Cited by 416Advanced Causal Inference TechniquesPhilosophy of Biology and Scientific ExplanationMethodologies in Health Research and Practice

The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.

Observational Research, Randomised Trials, and Two Views of Medical Science

Open access
Vandenbroucke, Jan P·2008·PLoS Medicine

Abstract

Two views exist of medical science, says the author, one emphasizing discovery and explanation, the other emphasizing evaluation of interventions.

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Crossref · 10.1371/journal.pmed.0050067

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Figure 1 Axis of Haphazardness of Exposure
Figure 1 Axis of Haphazardness of ExposureCC BY · PubMed Central
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Figure 2 Axis of MultiplicityCC BY · PubMed Central

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Citations

Cites

Show all 66 references

Research works printed but not linked: 27

  1. Laine, 2007, N Engl J Med, 356, 2734
  2. Vandenbroucke, 1994, Lancet, 344, 1453
  3. Vandenbroucke, 2001, N Engl J Med, 344, 1527
  4. Vandenbroucke, 2005, N Engl J Med, 353, 1297
  5. Glasziou, 2007, BMJ, 334, 349
  6. Vandenbroucke, 2001, Ann Intern Med, 134, 330
  7. Vandenbroucke, 2004, Lancet, 363, 1728
  8. Schulz, 2002, Lancet, 359, 614
  9. Miettinen, 1983, Stat Med, 2, 267
  10. Vandenbroucke, 2006, CMAJ, 174, 645
  11. Papanikolaou, 2006, CMAJ, 174, 635
  12. Jick, 1978, Am J Epidemiol, 107, 1
  13. Djulbegovic, 2000, Lancet, 356, 635
  14. Kumar, 2005, BMJ, 331, 1295
  15. Rothman, 1990, Epidemiology, 1, 43
  16. Greenland, 2007, Int J Epidemiol, 36, 944
  17. Lipton, 2005, Science, 307, 219
  18. Brush, 2005, Science, 308, 1409
  19. Rothwell, 2005, Lancet, 365, 176
  20. Joost, 2002, Am J Respir Crit Care Med, 165, 795
  21. Goodman, 1998, Am J Epidemiol, 147, 807
  22. Moonesinghe, 2007, PLoS Med, 4, e28
  23. Khoury, 2007, Int J Epidemiol, 36, 439
  24. Maclure, 1993, Epidemiol Rev, 15, 328
  25. Mayes, 1988, Int J Epidemiol, 17, 680
  26. Schulz, 2002, Lancet, 359, 431
  27. Gould, 2000, Science, 287, 253

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Metadata

Authors
Vandenbroucke, J. P.
Affiliations
Royal Netherlands Academy of Arts and Sciences (NL)
Corresponding author
Vandenbroucke, Jan P
Venue
PLoS Medicine
Published
2008-03-11
Volume
5
Issue
3
Pages
e67
ISSN
  • 1549-1277 (ISSN-L)
  • 1549-1676
OpenAlex
W2090226269
Cited by
416
References
66
Citations by year
2026: 15 · 2025: 5 · 2024: 15 · 2023: 32 · 2022: 22 · 2021: 23 · 2020: 23 · 2019: 25 · 2018: 14 · 2017: 14 · 2016: 17 · 2015: 26 · 2014: 20 · 2013: 36 · 2012: 31
FWCI
30.62
Type
journal article
Language
en
Open access
Locations
  • PLoS Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Figshare (submittedVersion, cc-by)
Funders
London School of Hygiene and Tropical Medicine
Topics
  • Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
  • Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy of Biology and Scientific Explanation
  • Health Sciences › Nursing › Research and Theory › Methodologies in Health Research and Practice
Keywords
observational studies, randomised trials, medical sciences, intervention evaluation, philosophy of medicine
MeSH terms
Contraceptives, Oral, Evaluation Studies as Topic, Factor V, Female, Follow-Up Studies, Humans, Prospective Studies, Retrospective Studies, Case-Control Studies, Randomized Controlled Trials as Topic, Biomedical Research, Venous Thromboembolism

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