Genetic compensation: A phenomenon in search of mechanisms

Network biology: understanding the cell's functional organization

Barabási, A.-L., & Oltvai, Z. N. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1272 · Cited by 7,903

Untitled work

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Functional profiling of the Saccharomyces cerevisiae genome

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Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

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The Transcriptional Landscape of the Mammalian Genome

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Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

Raj, A., & van Oudenaarden, A. (2008) · Cell · doi:10.1016/j.cell.2008.09.050 · Cited by 2,593

Antisense Transcription in the Mammalian Transcriptome

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MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

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Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

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RNA‐binding proteins and post‐transcriptional gene regulation

Glisovic, T., Bachorik, J. L., Yong, J., & Dreyfuss, G. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.03.004 · Cited by 1,398

Liver-Specific siRNA-Mediated Stat3 or C3 Knockdown Improves the Outcome of Experimental Autoimmune Myocarditis

Avalle, L., Marino, F., Camporeale, A., Guglielmi, C., Viavattene, D., Bandini, S., Conti, L., Cimino, J. J., Forni, M., Zanini, C., et al. (2020) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2020.05.023 · Cited by 14

Building the vertebrate codex using the gene breaking protein trap library

Ichino, N., Serres, M. R., Urban, R. M., Urban, M. D., Treichel, A. J., Schaefbauer, K. J., Tallant, L., Varshney, G. K., Skuster, K. J., McNulty, M. S., et al. (2020) · eLife · doi:10.7554/elife.54572 · Cited by 15

The Critical Role of AtPAP17 and AtPAP26 Genes in Arabidopsis Phosphate Compensation Network

Farhadi, S., Sabet, M. S., Malboobi, M. A., & Moieni, A. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.565865 · Cited by 15

The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium

Willoughby, P. M., Allen, M., Yu, J. C., Korytnikov, R., Chen, T., Liu, Y., So, I., Wan, H., Macpherson, N. N., Mitchell, J. A., et al. (2021) · eLife · doi:10.7554/elife.66060 · Cited by 15

Slit2 is necessary for optic axon organization in the zebrafish ventral midline

Davison, C., & Zolessi, F. R. (2021) · Cells and Development · doi:10.1016/j.cdev.2021.203677 · Cited by 15

Gene network analysis reveals a role for striatal glutamatergic receptors in dysregulated risk-assessment behavior of autism mouse models

Oron, O., Getselter, D., Shohat, S., Reuveni, E., Lukić, I., Shifman, S., & Elliott, E. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0584-5 · Cited by 15

The analysis of living systems can generate both knowledge and illusions

Jose, A. M. (2020) · eLife · doi:10.7554/elife.56354 · Cited by 13

Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells

Fan, J., & Papadopoulos, V. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010252 · Cited by 16

A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium

Nassir, N., Hyde, G. J., & Baskar, R. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008188 · Cited by 14

Involvement of Neuropeptide Galanin Receptors 2 and 3 in Learning, Memory and Anxiety in Aging Mice

Locker, F., Bieler, L., Nowack, L. M. F., Leitner, J., Brunner, S. M., Zaunmair, P., Kofler, B., & Couillard‐Després, S. (2021) · Molecules · doi:10.3390/molecules26071978 · Cited by 15

SLC38A10 Knockout Mice Display a Decreased Body Weight and an Increased Risk-Taking Behavior in the Open Field Test

Lindberg, F. A., Nordenankar, K., & Fredriksson, R. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.840987 · Cited by 15

Achieving improved accuracy for imputation of ancient DNA

Ausmees, K., & Nettelblad, C. (2022) · Bioinformatics · doi:10.1093/bioinformatics/btac738 · Cited by 16

Hsp70/Hsp90 Organising Protein (Hop): Coordinating Much More than Chaperones

Schwarz, K., Baindur‐Hudson, S., Blatch, G. L., & Edkins, A. L. (2022) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-14740-1_3 · Cited by 13

Prevalence of and gene regulatory constraints on transcriptional adaptation in single cells

Mellis, I. A., Bodkin, N., Melzer, M. E., & Goyal, Y. (2024) · Genome biology · doi:10.1186/s13059-024-03351-2 · Cited by 17

Neurocan regulates axon initial segment organization and neuronal activity

Baidoe‐Ansah, D., Mirzapourdelavar, H., Aleshin, S. E., Schott, B. H., Seidenbecher, C. I., Kaushik, R., & Dityatev, A. E. (2025) · Matrix Biology · doi:10.1016/j.matbio.2025.01.001 · Cited by 14

Genetic identification of Ly75 as a novel quantitative trait gene for resistance to obesity in mice

Makino, K., & Ishikawa, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-36073-0 · Cited by 14

Direct RNA Sequencing for the Study of Synthesis, Processing, and Degradation of Modified Transcripts

Furlan, M., Tanaka, I., Leonardi, T., de Pretis, S., & Pelizzola, M. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00394 · Cited by 14

Spadin Modulates Astrocytic Passive Conductance via Inhibition of TWIK-1/TREK-1 Heterodimeric Channels

Bae, Y., Choi, J. H., Ryoo, K., Kim, A., Kwon, O., Jung, H., Hwang, E. M., & Park, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249639 · Cited by 14

Light control of the peptide-loading complex synchronizes antigen translocation and MHC I trafficking

Brunnberg, J., Herbring, V., Castillo, E. G., Krüger, H., Wieneke, R., & Tampé, R. (2021) · Communications Biology · doi:10.1038/s42003-021-01890-z · Cited by 14

Co-targeting myelin inhibitors and CSPGs markedly enhances regeneration of GDNF-stimulated, but not conditioning-lesioned, sensory axons into the spinal cord

Zhai, J., Kim, H., Han, S. B., Manire, M., Yoo, R., Pang, S., Smith, G. M., & Son, Y. (2021) · eLife · doi:10.7554/elife.63050 · Cited by 14

DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma

Barenboim, M., Kovac, M. B., Ameline, B., Jones, D., Witt, O., Bielack, S., Burdach, S. E. G., Baumhoer, D., & Nathrath, M. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009562 · Cited by 15

Long read sequencing and expression studies ofAHDC1deletions in Xia‐Gibbs syndrome reveal a novel genetic regulatory mechanism

Chander, V., Mahmoud, M., Hu, J., Dardas, Z., Grochowski, C. M., Dawood, M., Khayat, M. M., Li, H., Li, S., Jhangiani, S. N., et al. (2022) · Human Mutation · doi:10.1002/humu.24461 · Cited by 14

Genotyping and Quantification of In Situ Hybridization Staining in Zebrafish

Dobrzycki, T., Krecsmarik, M., & Monteiro, R. M. (2020) · Journal of Visualized Experiments · doi:10.3791/59956-v · Cited by 14

Novel Loss-of-Function Variants in CDC14A are Associated with Recessive Sensorineural Hearing Loss in Iranian and Pakistani Patients

Doll, J., Kolb, S. M., Schnapp, L., Rad, A., Rüschendorf, F., Khan, I., Adli, A., Hasanzadeh, A., Liedtke, D., Knaup, S., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21010311 · Cited by 14

The F-box protein, FBXO7, is required to maintain chromosome stability in humans

Palmer, M. C. L., Neudorf, N. M., Farrell, A. C., Razi, T., Lichtensztejn, Z., & McManus, K. J. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab330 · Cited by 19

The plasminogen receptor directs maintenance of spermatogonial stem cells by targeting BMI1

Zhou, H., Shen, C., Guo, Y., Huang, X., Zheng, B. J., & Wu, Y. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07289-1 · Cited by 14

MAPKs in the early steps of senescence implemEMTation

Anerillas, C., Altés, G., & Gorospe, M. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1083401 · Cited by 13

Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation

El-Brolosy, M. A., Oak, A., Hoang, A. T., Damergi, Y., Fischer, A., Saunders, R. A., Luo, J., Balabaki, A., Guez, J., Whitfield, T. W., et al. (2026) · Science · doi:10.1126/science.aea1272 · Cited by 17

Loss of the exocyst complex component EXOC3 promotes hemostasis and accelerates arterial thrombosis

Walsh, T. G., Li, Y., Williams, C. M., Aitken, E. W., Andrews, R. K., & Poole, A. W. (2021) · Blood Advances · doi:10.1182/bloodadvances.2020002515 · Cited by 13

Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA5-Dependent Signaling

Liang, Z., He, P., Han, Y., & Yun, C. C. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.03.012 · Cited by 12

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish

Saralahti, A. K., Harjula, S.-K. E., Rantapero, T., Uusi-Mäkelä, M. I. E., Kaasinen, M., Junno, M., Piippo, H., Nykter, M., Lohi, O., Rounioja, S., et al. (2023) · PLoS Genetics · doi:10.1371/journal.pgen.1010586 · Cited by 13

Functional analysis of germline VANGL2 variants using rescue assays of vangl2 knockout zebrafish

Derrick, C. J., Szenker‐Ravi, E., Santos‐Ledo, A., Alqahtani, A., Yusof, A., Eley, L., Coleman, A. H. L., Tohari, S., Ng, A. Y. J., Venkatesh, B., et al. (2023) · Human Molecular Genetics · doi:10.1093/hmg/ddad171 · Cited by 13

Intracellular fraction of zona pellucida protein 3 is required for the oocyte-to-embryo transition in mice

Israel, S., Seyfarth, J., Nolte, T., Drexler, H. C. A., Fuellen, G., & Boiani, M. (2023) · Molecular Human Reproduction · doi:10.1093/molehr/gaad038 · Cited by 14

Transcriptional precision in photoreceptor development and diseases – Lessons from 25 years of CRX research

Zheng, Y., & Chen, S. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1347436 · Cited by 14

Animal Models of Autosomal Recessive Parkinsonism

Bastioli, G., Regoni, M., Cazzaniga, F. A., Luca, C. M. G. D., Bistaffa, E., Zanetti, L., Moda, F., Valtorta, F., & Sassone, J. (2021) · Biomedicines · doi:10.3390/biomedicines9070812 · Cited by 13

Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function

Heymans, C., Delcorte, O., Spourquet, C., Villacorte-Tabelin, M., Dupasquier, S., Achouri, Y., Mahibullah, S., Lemoine, P., Balda, M. S., Matter, K., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-93654-2 · Cited by 13

Zebrafish Heme Oxygenase 1a Is Necessary for Normal Development and Macrophage Migration

Luo, K., Ogawa, M., Ayer, A., Britton, W. J., Stocker, R., Kikuchi, K., & Oehlers, S. H. (2022) · Zebrafish · doi:10.1089/zeb.2021.0058 · Cited by 13

From grain to malt: Tracking changes of ultra-low-gluten barley storage proteins after malting

Bahmani, M., Juhász, A., Bose, U., Nye‐Wood, M. G., Blundell, M. J., Howitt, C. A., & Colgrave, M. L. (2023) · Food Chemistry · doi:10.1016/j.foodchem.2023.137189 · Cited by 13

Adaptation of the AID system for stem cell and transgenic mouse research

Pryzhkova, M. V., Xu, M. J., & Jordan, P. W. (2020) · Stem Cell Research · doi:10.1016/j.scr.2020.102078 · Cited by 12

Sensory neuron PIEZO1 deletion inhibits dynamic light touch sensitivity in uninjured mice, prevents neuropathic light touch hypersensitivity, and drives compensatory changes in dorsal root ganglia

Ehlers, V. L., Sriram, A., Stuart, B. A. R., Mecca, C. M., & Stucky, C. L. (2025) · Pain · doi:10.1097/j.pain.0000000000003781 · Cited by 12

Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects

Boel, A., Burger, J. E., Vanhomwegen, M., Beyens, A., Renard, M., Barnhoorn, S., Casteleyn, C. R., Reinhardt, D. P., Descamps, B., Vanhove, C., et al. (2020) · Human Molecular Genetics · doi:10.1093/hmg/ddaa071 · Cited by 12

Visual pigment–deficient cones survive and mediate visual signaling despite the lack of outer segments

Xu, H., Jin, N., Chuang, J.-Z., Zhang, Z., Zhong, X., Zhang, Z., Sung, C.-H., Ribelayga, C., & Fu, Y. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2115138119 · Cited by 12

Clinical, genetic, epidemiologic, evolutionary, and functional delineation of TSPEAR-related autosomal recessive ectodermal dysplasia 14

Jackson, A., Lin, S., Jones, E. A., Chandler, K., Orr, D., Moss, C., Haider, Z., Ryan, G., Holden, S. T., Harrison, M., et al. (2023) · Human Genetics and Genomics Advances · doi:10.1016/j.xhgg.2023.100186 · Cited by 12

Inherited Retinal Degeneration: Towards the Development of a Combination Therapy Targeting Histone Deacetylase, Poly (ADP-Ribose) Polymerase, and Calpain

Dong, Y., Yan, J., Yang, M., Xu, W., Hu, Z., Paquet‐Durand, F., & Jiao, K. (2023) · Biomolecules · doi:10.3390/biom13040581 · Cited by 9

HnRNP Pathologies in Frontotemporal Lobar Degeneration

Jiang, X., Gatt, A. P., & Lashley, T. (2023) · Cells · doi:10.3390/cells12121633 · Cited by 13

Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2

Lee, Y., Yeo, I. S., Kim, N., Lee, D.-K., Kim, K., Yoon, J.-Y., Yi, J., Hong, Y. B., Choi, B., Kosodo, Y., et al. (2023) · eLife · doi:10.7554/elife.84596 · Cited by 12

Loss of T follicular regulatory cell–derived IL-1R2 augments germinal center reactions via increased IL-1

Pyrillou, K., Humphry, M., Kitt, L., Rodgers, A., Nus, M., Bennett, M. R., Smith, K. G. C., Lyons, P., Mallat, Z., & Clarke, M. C. H. (2024) · JCI Insight · doi:10.1172/jci.insight.174005 · Cited by 12

RNAi as a Tool to Study Virulence in the Pathogenic Yeast Candida glabrata

Ishchuk, O. P., Ahmad, K. M., Koruza, K., Bojanovič, K., Sprenger, M., Kasper, L., Brunke, S., Hube, B., Säll, T., Hellmark, T., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01679 · Cited by 12

Terminological and Epistemological Issues in Current Memory Research

Hardt, O. M., & Sossin, W. S. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00336 · Cited by 17

Genetic compensation of γ CaMKII, an evolutionarily conserved gene

Rothschild, S. C., Ingram, S., Lu, F., Thisse, B., Thisse, C., Parkerson, J. A., & Tombes, R. M. (2020) · Gene · doi:10.1016/j.gene.2020.144567 · Cited by 12

Glutamatergic fast-spiking parvalbumin neurons in the lateral hypothalamus: Electrophysiological properties to behavior

Siemian, J. N., Sarsfield, S., & Aponte, Y. (2020) · Physiology & Behavior · doi:10.1016/j.physbeh.2020.112912 · Cited by 12

Modeling autism spectrum disorders in zebrafish

Dreosti, E., Hoffman, E. J., & Rihel, J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817528-6.00026-7 · Cited by 13

Eukaryotic translation initiation factor 5A and its posttranslational modifications play an important role in proliferation and potentially in differentiation of the human enteric protozoan parasite Entamoeba histolytica

Jeelani, G., & Nozaki, T. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1008909 · Cited by 12

Learning and Stroke Recovery: Parallelism of Biological Substrates

Joy, M. T., & Carmichael, S. T. (2021) · Seminars in Neurology · doi:10.1055/s-0041-1725136 · Cited by 12

P2Y 2 deficiency impacts adult neurogenesis and related forebrain functions

Ali, A. A. H., Abdel‐Hafiz, L., Tundo‐Lavalle, F., Hassan, S. A., & von Gall, C. (2021) · The FASEB Journal · doi:10.1096/fj.202002419rr · Cited by 13

Deconstructing the molecular genetics behind the PINK1/Parkin axis in Parkinson’s disease using Drosophila melanogaster as a model organism

Ganesan, S., & Parvathi, V. D. (2021) · Egyptian Journal of Medical Human Genetics · doi:10.1186/s43042-021-00208-2 · Cited by 12

Testis-enriched Asb12 is not required for spermatogenesis and fertility in mice

Zhang, R., Xu, J., Shen, C., Zhang, X., Li, S., Lv, J., Xu, D., Huang, X., Zheng, B. J., Liu, M., et al. (2022) · Translational Andrology and Urology · doi:10.21037/tau-21-900 · Cited by 12

A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair

Velasco-Avilés, S., Patel, N., Casillas-Bajo, Á., Frutos‐Rincón, L., Velasco, E., Gallar, J., Arthur‐Farraj, P., Gomez-Sanchez, J. A., & Cabedo, H. (2021) · Apollo (University of Cambridge) · doi:10.17863/cam.80377 · Cited by 12

Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney

Wesselman, H. M., Gatz, A. E., Pfaff, M. R., Arceri, L., & Wingert, R. A. (2023) · Cells · doi:10.3390/cells12040666 · Cited by 12

Biophysical model of muscle spindle encoding

Housley, S. N., Powers, R. K., Nardelli, P., Lee, S., Blum, K. P., Bewick, G. S., Banks, R. W., & Cope, T. C. (2023) · Experimental Physiology · doi:10.1113/ep091099 · Cited by 12

Advanced 3D In Vitro Lung Fibrosis Models: Contemporary Status, Clinical Uptake, and Prospective Outlooks

Jain, N., Bhushan, B. L. S., Natarajan, M., Mehta, R., Saini, D. K., & Chatterjee, K. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.3c01499 · Cited by 13

Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression

Moreno, R. L., Williams, K., Jones, K. L., & Ribera, A. B. (2018) · PLoS ONE · doi:10.1371/journal.pone.0199233 · Cited by 12

Mammalian sperm contain two factors for calcium release and egg activation: Phospholipase C zeta and a cryptic activating factor

Jones, K. T. (2018) · Molecular Human Reproduction · doi:10.1093/molehr/gay038 · Cited by 12

Zebrafish embryogenesis – A framework to study regulatory RNA elements in development and disease

Zaucker, A., Kumari, P., & Sampath, K. (2019) · Developmental Biology · doi:10.1016/j.ydbio.2019.01.008 · Cited by 13

ATR-16 syndrome: mechanisms linking monosomy to phenotype

Babbs, C., Brown, J. M., Horsley, S. W., Slater, J., Maifoshie, E., Kumar, S., Ooijevaar, P., Kriek, M., Dixon‐McIver, A., Harteveld, C. L., et al. (2020) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2019-106528 · Cited by 12

Pcdh18a regulates endocytosis of E-cadherin during axial mesoderm development in zebrafish

Bösze, B., Mattes, B., Sinner, C., Stricker, K., Gourain, V., Thumberger, T., Tlili, S., Weber, S., Wittbrodt, J., Saunders, T. E., et al. (2020) · Histochemistry and Cell Biology · doi:10.1007/s00418-020-01887-5 · Cited by 12

The Consequences of Abnormal Gene Dosage: Lessons from Chromosome 18

Cody, J. D. (2020) · Trends in Genetics · doi:10.1016/j.tig.2020.06.006 · Cited by 10

CRISPR/Cas9 small promoter deletion in H19 lncRNA is associated with altered cell morphology and proliferation

Santos, R. D. S., Pinheiro, D. P., Teixeira, L. P. R., Sales, S. L. A., Luciano, M. C. D. S., Melo, M. M. D. L., Pinheiro, R. F., Tavares, K. C. S., Furtado, G. P., Pessoa, C., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-97058-0 · Cited by 12

APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites

Constantin, D., Dubuis, G., Rubio, M. D. C. C., & Widmann, C. (2021) · FEBS Journal · doi:10.1111/febs.16202 · Cited by 12

Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells

Cabel, C. R., Alizadeh, E., Robbins, D. J., Ahmed, Y. F., Lee, E. N., & Thorne, C. A. (2019) · Developmental Cell · doi:10.1016/j.devcel.2019.05.039 · Cited by 12

Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells

Dominguez, M., Trümper, V., Mota, A. C., Brüne, B., & Namgaladze, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.906127 · Cited by 15

Separation of transcriptional repressor and activator functions in Drosophila HDAC3

Tang, M., Regadas, I., Belikov, S. V., Shilkova, O., Xu, L., Wernersson, E., Liu, X., Wu, H., Bienko, M., & Mannervik, M. (2023) · Development · doi:10.1242/dev.201548 · Cited by 11

Potential roles of lncRNA MALAT1-miRNA interactions in ocular diseases

Nasrolahi, A., Pour, F. K., Salehi, A. M., Kempisty, B., Hajizadeh, M., Feghhi, M., Azizidoost, S., & Farzaneh, M. (2023) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-023-00787-2 · Cited by 11

Microplastics enhanced the allelopathy of pyrogallol on toxic Microcystis with additional risks: Microcystins release and greenhouse gases emissions

Du, L., Liu, Q., Wang, L., Lyu, H., & Tang, J. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.173864 · Cited by 11

Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC

Karpińska, K., Mehlich, D., Sabbasani, V. R., Łomiak, M., Torres‐Ayuso, P., Wróbel, K., Truong, V. N.-P., Serwa, R. A., Swenson, R. E., Brognard, J., et al. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c00577 · Cited by 12

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly

Weger, M., Weger, B. D., Schink, A., Takamiya, M., Stegmaier, J., Gobet, C., Parisi, A., Kobitski, A. Y., Mertes, J., Krone, N. P., et al. (2020) · eLife · doi:10.7554/elife.57068 · Cited by 11

The COP9 signalosome subunit 3 is necessary for early embryo survival by way of a stable protein deposit in mouse oocytes

Israel, S., Drexler, H. C. A., Fuellen, G., & Boiani, M. (2021) · Molecular Human Reproduction · doi:10.1093/molehr/gaab048 · Cited by 11

A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair

Velasco-Aviles, S., Patel, N., Casillas-Bajo, A., Frutos-Rincón, L., Velasco-Serna, E., Gallar, J., Arthur‐Farraj, P., Gomez-Sanchez, J. A., & Cabedo, H. (2022) · eLife · doi:10.7554/elife.72917 · Cited by 13

Plasmodium berghei-Mediated NRF2 Activation in Infected Hepatocytes Enhances Parasite Survival

Bindschedler, A., Schmuckli‐Maurer, J., Wacker, R., Kramer, N., Rehmann, R., Caldelari, R., & Heussler, V. T. (2022) · Cellular Microbiology · doi:10.1155/2022/7647976 · Cited by 11

Mog1 deficiency promotes cardiac contractile dysfunction and isoproterenol-induced arrhythmias associated with cardiac fibrosis and Cx43 remodeling

Zhao, M., Han, M., Liang, L., Song, Q., Li, X., Du, Y., Hu, D., Cheng, Y., Wang, Q. K., & Ke, T. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2022.166429 · Cited by 11

Mutation of foxl1 Results in Reduced Cartilage Markers in a Zebrafish Model of Otosclerosis

Hawkey-Noble, A., Pater, J. A., Kollipara, R., Fitzgerald, M., Maekawa, A. S., Kovács, C. S., Young, T., & French, C. R. (2022) · Genes · doi:10.3390/genes13071107 · Cited by 11

Compensatory Upregulation of LPA2 and Activation of the PI3K-Akt Pathway Prevent LPA5-Dependent Loss of Intestinal Epithelial Cells in Intestinal Organoids

Liang, Z., & Yun, C. C. (2022) · Cells · doi:10.3390/cells11142243 · Cited by 11

Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation

Olabiyi, B. F., Schmöle, A., Beins, E. C., & Zimmer, A. (2023) · Scientific Reports · doi:10.1038/s41598-023-37702-z · Cited by 11

Optogenetic modulation of guanine nucleotide exchange factors of Ras superfamily proteins directly controls cell shape and movement

Pal, D. S., Lin, Y., Zhan, H., Banerjee, T., Kuhn, J., Providence, S., & Devreotes, P. N. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1195806 · Cited by 10

Opposing effects of acute versus chronic inhibition of p53 on decitabine’s efficacy in myeloid neoplasms

Tamura, M., Yonezawa, T., Liu, X., Asada, S., Hayashi, Y., Fukuyama, T., Tanaka, Y., Kitamura, T., & Goyama, S. (2019) · Scientific Reports · doi:10.1038/s41598-019-44496-6 · Cited by 11

gdnf affects early diencephalic dopaminergic neuron development through regulation of differentiation‐associated transcription factors in zebrafish

Wong, C. E. D., Hua, K., Monis, S., Saxena, V., Norazit, A., Noor, S. M., & Ekker, M. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15108 · Cited by 12

The Purinergic Nature of Pseudoxanthoma Elasticum

Kauffenstein, G., Martin, L., & Saux, O. L. (2024) · Biology · doi:10.3390/biology13020074 · Cited by 10

Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases

Hector, M., Langmann, T., & Wolf, A. (2024) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2024.101249 · Cited by 10

Implication of system xc− in neuroinflammation during the onset and maintenance of neuropathic pain

Beckers, P., do Nascimento, I. B., Charlier, M., Desmet, N., Massie, A., & Hermans, E. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03112-9 · Cited by 13

Considerations for the Use of Mutation as a Regulatory Endpoint in Risk Assessment

Klapacz, J., & Gollapudi, B. B. (2019) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22318 · Cited by 10

When all is not lost: considering genetic compensation in laboratory animals

Bunton-Stasyshyn, R. K. A., Wells, S. E., & Teboul, L. (2019) · Lab Animal · doi:10.1038/s41684-019-0397-4 · Cited by 10

Rapid adaptation of signaling networks in the fungal pathogen Magnaporthe oryzae

Bohnert, S., Antelo, L., Grünewald, C., Yemelin, A., Andresen, K., & Jacob, S. (2019) · BMC Genomics · doi:10.1186/s12864-019-6113-3 · Cited by 12

Whole embryo culture, transcriptomics and RNA interference identify TBX1 and FGF11 as novel regulators of limb development in the mouse

Téjédor, G., Laplace-Builhe, B., Luz‐Crawford, P., Assou, S., Barthelaix, A., Mathieu, M. N., Kissa, K., Jørgensen, C., Collignon, J., Chuchana, P., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-60217-w · Cited by 11

HO-CO pathway activation may be associated with hippocampal μ and δ opioid receptors in inhibiting inflammatory pain aversiveness and nociception in WT but not NOS2-KO mice

Cazuza, R. A., Arantes, A. L. F., Pol, O., & Leite‐Panissi, C. R. A. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.01.002 · Cited by 10

The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus

Beckers, A., Fuhl, F., Ott, T., Boldt, K., Brislinger-Engelhardt, M. M., Walentek, P., Schuster-Gossler, K., Hegermann, J., Alten, L., Kremmer, E., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-92495-3 · Cited by 10

A tapt1 knock-out zebrafish line with aberrant lens development and impaired vision models human early-onset cataract

Jarayseh, T., Guillemyn, B., Saffel, H. D., Bek, J. W., Syx, D., Symoens, S., Gansemans, Y., Nieuwerburgh, F. V., Jagadeesh, S. M., Raja, J., et al. (2023) · Human Genetics · doi:10.1007/s00439-022-02518-w · Cited by 10

Disruption of the foxe1 gene in zebrafish reveals conserved functions in development of the craniofacial skeleton and the thyroid

Raterman, S. T., den Hoff, J. W. V., Dijkstra, S., Vriend, C. D., Morsche, T. T., Broekman, S., Zethof, J., de Vrieze, E., Wagener, F. A. D. T. G., & Metz, J. R. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1143844 · Cited by 10

DivergentHemogengenes of teleosts and mammals share conserved roles in erythropoiesis: Analysis using transgenic and mutant zebrafish

Peters, M. J., Parker, S. K., Grim, J. M., Allard, C. A., Levin, J., & Detrich, H. W. (2018) · Biology Open · doi:10.1242/bio.035576 · Cited by 10

Site-directed RNA editing (SDRE): Off-target effects and their countermeasures

Mao, S., Liu, Y., Huang, S., Huang, X., & Chi, T. H. (2019) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2019.11.005 · Cited by 10

Cannabinoids modulate associative cerebellar learning via alterations in behavioral state

Albergaria, C., Silva, N. T., Darmohray, D. M., & Carey, M. R. (2020) · eLife · doi:10.7554/elife.61821 · Cited by 12

The recent advances and future perspectives of genetic compensation studies in the zebrafish model

Rouf, M. A., Wen, L., Mahendra, Y., Wang, J., Zhang, K., Liang, S., Wang, Y., Li, Z., Wang, Y., & Wang, G. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2021.12.003 · Cited by 72

Genetic compensation induced by deleterious mutations but not gene knockdowns

Rossi, A., Kontarakis, Z., Gerri, C., Nolte, H., Hölper, S., Krüger, M., & Stainier, D. Y. R. (2015) · Nature · doi:10.1038/nature14580 · Cited by 1,226

Detouring the roadblocks in gene expression

Junker, J. P. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0107-5 · Cited by 4

How widespread is the phenomenon of dosage compensation?

Lucchesi, J. C. (1993) · Seminars in Developmental Biology · doi:10.1006/sedb.1993.1016 · Cited by 5

Genetics in Light of Transcriptional Adaptation

Kontarakis, Z., & Stainier, D. Y. R. (2020) · Trends in Genetics · doi:10.1016/j.tig.2020.08.008 · Cited by 41