The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.
Virulence Factors in Hypervirulent Klebsiella pneumoniae
Open accessAbstract
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae (cKP), with hypermucoviscosity and hypervirulence, causing community-acquired infections, including pyogenic liver abscess, pneumonia, meningitis, and endophthalmitis. It utilizes a battery of virulence factors for survival and pathogenesis, such as capsule, siderophores, lipopolysaccharide, fimbriae, outer membrane proteins, and type 6 secretion system, of which the former two are dominant. This review summarizes these hvKP-associated virulence factors in order to understand its molecular pathogenesis and shed light on new strategies to improve the prevention, diagnosis, and treatment of hvKP-causing infection.
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Cites
Klebsiella pneumoniae: Going on the Offense with a Strong Defense
Paczosa, M. K., & Mecsas, J. (2016) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00078-15 · Cited by 1,988
Siderophore-Based Iron Acquisition and Pathogen Control
Miethke, M., & Marahiel, M. A. (2007) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00012-07 · Cited by 1,774
Hypervirulent Klebsiella pneumoniae
Russo, T. A., & Marr, C. M. (2019) · Clinical Microbiology Reviews · doi:10.1128/cmr.00001-19 · Cited by 1,311
Hypervirulent (hypermucoviscous)Klebsiella pneumoniae: A new and dangerous breed
Shon, A. S., Bajwa, R. P. S., & Russo, T. A. (2013) · Virulence · doi:10.4161/viru.22718 · Cited by 1,171
Population genomics of Klebsiella pneumoniae
Wyres, K. L., Lam, M. M. C., & Holt, K. E. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0315-1 · Cited by 1,160
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Klebsiella pneumoniae liver abscess: a new invasive syndrome
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Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives
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Cited by
Klebsiella species: Taxonomy, hypervirulence and multidrug resistance
Dong, N., Yang, X., Chan, E. W.-C., Zhang, R., & Chen, S. (2022) · eBioMedicine · doi:10.1016/j.ebiom.2022.103998 · Cited by 313
Pu, D., Zhao, J., Chang, K., Zhuo, X., & Cao, B. (2023) · Science Bulletin · doi:10.1016/j.scib.2023.09.040 · Cited by 194
Neumann, B., Lippmann, N., Wendt, S., Karlas, T., Lübbert, C., Werner, G., Pfeifer, Y., & Schuster, C. F. (2022) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/s12941-022-00521-7 · Cited by 12
Metadata
- Authors
- Zhu, J., Wang, T., Chen, L., & Du, H.
- Venue
- Frontiers in Microbiology
- Publisher
- Frontiers Media SA
- Published
- 2021-04-08
- Volume
- 12
- Pages
- 642484-642484
- ISSN
- 1664-302X (ISSN-L)
- OpenAlex
- W3154090612
- Cited by
- 320
- References
- 149
- FWCI
- 25.49
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
