The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Point-of-Care Testing for Infectious Diseases: Diversity, Complexity, and Barriers in Low- And Middle-Income Countries
Open accessAbstract
Enthusiasm and hope are increasing around point-of-care (POC) diagnostics for diseases of global health importance. The mere availability of rapid or simple tests does not automatically ensure their adoption or scale-up. A range of barriers prevent the successful use of POC testing—economic, regulatory, and policy-related, as well as user/provider perceptions and cultural barriers. Technology as such does not define a POC test. Rather, it is the successful use at the POC that defines a diagnostic process as POC testing. Thus, the focus must be on POC testing programs, rather than POC technologies. We discuss a framework that envisions POC testing as a spectrum of technologies (simplest to more sophisticated), users (lay persons to highly trained), and settings (homes, communities, clinics, peripheral laboratories, and hospitals). A deeper appreciation of this diversity in target product profiles, and likely barriers in each setting, might help test developers and public health managers to identify the most impactful product and delivery model.
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Cites
Point-of-Care Diagnostics for Global Health
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Point-of-care nucleic acid testing for infectious diseases
Niemz, A., Ferguson, T. M., & Boyle, D. S. (2011) · Trends in Biotechnology · doi:10.1016/j.tibtech.2011.01.007 · Cited by 838
Point-of-care tests for diagnosing infections in the developing world
Peeling, R. W., & Mabey, D. (2010) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2010.03279.x · Cited by 500
Accuracy of Rapid Influenza Diagnostic Tests: A Meta-analysis
Chartrand, C., Leeflang, M. M. G., Minion, J., Brewer, T., & Pai, M. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-156-7-201204030-00403 · Cited by 483
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Barriers to HIV testing in Europe: a systematic review
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Cited by
Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection
Dinnes, J., Deeks, J. J., Berhane, S., Taylor, M., Adriano, A., Davenport, C., Dittrich, S., Emperador, D., Takwoingi, Y., Cunningham, J., et al. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013705.pub2 · Cited by 591
Point-of-Care Diagnostics: Recent Developments in a Connected Age
Nayak, S., Blumenfeld, N. R., Laksanasopin, T., & Sia, S. K. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04630 · Cited by 508
Kelley, S. O., Mirkin, C. A., Walt, D. R., Ismagilov, R. F., Toner, M., & Sargent, E. H. (2014) · Nature Nanotechnology · doi:10.1038/nnano.2014.261 · Cited by 398
Tuberculosis Diagnostics in 2015: Landscape, Priorities, Needs, and Prospects
Pai, M., & Schito, M. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu803 · Cited by 193
Self-citationDetection of Mycobacterium tuberculosis by EasyNAT Diagnostic Kit in Sputum Samples from Tanzania
Mhimbira, F. A., Bholla, M., Sasamalo, M., Mukurasi, W., Hella, J. J., Jugheli, L., & Reither, K. (2015) · Journal of Clinical Microbiology · doi:10.1128/jcm.03037-14 · Cited by 17
Metadata
- Authors
- Pai, N. P., Vadnais, C., Denkinger, C., Engel, N., & Pai, M.
- Venue
- PLoS Medicine
- Publisher
- Public Library of Science (PLoS)
- Published
- 2012-09-04
- Volume
- 9
- Issue
- 9
- Pages
- e1001306
- ISSN
- 1549-1277 (ISSN-L)
- 1549-1676
- OpenAlex
- W2066218616
- Cited by
- 593
- References
- 31
- FWCI
- 20.93
- Type
- journal article
- Language
- en
- Open access
- gold
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- Pai, N. P., Vadnais, C., Denkinger, C., Engel, N., & Pai, M. (2012). Point-of-Care Testing for Infectious Diseases: Diversity, Complexity, and Barriers in Low- And Middle-Income Countries. PLoS Medicine. https://doi.org/10.1371/journal.pmed.1001306
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