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Observational Research, Randomised Trials, and Two Views of Medical Science
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Two views exist of medical science, says the author, one emphasizing discovery and explanation, the other emphasizing evaluation of interventions.
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“Because the strengths and limitations of methods used to conduct research with routinely collected data may be contentious, a clear description of a study’s objectives is essential [23,24].”
From The Reporting of Studies Conducted Using Observational Routinely-Collected Health Data (RECORD) statement. (2015) · cites this paper as [23]
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Metadata
- Authors
- Vandenbroucke, J. P.
- Affiliations
- Royal Netherlands Academy of Arts and Sciences (NL)
- Corresponding author
- Vandenbroucke, Jan P
- ORCID
- Vandenbroucke, Jan P
- Venue
- PLoS Medicine
- Publisher
- Public Library of Science (PLoS)
- Published
- 2008-03-11
- Volume
- 5
- Issue
- 3
- Pages
- e67
- ISSN
- 1549-1277 (ISSN-L)
- 1549-1676
- PMC
- PMC2265762
- OpenAlex
- W2090226269
- Cited by
- 416
- References
- 66
- Citations by year
- 2026: 15 · 2025: 5 · 2024: 15 · 2023: 32 · 2022: 22 · 2021: 23 · 2020: 23 · 2019: 25 · 2018: 14 · 2017: 14 · 2016: 17 · 2015: 26 · 2014: 20 · 2013: 36 · 2012: 31
- FWCI
- 30.62
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Funders
- London School of Hygiene and Tropical Medicine
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy of Biology and Scientific Explanation
- Health Sciences › Nursing › Research and Theory › Methodologies in Health Research and Practice
- Keywords
- observational studies, randomised trials, medical sciences, intervention evaluation, philosophy of medicine
- MeSH terms
- Contraceptives, Oral, Evaluation Studies as Topic, Factor V, Female, Follow-Up Studies, Humans, Prospective Studies, Retrospective Studies, Case-Control Studies, Randomized Controlled Trials as Topic, Biomedical Research, Venous Thromboembolism
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