Hypervirulent K. Pneumoniae Secretes More and More Active Iron-Acquisition Molecules than “Classical” K. Pneumoniae Thereby Enhancing its Virulence

Russo, Thomas A.; Shon, Alyssa S.; Beanan, Janet M.; Olson, Ruth; MacDonald, Ulrike; Pomakov, Alexander O.; Visitacion, Mark P.

doi:10.1371/journal.pone.0026734

Hypervirulent K. Pneumoniae Secretes More and More Active Iron-Acquisition Molecules than “Classical” K. Pneumoniae Thereby Enhancing its Virulence

Background A new hypervirulent (hypermucoviscous) clinical variant of Klebsiella pneumoniae (hvKP) has emerged over the last decade. Our goal is to identify new mechanisms, which increase the virulence hvKP compared to “classic” K. pneumoniae (cKP). Methodology/Principal Findings Various growth a…