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Adipocyte hypertrophy, fatty liver, and metabolic risk factors in South Asians: The Molecular Study of Health and Risk in Ethnic Groups (mol-SHARE)
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OBJECTIVE: We sought to determine if differences in the distribution and characteristics of adipose tissue between South Asians and white Caucasians account for differences in risk factors for cardiovascular disease. RESEARCH DESIGN AND METHODS: We recruited 108 healthy South Asians (36.8 years) and white Caucasians (34.2 years) within three BMI strata. Body composition, adipocyte size, abdominal fat area, and hepatic adiposity were assessed and related to fasting glucose, insulin, lipids and adiponectin. RESULTS: After adjustment for age, sex, and BMI, South Asians compared to white Caucasians had higher ln fasting insulin (mean difference (MD): 0.44; 95% CI: 0.20-0.69), lower HDL cholesterol (md: -0.13; 95% CI:-0.26 to -0.01), and lower adiponectin (md: -2.38; 95% CI: -3.59 to -1.17). South Asians also had more body fat (md: 2.69; 95% CI: 0.70 to 4.69), lower lean muscle mass (md: -3.25; 95%CI: -5.35 to -1.14), increased waist to hip ratio (md: 0.03; 95% CI: 0.01-0.05), less superficial subcutaneous abdominal adipose tissue (md: -2.94; 95% CI: -5.56 to-0.32), more deep/visceral to superficial adipose tissue ratio (md 0.34; 95% CI: 0.02 to 0.65), and more liver fat (md: 7.43%; 95% CI: 2.30 to 12.55%). Adipocyte area was increased in South Asians compared to white Caucasians (md: 64.26; 95% CI: 24.3 to 104.1) units(2). Adjustment for adipocyte area attenuated the ethnic differences in insulin (md: 0.22; 95% CI: -0.07 to 0.51), HDL (md: -0.01; 95% CI: -0.16 to 0.13) and adiponectin (md: -1.11; 95% CI: -2.61 to 0.39). Adjustment for differences in adipocyte area and fat distribution attenuated the ethnic difference in liver fat (md: 5.19; 95% CI: 0.31 to 10.06). CONCLUSION: South Asians have an increased adipocyte area compared to white Caucasians. This difference accounts for the ethnic differences in insulin, HDL cholesterol, adiponectin, and ectopic fat deposition in the liver.
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“For example, South Asians have higher body fat content, waist to hip ratio, visceral fat to subcutaneous fat ratio, and adipocyte area than Caucasians matched for age, sex, and body mass index (BMI) (15,16).”
From The CardioMetabolic Health Alliance (2015) · cites this paper as [15]
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Cites
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423
Enzymatic determination of total serum cholesterol.
Allain, C. C., Poon, L. S., Chan, C. S. G., Richmond, W., & Fu, P. C. (1974) · Clinical Chemistry · doi:10.1093/clinchem/20.4.470 · Cited by 9,845
Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
Fontana, L., Eagon, J. C., Trujillo, M. E., Scherer, P. E., & Klein, S. (2007) · Diabetes · doi:10.2337/db06-1656 · Cited by 1,417
Anand, S. S., Yusuf, S., Vuksan, V., Devanesen, S., Teo, K. K., Montague, P. A., Kelemen, L. E., Yi, C., Lonn, E., Gerstein, H. C., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02502-2 · Cited by 1,060
Self-citationJoshi, P., Islam, S., Pais, P. S., Reddy, S., Prabhakaran, D., Kazmi, K. A., Pandey, M. R., Haque, S., Mendis, S., Rangarajan, S., et al. (2007) · JAMA · doi:10.1001/jama.297.3.286 · Cited by 1,038
Self-citationAcquired and Inherited Lipodystrophies
Garg, A. (2004) · New England Journal of Medicine · doi:10.1056/nejmra025261 · Cited by 940
Weyer, C., Foley, J. E., Bogardus, C., Tataranni, P. A., & Pratley, R. E. (2000) · Diabetologia · doi:10.1007/s001250051560 · Cited by 799
The assessment of insulin resistance in man
Wallace, T. M., & Matthews, D. R. (2002) · Diabetic Medicine · doi:10.1046/j.1464-5491.2002.00745.x · Cited by 685
Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology
Arner, E., Westermark, P. O., Spalding, K. L., Britton, T., Rydén, M., Frisén, J., Bernard, S., & Arner, P. (2010) · Diabetes · doi:10.2337/db09-0942 · Cited by 645
Defining Obesity Cut Points in a Multiethnic Population
Razak, F. A., Anand, S. S., Shannon, H. S., Vuksan, V. V. V., Davis, B. C., Jacobs, R., Teo, K. K., McQueen, M., & Yusuf, S. (2007) · Circulation · doi:10.1161/circulationaha.106.635011 · Cited by 558
Self-citation
Research works printed but not linked: 2
- 2003, Diabetes Atlas Second Edition Executive Summary. Brussels: International Diabetes Federation.
- MA Tarnopolsky, 2007, Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity., Am J Physiol Regul Integr Comp Physiol, 292, R1271, 10.1152/ajpregu.00472.2006 · DOI · Paper page
Cited by
Sorted by citations
Lee, M., Wu, Y., & Fried, S. K. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.10.001 · Cited by 861
Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity
Hammarstedt, A., Gogg, S., Hedjazifar, S., Nerstedt, A., & Smith, U. (2018) · Physiological Reviews · doi:10.1152/physrev.00034.2017 · Cited by 462
The CardioMetabolic Health Alliance
Sperling, L. S., Mechanick, J. I., Neeland, I. J., Herrick, C. J., Després, J.-P., Ndumele, C. E., Vijayaraghavan, K., Handelsman, Y., Puckrein, G. A., Araneta, M. R. G., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.06.1328 · Cited by 294
Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management
Sattar, N. A., & Gill, J. M. R. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(15)00326-5 · Cited by 268
Tillin, T., Hughes, A. D., Wang, Q., Würtz, P., Ala‐Korpela, M., Sattar, N. A., Forouhi, N. G., Godsland, I. F., Eastwood, S. V., McKeigue, P., et al. (2015) · Diabetologia · doi:10.1007/s00125-015-3517-8 · Cited by 227
Type 2 diabetes as a disease of ectopic fat?
Sattar, N. A., & Gill, J. M. R. (2014) · BMC Medicine · doi:10.1186/s12916-014-0123-4 · Cited by 223
Visceral and Subcutaneous Fat Quality and Cardiometabolic Risk
Rosenquist, K. J., Pedley, A., Massaro, J. M., Therkelsen, K. E., Murabito, J. M., Hoffmann, U., & Fox, C. S. (2013) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2012.11.021 · Cited by 223
Adipocyte size as a determinant of metabolic disease and adipose tissue dysfunction
Laforest, S., Labrecque, J., Michaud, A., Cianflone, K., & Tchernof, A. (2015) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2015.1041582 · Cited by 222
Type II Diabetes Mellitus in Arabic-Speaking Countries
Badran, M., & Laher, I. (2012) · International Journal of Endocrinology · doi:10.1155/2012/902873 · Cited by 170
Shah, A., Kandula, N., Lin, F., Allison, M., Carr, J., Herrington, D., Liu, K., & Kanaya, A. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.219 · Cited by 146
Ethnicity and Type 2 diabetes in the UK
Goff, L. M. (2019) · Diabetic Medicine · doi:10.1111/dme.13895 · Cited by 175
WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4
Hammarstedt, A., Hedjazifar, S., Jenndahl, L. E., Gogg, S., Grünberg, J. R., Gustafson, B., Klimčáková, E., Štich, V., Langin, D., Laakso, M., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1211255110 · Cited by 157
Adipose Tissue Fibrosis: Mechanisms, Models, and Importance
DeBari, M. K., & Abbott, R. D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176030 · Cited by 153
Restricted Adipogenesis in Hypertrophic Obesity
Gustafson, B., Hammarstedt, A., Hedjazifar, S., & Smith, U. (2013) · Diabetes · doi:10.2337/db13-0473 · Cited by 142
Cardiovascular risk among South Asians living in Canada: a systematic review and meta-analysis
Rana, A., de Souza, R. J., Kandasamy, S., Lear, S. A., & Anand, S. S. (2014) · CMAJ Open · doi:10.9778/cmajo.20130064 · Cited by 137
Self-citationMicroenvironmental Control of Adipocyte Fate and Function
Pope, B. D., Warren, C. R., Parker, K. K., & Cowan, C. A. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.05.005 · Cited by 124
Body fat, metabolic syndrome and hyperglycemia in South Asians
Misra, A., Soares, M. J., Mohan, V., Shajith Anoop, S., Vishnu, A., Vaidya, R., & Pradeepa, R. (2018) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2018.08.001 · Cited by 120
Ethnic differences in serum adipokine and C-reactive protein levels: the multiethnic cohort
Morimoto, Y., Conroy, S. M., Ollberding, N. J., Kim, Y.-J., Lim, U., Cooney, R. V., Franke, A. A., Wilkens, L. R., Hernandez, B. Y., Goodman, M. T., et al. (2014) · International Journal of Obesity · doi:10.1038/ijo.2014.25 · Cited by 116
Gustafson, B., & Smith, U. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.04.812 · Cited by 114
Trouwborst, I., Bowser, S. M., Goossens, G. H., & Blaak, E. E. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00077 · Cited by 121
Gašević, D., Frohlich, J. J., Mancini, G. B. J., & Lear, S. A. (2011) · Metabolism · doi:10.1016/j.metabol.2011.09.009 · Cited by 106
Ye, R. Z., Richard, G. M., Gévry, N. Y., Tchernof, A., & Carpentier, A. C. (2021) · Endocrine Reviews · doi:10.1210/endrev/bnab018 · Cited by 110
Body Composition in Asians and Caucasians
Haldar, S., Chia, S. C., & Henry, C. J. (2015) · Advances in Food and Nutrition Research · doi:10.1016/bs.afnr.2015.07.001 · Cited by 100
Gulati, S., & Misra, A. (2017) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2017.92 · Cited by 96
Obesity phenotypes: depot-differences in adipose tissue and their clinical implications
Guglielmi, V., & Sbraccia, P. (2017) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-017-0467-9 · Cited by 103
Iliodromiti, S., McLaren, J., Ghouri, N., Miller, M. R., Leinhard, O. D., Linge, J., Ballantyne, S. A., Platt, J., Foster, J., Hanvey, S., et al. (2022) · Diabetologia · doi:10.1007/s00125-022-05803-5 · Cited by 95
Ethnic differences in adiposity and diabetes risk – insights from genetic studies
Yaghootkar, H., Whitcher, B. J., Bell, J. D., & Thomas, E. L. (2020) · Journal of Internal Medicine · doi:10.1111/joim.13082 · Cited by 94
van Eyk, H. J., Paiman, E. H. M., Bizino, M. B., de Heer, P., Geelhoed-Duijvestijn, P. H., Kharagjitsingh, A. V., Smit, J. W. A., Lamb, H. J., Rensen, P. C. N., & Jazet, I. M. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0890-5 · Cited by 90
Echiburú, B., Pérez‐Bravo, F., Galgani, J. E., Sandoval, D., Saldías, C., Crisosto, N., Maliqueo, M. A., & Sir‐Petermann, T. (2017) · Steroids · doi:10.1016/j.steroids.2017.12.009 · Cited by 88
Cardiovascular Disease in South Asian Migrants
Fernando, E., Razak, F. A., Lear, S. A., & Anand, S. S. (2015) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2015.06.008 · Cited by 88
Self-citationGadgil, M. D., Anderson, C. A. M., Kandula, N. R., & Kanaya, A. M. (2013) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2013.09.021 · Cited by 88
Bhopal, R. S. (2013) · Diabetic Medicine · doi:10.1111/dme.12016 · Cited by 77
Grippo, P. J., Fitchev, P. S., Bentrem, D. J., Melstrom, L. G., Dangi-Garimella, S. Y., Krantz, S. B., Heiferman, M. J., Chung, C., Adrián, K., Cornwell, M. L., et al. (2012) · Gut · doi:10.1136/gutjnl-2011-300821 · Cited by 79
Self-citationBakker, L. E. H., van Schinkel, L. D., Guigas, B., Streefland, T. C. M., Jonker, J. T., van Klinken, J. B., van der Zon, G. C. M., Lamb, H. J., Smit, J. W. A., Pijl, H., et al. (2014) · Diabetes · doi:10.2337/db13-0696 · Cited by 77
Louis, F., Kitano, S., Mano, J. F., & Matsusaki, M. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.11.048 · Cited by 74
Association of Fat Density With Subclinical Atherosclerosis
Alvey, N. J., Pedley, A., Rosenquist, K. J., Massaro, J. M., O’Donnell, C. J., Hoffmann, U., & Fox, C. S. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.000788 · Cited by 70
Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study
The START Cohort Study Investigators, Anand, S. S., Vasudevan, A., Gupta, M., Morrison, K. M., Kurpad, A. V., Teo, K. K., & Srinivasan, K. (2013) · BMC Public Health · doi:10.1186/1471-2458-13-79 · Cited by 65
Self-citationHuman Brown Fat Radiodensity Indicates Underlying Tissue Composition and Systemic Metabolic Health
U-Din, M., Raiko, J. R. H., Saari, T., Saunavaara, V., Kudomi, N., Solin, O. H., Parkkola, R. K., Nuutila, P., & Virtanen, K. A. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2698 · Cited by 72
MECHANISMS IN ENDOCRINOLOGY: Pathogenesis of type 2 diabetes in South Asians
Bakker, L. E. H., Sleddering, M. A., Schoones, J. W., Meinders, A. E., & Jazet, I. M. (2013) · European Journal of Endocrinology · doi:10.1530/eje-13-0307 · Cited by 63
Eastwood, S. V., Tillin, T., Wright, A., Mayet, J., Godsland, I., Forouhi, N. G., Whincup, P., Hughes, A. D., & Chaturvedi, N. (2014) · Obesity · doi:10.1002/oby.20796 · Cited by 61
Eastwood, S. V., Tillin, T., Dehbi, H., Wright, A., Forouhi, N. G., Godsland, I. F., Whincup, P. H., Sattar, N. A., Hughes, A. D., & Chaturvedi, N. (2015) · Obesity · doi:10.1002/oby.20997 · Cited by 59
Monickaraj, F., Gokulakrishnan, K., Paramasivam, P., Chandrakumar, S., Anjana, R. M., Rajkumar, J., Mohan, V., & Balasubramanyam, M. (2012) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2012.07.097 · Cited by 61
Body Composition and Diabetes Risk in South Asians: Findings From the MASALA and MESA Studies
Flowers, E., Lin, F., Kandula, N. R., Allison, M., Carr, J. J., Ding, J., Shah, R. V., Liu, K., Herrington, D. M., & Kanaya, A. M. (2019) · Diabetes Care · doi:10.2337/dc18-1510 · Cited by 58
Kapoor, N., Jiwanmall, S. A., Nandyal, M. B., Kattula, D., Paravathareddy, S., Paul, T. V., Furler, J., Oldenburg, B. F., & Thomas, N. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s266277 · Cited by 49
The Role of Adiponectin in Cardiometabolic Diseases: Effects of Nutritional Interventions
López-Jaramillo, P. A. (2016) · Journal of Nutrition · doi:10.3945/jn.114.202432 · Cited by 49
Agarwala, A., Satish, P., Rifai, M. A., Mehta, A., Cainzos‐Achirica, M., Shah, N. S., Kanaya, A. M., Sharma, G. V., Dixon, D. L., Blumenthal, R. S., et al. (2023) · JACC Advances · doi:10.1016/j.jacadv.2023.100258 · Cited by 52
Diabetes and cardiometabolic risk in South Asian youth: A review
Wolf, R. M., Nagpal, M., & Magge, S. N. (2020) · Pediatric Diabetes · doi:10.1111/pedi.13078 · Cited by 61
Roh, E., Kim, K. M., Park, K. S., Kim, Y. J., Chun, E. J., Choi, S. H., Park, K. S., Jang, H. C., & Lim, S. K. (2018) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13447 · Cited by 47
Epidemiology of diabetes among South Asians in the United States: lessons from the MASALA study
Gujral, U. P., & Kanaya, A. M. (2020) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14530 · Cited by 57
Shah, R. V., Allison, M., Lima, J. A. C., Abbasi, S. A., Eisman, A. S., Lai, C., Jerosch‐Herold, M., Budoff, M. J., & Murthy, V. L. (2015) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2015.12.002 · Cited by 45
Rattarasarn, C. (2018) · Adipocyte · doi:10.1080/21623945.2018.1429784 · Cited by 47
A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes
Ito, M., Nagasawa, M., Omae, N., Tsunoda, M., Ishiyama, J., Ide, T., Akasaka, Y., & Murakami, K. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m031591 · Cited by 43
Kapoor, N., Lotfaliany, M., Sathish, T., Thankappan, K. R., Thomas, N., Furler, J., Oldenburg, B. F., & Tapp, R. J. (2020) · Journal of Nutritional Science · doi:10.1017/jns.2020.8 · Cited by 44
The BMI–adiposity conundrum in South Asian populations: need for further research
Kapoor, N., Furler, J., Paul, T. V., Thomas, N., & Oldenburg, B. F. (2019) · Journal of Biosocial Science · doi:10.1017/s0021932019000166 · Cited by 43
Sommer, C., Jenum, A. K., Waage, C. W., Mørkrid, K., Sletner, L., & Birkeland, K. I. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0060 · Cited by 43
Rashid, S., Sniderman, A. D., Melone, M., Brown, P. E., Otvos, J. D., Mente, A., Schulze, K. M., McQueen, M., Anand, S. S., & Yusuf, S. (2014) · European Journal of Preventive Cardiology · doi:10.1177/2047487314528461 · Cited by 41
Self-citationMetabolic Basis of Ethnic Differences in Diabetes Risk in Overweight and Obese Youth
Alderete, T. L., Toledo‐Corral, C. M., & Goran, M. I. (2014) · Current Diabetes Reports · doi:10.1007/s11892-013-0455-z · Cited by 41
South Asian Cardiovascular Disease & Cancer Risk: Genetics & Pathophysiology
Palaniappan, L. P., Garg, A., Enas, E. A., Lewis, H., Bari, S., Gulati, M., Flores, C., Mathur, A. K., Molina, C. R., Narula, J., et al. (2018) · Journal of Community Health · doi:10.1007/s10900-018-0527-8 · Cited by 45
U-Din, M., Ahmed, B. A., Syed, S. A., Ong, F. J., Oreskovich, S. M., Gunn, E., Surette, M. G., Punthakee, Z., Steinberg, G. R., & Morrison, K. M. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad604 · Cited by 41
Type 2 diabetes in South Asians
Misra, A., Sattar, N. A., Ghosh, A., Nassar, M., Jayawardena, R., & Gupta, R. (2025) · BMJ · doi:10.1136/bmj-2024-079801 · Cited by 40
Sai, E., Shimada, K., Yokoyama, T., Sato, S., Miyazaki, T., Hiki, M., Tamura, Y., Aoki, S., Watada, H., Kawamori, R., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061604 · Cited by 35
Body composition and risk factors for cardiovascular disease in global multi-ethnic populations
Carter, J. L., Abdullah, N., Bragg, F., Murad, N. A. A., Taylor, H., Fong, C. S., Lacey, B., Sherliker, P., Karpe, F., Mustafa, N., et al. (2023) · International Journal of Obesity · doi:10.1038/s41366-023-01339-9 · Cited by 34
Risk of Obesity-Related Cardiometabolic Complications in Special Populations: A Crisis in Asians
Abate, N. I., & Chandalia, M. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.01.046 · Cited by 34
Upadhyaya, S., Kadamkode, V., Mahammed, R., Doraiswamy, C., & Banerjee, G. (2013) · Adipocyte · doi:10.4161/adip.26553 · Cited by 33
Shajith Anoop, S., Misra, A., Bhatt, S. P., Gulati, S., Mahajan, H., & Prabakaran, G. (2017) · Journal of Diabetes Research · doi:10.1155/2017/2376016 · Cited by 31
Race/Ethnicity, Obesity, and Related Cardio-Metabolic Risk Factors: A Life-Course Perspective
Wahi, G., & Anand, S. S. (2013) · Current Cardiovascular Risk Reports · doi:10.1007/s12170-013-0329-6 · Cited by 32
Self-citationMcLaren, J. B., Gao, X., Ghouri, N., Freeman, D. J., Richardson, J., Sattar, N. A., & Gill, J. M. R. (2024) · Nature Metabolism · doi:10.1038/s42255-024-01101-z · Cited by 30
Sasaki, R., Yano, Y., Yasuma, T., Onishi, Y., Suzuki, T., Maruyama-Furuta, N., Gabazza, E. C., Sumida, Y., & Takei, Y. (2016) · Internal Medicine · doi:10.2169/internalmedicine.55.4100 · Cited by 27
ROSENBAUM, M. S., Fennoy, I., Accacha, S. D., Altshuler, L. A., Carey, D. E., Holleran, S., Rapaport, R., Shelov, S. P., Speiser, P., Ten, S., et al. (2013) · Obesity · doi:10.1002/oby.20483 · Cited by 26
Jain, A., Puri, R., & Nair, D. R. (2017) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000411 · Cited by 24
Adipocytes in Normal Tissue Biology
Ojha, S., Budge, H., & Symonds, M. E. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-386456-7.04408-7 · Cited by 27
Association between serum and adipose tissue resistin with dysglycemia in South Asian women
Wijetunge, S., Ratnayake, C., Kotakadeniya, H. M. S. R. B., Rosairo, S., Albracht‐Schulte, K., Ramalingam, L., Moustaïd‐Moussa, N., & Kalupahana, N. S. (2019) · Nutrition and Diabetes · doi:10.1038/s41387-019-0071-3 · Cited by 25
The Interplay Between Sex, Ethnicity, and Adipose Tissue Characteristics
Karastergiou, K. (2015) · Current Obesity Reports · doi:10.1007/s13679-015-0149-8 · Cited by 25
Endocannabinoid tone is higher in healthy lean South Asian than white Caucasian men
Kantae, V., Nahon, K. J., Straat, M. E., Bakker, L. E. H., Harms, A. C., van der Stelt, M., Hankemeier, T., Jazet, I. M., Boon, M. R., & Rensen, P. C. N. (2017) · Scientific Reports · doi:10.1038/s41598-017-07980-5 · Cited by 24
Mahadevan, M., Bose, M., Gawron, K. M., & Blumberg, R. (2023) · Healthcare · doi:10.3390/healthcare11050720 · Cited by 26
Stewart, C. P., Christian, P. S., Wu, L. S. F., LeClerq, S. C., Khatry, S. K., & West, K. P. (2013) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2013.0016 · Cited by 23
Relationship of Adipocyte Size with Adiposity and Metabolic Risk Factors in Asian Indians
Meena, V. P., Seenu, V., Sharma, M. C., Mallick, S., Bhalla, A. S., Gupta, N., Mohan, A., Guleria, R., Pandey, R. M., Luthra, K., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108421 · Cited by 24
Eng, P. C., Teo, A. E. D., Leow, M. K. S., Tai, E. S., & Khoo, C. M. (2025) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.16601 · Cited by 22
The Ethnoepidemiology of Obesity
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Self-citationShajith Anoop, S., Misra, A., Bhatt, S. P., Gulati, S., Pandey, R. M., & Mahajan, H. (2017) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2017-000393 · Cited by 21
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Boon, M. R., Bakker, L. E. H., van der Linden, R. A. D., van Ouwerkerk, A. F., de Goeje, P. L., Counotte, J., Jazet, I. M., & Rensen, P. C. N. (2015) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2014.1003634 · Cited by 20
Wulan, S. N., Westerterp, K., & Plasqui, G. (2014) · British Journal of Nutrition · doi:10.1017/s0007114514000014 · Cited by 30
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Thomas, P., Gallagher, M. T., & Xavier, G. D. S. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1275835 · Cited by 18
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Pope, B. D., Warren, C. R., Dahl, M. O., Pizza, C. V., Henze, D. E., Sinatra, N. R., Gonzalez, G. M., Chang, H., Liu, Q., Glieberman, A. L., et al. (2020) · Lab on a Chip · doi:10.1039/d0lc00508h · Cited by 19
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Mathur, R., Hull, S., Boomla, K., & Robson, J. P. (2012) · British Journal of General Practice · doi:10.3399/bjgp12x653642 · Cited by 16
Singla, R., Garg, A., Singla, S., & Gupta, Y. (2018) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/ijem.ijem_601_17 · Cited by 16
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Samaan, M. C., Anand, S. S., Sharma, A. M., Samjoo, I. A., & Tarnopolsky, M. A. (2015) · Scientific Reports · doi:10.1038/srep09154 · Cited by 15
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Metadata
- Authors
- Anand, S. S., Tarnopolsky, M. A., Rashid, S., Schulze, K. M., Desai, D., Mente, A., Rao, S., Yusuf, S., Gerstein, H. C., & Sharma, A. M.
- Affiliations
- Population Health Research Institute (CA)
- McMaster University (CA)
- University of Alberta (CA)
- Corresponding author
- Anand, Sonia S.
- ORCID
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2011-07-28
- Volume
- 6
- Issue
- 7
- Pages
- e22112
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3145635
- OpenAlex
- W2043632902
- Cited by
- 174
- References
- 36
- Citations by year
- 2026: 8 · 2025: 14 · 2024: 13 · 2023: 11 · 2022: 2 · 2021: 8 · 2020: 13 · 2019: 10 · 2018: 9 · 2017: 13 · 2016: 9 · 2015: 20 · 2014: 19 · 2013: 15 · 2012: 8
- FWCI
- 10.56
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Heart and Stroke Foundation of Canada
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- adipocyte hypertrophy, hepatic steatosis, South Asians, ethnic differences, body fat distribution, visceral adipose tissue, insulin resistance, adiponectin, HDL cholesterol, cardiovascular risk factors, body composition, lean muscle mass, waist-to-hip ratio, adipocyte size, metabolic risk factors, ethnic health disparities
- MeSH terms
- Adult, Cardiovascular Diseases, Ethnicity, Fatty Liver, Female, Humans, Insulin, Lipids, Male, Obesity, Risk Factors, Adipocytes, White People, Asian People, Waist-Hip Ratio, Adiponectin
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