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Microbial Symbionts Accelerate Wound Healing via the Neuropeptide Hormone Oxytocin
Open accessAbstract
Wound healing capability is inextricably linked with diverse aspects of physical fitness ranging from recovery after minor injuries and surgery to diabetes and some types of cancer. Impact of the microbiome upon the mammalian wound healing process is poorly understood. We discover that supplementing the gut microbiome with lactic acid microbes in drinking water accelerates the wound-healing process to occur in half the time required for matched control animals. Further, we find that Lactobacillus reuteri enhances wound-healing properties through up-regulation of the neuropeptide hormone oxytocin, a factor integral in social bonding and reproduction, by a vagus nerve-mediated pathway. Bacteria-triggered oxytocin serves to activate host CD4+Foxp3+CD25+ immune T regulatory cells conveying transplantable wound healing capacity to naive Rag2-deficient animals. This study determined oxytocin to be a novel component of a multi-directional gut microbe-brain-immune axis, with wound-healing capability as a previously unrecognized output of this axis. We also provide experimental evidence to support long-standing medical traditions associating diet, social practices, and the immune system with efficient recovery after injury, sustained good health, and longevity.
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“Indeed, administration of L. reuteri, to mice resulted in an increase in the circulation levels and expression of oxytocin, which was associated with an increase in social behavior (Buffington et al., 2016;Poutahidis et al., 2013).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Poutahidis et al., 2013
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“Interestingly, the effects observed above are dependent on vagal signaling, which blunted the effects of Lactobacillus on host plasma and hypothalamic oxytocin [132,133].”
From Anxiety, depression, and the microbiome: A role for gut peptides (2018) · cites this paper as [132]
In the citing paper
“We and others have shown that L. reuteri increases oxytocin levels (Buffington et al., 2016; Poutahidis et al., 2013).”
From Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder (2019) · cites this paper as Poutahidis et al., 2013
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“We and others have previously provided correlational evidence that L. reuteri increases oxytocin levels (Buffington et al., 2016; Poutahidis et al., 2013)”
From Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder (2019) · cites this paper as Poutahidis et al., 2013
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Cites
Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992
Gurtner, G. C., Werner, S., Barrandon, Y., & Longaker, M. T. (2008) · Nature · doi:10.1038/nature07039 · Cited by 6,542
Singer, A. J., & Clark, R. A. F. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411006 · Cited by 6,106
Wound Healing--Aiming for Perfect Skin Regeneration
Martin, P. B. (1997) · Science · doi:10.1126/science.276.5309.75 · Cited by 4,842
Host-gut microbiota metabolic interactions
Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S. (2012) · Science · doi:10.1126/science.1223813 · Cited by 4,760
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572
Tumors: Wounds That Do Not Heal
Flier, J. S., Underhill, L. H., & Dvorak, H. F. (1986) · New England Journal of Medicine · doi:10.1056/nejm198612253152606 · Cited by 4,391 · cited 1×
“The processes of re-epithelialization and granulation tissue formation with collagen deposition and successive influx of different subsets of immune cells match the classical wound healing timeline previously described in C57BL/6 mice [33,48,56].”
BackgroundVagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
Borovikova, L. V., Ivanova, S., Zhang, M., Yang, H., Botchkina, G. I., Watkins, L. R., Wang, H., Abumrad, N., Eaton, J. W., & Tracey, K. J. (2000) · Nature · doi:10.1038/35013070 · Cited by 4,211
Interactions Between the Microbiota and the Immune System
Hooper, L. V., Littman, D. R., & Macpherson, A. J. (2012) · Science · doi:10.1126/science.1223490 · Cited by 4,173
Bravo, J. A., Forsythe, P., Chew, M. V., Escaravage, E., Savignac, H. M., Dinan, T. G., Bienenstock, J., & Cryan, J. F. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102999108 · Cited by 3,888
Flagged first, then by citations
Cited by
Sorted by citations
Items 201–300 of 310
Center Role of the Oxytocin-Secreting System in Neuroendocrine-Immune Network Revisited
Wang, Y. (2016) · Cited by 8
Denys, M. E., Kozlova, E. V., Liu, R., Bishay, A. E., Do, E. A., Piamthai, V., Korde, Y. V., Luna, C. N., Lam, A. A., Hsiao, A., et al. (2024) · Archives of Toxicology · doi:10.1007/s00204-024-03882-4 · Cited by 9
Martin, E. M., Xue, J., & Smith, C. J. W. (2025) · Behavioural Brain Research · doi:10.1016/j.bbr.2025.115723 · Cited by 7
Wang, A. Y. L., Aviña, A. E., Liu, Y., & Kao, H. (2025) · Burns & Trauma · doi:10.1093/burnst/tkaf068 · Cited by 8
The buzz within: the role of the gut microbiome in honeybee social behavior
Nguyen, J. B., Marshall, C. W., & Cook, C. N. (2024) · Journal of Experimental Biology · doi:10.1242/jeb.246400 · Cited by 7
Sapkota, R., Nakatsu, C. H., & Scharf, M. E. (2021) · Journal of Experimental Biology · doi:10.1242/jeb.242553 · Cited by 7
The Impact of Kefir on Epidermal Water Homeostasis in Healthy Human Skin
Alves, E., Gregório, J., Rijo, P. M., Rosado, C., & Rodrigues, L. M. (2022) · Life · doi:10.3390/life12071075 · Cited by 7
ENVOLVIMENTO DA FLORA INTESTINAL NA MODULAÇÃO DE DOENÇAS PSIQUIÁTRICAS
Lach, G., Morais, L. H., Costa, A. P., & Hoeller, A. A. (2017) · VITTALLE - Revista de Ciências da Saúde · doi:10.14295/vittalle.v29i1.6413 · Cited by 12
Microbiota and behaviour: visiting the sins of the mother
Forsythe, P., & Bienenstock, J. (2016) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2016.122 · Cited by 7
Leckman, J. F. (2014) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12259 · Cited by 9
Molinas-Vera, M., Ferreira-Sanabria, G., Peña, P., & Sandoval-Espínola, W. J. (2024) · Gut Microbes Reports · doi:10.1080/29933935.2024.2332988 · Cited by 7
Does the Maternal Gut Microbiome Influence the Outcome of Perinatal Asphyxia?
Morozan, V.-P., Ionescu, M.-I., Zahiu, C. D. M., Catrina, A. M., Racoviță, A., Chirilă, A.-T., Dogaru, I.-A., Ciotei, C., Pîrcălăbioru, G. G., & Zăgrean, A. (2025) · Antioxidants · doi:10.3390/antiox14091134 · Cited by 8
Immunomodulatory functions of microorganisms in tissue regenerative healing
Wang, M., Liu, H., Huang, M., Huang, Y., Ming, Y., Chen, W., Chen, Y., Tang, Z., & Jia, B. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.10.007 · Cited by 6
Microbial Muses: Threads of Our Inner Wisdom
Erdman, S. E. (2021) · Challenges · doi:10.3390/challe12010010 · Cited by 6
Human gut microbiota and endocrinology: paradigm shift from genome to its regulation
Lamaudière, M. T. F., Turner, M. C., Arasaradnam, R. P., & Morozov, I. Y. (2023) · Journal of Endocrinology · doi:10.1530/joe-23-0348 · Cited by 7
Erdman, S. E. (2016) · Aging · doi:10.18632/aging.101154 · Cited by 6
Bubnov, R. V., & NIa, S. (2018) · Preprints.org · doi:10.20944/preprints201809.0185.v1 · Cited by 6
What Surgeon Should Know about Probiotics
Kotzampassi, K. E. (2022) · Nutrients · doi:10.3390/nu14204374 · Cited by 5
Healing with Love: Oxytocin Accelerates Oral Ulcer Recovery by Reducing Inflammation
Zeytinoğlu, M., Çınaroğlu, O. S., Bora, E. S., & Erbaş, O. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14082667 · Cited by 5
The influence of intestinal microbiome on wound healing and infection
Krezalek, M. A., & Alverdy, J. C. (2017) · Seminars in Colon and Rectal Surgery · doi:10.1053/j.scrs.2017.09.004 · Cited by 5
Gut microbiota-derived metabolites in keloid and hypertrophic scarring
Jin, J., & ZHENG, Z. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1644758 · Cited by 6
Benlakehal, R., Gaetano, A., Charlet, R., Bouwalerh, H., Cogez, V., Harduin‐Lepers, A., Sendid, B., Nicoletti, F., Maccari, S., & Morley‐Fletcher, S. (2025) · Scientific Reports · doi:10.1038/s41598-025-05848-7 · Cited by 4
Consuming cholera toxin counteracts age-associated obesity
Varian, B. J., Poutahidis, T., Haner, G., Hardas, A., Lau, V., & Erdman, S. E. (2019) · Oncotarget · doi:10.18632/oncotarget.27137 · Cited by 4
Moghaddam, S. S., & Neff, A. (2021) · Oral and Maxillofacial Surgery · doi:10.1007/s10006-021-01017-y · Cited by 4
Azteca ants repair damage to their Cecropia host plants
Wcislo, A., Graham, X., Stevens, S., Toppe, J. E., Wcislo, L., & Wcislo, W. T. (2021) · Journal of Hymenoptera Research · doi:10.3897/jhr.88.75855 · Cited by 4
The intertwining of oxytocin's effects on social affiliation and inflammation
Kingsbury, M. A. (2024) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2024.100239 · Cited by 5
From Gut to Reproductive Health: Exploring Microbiome Interactions and Future Interventions
Singh, S., Kriti, M., Sharma, P., Pal, N., Sarma, D. K., Verma, V., Tiwari, R. R., & Kumar, M. (2025) · Reproductive Sciences · doi:10.1007/s43032-025-02001-7 · Cited by 3
[Research progress on the mechanisms of probiotics promoting wound healing].
Dong, J., Wang, X., Bai, G., & Wang, D. (2024) · PubMed Central · doi:10.7507/1001-5515.202208003 · Cited by 3
The Perinatal Microbiota-Gut-Brain Axis: Implications for Postpartum Depression
Armbruster, M., & Forsythe, P. (2025) · NeuroImmunoModulation · doi:10.1159/000543691 · Cited by 6
Wang, R., Liu, G., Chen, H., Hou, H., & Hu, Q. (2025) · Neuroscience Letters · doi:10.1016/j.neulet.2025.138198 · Cited by 3
Vasopressin and Oxytocin Secretion by Microorganisms
Natochin, Y. V., Орлова, О. Г., Рыбальченко, О. В., & Ei, S. (2022) · Microbiology · doi:10.1134/s0026261721060102 · Cited by 3
Iatrou, A. M., Michailidou, S., Papadopoulos, G. Α., Afaloniati, H., Lagou, M. K., Kiritsi, M., Argiriou, A., Angelopoulou, K., Poutahidis, T., & Fortomaris, P. D. (2023) · Animals · doi:10.3390/ani13020190 · Cited by 5
Lakritz, J. R., Poutahidis, T., Levkovich, T., Varian, B. J., Ibrahim, Y. M., Chatzigiagkos, A., Mirabal, S., Alm, E. J., & Erdman, S. E. (2014) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 3
TRPV1, Nrf2, and COVID-19: Could Oxytocin Have a Beneficial Role to Play?
Diep, P.-T. (2022) · International Archives of Allergy and Immunology · doi:10.1159/000521246 · Cited by 3
Piñera-Moreno, R., Reyes‐López, F. E., Goldstein, M., Santillán-Araneda, M. J., Robles-Planells, B., Arancibia-Carvallo, C., Vallejos‐Vidal, E., Cuesta, A., Esteban, M. Á., & Tort, L. (2024) · Animals · doi:10.3390/ani14121815 · Cited by 2
Introduction to microbiomes in health and diseases
Agrawal, P., Mendhey, P., Kumar, R., Patel, S., Kaushik, P. K., Dadsena, A., & Kumar, S. (2025) · International review of cytology · doi:10.1016/bs.ircmb.2024.12.010 · Cited by 2
The cell’s autonomous response window for advanced healing
Feoli, E., Redondo, G. M., Flores, J. S., & Jara, D. P. (2025) · Discover Medicine · doi:10.1007/s44337-025-00478-4 · Cited by 3
Microbes in regenerative medicine: A narrative review
Varaganti, V., Avr, V., Vedanth, N. P., Pusuluri, R. C., Panniru, A. C., Potluri, S., & Kandi, V. (2025) · Regenerative medicine reports . · doi:10.4103/regenmed.regenmed-d-25-00026 · Cited by 2
Zhang, X., Dong, T. S., Gee, G. C., Kilpatrick, L. A., Beltrán‐Sánchez, H., Wang, M. C., Vaughan, A., & Church, A. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2566978 · Cited by 2
Neurocosmetics or Hype? Psychobiotic Potential of Strain-Specific Cosmeceuticals
Menni, A.-E., Theodorou, H., Tzikos, G., Stavrou, G., Theodorou, I. M., Semertzidou, E., Venieri, J., Ioannidis, A., Shrewsbury, A. D., & Kotzampassi, K. E. (2026) · Nutrients · doi:10.3390/nu18050817 · Cited by 2
Yu, K., & Chen, Z. (2021) · PubMed Central · doi:10.11817/j.issn.1672-7347.2021.200569 · Cited by 2
The Microbiota and the Relationship with Colorectal Cancer: Surgical Complications—A Review
Michire, A., Anghel, R. M., Draghia, P. M., Burlacu, M. G., Georgescu, T. F., Georgescu, D. E., Balcangiu‐Stroescu, A.-E., Văcăroiu, I. A., Barbu, M. A., & Gaube, A. (2022) · Gastrointestinal Disorders · doi:10.3390/gidisord4020008 · Cited by 2
Qiao, X., Kong, K., Liu, T., Jia, Y., Fang, J., & Zhang, X. (2023) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530323666230511140514 · Cited by 2
Erdman, S. E. (2023) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2023.100212 · Cited by 2
Łoniewski, I., Banasiewicz, T., Sieńko, J., Skonieczna‐Żydecka, K., & Stachowska, E. (2024) · Gastroenterology Review · doi:10.5114/pg.2024.145833 · Cited by 5
Immunomodulatory effect of nisin loaded with chitosan nanogel in ulcerative colitis rat model
Lorestanizadeh, G., Arasteh, J., Ardani, G. S., & Mehrjo, H. (2025) · The Journal of Basic and Applied Zoology · doi:10.1186/s41936-025-00438-5 · Cited by 2
Probiotics in the gut-skin axis – the case of kefir
Alves, E., Rijo, P. M., Rodrigues, L. M., & Rosado, C. (2021) · Biomedical and Biopharmaceutical Research · doi:10.19277/bbr.18.2.261 · Cited by 2
Barbotin, A., Giacobini, P., & Prévot, V. (2016) · médecine/sciences · doi:10.1051/medsci/20163211006 · Cited by 2
Rola mikrobiomu jelitowego w funkcjonowaniu układu nerwowego
Wierzchanowska, W. M., & Iwanicki, T. (2020) · Kosmos · doi:10.36921/kos.2020_2576 · Cited by 3
Could oxytocin reduce autoimmune disease in COVID-19?
Diep, P.-T., & de Kok, V. (2021) · Autoimmunity Reviews · doi:10.1016/j.autrev.2021.102994 · Cited by 2
Microbes and healthful longevity
Erdman, S. E. (2016) · Aging · doi:10.18632/aging.100969 · Cited by 2
Gut Microbiome Production and Modulation of Hormones That Influence Host Skin HealthPreprint
Maguire, M., & Maguire, G. (2020) · Preprints.org · doi:10.20944/preprints202003.0293.v1 · Cited by 2
Prior Antibiotic Exposure Is Associated With Reoperation After Elective Non-colorectal Surgery
Guidry, C. A., Medvecz, A. J., Adams, R. C., Dennis, B. M., Eastham, S. C., Guillamondegui, O. D., Gunter, O. L., Peetz, A. B., Thompson, C. M., Gondek, S. P., et al. (2022) · The American Surgeon · doi:10.1177/00031348221109812 · Cited by 1
Bioelectronic Devices for Targeted Drug Delivery and Monitoring of Microbial Electrogenesis
Roy, A. (2023) · Linköping studies in science and technology. Dissertations · doi:10.3384/9789180751551 · Cited by 1
Influence of gut microbiota on chronic pain syndrome
Bofanova, N. S., & Khanfar, Y. A. (2023) · Russian Journal of Pain · doi:10.17116/pain20232102150 · Cited by 1
Modulatory effects of Kratom extract on the gut microbiota of rats: implications for health
Thongsepee, N., Amonyingcharoen, S., Chamod, P., Himakhun, W., Sangpairoj, K., Martviset, P., Chantree, P., & Sornchuer, P. (2025) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-025-04836-8 · Cited by 1
Hazani, R., Weller, A., Turjeman, S., Sharon, E., Saleev, N., Moadi, L., Elliott, E., Bartal, I. B.-A., & Koren, O. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.06.023 · Cited by 1
Dynamic changes of gut and skin microbiota in pancreatic cancer-induced skin injury
Yao, S., Yan, X., Chen, H., Lei, S., Huang, J., Guo, K., & Yu, Z. P. (2025) · BMC Microbiology · doi:10.1186/s12866-025-04068-3 · Cited by 1
AexB is an aromatic amino acid exporter that functions as a metabolic safety valve
Everett, B. A., & Prindle, A. B. (2026) · mBio · doi:10.1128/mbio.00231-26 · Cited by 1
Immune roles of canonically non-immune cells in biomaterials response
Stelzel, J. L., McKnight, I., Greco, A. H., Hernandez, J. L., Huang, I., Erb, C. J., Wilson, D. S., Mao, H., & Doloff, J. C. (2026) · Cell Biomaterials · doi:10.1016/j.celbio.2026.100463 · Cited by 1
Microbes, Oxytocin, and Healthful longevity
Erdman, S. E. (2014) · Journal of Probiotics & Health · doi:10.4172/2329-8901.1000117 · Cited by 1
Oxytocin and secretin receptors – implications for dry eye syndrome and ocular pain
Lopez, J. B., Chang, C.-C. J., Kuo, Y., Chan, M. F., & Winn, B. J. (2022) · Frontiers in Ophthalmology · doi:10.3389/fopht.2022.948481 · Cited by 1
SARS-CoV-2 Interacts with Mucosal Dysbiosis to Cause the Wide Range of Disease Seen in Covid-19
Morris, J. A., Shepherd, R. F., P-T, D., Gatheral, T. L., Wray, M., & Rigby, R. J. (2022) · Austin Journal of Pulmonary and Respiratory Medicine · doi:10.26420/austinjpulmrespirmed.2022.1086 · Cited by 1
The Human-Animal Bond and Its Influence on Surgical Recovery in Pets
Liu, W. Y., & Xuan, J. (2024) · International Journal of Molecular Veterinary Research · doi:10.5376/ijmvr.2024.14.0011 · Cited by 1
Philosophy of Nutrition: Past-Future Nutrition
Meral, G. (2018) · IntechOpen eBooks · doi:10.5772/intechopen.80726 · Cited by 1
Walsham, A. D. S. (2016) · UEA Digital Repository (University of East Anglia) · Cited by 1
Understanding Developmental Psychopathology: How Useful Are Evolutionary Perspectives?
Leckman, J. F. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy204 · Cited by 1
Schmitt, L., Smith, E. G., Pedapati, E. V., Horn, P. S., Will, M., Lamy, M., Barber, L., Trebley, J., Meyer, K., Heiman, M. L., et al. (2022) · medRxiv · doi:10.1101/2022.11.14.22281882 · Cited by 1
Enhanced tameness by Limosilactobacillus reuteri from gut microbiota of selectively bred micePreprint
Biswa, B. B., Mori, H., Toyoda, A., Kurokawa, K., & Koide, T. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.11.584526 · Cited by 1
Shonka, S., Ford, C., & Hylin, M. J. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.30.651517 · Cited by 1
Counterinsurgency Doctrine Applied to Infectious DiseasePreprint
Kirkup, B. C. (2014) · doi:10.7287/peerj.preprints.236v1
Oxytocin, a missing link of the gut-brain axis between probiotics and chronic migraine?
Kwong, K. K., & Chan, S. (2016) · Beneficial Microbes · doi:10.3920/bm2016.x003
Microbes in the Treatment of Diabetes and Its Complications
Narumanchi, S., Mysore, Y., & Haridas, N. (2018) · Springer eBooks · doi:10.1007/978-981-10-7140-9_18
Mechanisms of the natural defenses of hosts to infection
Ov, B. (2019) · Вестник Российской академии наук · doi:10.31857/s0869-5873898844-850
Natural Mechanisms that Underlie the Defense of Host Organisms against Infections
Ov, B. (2019) · Herald of the Russian Academy of Sciences · doi:10.1134/s1019331619040014
The Microbiome, Probiotics, and Prebiotics
Fardin, S., & Keri, J. E. (2021) · Springer eBooks · doi:10.1007/978-3-030-58954-7_1
Gut microbiota and its impact on neuropsychiatric disorders
Wójcik, M., Dąbrowska, J., Bator, D., & Milanowska, J. (2020) · Journal of Education Health and Sport · doi:10.12775/jehs.2020.10.08.032
Einsatz von Probiotika in der Therapie parodontaler Erkrankungen
Jockel‐Schneider, Y., Schlagenhauf, U., & Rehder, J. (2021) · ZWR - Das Deutsche Zahnärzteblatt · doi:10.1055/a-1473-0008
Microbiome-Gut-Brain Interactions in Neurodevelopmental Disorders: Focus on Autism and Schizophrenia
Sandhu, K. V., Sherwin, E., Dinan, T. G., & Cryan, J. F. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108539623.014
Borenstein, E., & Muller, E. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732223689.793566912
Revisiting ‘what causes cancer?’
(2017) · Cancer Studies and Therapeutics · doi:10.31038/cst.2017211
Influence of the Gut Microbiota on Neuroendocrine-Immune Interactions
Bailey, M. T. (2023) · Masterclass in neuroendocrinology · doi:10.1007/978-3-031-21358-8_12
Lactobacilli and Klebsiella: Two Opposites in the Fight for Human Health
Shaposhnikov, L. A., Tishkov, V. I., & POMETUN, A. A. (2024) · Biochemistry (Moscow) · doi:10.1134/s0006297924140050
The Microbiome and the Entropy Paradox: An Evolutionary Perspective
Morris, J. A., Rigby, R. J., Wray, M., & Taylor, A. M. (2024) · Food & Nutrition Journal · doi:10.29011/2575-7091.100194
The Goldilocks Zone of Healing An unexploited resource for advanced healingPreprint
Feoli, E., Redondo, G. M., Flores, J. S., & Jara, D. P. (2024) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/zxcm6
Nogueira-Vale, E. (2024) · Springer eBooks · doi:10.1007/978-3-031-59038-2_4
Gut Microbiota, Breast Cancer, and Neoadjuvant Therapy
夏, 晨. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.153606
Ov, B., Nb, P., Timokhina, T. V., Костоломова, Е. Г., Paromova, Y. I., Ev, I., Polyanskih, E. D., & Markov, A. A. (2025) · Medical Immunology (Russia) · doi:10.15789/1563-0625-pon-2962
Xu, X., Bao, H., Chu, L., Yang, B., Han, B. X., Hao bo, L. I., Gaiha, L., Li, X., Er, D., & Bayin, J. (2025) · Research Square · doi:10.21203/rs.3.rs-8192945/v1
Kong, X., Liu, J., Li, J., Kwong, K. K., Koh, M., Sukijthamapan, P., Guo, J. J., Sun, Z. J., & Song, Y. (2019) · Research Square · doi:10.21203/rs.2.260/v1
Evenepoel, M., Daniëls, N., Moerkerke, M., Prinsen, J., Steyaert, J. G., Boets, B., Joossens, M., & Alaerts, K. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-03964-0
Zhang, F., Xu, W., Zeng, R., Chen, J., & Huang, J. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2649440
Microbiote intestinal, cancer du sein et métabolisme lipidique
Luu, T. H. (2018) · theses.fr (ABES) · doi:10.70675/5a95efcbzc6e9z41b8z84a5z058eda043638
The oxytocinergic descending control of pain and its modulation by neonatal maternal separation
Melchior, M. (2018) · theses.fr (ABES) · doi:10.70675/368c73c0ze731z4b57zb52cz8f31049fb33c
Bermudez-Martin, P. (2020) · theses.fr (ABES) · doi:10.70675/d0d223ffzbc0ez44d9z8475z153f265e94f5
Evenepoel, M., Tuerlinckx, E., Derrien, M., Moerkerke, M., Prinsen, J., Vila, A. V., Steyaert, J. G., Daniëls, N., Boets, B., Raes, J., et al. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.106579
Saloi, D., Zaman, A., Saha, D., Mehta, P., Das, T., & Das, B. K. (2026) · Tissue and Cell · doi:10.1016/j.tice.2026.103534
Neuroendocrine Pathways in Skin Health and Homeostasis: A Systematic Review
Kream, E. J., Golpanian, R. S., Hosking, A., Boen, M., & Fabi, S. G. (2026) · Journal of Dermatology Research · doi:10.46889/jdr.2026.7119
Dai, W., Jahangir, M., Li, T., & Guo, W.-J. (2026) · BMC Microbiology · doi:10.1186/s12866-026-05287-y
Metadata
- Authors
- Poutahidis, T., Kearney, S. M., Levkovich, T., Qi, P., Varian, B. J., Lakritz, J. R., Ibrahim, Y. M., Chatzigiagkos, A., Alm, E. J., & Erdman, S. E.
- Affiliations
- Aristotle University of Thessaloniki (GR)
- Massachusetts Institute of Technology (US)
- Broad Institute (US)
- Corresponding author
- Erdman, Susan E.
- ORCID
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2013-10-30
- Volume
- 8
- Issue
- 10
- Pages
- e78898
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3813596
- OpenAlex
- W2068527256
- Cited by
- 310
- References
- 85
- Citations by year
- 2026: 19 · 2025: 29 · 2024: 33 · 2023: 25 · 2022: 31 · 2021: 32 · 2020: 31 · 2019: 21 · 2018: 22 · 2017: 18 · 2016: 24 · 2015: 10 · 2014: 14 · 2013: 1
- FWCI
- 17.43
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by)
- Figshare (submittedVersion, cc-by)
- Funders
- National Institutes of Health
- National Cancer Institute (U01CA164337, R01CA108854)
- National Institute of Environmental Health Sciences (P30ES002109)
- Topics
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- wound healing, gut microbiota, Lactobacillus reuteri, oxytocin, vagus nerve, regulatory T cells, gut-brain-immune axis, lactic acid bacteria, drinking water supplementation, microbial symbionts
- MeSH terms
- Animals, Collagen, DNA-Binding Proteins, Female, Oxytocin, Symbiosis, Time Factors, Wound Healing, CD4-Positive T-Lymphocytes, Up-Regulation, Mice, Limosilactobacillus reuteri, Drinking Water
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