down syndrome

Xing, Z., Li, Y., Pao, A., Bennett, A. S., Tycko, B., Mobley, W. C., & Yu, Y. E. (2016) · British Medical Bulletin · doi:10.1093/bmb/ldw040 · Cited by 30 · see citing works

Trisomy 21 and Assisted Reproductive Technologies: A review

Sánchez-Pavón, E., Mendoza, H., & García-Ferreyra, J. (2021) · JBRA · doi:10.5935/1518-0557.20210047 · Cited by 29 · see citing works

Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models

Yu, Y. E., Xing, Z., Do, C., Pao, A., Lee, E. J., Krinsky‐McHale, S. J., Silverman, W. P., Schupf, N., & Tycko, B. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2019.09.002 · Cited by 27 · see citing works

DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project

Ciccarone, F., Valentini, E., Malavolta, M., Zampieri, M., Bacalini, M. G., Calabrese, R., Guastafierro, T., Reale, A., Franceschi, C., Capri, M., et al. (2017) · The Journals of Gerontology Series A · doi:10.1093/gerona/glx198 · Cited by 25 · see citing works

Dysfunctions of mitochondria in close association with strong perturbation of long noncoding RNAs expression in down syndrome

Qiu, J., Liu, Y.-N., Ren, Z., & Yan, J. (2017) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2017.09.017 · Cited by 23 · see citing works

Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing

Gordevičius, J., Narmontė, M., Gibas, P., Kvederavičiūtė, K., Tomkutė, V., Paluoja, P., Krjutškov, K., Salumets, A., & Kriukienė, E. (2020) · Clinical Epigenetics · doi:10.1186/s13148-020-00938-x · Cited by 23 · see citing works

MTHFR promoter hypermethylation may lead to congenital heart defects in Down syndrome

Asim, A., Agarwal, S., Panigrahi, I., Saiyed, N., & Bakshi, S. R. (2017) · Intractable & Rare Diseases Research · doi:10.5582/irdr.2017.01068 · Cited by 22 · see citing works

DSCR1‐mediated TET1 splicing regulates miR‐124 expression to control adult hippocampal neurogenesis

Choi, C., Kim, T., Chang, K. T., & Min, K. (2019) · The EMBO Journal · doi:10.15252/embj.2018101293 · Cited by 21 · see citing works

Microarray-Based Analysis of Methylation of 1st Trimester Trisomic Placentas from Down Syndrome, Edwards Syndrome and Patau Syndrome

Hatt, L., Aagaard, M. M., Bach, C. C., Graakjær, J., Sommer, S., Agerholm, I., Kølvraa, S., & Bojesen, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160319 · Cited by 20 · see citing works

Rethinking intellectual disability from neuro- to astro-pathology.

Fernández-Blanco, Á., & Dierssen, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239039 · Cited by 19 · see citing works

Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders

Toma, I. D., Manubens-Gil, L., Ossowski, S., & Dierssen, M. (2016) · Neural Plasticity · doi:10.1155/2016/4235898 · Cited by 19 · see citing works

Down Syndrome, Ageing and Epigenetics

Gensous, N., Franceschi, C., Salvioli, S., Garagnani, P., & Bacalini, M. G. (2019) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-3681-2_7 · Cited by 19 · see citing works

Aneuploidy and DNA Methylation as Mirrored Features of Early Human Embryo Development

Tolmacheva, E. N., Vasilyev, S. А., & Лебедев, И. Н. (2020) · Genes · doi:10.3390/genes11091084 · Cited by 20 · see citing works

Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & Yin, J. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-02053-3 · Cited by 19 · see citing works

Placental development and function in trisomy 21 and mouse models of Down syndrome: Clues for studying mechanisms underlying atypical development

Adams, A. D., Guedj, F., & Bianchi, D. W. (2019) · Placenta · doi:10.1016/j.placenta.2019.10.002 · Cited by 18 · see citing works

Genes uniquely expressed in human growth plate chondrocytes uncover a distinct regulatory network

Li, B., Balasubramanian, K., Krakow, D., & Cohn, D. H. (2017) · BMC Genomics · doi:10.1186/s12864-017-4378-y · Cited by 18 · see citing works

Transcriptome-wide analysis of the SCNT bovine abnormal placenta during mid- to late gestation

Gao, G., Wang, S., Zhang, J., Su, G., Zheng, Z., Bai, C., Yang, L., Wei, Z., Wang, X., Liu, X., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-56566-w · Cited by 17 · see citing works

Comparative Assessment of DNA Methylation Patterns Between Reduced Representation Bisulfite Sequencing and Sequenom Epityper Methylation Analysis

Chatterjee, A., Macaulay, E. C., Ahn, A., Ludgate, J. L., Stockwell, P. A., Weeks, R. J., Parry, M. F., Foster, T. J., Knarston, I. M., Eccles, M. R., et al. (2017) · Epigenomics · doi:10.2217/epi-2016-0176 · Cited by 17 · see citing works

Mercury Concentration, DNA Methylation, and Mitochondrial DNA Damage in Olive Ridley Sea Turtle Embryos With Schistosomus Reflexus Syndrome

Martín-del-Campo, R., Bárcenas-Ibarra, A., Lund, G., Rodríguez-Ríos, D., Yong-Villalobos, L., García-Hernández, J., & García-Gasca, A. (2019) · Veterinary Pathology-Supplement · doi:10.1177/0300985819868649 · Cited by 14 · see citing works

The Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis

Papageorgiou, E. A., Koumbaris, G., Kypri, E., Hadjidaniel, M. D., & Patsalis, P. C. (2014) · Genes · doi:10.3390/genes5020310 · Cited by 15 · see citing works

Epigenome-wide base-resolution profiling of DNA methylation in chorionic villi of fetuses with Down syndrome by methyl-capture sequencing

Lim, J. H., Kang, Y.-J., Lee, B. Y., Han, Y. J., Chung, J. H., Kim, M. Y., Kim, M. H., Kim, J., Cho, Y.-H., & Ryu, H. M. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0756-4 · Cited by 15 · see citing works

Comprehensive investigation of DNA methylation and gene expression in trisomy 21 placenta

Lim, J. H., Kim, S. Y., Han, J. Y., Kim, M. Y., Park, S. Y., & Ryu, H. M. (2016) · Placenta · doi:10.1016/j.placenta.2016.03.012 · Cited by 15 · see citing works

DNA Methylation Alterations in Blood Cells of Toddlers with Down Syndrome

Naumova, O. Y., Lipschutz, R. S., Rychkov, S. Y., Zhukova, O. V., & Grigorenko, E. L. (2021) · Genes · doi:10.3390/genes12081115 · Cited by 15 · see citing works

Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature

Laufer, B. I., Gomez, J. A., Jianu, J. M., & LaSalle, J. M. (2021) · Epigenetics & Chromatin · doi:10.1186/s13072-021-00387-7 · Cited by 15 · see citing works

LINE-1 retrotransposon methylation in chorionic villi of first trimester miscarriages with aneuploidy

Vasilyev, S. А., Tolmacheva, E. N., Vasilyeva, O. Y., Markov, A., Жигалина, Д. И., Zatula, L. A., Lee, V. A., Сергеевна, С. Е., Sazhenova, E. A., Tv, N., et al. (2020) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-020-02003-1 · Cited by 11 · see citing works

Down syndrome: from the age of characterization to the era of curative approach

Ganguly, B. B., & Kadam, N. N. (2016) · The Nucleus · doi:10.1007/s13237-016-0187-y · Cited by 11 · see citing works

Human trophoblasts are primarily distinguished from somatic cells by differences in the pattern rather than the degree of global CpG methylation

Gamage, T. K. J. B., Schierding, W. S., Tsai, P., Ludgate, J. L., Chamley, L., Weeks, R. J., Macaulay, E. C., & James, J. L. (2018) · Biology Open · doi:10.1242/bio.034884 · Cited by 10 · see citing works

Detecting methylation signatures in neurodegenerative disease by density-based clustering of applications with reducing noise

Mallik, S., & Zhao, Z. (2020) · Scientific Reports · doi:10.1038/s41598-020-78463-3 · Cited by 10 · see citing works

The Epigenetic Landscape of Aneuploidy: Constitutional Mosaicism Leading the Way?

Davidsson, J. (2014) · Epigenomics · doi:10.2217/epi.13.78 · Cited by 10 · see citing works

Integrated microRNA and protein expression analysis reveals novel microRNA regulation of targets in fetal down syndrome

Hua, L., Sui, W., Li, W., Tan, Q., Chen, J., Lin, X., Guo, H., Ou, M., Xue, W., Zhang, R., et al. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5775 · Cited by 10 · see citing works

Comparative genome-wide DNA methylation analysis in myocardial tissue from donors with and without Down syndrome

Cejas, R. B., Wang, J., Blair, R. H., Liu, S., & Blanco, J. G. (2020) · Gene · doi:10.1016/j.gene.2020.145099 · Cited by 8 · see citing works

Global DNA Methylation Levels Viz-a-Viz Genetic and Biochemical Variations in One Carbon Metabolic Pathway: An Exploratory Study from North India

Chaudhary, V., Bhattacharjee, D., Devi, N. K., & Saraswathy, K. N. (2024) · Biochemical Genetics · doi:10.1007/s10528-023-10659-4 · Cited by 7 · see citing works

PRDM8 internal promoter hyperhydroxymethylation correlates with increased expression of the corresponding transcript in Down syndrome

Lu, Z., Liu, Y., Ren, Z., & Yan, J. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5375 · Cited by 7 · see citing works

Epigenetics and Down syndrome

González-Molina, L. A., Dekker, A. D., Deyn, P. P. D., Dolga, A. M., & Rots, M. G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18516-8.00014-4 · Cited by 6 · see citing works

Intricacies of aging and Down syndrome

Kozlov, G., Franceschi, C., & Vedunova, M. V. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105794 · Cited by 6 · see citing works

Epigenetics of Down Syndrome

Maheshwari, A., & Singh, S. (2024) · Newborn · doi:10.5005/jp-journals-11002-0112 · Cited by 6 · see citing works

Alterations of epigenetic landscape in Down syndrome carrying pregnancies: A systematic review of case-control studies

Karimzadeh, M. R., Ehtesham, N., Mortazavi, D., Azhdari, S., Mosallaei, M., & Nezamnia, M. (2021) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2021.06.027 · Cited by 6 · see citing works

Placental biomarkers for the prediction of neurodevelopmental disorders

Patel, P. B., Ku, J., Uzoaru, I., & Goldstein, J. A. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1663960 · Cited by 5 · see citing works

Delayed atorvastatin delivery promotes recovery after experimental spinal cord injury

Buchl, S. C., Kim, H. N., Hur, B., Simon, W. L., Langley, M. R., Sung, J., & Scarisbrick, I. A. (2025) · Neurotherapeutics · doi:10.1016/j.neurot.2024.e00517 · Cited by 5 · see citing works

DNA methylation alterations in the genome of a toddler with cri‐du‐chat syndrome

Naumova, O. Y., Rychkov, S. Y., Kuznetzova, T. V., Odintsova, V. V., Kornilov, S. A., & Grigorenko, E. L. (2017) · Clinical Case Reports · doi:10.1002/ccr3.1274 · Cited by 5 · see citing works

Integrated analysis of DNA methylation and RNA-sequencing data in Down syndrome

Zhang, J., Zhou, W., Liu, Y., & Li, N. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5778 · Cited by 4 · see citing works

Epigenetic Control of Hyperuricemia and Gout by Gene Writer DNMT1 and RNA Editor ADAR1: Mechanism of Gout and Amyloid Dissolution in Down Syndrome

Tyagi, S. C., Smolenkova, I. A., Zheng, Y., & Singh, M. (2025) · Biochemical Genetics · doi:10.1007/s10528-025-11038-x · Cited by 3 · see citing works

Genetic interactions and co-operating effects of non-HSA21 genes on the phenotypic variability in Down syndrome

Ganguly, B. B., & Kadam, N. N. (2024) · Gene Reports · doi:10.1016/j.genrep.2024.102106 · Cited by 3 · see citing works

The Dynamic Roles of Repressor Element 1-Silencing Transcription Factor (REST): A Double-Edged Sword in Neural Health and Disease

Eva, T. A., Shenoy, A., Gupta, V. B., Palanivel, V., Salkar, A., Nasab, S. N., Chitranshi, N., Mirzaei, M., You, Y., Graham, S. L., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05304-7 · Cited by 2 · see citing works

Downstream Assays for Variant Resolution: Epigenetics, RNA Sequnncing, and Metabolomics.

Shayota, B. J. (2023) · The Pediatric clinics of North America · doi:10.1016/j.pcl.2023.05.006 · Cited by 4 · see citing works

Identification of a thymus microRNA‑mRNA regulatory network in Down syndrome

Chai, M., Su, L., Hao, X., Zhang, M., Zheng, L., Bi, J., Han, X., & Gao, C. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10433 · Cited by 2 · see citing works

Higher-Order Unfolding of Peri/Centric Satellite Heterochromatin is an Early and Consistent Event in Cell Senescence: A Dissertation

Swanson, E. C. (2014) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/m2k30f · Cited by 1 · see citing works

Hippocampal miR-124 mediates depression-like behavior via the USP14/REST signaling pathway in CRS- and CUMS-induced mouse models

Xie, H., Xue, Y., Deng, R., Chen, L., Wang, Y., Xu, J., Liu, H., Li, X., Cui, W., & Zhang, J. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.120841 · Cited by 1 · see citing works

Multi-omics investigation of thyroid development and dysfunction in down syndrome

Lauffer, P., Zwaveling‐Soonawala, N., Yim, A. Y. F. L., van der Laan, L., van Zelderen‐Bhola, S. L., Venema, A., Mul, A. N. P. M., Bugiani, M., Rijnstra, E. S.-V., Gunst, Q. D., et al. (2026) · Human Molecular Genetics · doi:10.1093/hmg/ddag005 · Cited by 1 · see citing works

Transforming blood-derived episignatures into cell-type-agnostic classifiers: A shortcut to prenatal episignatures

Reko, N., Torabi‐Marashi, A., Kallurkar, P. S., Goodman, S. J., Awamleh, Z., Turinsky, A. L., Grafodatskaya, D., Russell, B. E., Chong, K., Ko, J. M., et al. (2026) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2026.06.017 · Cited by 1 · see citing works

Epigenetics and Down syndrome

Dekker, A. D., Deyn, P. P. D., & Rots, M. G. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800226-1.00009-5 · Cited by 1 · see citing works

Red cell folate status among a subset of Canadian children with Down Syndrome post‐fortification

Jory, J. (2022) · Journal of Intellectual Disability Research · doi:10.1111/jir.12925

MicroRNAs and epigenetic signatures in Down syndrome

Ganguly, B. B. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90456-8.00011-9

Gene-dosage imbalance due to trisomic HSA21 and genotype–phenotype association in Down syndrome

Ganguly, B. B. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90456-8.00005-3

Regulation of fetal brain development in short versus long lived mice

Islam, M. (2022) · doi:10.32469/10355/94012

Increased methylation levels of the MTHFR gene promoter in Down syndrome

Majstorović, D., Stoccoro, A., Barišić, A., Buretić‐Tomljanović, A., Giangreco, M., Nicolì, V., Coppedè, F., & Vraneković, J. (2025) · Epigenomics · doi:10.1080/17501911.2025.2563501

Analysis of mitochondrial D-loop region methylation and copy number in peripheral blood DNA of Down syndrome individuals including newborns with and without congenital heart defects

Stoccoro, A., Majstorović, D., Sebastiani, V., Barišić, A., Vraneković, J., & Coppedè, F. (2025) · Epigenetics Communications · doi:10.1186/s43682-025-00039-x

Changed expression of placental transporters and disrupted epigenetic patterns in a rat model of schizophrenia

Szatmári, P., Seres, A. B., Sztojkov‐Ivanov, A., Kékesi, G., Horváth, G., & Ducza, E. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1673124

Additional file 7 of Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & Yin, J. (2020) · Figshare · doi:10.6084/m9.figshare.13468001

Additional file 2 of Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing

Gordevičius, J., Narmontė, M., Gibas, P., Kvederavičiūtė, K., Tomkutė, V., Paluoja, P., Krjutškov, K., Salumets, A., & Kriukienė, E. (2020) · Figshare · doi:10.6084/m9.figshare.13120830

Additional file 2 of Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & Yin, J. (2020) · Figshare · doi:10.6084/m9.figshare.13467989

Additional file 6 of Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & 尹靖东 (2020) · Figshare · doi:10.6084/m9.figshare.13467999

Additional file 1 of Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & Yin, J. (2020) · Figshare · doi:10.6084/m9.figshare.13467985

Additional file 3 of Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & 尹靖东 (2020) · Figshare · doi:10.6084/m9.figshare.13467991

Additional file 2 of Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature

Laufer, B. I., Gomez, J. A., Jianu, J. M., & LaSalle, J. M. (2021) · Figshare · doi:10.6084/m9.figshare.14189577

Additional file 4 of Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & 尹靖东 (2020) · Figshare · doi:10.6084/m9.figshare.13467995

Additional file 1 of Air pollution and children’s health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter

Johnson, N. M., Hoffmann, A. R., Behlen, J. C., Lau, C. H., Pendleton, D., Harvey, N., Shore, R. A., Li, Y., Chen, J., Tian, Y., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14966363

Additional file 5 of Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

Zhang, X., Sun, W., He, L., Wang, L., Qiu, K., & 尹靖东 (2020) · Figshare · doi:10.6084/m9.figshare.13467997

Global DNA hypermethylation in down syndrome placenta. PLoS Genet

Jin, S., Lee, Y. K., Lim, Y. C., Zheng, Z., Lin, X. M., Ng, D. P. Y., Holbrook, J. D., Law, H. Y., Kwek, K. Y. C., Yeo, G. S. H., et al. (2016)

Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights

Laufer, B. I., Hwang, H., Ciernia, A. V., Mordaunt, C. E., & LaSalle, J. M. (2019) · Epigenetics · doi:10.1080/15592294.2019.1609867 · Cited by 47 · see citing works

Epigenetic dysregulation in the developing Down syndrome cortex

Hajj, N. E., Dittrich, M. T., Böck, J., Kraus, T. F. J., Nanda, I., Müller, T., Seidmann, L., Tralau, T., Galetzka, D., Schneider, E., et al. (2016) · Epigenetics · doi:10.1080/15592294.2016.1192736 · Cited by 90 · see citing works

Identification of a DNA methylation siganture in blood cells from persons with Down Syndrome.

Bacalini, M. G., Gentilini, D., Boattini, A., Giampieri, E., Pirazzini, C., Giuliani, C., FONTANESI, E., Scurti, M., Remondini, D., CAPRI, M., et al. (2015) · Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna)

Epigenome-wide base-resolution profiling of DNA methylation in chorionic villi of fetuses with Down syndrome by methyl-capture sequencing

Lim, J. H., Kang, Y.-J., Lee, B. Y., Han, Y. J., Chung, J. H., Kim, M. Y., Kim, M. H., Kim, J., Cho, Y.-H., & Ryu, H. M. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0756-4 · Cited by 15 · see citing works