Genetic compensation: A phenomenon in search of mechanisms

Network biology: understanding the cell's functional organization

Barabási, A.-L., & Oltvai, Z. N. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1272 · Cited by 7,903

Untitled work

(2008) · doi:10.1038/nrg2290 · Cited by 5,199

Functional profiling of the Saccharomyces cerevisiae genome

Giaever, G., Chu, A. M., Ni, L., Connelly, C., Riles, L., Véronneau, S., Dow, S., Lucau-Danila, A., Anderson, K., André, B., et al. (2002) · Nature · doi:10.1038/nature00935 · Cited by 4,316

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

LYON, M. F. (1961) · Nature · doi:10.1038/190372a0 · Cited by 3,978

The Transcriptional Landscape of the Mammalian Genome

Carninci, P., Kasukawa, T., Katayama, S., Gough, J., Frith, M. C., Maeda, N., Oyama, R., Ravasi, T., Lenhard, B., Wells, C. A., et al. (2005) · Science · doi:10.1126/science.1112014 · Cited by 3,492

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

Raj, A., & van Oudenaarden, A. (2008) · Cell · doi:10.1016/j.cell.2008.09.050 · Cited by 2,593

Antisense Transcription in the Mammalian Transcriptome

Katayama, S., Tomaru, Y., Kasukawa, T., Waki, K., Nakanishi, M., Nakamura, M., Nishida, H., Yap, C.-S., Suzuki, M., Kawai, J., et al. (2005) · Science · doi:10.1126/science.1112009 · Cited by 1,699

MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

Pasquinelli, A. E. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3162 · Cited by 1,642

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

Manley, G. T., Fujimura, M., Ma, T., Noshita, N., Filiz, F., Bollen, A. W., Chan, P. H., & Verkman, A. S. (2000) · Nature Medicine · doi:10.1038/72256 · Cited by 1,501

RNA‐binding proteins and post‐transcriptional gene regulation

Glisovic, T., Bachorik, J. L., Yong, J., & Dreyfuss, G. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.03.004 · Cited by 1,398

Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity

Balan, I. S., Warnock, K. T., Puché, A. C., Gondré‐Lewis, M. C., & Aurelian, L. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.11.008 · Cited by 24

Genome plasticity in response to stress in Tetrahymena thermophila : selective and reversible chromosome amplification and paralogous expansion of metallothionein genes

de Francisco, P., Martín‐González, A., Turkewitz, A. P., & Gutiérrez, J. C. (2018) · Environmental Microbiology · doi:10.1111/1462-2920.14251 · Cited by 24

Conserved role of matrix metalloproteases 2 and 9 in promoting the migration of neural crest cells in avian and mammalian embryos

Kalev‐Altman, R., Hanael, E., Zelinger, E., Blum, M., Ornan, E. M., & Sela‐Donenfeld, D. (2020) · The FASEB Journal · doi:10.1096/fj.201901217rr · Cited by 24

Extracellular Vesicles in Pathophysiology: A Prudent Target That Requires Careful Consideration

Shahi, S. K., Kang, T., & Fonseka, P. (2024) · Cells · doi:10.3390/cells13090754 · Cited by 26

Ammonia excretion by the fish gill: discoveries and ideas that shaped our current understanding

Zimmer, A. M. (2024) · Journal of Comparative Physiology B · doi:10.1007/s00360-024-01561-5 · Cited by 23

Combined gene essentiality scoring improves the prediction of cancer dependency maps

Wang, W., Malyutina, A., Pessia, A., Saarela, J., Heckman, C. A., & Tang, J. P. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.10.051 · Cited by 23

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells

Arboit, A., Reboreda, A., & Yoshida, M. (2020) · Cells · doi:10.3390/cells9020365 · Cited by 25

Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform

Colón-Rodríguez, A., Uribe‐Salazar, J. M., Weyenberg, K., Sriram, A., Quezada, A., Kaya, G., Jao, E., Radke, B., Lein, P. J., & Dennis, M. Y. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.586296 · Cited by 23

Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis

Xiao, L., Fan, D., Qi, H., Cong, Y., & Du, Z. (2022) · Cell Systems · doi:10.1016/j.cels.2022.07.001 · Cited by 24

Characterization of Two-Component System CitB Family in Salmonella Pullorum

Kang, X., Zhou, X., Tang, Y., Jiang, Z., Chen, J., Mohsin, M., & Yue, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710201 · Cited by 23

Specific detection and deletion of the sigma‐1 receptor widely expressed in neurons and glial cells in vivo

Liu, Q., Guo, Q., Fang, L., Yao, H., Scheller, A., Kirchhoff, F., & Huang, W. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15693 · Cited by 23

Repressive ZINC FINGER OF ARABIDOPSIS THALIANA proteins promote programmed cell death in the Arabidopsis columella root cap

Feng, Q., Cubría-Radío, M., Vavrdová, T., Winter, F. D., Schilling, N., Huysmans, M., Nanda, A. K., Melnyk, C. W., & Nowack, M. K. (2023) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiad130 · Cited by 23

Zebrafish Models of Rare Hereditary Pediatric Diseases

Varga, M., Ralbovszki, D. M., Balogh, E., Hamar, R., Keszthelyi, M., & Tory, K. (2018) · Diseases · doi:10.3390/diseases6020043 · Cited by 26

An improved SNAP-ADAR tool enables efficient RNA base editing to interfere with post-translational protein modification

Kumar, K. D. K., Singh, S., Schmelzle, S. M., Vogel, P., Fruhner, C., Hanswillemenke, A., Brun, A., Wettengel, J., Füll, Y., Funk, L.-M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50395-w · Cited by 24

IL-33/ST2 induces macrophage-dependent ROS production and TRPA1 activation that mediate pain-like responses by skin incision in mice

Xu, R., Pan, Y., Zheng, K., Chen, M., Yin, C., Hu, Q., Wang, J., Yu, Q., Li, P., Tai, Y., et al. (2024) · Theranostics · doi:10.7150/thno.97856 · Cited by 23

BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila

Ueberschär, M., Wang, H., Zhang, C., Kondo, S., Aoki, T., Schedl, P. D., Lai, E. C., Wen, J., & Dai, Q. (2019) · Nature Communications · doi:10.1038/s41467-019-13558-8 · Cited by 22

Drosophila Activin signaling promotes muscle growth through InR/dTORC1 dependent and independent processes

Kim, M.-J., & O’Connor, M. B. (2020) · Development · doi:10.1242/dev.190868 · Cited by 21

Zebrafish Vascular Mural Cell Biology: Recent Advances, Development, and Functions

Ando, K., Ishii, T., & Fukuhara, S. (2021) · Life · doi:10.3390/life11101041 · Cited by 22

Beyond Mendelian Inheritance: Genetic Buffering and Phenotype Variability

Rossi, A., & Kontarakis, Z. (2021) · Phenomics · doi:10.1007/s43657-021-00030-1 · Cited by 23

Non-Coding RNAs Associated With Prader-Willi Syndrome Regulate Transcription of Neurodevelopmental Genes in Human Induced Pluripotent Stem Cells

Śledziowska, M., Winczura, K., Jones, M., Almaghrabi, R. O. M., Mischo, H. E., Hebenstreit, D., García, P., & Grzechnik, P. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddac228 · Cited by 22

Soybean hypocotyl elongation is regulated by a MYB33 ‐ SWEET11 /21‐ GA2ox8c module involving long‐distance sucrose transport

Su, T., Liu, H., Wu, Y.-C., Wang, J., He, F., Li, H., Li, S., Wang, L., Li, L., Cao, J., et al. (2024) · Plant Biotechnology Journal · doi:10.1111/pbi.14409 · Cited by 22

Setting up for gastrulation in zebrafish

Marlow, F. L. (2020) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2019.08.002 · Cited by 21

Amhr2-Cre–Mediated Global Tspo Knockout

Fan, J., Campioli, E., Sottas, C. M., Zirkin, B. R., & Papadopoulos, V. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa001 · Cited by 23

Global gene expression changes induced by knockout of a protease gene cluster in Helicoverpa armigera with CRISPR/Cas9

Wang, M., Zhang, S., Shi, Y., Yang, Y., & Wu, Y. (2020) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2020.104023 · Cited by 22

Nrf2 Regulates Basal Glutathione Production in Astrocytes

He, J., & Hewett, S. J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26020687 · Cited by 25

Two paralogous znf143 genes in zebrafish encode transcriptional activator proteins with similar functions but expressed at different levels during early development

Huning, L., & Kunkel, G. R. (2020) · BMC Molecular and Cell Biology · doi:10.1186/s12860-020-0247-7 · Cited by 21

The Rhesus glycoprotein Rhcgb is expendable for ammonia excretion and Na+ uptake in zebrafish (Danio rerio)

Zimmer, A. M., & Perry, S. F. (2020) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2020.110722 · Cited by 21

Orexin deficiency affects sociability and the acquisition, expression, and extinction of conditioned social fear

Faesel, N., Kolodziejczyk, M. H., Koch, M., & Fendt, M. (2020) · Brain Research · doi:10.1016/j.brainres.2020.147199 · Cited by 23

Dictyostelium discoideum as a Model for Investigating Neurodegenerative Diseases

Haver, H. N., & Scaglione, K. M. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.759532 · Cited by 20

Loss of HOXA10 causes endometrial hyperplasia progressing to endometrial cancer

Mishra, A., Ganguli, N., Majumdar, S. S., & Modi, D. N. (2022) · Journal of Molecular Endocrinology · doi:10.1530/jme-22-0051 · Cited by 21

L-Lactate Treatment at 24 h and 48 h after Acute Experimental Stroke Is Neuroprotective via Activation of the L-Lactate Receptor HCA1

Geiseler, S. J., Hadzic, A., Lambertus, M., Forbord, K. M., Sajedi, G., Liesz, A., & Morland, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021232 · Cited by 20

CRISPR-Cas9 mediated dsRNase knockout improves RNAi efficiency in the fall armyworm

Koo, J., Zhu, G., & Palli, S. R. (2024) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2024.105839 · Cited by 21

Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like behaviour and related brain functional activity

Moreno‐Fernández, R. D., Nieto-Quero, A., Gómez-Salas, F. J., Chun, J. J. M., Estivill‐Torrús, G., de Fonseca, F. R., Santín, L. J., Pérez‐Martín, M., & Pedraza, C. (2018) · Disease Models & Mechanisms · doi:10.1242/dmm.035519 · Cited by 22

CRISPR/Cas9-mediated genome editing in sea urchins

Lin, C.-Y., Oulhen, N., Wessel, G. M., & Su, Y. (2018) · Methods in cell biology · doi:10.1016/bs.mcb.2018.10.004 · Cited by 21

Mitochondrial DNA Damage Does Not Determine C. elegans Lifespan

Ng, L. F., Ng, L. T., van Breugel, M., Halliwell, B. B., & Gruber, J. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00311 · Cited by 22

Proteasome activator PA200 regulates myofibroblast differentiation

Welk, V., Meul, T., Lukas, C., Kammerl, I. E., Mulay, S. R., Schamberger, A. C., Semren, N., Fernandez, I. E., Anders, H., Günther, A., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-51665-0 · Cited by 21

Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish

Grimes, D. T., Patterson, V. L., Luna-Arvizu, G., Schottenfeld-Roames, J., Irons, Z. H., & Burdine, R. D. (2019) · Developmental Biology · doi:10.1016/j.ydbio.2019.11.012 · Cited by 21

An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement

Poplawski, S. G., Garbett, K. A., McMahan, R. L., Kordasiewicz, H. B., Zhao, H. T., Kennedy, A. J., Goleva, S. B., Sanders, T. H., Motley, S. T., Swayze, E. E., et al. (2020) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2020.01.027 · Cited by 21

The epilepsy and intellectual disability-associated protein TBC1D24 regulates the maintenance of excitatory synapses and animal behaviors

Lin, L.-F., Lyu, Q., Kwan, P., Zhao, J., Fan, R., Chai, A., Lai, C. S. W., Chan, Y., Shen, X., & Lai, K. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1008587 · Cited by 22

Identification of the Risk Genes Associated With Vulnerability to Addiction: Major Findings From Transgenic Animals

Jordan, C. J., & Xi, Z.-X. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.811192 · Cited by 20

Transcriptional adaptation: where mRNA decay meets genetic compensation

Falcucci, L., Juvik, B., & Stainier, D. Y. R. (2025) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2025.102369 · Cited by 20

Lateral hypothalamic fast-spiking parvalbumin neurons modulate nociception through connections in the periaqueductal gray area

Siemian, J. N., Borja, C. B., Sarsfield, S., Kisner, A., & Aponte, Y. (2019) · Scientific Reports · doi:10.1038/s41598-019-48537-y · Cited by 19

Overexpression approaches to advance understanding of Candida albicans

Rai, L. S., van Wijlick, L., Chauvel, M., d’Enfert, C., Legrand, M., & Bachellier‐Bassi, S. (2021) · Molecular Microbiology · doi:10.1111/mmi.14818 · Cited by 17

Transcriptome-Based Identification and Functional Characterization of NAC Transcription Factors Responsive to Drought Stress in Capsicum annuum L.

Borràs, D., Barchi, L., Schulz, K., Moglia, A., Acquadro, A., Kamranfar, I., Balazadeh, S., & Lanteri, S. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.743902 · Cited by 20

History and Classification of CRISPR/Cas System

Khan, Z., Ali, Z., Khan, A. A., Sattar, T., Zeshan, A., Saboor, T., & Binyamin, B. (2022) · Springer eBooks · doi:10.1007/978-981-16-6305-5_2 · Cited by 21

Suppression of mitochondrial alternative oxidase can result in upregulation of the ROS scavenging network: some possible mechanisms underlying the compensation effect

Владимировна, Г. Е. (2022) · Plant Biology · doi:10.1111/plb.13477 · Cited by 20

Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution

Sodir, N. M., Pellegrinet, L., Kortlever, R. M., Campos, T., Kwon, Y.-W., Kim, S., Garcia, D. A., Perfetto, A., Anastasiou, P., Swigart, L. B., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-34079-x · Cited by 18

Unraveling the genetic architecture of congenital vertebral malformation with reference to the developing spine

Zhao, S., Zhao, H., Zhao, L., Cheng, X., Zheng, Z., Wu, M., Wen, W., Wang, S., Zhou, Z., Xie, H., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45442-5 · Cited by 20

Allele-specific transcriptional effects of subclonal copy number alterations enable genotype-phenotype mapping in cancer cells

Shi, H., Williams, M. J., Satas, G., Weiner, A. C., McPherson, A., & Shah, S. P. (2024) · Nature Communications · doi:10.1038/s41467-024-46710-0 · Cited by 19

Ultramicronized N-palmitoylethanolamine associated with analgesics: Effects against persistent pain

Nobili, S., Micheli, L., Lucarini, E., Toti, A., Ghelardini, C., & Mannelli, L. D. C. (2024) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2024.108649 · Cited by 22

Zebrafish models of candidate human epilepsy-associated genes provide evidence of hyperexcitability

LaCoursiere, C. M., Ullmann, J. F. P., Koh, H. Y., Turner, L. H., Baker, C. M., Robens, B. K., Shao, W., Rotenberg, A., McGraw, C. M., & Poduri, A. (2024) · iScience · doi:10.1016/j.isci.2024.110172 · Cited by 20

Premature Termination Codon-Bearing mRNA Mediates Genetic Compensation Response

Ma, Z., & Chen, J. (2020) · Zebrafish · doi:10.1089/zeb.2019.1824 · Cited by 19

TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro

Smeriglio, P., Grandi, F. C., Taylor, S. E. B., Zalc, A., & Bhutani, N. (2020) · JBMR Plus · doi:10.1002/jbm4.10383 · Cited by 20

setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals

Liu, D.-J., Zhang, F., Chen, Y., Jin, Y., Zhang, Y., Chen, S.-B., Xie, Y., Huang, Q., Zhao, W., Wang, L., et al. (2020) · Cell Discovery · doi:10.1038/s41421-020-00203-8 · Cited by 19

ER-to-Golgi transport and SEC23-dependent COPII vesicles regulate T cell alloimmunity

Kim, S., Khoriaty, R. N., Li, L., McClune, M., Kalfa, T. A., Wu, J. J., Peltier, D., Fujiwara, H., Sun, Y., Oravecz-Wilson, K. I., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci136574 · Cited by 18

The good, the bad, and the ugly: Evolutionary and pathological aspects of gene dosage alterations

Basilicata, M. F., & Valsecchi, C. I. K. (2021) · PLoS Genetics · doi:10.1371/journal.pgen.1009906 · Cited by 19

Genome Functional Analysis of the Psychrotrophic Lignin-Degrading Bacterium Arthrobacter sp. C2 and the Role of DyP in Catalyzing Lignin Degradation

Jiang, C., Yan, H., Shen, X., Zhang, Y., Wang, Y., Sun, S., Jiang, H., Zang, H., Zhao, X., Hou, N., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.921549 · Cited by 19

Intrahippocampal Inoculation of Aβ1–42 Peptide in Rat as a Model of Alzheimer’s Disease Identified MicroRNA-146a-5p as Blood Marker with Anti-Inflammatory Function in Astrocyte Cells

Aquino, R., de Concini, V., Dhénain, M., Lam, S., Gosset, D., Baquedano, L., Forero, M. G., Menuet, A., Baril, P., & Pichon, C. (2023) · Cells · doi:10.3390/cells12050694 · Cited by 21

A forebrain undivided: Unleashing model organisms to solve the mysteries of holoprosencephaly

Grinblat, Y., & Lipinski, R. J. (2019) · Developmental Dynamics · doi:10.1002/dvdy.41 · Cited by 21

Reply to: Ptbp1 deletion does not induce astrocyte-to-neuron conversion

Hao, Y., Hu, J., Xue, Y., Dowdy, S. F., Mobley, W. C., Qian, H., & Fu, X. (2023) · Nature · doi:10.1038/s41586-023-06067-8 · Cited by 18

TBC1D10C is a cytoskeletal functional linker that modulates cell spreading and phagocytosis in macrophages

Villagómez, F. R., Díaz‐Valencia, J. D., Ovalle‐García, E., Antillón, A., Ortega‐Blake, I., Romero‐Ramírez, H., Cerna-Cortés, J. F., Rosales-Reyes, R., Santos‐Argumedo, L., & Patiño‐López, G. (2021) · Scientific Reports · doi:10.1038/s41598-021-00450-z · Cited by 18

A review on the impacts of nanomaterials on neuromodulation and neurological dysfunction using a zebrafish animal model

Cho, H.-J., Lee, W. S., Jeong, J., & Lee, J.-S. (2022) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2022.109428 · Cited by 21

Modeling Neuronal Diseases in Zebrafish in the Era of CRISPR

Espino-Saldaña, Á. E., Rodríguez-Ortiz, R., Pereida‐Jaramillo, E., & Martínez‐Torres, A. (2019) · Current Neuropharmacology · doi:10.2174/1570159x17666191001145550 · Cited by 18

Plants use identical inhibitors to protect their cell wall pectin against microbes and insects

Kirsch, R., Vurmaz, E., Schaefer, C., Eberl, F., Sporer, T., Haeger, W., & Pauchet, Y. (2020) · Ecology and Evolution · doi:10.1002/ece3.6180 · Cited by 18

miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms

Sewastianik, T., Straubhaar, J., Zhao, J., Samur, M., Adler, K., Tanton, H., Shanmugam, V., Nadeem, O., Dennis, P. S., Pillai, V., et al. (2021) · Blood · doi:10.1182/blood.2020009088 · Cited by 18

Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice

Martins, B. B., Hösch, N. G., Alcantara, Q. A., Budas, G. R., Chen, C., Mochly‐Rosen, D., Ferreira, J. C. B., & Zambelli, V. O. (2021) · Biomolecules · doi:10.3390/biom11121798 · Cited by 16

A critical period of prehearing spontaneous Ca2+ spiking is required for hair‐bundle maintenance in inner hair cells

Carlton, A. J., Jeng, J., Grandi, F. C., Faveri, F. D., Ceriani, F., Tomasi, L. D., Underhill, A., Johnson, S. L., Legan, P. K., Kros, C. J., et al. (2023) · The EMBO Journal · doi:10.15252/embj.2022112118 · Cited by 16

Potential safety implications of fatty acid-binding protein inhibition

Warren, W. G., Osborn, M., Duffy, P., Yates, A., & O’Sullivan, S. E. (2024) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2024.117079 · Cited by 17

Prenatal Neuropathologies in Autism Spectrum Disorder and Intellectual Disability: The Gestation of a Comprehensive Zebrafish Model

Kozol, R. A. (2018) · Journal of Developmental Biology · doi:10.3390/jdb6040029 · Cited by 18

Normal spermatogenesis in Fank1 (fibronectin type 3 and ankyrin repeat domains 1) mutant mice

Zhang, J., Zhang, X., Zhang, Y., Zeng, W., Zhao, S., & Liu, M. (2019) · PeerJ · doi:10.7717/peerj.6827 · Cited by 19

Functional roles of human Up-frameshift suppressor 3 (UPF3) proteins: From nonsense-mediated mRNA decay to neurodevelopmental disorders

Deka, B., Chandra, P., & Singh, K. K. (2020) · Biochimie · doi:10.1016/j.biochi.2020.10.011 · Cited by 17

mtor Haploinsufficiency Ameliorates Renal Cysts and Cilia Abnormality in Adult Zebrafish tmem67 Mutants

Zhu, P., Qiu, Q., Harris, P. C., Xu, X., & Lin, X. (2021) · Journal of the American Society of Nephrology · doi:10.1681/asn.2020070991 · Cited by 17

Corticosteroid treatment exacerbates nephrotic syndrome in a zebrafish model of magi2a knockout

Jobst‐Schwan, T., Hoogstraten, C. A., Kolvenbach, C. M., Schmidt, J. M., Kolb, A., Eddy, K., Schneider, R., Ashraf, S., Widmeier, E., Majmundar, A. J., et al. (2019) · Kidney International · doi:10.1016/j.kint.2018.12.026 · Cited by 17

Tek (Tie2) is not required for cardiovascular development in zebrafish

Jiang, Z., Carlantoni, C., Allanki, S., Ebersberger, I., & Stainier, D. Y. R. (2020) · Development · doi:10.1242/dev.193029 · Cited by 17

Pain persists in mice lacking both Substance P and CGRPα signalingPreprint

MacDonald, D. I., Jayabalan, M., Seaman, J. T., Balaji, R., Nickolls, A. R., & Chesler, A. T. (2024) · eLife · doi:10.7554/elife.93754 · Cited by 18

Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome

Chiang, C.-Y., Ching, Y., Chang, T.-Y., Hu, L.-S., Yong, Y. S., Keak, P. Y., Mustika, I., Lin, M., & Liao, B. (2019) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2019.12.009 · Cited by 17

Highly efficient manipulation of nervous system gene expression with NEPTUNE

Mangold, K., Mašek, J., He, J., Lendahl, U., Fuchs, E. V., & Andersson, E. R. (2021) · Cell Reports Methods · doi:10.1016/j.crmeth.2021.100043 · Cited by 16

Transcriptomic changes during stage progression of mycosis fungoides

Xiao, M. Z. X., Hennessey, D., Iyer, A., O’Keefe, S. J., Zhang, F., Sivanand, A., & Gniadecki, R. (2021) · British Journal of Dermatology · doi:10.1111/bjd.20760 · Cited by 16

Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice

Lin, L., Petralia, R. S., Holtzclaw, L. A., Wang, Y., Abebe, D. T., & Hoffman, D. A. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105887 · Cited by 17

Therapeutic Potential of PTB Inhibition Through Converting Glial Cells to Neurons in the Brain

Fu, X.-D., & Mobley, W. C. (2023) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-083022-113120 · Cited by 16

Gene dosage compensation: Origins, criteria to identify compensated genes, and mechanisms including sensor loops as an emerging systems‐level property in cancer

Bravo‐Estupiñan, D. M., Aguilar‐Guerrero, K., Quirós, S., Acón, M., Marín‐Müller, C., Ibáñez-Hernández, M. Á., & Mora-Rodríguez, R. A. (2023) · Cancer Medicine · doi:10.1002/cam4.6719 · Cited by 16

Versatile Genome Engineering Techniques Advance Human Ocular Disease Researches in Zebrafish

Zheng, S., Han, R., Xiang, L., Zhuang, Y., & Jin, Z. (2018) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2018.00075 · Cited by 16

Looking to the future of zebrafish as a model to understand the genetic basis of eye disease

Cavodeassi, F., & Wilson, S. W. (2019) · Human Genetics · doi:10.1007/s00439-019-02055-z · Cited by 16

HSP-Target of Therapeutic Agents in Sepsis Treatment

Vulczak, A., Catalão, C. H. R., de Freitas, L. A. P., & Rocha, M. J. A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20174255 · Cited by 16

Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation

Young, R., Ewan, K., Ferrer, V. P., Allende, M., Godovac-Zimmermann, J., Dale, T., & Wilson, S. (2019) · bioRxiv · doi:10.7554/elife.51447 · Cited by 13

Deletion of bglC triggers a genetic compensation response by awakening the expression of alternative beta-glucosidase

Deflandre, B., Thiébaut, N., Planckaert, S., Jourdan, S., Anderssen, S., Hanikenne, M., Devreese, B. V., Francis, I. M., & Rigali, S. (2020) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2020.194615 · Cited by 14

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Fan, C., Yang, X., Wang, W. W., Wang, J., Li, W., Guo, M., Huang, S., Wang, Z., & Liu, K. (2020) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.314278 · Cited by 16

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Brian, B. F., Guerrero, C. R., & Freedman, T. S. (2020) · Current Protocols in Immunology · doi:10.1002/cpim.104 · Cited by 16

MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer

Acón, M., Geiß, C., Torres-Calvo, J., Bravo‐Estupiñan, D. M., Oviedo, G., Arias-Arias, J. L., Rojas-Matey, L. A., Baéz, E., Vásquez-Vargas, G., Oses-Vargas, Y., et al. (2021) · iScience · doi:10.1016/j.isci.2021.103407 · Cited by 16

Fish mutant, where is thy phenotype?

Balciunas, D. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007197 · Cited by 16

Activation of Rho Family GTPases by Small Molecules

Palsuledesai, C. C., Surviladze, Z., Waller, A., Miscioscia, T. F., Guo, Y., Wu, Y., Strouse, J., Romero, E., Salas, V. M., Curpan, R. F., et al. (2018) · ACS Chemical Biology · doi:10.1021/acschembio.8b00038 · Cited by 18

The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice

Beckers, A., Ott, T., Schuster-Gossler, K., Boldt, K., Alten, L., Ueffing, M., Blum, M., & Gossler, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-33045-2 · Cited by 16

GIPC proteins negatively modulate Plexind1 signaling during vascular development

Carretero-Ortega, J., Chhangawala, Z., Hunt, S., Narvaez, C., Menéndez, J., Gay, C. M., Zygmunt, T., Li, X., & Torres‐Vázquez, J. (2019) · eLife · doi:10.7554/elife.30454 · Cited by 16

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide

Hadji, A., Schmitt, G. K., Schnorenberg, M. R., Roach, L. E., Hickey, C. M., Leak, L. B., Tirrell, M., & LaBelle, J. L. (2019) · Oncotarget · doi:10.18632/oncotarget.27262 · Cited by 16

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Karakaya, M., Macrı̀, S., & Porfiri, M. (2020) · iScience · doi:10.1016/j.isci.2020.101418 · Cited by 15

STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development

Matsuki, T., Iio, A., Ueda, M., Tsuneura, Y., Howell, B. W., & Nakayama, A. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0523-21.2021 · Cited by 14

IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

Landolina, N., Mariotti, F. R., Ingegnere, T., Alicata, C., Ricci, B., Pelosi, A., Veneziani, I., Azzarone, B. G., Garlanda, C., Mantovani, A., et al. (2022) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-003858 · Cited by 15

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Wang, Y., Mack, J. A., Hascall, V., & Maytin, E. V. (2022) · American Journal Of Pathology · doi:10.1016/j.ajpath.2022.08.003 · Cited by 15

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Ampong, I. (2024) · Cogent Business & Management · doi:10.1080/23311975.2024.2315690 · Cited by 15

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Zimmer, A. M., Shir-Mohammadi, K., Kwong, R. W. M., & Perry, S. F. (2019) · Journal of Experimental Biology · doi:10.1242/jeb.215111 · Cited by 15

The recent advances and future perspectives of genetic compensation studies in the zebrafish model

Rouf, M. A., Wen, L., Mahendra, Y., Wang, J., Zhang, K., Liang, S., Wang, Y., Li, Z., Wang, Y., & Wang, G. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2021.12.003 · Cited by 72

Genetic compensation induced by deleterious mutations but not gene knockdowns

Rossi, A., Kontarakis, Z., Gerri, C., Nolte, H., Hölper, S., Krüger, M., & Stainier, D. Y. R. (2015) · Nature · doi:10.1038/nature14580 · Cited by 1,226

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Junker, J. P. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0107-5 · Cited by 4

How widespread is the phenomenon of dosage compensation?

Lucchesi, J. C. (1993) · Seminars in Developmental Biology · doi:10.1006/sedb.1993.1016 · Cited by 5

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Kontarakis, Z., & Stainier, D. Y. R. (2020) · Trends in Genetics · doi:10.1016/j.tig.2020.08.008 · Cited by 41