Molecular Epidemiology and Antimicrobial Susceptibility of Clinical Staphylococcus aureus from Healthcare Institutions in Ghana

Egyir, Beverly; Guardabassi, Luca; Sørum, Marit; Nielsen, Søren Saxmose; Kolekang, Augusta; Frimpong, Enoch; Addo, Kennedy Kwasi; Newman, Mercy Jemima; Larsen, Anders Rhod

doi:10.1371/journal.pone.0089716

Cited by 108Antimicrobial Resistance in StaphylococcusAntibiotic Use and ResistanceAntibiotic Resistance in Bacteria

Molecular Epidemiology and Antimicrobial Susceptibility of Clinical Staphylococcus aureus from Healthcare Institutions in Ghana

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Egyir, Beverly, Guardabassi, Luca, Sørum, Marit, Nielsen, Søren Saxmose, Kolekang, Augusta, Frimpong, Enoch, Addo, Kennedy Kwasi, Newman, Mercy Jemima +1 more·2014·PLoS ONE

DOI 10.1371/journal.pone.0089716PMC PMC3934920

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Abstract

The objective of this study was to determine the antimicrobial susceptibility patterns and clonal diversity of clinical Staphylococcus aureus isolates from Ghana. A total of 308 S. aureus isolates from six healthcare institutions located across Northern, Central and Southern Ghana were characterized by antibiotyping, spa typing and PCR detection of Panton Valentine leukocin (PVL) genes. Methicillin-resistant S. aureus (MRSA) were confirmed by PCR detection of mecA gene and further characterized by SCCmec and multi-locus sequence typing (MLST). The prevalence of antimicrobial resistance was below 5% for all agents tested except for penicillin (97%), tetracycline (42%) and erythromycin (6%). Ninety-one spa types were found, with t355 (ST152, 19%), t084 (ST15, 12%) and t314 (ST121, 6%) being the most frequent types. Based on established associations between spa and MLST types, isolates were assigned to 16 clonal complexes (CCs): CC152 (n = 78), CC15 (n = 57), CC121 (n = 39), CC8 (n = 36), CC5 (n = 33), CC1 (n = 29), CC45 (n = 9), CC88 (n = 8), CC30 (n = 4), CC9 (n = 3), CC25 (n = 2), CC97 (n = 2) CC20 (n = 2), CC707 (n = 2), CC7 (n = 3) and CC522 (n = 1). Most isolates (60%) were PVL-positive, especially those belonging to ST152, ST121, ST5, ST15, ST1, ST8, and ST88. Nine (3%) isolates were MRSA belonging to seven distinct clones: ST88-IV (n = 2), ST250-I (n = 2), ST8-IV (n = 1), ST72-V (n = 1), ST789-IV (n = 1), ST2021-V (n = 1), and ST239-III (n = 1). The study confirmed a high frequency of PVL-positive S. aureus in Africa, low prevalence of antimicrobial resistance and high diversity of MRSA lineages in Ghana compared to developed countries and other African countries. The detection of known pandemic MRSA clones in the absence of routine MRSA identification in most Ghanaian clinical microbiology laboratories calls for capacity building to strengthen surveillance and prevent spread of these clones.

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Community and healthcare-associated MRSA has been reported in most countries including Kenya, Uganda, Nigeria, South Africa, Ghana, Mozambique, Ethiopia, and Tanzania, with MRSA prevalence ranging from 1.25% to 53.4%.
“Nevertheless, community and healthcare-associated MRSA has been reported in most countries, including Kenya, Uganda, Nigeria, South Africa, Ghana, Mozambique, Ethiopia, and Tanzania, where the MRSA prevalence ranges from 1.25% to 53.4%.[157][158][159][160][161][162][163][164]”
From Antimicrobial Resistance Rates and Surveillance in Sub-Saharan Africa: Where Are We Now? (2022) · cites this paper as [159]
The Discussion reports MRSA in Ghanaian clinical isolates at 3% prevalence, within the cited range, and mentions MRSA reports from other African countries. This paper does not establish the stated 1.25%–53.4% range or distinguish community-associated from healthcare-associated cases in its Ghanaian sample. (LLM, conf=0.84)
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Madzgalla, S., Syed, M. A., Khan, M. A., Rehman, S. S., Müller, E., Reißig, A., Ehricht, R., & Monecke, S. (2016) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-016-2695-8 · Cited by 37 · see citing works
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Hogan, B., Rakotozandrindrainy, R., Al‐Emran, H. M., Dekker, D. M., Hahn, A., Jaeger, A., Poppert, S., Frickmann, H., Hagen, R. M., Micheel, V., et al. (2016) · BMC Infectious Diseases · doi:10.1186/s12879-016-1733-6 · Cited by 36 · see citing works
Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound treatment centres in Ghana
Kpeli, G. S., Otchere, I. D., Lamelas, A., Buultjens, A. H., Bulach, D., Baines, S. L., Seemann, T., Giulieri, S. G., Nakobu, Z., Aboagye, S. Y., et al. (2016) · New Microbes and New Infections · doi:10.1016/j.nmni.2016.07.001 · Cited by 35 · see citing works
Colonization of HIV-Infected Children with Methicillin-Resistant Staphylococcus aureus
Donkor, E. S., Kotey, F. C. N., Dayie, N. T. K. D., Duodu, S., Tetteh‐Quarcoo, P. B., Osei, M., & Tette, E. M. A. (2019) · Pathogens · doi:10.3390/pathogens8010035 · Cited by 34 · see citing works
Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana
Kpeli, G. S., Buultjens, A. H., Giulieri, S. G., Owusu-Mireku, E., Aboagye, S. Y., Baines, S. L., Seemann, T., Bulach, D., da Silva, A. G., Monk, I. R., et al. (2017) · PeerJ · doi:10.7717/peerj.3047 · Cited by 34 · see citing works
Epidemiology of Staphylococcus aureus in a burn unit of a tertiary care center in Ghana
Amissah, N. A., van Dam, L., Ablordey, A. S., Ampomah, O.-W., Prah, I., Tetteh, C. S., van der Werf, T. S., Friedrich, A. W., Rossen, J. W. A., van Dijl, J. M., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181072 · Cited by 33 · see citing works
Antimicrobial Resistance and Virulence of Methicillin-Resistant Staphylococcus aureus from Human, Chicken and Environmental Samples within Live Bird Markets in Three Nigerian Cities
Ogundipe, F. O., Ojo, O. E., Feßler, A. T., Hanke, D., Awoyomi, O. J., Ojo, D. A., Akintokun, A. K., Schwarz, Š., & Maurischat, S. (2020) · Antibiotics · doi:10.3390/antibiotics9090588 · Cited by 33 · see citing works
Genetic Diversity of Staphylococcus aureus in Buruli Ulcer
Amissah, N. A., Glasner, C., Ablordey, A. S., Tetteh, C. S., Kotey, N. K., Prah, I., van der Werf, T. S., Rossen, J. W. A., van Dijl, J. M., & Stienstra, Y. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003421 · Cited by 31 · see citing works
Methicillin-resistant Staphylococcus aureus strains from Ghana include USA300
Egyir, B., Guardabassi, L., Monecke, S., Addo, K. K., Newman, M. J., & Larsen, A. R. (2014) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2014.11.006 · Cited by 31 · see citing works
Self-citation
COVID-19 pandemic and antimicrobial resistance: Another call to strengthen laboratory diagnostic capacity in Africa
Egyir, B., Obeng‐Nkrumah, N., & Kyei, G. B. (2020) · African Journal of Laboratory Medicine · doi:10.4102/ajlm.v9i1.1302 · Cited by 31 · see citing works
Self-citation
Staphylococcus aureus in former Portuguese colonies from Africa and the Far East: missing data to help fill the world map
Conceição, T., Coelho, C., Silva, I. S., de LENCASTRE, H., & Aires-de-Sousa, M. (2015) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2015.05.010 · Cited by 30 · see citing works
Association of virulence genes with mecA gene in Staphylococcus aureus isolates from Tertiary Hospitals in Nigeria
Alli, O. A. T., Ogbolu, D. O., Shittu, A. O., Okorie, A., Akinola, J., & Daniel, J. (2015) · Indian Journal of Pathology and Microbiology · doi:10.4103/0377-4929.168875 · Cited by 29 · see citing works
Prevalence and diversity of Staphylococcus aureus in the Zambian dairy value chain: A public health concern
Phiri, B. S. J., Hang’ombe, B. M., Mulenga, E., Mubanga, M., Maurischat, S., Wichmann-Schauer, H., Schaarschmidt, S., & Fetsch, A. (2022) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2022.109737 · Cited by 28 · see citing works
Causative agents and antimicrobial resistance patterns of human skin and soft tissue infections in Bagamoyo, Tanzania
Kazimoto, T., Abdulla, S., Bategereza, L., Juma, O. A., Mhimbira, F., Weisser, M., Utzinger, J., von Müller, L., & Becker, S. L. (2018) · Acta Tropica · doi:10.1016/j.actatropica.2018.07.007 · Cited by 27 · see citing works
Whole-genome sequence profiling of antibiotic-resistant Staphylococcus aureus isolates from livestock and farm attendants in Ghana
Egyir, B., Hadjirin, N. F., Gupta, S., Owusu, F. A., Agbodzi, B., ADOGLA-BESSA, T., Addo, K. K., Stegger, M., Larsen, A. R., & Holmes, M. A. (2020) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2020.03.029 · Cited by 25 · see citing works
Self-citation
Pigs as a potential source of emerging livestock-associated Staphylococcus aureus in Africa: a systematic review
Samutela, M., Kwenda, G., Simulundu, E., Nkhoma, P., Higashi, H., Frey, A. M., Bates, M., & Hang’ombe, B. M. (2021) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2021.06.023 · Cited by 25 · see citing works
Molecular epidemiology of Staphylococcus aureus from Lambaréné, Gabon
Okuda, K. V., Toepfner, N., Alabi, A. S., Arnold, B., Bélard, S., Falke, U., Menschner, L., Monecke, S., Ruppelt-Lorz, A., & Berner, R. (2016) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-016-2748-z · Cited by 23 · see citing works
Molecular Characterization and Pathogenicity of Staphylococcus aureus Isolated from Benin-City, Nigeria
Obasuyi, O., McClure, J., Oronsaye, F. E., Akerele, J. O., Conly, J. M., & Zhang, K. (2020) · Microorganisms · doi:10.3390/microorganisms8060912 · Cited by 23 · see citing works
Molecular Characterization of Staphylococcus aureus Isolates Transmitted between Patients with Buruli Ulcer
Amissah, N. A., Chlebowicz, M. A., Ablordey, A. S., Sabat, A. J., Tetteh, C. S., Prah, I., van der Werf, T. S., Friedrich, A. W., van Dijl, J. M., Rossen, J. W. A., et al. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004049 · Cited by 22 · see citing works
Molecular Characterization of Staphylococcus aureus Isolated from Human and Food Samples in Northern Algeria
Achek, R., El‐Adawy, H., Hotzel, H., Hendam, A., Tomaso, H., Ehricht, R., Neubauer, H., Nabi, I., Hamdi, T. M., & Monecke, S. (2021) · Pathogens · doi:10.3390/pathogens10101276 · Cited by 20 · see citing works
Molecular characterisation of methicillin-resistant Staphylococcus aureus (MRSA) isolated at a large referral hospital in Zambia.
Samutela, M., Kalonda, A., Mwansa, J. C. L., Lukwesa‐Musyani, C., Mwaba, J., Mumbula, E. M., Mwenya, D., Simulundu, E., & Kwenda, G. (2017) · PubMed Central · doi:10.11604/pamj.2017.26.108.10982 · Cited by 20 · see citing works
Complex Clonal Diversity ofStaphylococcus aureusNasal Colonization among Community Personnel, Healthcare Workers, and Clinical Students in the Eastern Province, Saudi Arabia
El-Mahdy, T. S., Al-Agamy, M. H., Emara, M. M., Barakat, A., & Goering, R. V. (2018) · BioMed Research International · doi:10.1155/2018/4208762 · Cited by 20 · see citing works
Virulence potential of Staphylococcus aureus isolates from Buruli ulcer patients
Amissah, N. A., Chlebowicz, M. A., Ablordey, A. S., Tetteh, C. S., Prah, I., van der Werf, T. S., Friedrich, A. W., van Dijl, J. M., Stienstra, Y., & Rossen, J. W. A. (2017) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2017.04.002 · Cited by 20 · see citing works
Antimicrobial resistance and genomic analysis of staphylococci isolated from livestock and farm attendants in Northern Ghana
Egyir, B., Dsani, E., Owusu-Nyantakyi, C., Amuasi, G. R., Owusu, F. A., Allegye‐Cudjoe, E., & Addo, K. K. (2022) · BMC Microbiology · doi:10.1186/s12866-022-02589-9 · Cited by 19 · see citing works
Self-citation
Characterisation of Methicillin-Resistant Staphylococcus aureus from Alexandria, Egypt
Monecke, S., Bedewy, A. K., Müller, E., Braun, S. D., Diezel, C., Elsheredy, A. G., Kader, O., Reinicke, M., Ghazal, A. A. E. R., Rezk, S., et al. (2023) · Antibiotics · doi:10.3390/antibiotics12010078 · Cited by 19 · see citing works
Characterization of Staphylococcus aureus from Human Immunodeficiency Virus (HIV) patients in Accra, Ghana
Egyir, B., Oteng, A. A., Owusu, E., Newman, M. J., Addo, K. K., & Larsen, A. R. (2016) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.7428 · Cited by 19 · see citing works
Self-citation
Methicillin Resistant Staphylococcus aureus Transmission in a Ghanaian Burn Unit: The Importance of Active Surveillance in Resource-Limited Settings
Amissah, N. A., Buultjens, A. H., Ablordey, A. S., van Dam, L., Ampomah, O.-W., Baines, S. L., Bulach, D., Tetteh, C. S., Prah, I., van der Werf, T. S., et al. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01906 · Cited by 19 · see citing works
Molecular Characterization of Staphylococcus aureus Isolated from Chronic Infected Wounds in Rural Ghana
Wolters, M., Frickmann, H., Christner, M., Both, A., Rohde, H., Oppong, K., Akenten, C. W., May, J., & Dekker, D. M. (2020) · Microorganisms · doi:10.3390/microorganisms8122052 · Cited by 19 · see citing works
Screening agars for MRSA: evaluation of a stepwise diagnostic approach with two different selective agars for the screening for methicillin-resistant Staphylococcus aureus (MRSA)
Micheel, V., Hogan, B., Köller, T., Warnke, P., Crusius, S., Hinz, R., Hagen, R. M., Schwarz, N. G., & Frickmann, H. (2015) · Military Medical Research · doi:10.1186/s40779-015-0046-1 · Cited by 18 · see citing works
An assessment on DNA microarray and sequence-based methods for the characterization of methicillin-susceptible Staphylococcus aureus from Nigeria
Shittu, A. O., Oyedara, O. O., Okon, K. O., Raji, M. A., Peters, G., von Müller, L., Schaumburg, F., Herrmann, M., & Ruffing, U. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01160 · Cited by 18 · see citing works
Antimicrobial resistance and clonality of Staphylococcus aureus causing bacteraemia in children admitted to the Manhiça District Hospital, Mozambique, over two decades
Garrine, M., Costa, S. S., Messa, A., Massora, S., Vubil, D. C., Acácio, S., Nhampossa, T., Bassat, Q., Mandomando, I., & Couto, I. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1208131 · Cited by 17 · see citing works
Methicillin-Resistant Staphylococcus aureus in Ghana: Past, Present, and Future
Donkor, E. S., Dayie, N. T. K. D., & Tette, E. M. A. (2019) · Microbial Drug Resistance · doi:10.1089/mdr.2018.0115 · Cited by 17 · see citing works
Whole Genome Sequencing and Antimicrobial Resistance of Staphylococcus aureus from Surgical Site Infections in Ghana
Egyir, B., Bentum, J., Attram, N., Fox, A., Obeng‐Nkrumah, N., Labi, A.-K., Behene, E., Kumordjie, S., Yeboah, C., Agbodzi, B., et al. (2021) · Pathogens · doi:10.3390/pathogens10020196 · Cited by 16 · see citing works
Self-citation
Whole genome sequencing revealed high proportions of ST152 MRSA among clinical Staphylococcus aureus isolates from ten hospitals in Ghana
Egyir, B., Owusu-Nyantakyi, C., Bortey, A., Amuasi, G. R., Owusu, F. A., Boateng, W., Ahmed, H., Danso, J. K., Oclu, A., Mohktar, Q., et al. (2024) · mSphere · doi:10.1128/msphere.00446-24 · Cited by 15 · see citing works
Self-citation
Acute respiratory infection and bacteraemia as causes of non-malarial febrile illness in African children: a narrative review
Muroa, F., Reyburn, R., & Reyburn, H. (2015) · Pneumonia · doi:10.15172/pneu.2015.6/488 · Cited by 15 · see citing works
Genetic Characterization of Staphylococcus aureus From Subclinical Mastitis Cases in Dairy Cows in Rwanda
Ndahetuye, J. B., Leijon, M., Båge, R., Artursson, K., & Persson, Y. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.751229 · Cited by 15 · see citing works
Study of susceptibility to antibiotics and molecular characterization of high virulence Staphylococcus aureus strains isolated from a rural hospital in Ethiopia
Verdú-Expósito, C., Romanyk, J., Cuadros-González, J., TesfaMariam, A., Copa-Patiño, J. L., Pérez-Serrano, J., & Soliveri, J. (2020) · PLOS ONE · doi:10.1371/journal.pone.0230031 · Cited by 15 · see citing works
Prevalence and genetic lineages of Staphylococcus aureus nasal colonization and urinary tract infection among people living with HIV/AIDS in Nigeria: A systematic review
Abdullahi, I. N., Issaoui, R., & Usman, Y. (2022) · IJID Regions · doi:10.1016/j.ijregi.2022.05.009 · Cited by 14 · see citing works
Molecular epidemiology of Staphylococcus aureus in post-earthquake northern Haiti
Rosenthal, M. E., Mediavilla, J. R., Chen, L., Sonnenfeld, J. J., Pierce, L., Shannon, A. H., Boucher, H. W., Pearlmutter, M. D., Kreiswirth, B. N., Kuo, Y., et al. (2014) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2014.08.007 · Cited by 14 · see citing works
Local Epidemiology of Nosocomial Staphylococcus aureus Infection in a Nigerian University Teaching Hospital
Adeyanju, A., Schaumburg, F., Onayade, A. A., Akinyoola, A. L., Adeyemi, T., Ugbo, O., Köck, R., Amusa, Y. B., Lawal, O. O., Adeyanju, T., et al. (2022) · Antibiotics · doi:10.3390/antibiotics11101372 · Cited by 11 · see citing works
Management of superficial and deep-seated Staphylococcus aureus skin and soft tissue infections in sub-Saharan Africa: a post hoc analysis of the StaphNet cohort
Alabi, A. S., Kazimoto, T., Lebughe, M., Vubil, D. C., Phaku, P., Mandomando, I., Kern, W. V., Abdulla, S., Mellmann, A., Peitzmann, L., et al. (2018) · Infection · doi:10.1007/s15010-018-1140-6 · Cited by 11 · see citing works
A six-member SNP assay on the iPlex MassARRAY platform provides a rapid and affordable alternative for typing major African Staphylococcus aureus types
Nyasinga, J., Kyanya, C. K., Okoth, R. O., Oundo, V., Matano, D., Wacira, S., Sang, W., Musembi, S., & Musila, L. A. (2019) · Access Microbiology · doi:10.1099/acmi.0.000018 · Cited by 11 · see citing works
Characteristics of Staphylococcus aureus Isolated from Patients in Busia County Referral Hospital, Kenya
Obanda, B. A., Cook, E. A. J., Fèvre, E. M., Bebora, L. C., Ogara, W. O., Wang, S., Gebreyes, W. A., Ngetich, R., Wandede, D., Muyodi, J., et al. (2022) · Pathogens · doi:10.3390/pathogens11121504 · Cited by 11 · see citing works
Staphylococcus aureus and Coagulase-Negative Staphylococci in Bacteraemia: The Epidemiology, Predisposing Factors, Pathogenicity and Antimicrobial Resistance
Grace, J.-U. A., Olayinka, B. O., Onaolapo, J. A., & Obaro, S. (2019) · Clinical Microbiology Open Access · doi:10.4172/2327-5073.1000325 · Cited by 11 · see citing works
Displacement of Hospital-Acquired, Methicillin-Resistant Staphylococcus aureus Clones by Heterogeneous Community Strains in Kenya over a 13-Year Period
Nyasinga, J., Munshi, Z., Kigen, C. K., Nyerere, A. K., Musila, L. A., Whitelaw, A. C., Ziebuhr, W., & Revathi, G. (2024) · Microorganisms · doi:10.3390/microorganisms12061171 · Cited by 9 · see citing works
Methicillin-resistant Staphylococcus aureus prevalence in food-producing animals and food products in Saudi Arabia: A review
Alkuraythi, D. M., & Alkhulaifi, M. M. (2024) · Veterinary World · doi:10.14202/vetworld.2024.1753-1764 · Cited by 9 · see citing works
Secondary Infection of Buruli Ulcer Lesions
Kpeli, G. S., & Yeboah‐Manu, D. (2019) · Springer eBooks · doi:10.1007/978-3-030-11114-4_13 · Cited by 9 · see citing works
Molecular Characterization of Methicillin-ResistantStaphylococcus aureusIsolates, Isolated from a Burn Hospital in Southwest Iran in 2006 and 2014
Ghaznavi‐Rad, E., & Ekrami, A. (2018) · International Journal of Microbiology · doi:10.1155/2018/1423939 · Cited by 9 · see citing works
Molecular investigations on a chimeric strain of Staphylococcus aureus sequence type 80
Gawlik, D., Ruppelt-Lorz, A., Müller, E., Reißig, A., Hotzel, H., Braun, S. D., Söderquist, B., Ziegler-Cordts, A., Stein, C., Pletz, M. W., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0232071 · Cited by 9 · see citing works
Clonal Complexes Distribution of Staphylococcus aureus Isolates from Clinical Samples from the Caribbean Islands
Monecke, S., Akpaka, P. E., Smith, M. R., Unakal, C. G., Thoms-Rodriguez, C.-A., Ashraph, K., Müller, E., Braun, S. D., Diezel, C., Reinicke, M., et al. (2023) · Antibiotics · doi:10.3390/antibiotics12061050 · Cited by 8 · see citing works
Survey ofStaphylococcus aureuscarriage by free‐living red deer (Cervus elaphus): Evidence of human and domestic animal lineages
Luzzago, C., Lauzi, S., Ehricht, R., Monecke, S., Corlatti, L., Pedrotti, L., & Piccinini, R. (2022) · Transboundary and Emerging Diseases · doi:10.1111/tbed.14500 · Cited by 8 · see citing works
Molecular characterization of methicillin-resistant Staphylococcus aureus isolates from a hospital in Ghana
Asante, J., Govinden, U., Owusu-Ofori, A. K., Bester, L. A., & Essack, S. Y. (2019) · African Journal of Clinical and Experimental Microbiology · doi:10.4314/ajcem.v20i3.1 · Cited by 8 · see citing works
Molecular Epidemiology, Antimicrobial Resistance, and Virulence Profiles of Staphylococcus aureus from Fish, Aquatic Environments, and Fish Handlers in Southeast Nigeria
Okafor, U. C., Okorie-Kanu, O. J., Ogugua, A. J., Ikeogu, C. F., Okafor, S. C., Anyanwu, M. U., Nwobi, O. C., Anyaoha, C. O., Mgbeahuruike, A. C., Majesty-Alukagberie, L. O., et al. (2025) · Microorganisms · doi:10.3390/microorganisms13092059 · Cited by 7 · see citing works
Predominance of t355/ST152/SCCmec V clonal type among PVL-positive MRSA isolates in a tertiary care hospital in Belgrade, Serbia
Rakonjac, B., Lepšanović, Z., Šuljagić, V., Jovčić, B., Kojić, M., Larsen, A. R., Đurić, M., & Cirkovic, I. B. (2022) · PLoS ONE · doi:10.1371/journal.pone.0273474 · Cited by 7 · see citing works
Self-citation
Distribution of genes encoding aminoglycoside modifying enzymes amongst methicillin resistant and methicillin sensitive Staphylococcus aureus isolates from Nigerian hospitals
Alli, O. A. T., David, O., Kunle, P. B., Aderayo, A. A., & Adeolu, O. (2015) · African Journal of Microbiology Research · doi:10.5897/ajmr2014.7300 · Cited by 6 · see citing works
Antibiotic profile of Staphylococcus aureus and Coagulase negative Staphylococci species isolated from raw camel milk from Garissa County, Kenya
Kirwa, E., Aboge, G. O., Maitho, T., Mbindyo, C. M., Okumu, T. A., & Mainga, A. O. (2021) · East African Journal of Science Technology and Innovation · doi:10.37425/eajsti.v2i4.364 · Cited by 6 · see citing works
Invitro inhibitory effect of Lactic acid bacteria isolated from Kunun zaki against multi-drug resistant diarrhogenic bacteria in HIV patients in Jos, Nigeria
Ngene, A. C., Musa, S., Egbere, O. J., Odu, C. E., Danladi, M. M. A., Onyimba, I. A., Dashen, M. M., Ochiheche, E., Nguhemen, H., & Ogaji, A. O. (2023) · Microbes and Infectious Diseases /Microbes and Infectious Diseases · doi:10.21608/mid.2023.175533.1418 · Cited by 6 · see citing works
Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound-treatment centres in Ghana
Yeboah‐Manu, D. (2016) · doi:10.26226/morressier.56d5ba30d462b80296c954a8 · Cited by 5 · see citing works
Prevalence and associated risk factors of Staphylococcus aureus nasal colonization among a cohort of immunocompromised individuals in Lagos, Nigeria
Ogunleye, B. O., Oshamika, O. O., Akinpelu, S. O., Ajayi, A. S., Akinduti, P. A., Oyedeji, K. S., Odeniyi, O. M., & Akinnola, O. O. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-12416-x · Cited by 3 · see citing works
Spa gene-based molecular typing of nasal methicillin-susceptible staphylococcus aureus from patients and health-care workers in a dialysis center in southeast Iran
Saffari, F., Radfar, A., Sobhanipoor, M. H., & Ahmadrajabi, R. (2020) · Pathogens and Global Health · doi:10.1080/20477724.2020.1743933 · Cited by 3 · see citing works
Multidrug resistance including borderline-oxacillin resistance and spa typing of Staphylococcus aureus from milk and milk products of Tigray region, Northern Ethiopia
Tarekgne, E. K., Skjerdal, T., Skeie, S. B., Rudi, K., Porcellato, D., & Narvhus, J. (2025) · BMC Veterinary Research · doi:10.1186/s12917-025-05060-9 · Cited by 2 · see citing works
Prevalence and genotypic characteristics of Panton-Valentine Leukocidin-producing Staphylococcus aureus isolates obtained in Jos, North Central Nigeria
Essien, U. C., Boswihi, S. S., Agbakoba, N. R., & Udo, E. E. (2021) · World Journal of Advanced Research and Reviews · doi:10.30574/wjarr.2021.11.2.0387 · Cited by 2 · see citing works
Rapid Detection of Panton–Valentine Leukocidin Production in Clinical Isolates of Staphylococcus aureus from Saxony and Brandenburg and Their Molecular Characterisation
Müller, E., Monecke, S., Porta, M. A., Encalada, M. V. N., Reißig, A., Rüttiger, L., Schröttner, P., Schwede, I., Söffing, H.-H., Thürmer, A., et al. (2025) · Pathogens · doi:10.3390/pathogens14030238 · Cited by 2 · see citing works
The combination of mupirocin and Kayvirus broadens the decolonization effect against Staphylococcus aureus
Siváková, A., Figallová, E., Botka, T., Vacek, L., Tkadlec, J., Vrbský, J., Osowski, M., Petřáš, P., Kleknerová, D. P., Dvořáčková, M., et al. (2026) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-026-13814-0 · Cited by 1 · see citing works
Anti-microbial Activities of Selected Ghanaian Medicinal Plants and Four Structurally Similar Anti-protozoan Compounds against Susceptible and Multi-drug Resistant Bacteria
Antwi, A., Owusu, K. K., Amoa‐Bosompem, M., Williams, N., Ayertey, F., Akyeh, M. L., Agyapong, J., Tetteh, T., Djameh, G. I., Botchie, S. K., et al. (2017) · European Journal of Medicinal Plants · doi:10.9734/ejmp/2017/35437 · Cited by 1 · see citing works
Self-citation
Antibiotics resistance patterns of Panton-Valentine leukocidin-positive methicillin-resistant staphylococci isolated from clinical samples in Abidjan, Cte dIvoire
Kouamé-Sina, S. M., N’golo, D. C., Fernique, K., Yakoura, K. O., Kan, S. K., Solange, N., Nathalie, K. G., & Adjehi, D. (2018) · African Journal of Microbiology Research · doi:10.5897/ajmr2018.8986 · Cited by 1 · see citing works
Nasal Colonization with Methicillin-Resistant Staphylococcus Aureus (Mrsa) among Hiv-Infected Children.
Kotey, F. C. N. (2018) · Cited by 1 · see citing works
Rapid Detection of Panton-Valentine Leukocidin (PVL) Gene from Staphylococcus aureus Clinical Isolates
Girgis, S. A., & Ahmed, O. M. (2017) · International Journal of Current Microbiology and Applied Sciences · doi:10.20546/ijcmas.2017.601.036
Epidemiology of Staphylococcus aureus in a burn unit of a tertiary care center in Bhubaneswar
Das, D. J. K. (2018) · Journal of Medical Science And clinical Research · doi:10.18535/jmscr/v6i12.187
Carriage and Antibiogram of Methicillin Resistant Staphylococcus Aureus among Admitted Patients of a Surgical Ward in A Tertiary Hospital, South Western UgandaPreprint
Musinguzi, B., Mugimba, P., Baguma, A., Itabangi, H., & Bazira, J. (2021) · Research Square · doi:10.21203/rs.3.rs-529905/v1
Prevalence and Antibiotic Resistance Mechanisms of Methicillin-Resistant Staphylococcus aureus isolates from Selected Hospitals in Ashanti Region, Ghana.Preprint
Zumbi, C. N., Boamah, V. E., Boakye, Y. D., Odoi, H., & Agyare, C. (2021) · Research Square · doi:10.21203/rs.3.rs-602638/v1
Peer Review #1 of "Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana (v0.1)"
(2017) · PeerJ · doi:10.7287/peerj.3047v0.1/reviews/1
Peer Review #2 of "Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana (v0.2)"
(2017) · PeerJ · doi:10.7287/peerj.3047v0.2/reviews/2
Peer Review #2 of "Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana (v0.1)"
(2017) · PeerJ · doi:10.7287/peerj.3047v0.1/reviews/2

Antibiotic resistance and clonal diversity of invasive Staphylococcus aureus in the rural Ashanti Region, Ghana
Dekker, D., Wolters, M., Mertens, E., Boahen, K. G., Krumkamp, R., Eibach, D., Schwarz, N. G., Adu-Sarkodie, Y., Rohde, H., Christner, M., et al. (2016) · BMC Infectious Diseases · doi:10.1186/s12879-016-2048-3 · Cited by 40 · see citing works
Whole Genome Sequencing and Antimicrobial Resistance of Staphylococcus aureus from Surgical Site Infections in Ghana
Egyir, B., Bentum, J., Attram, N., Fox, A., Obeng‐Nkrumah, N., Labi, A.-K., Behene, E., Kumordjie, S., Yeboah, C., Agbodzi, B., et al. (2021) · Pathogens · doi:10.3390/pathogens10020196 · Cited by 16 · see citing works
Self-citation
Methicillin-resistant Staphylococcus aureus strains from Ghana include USA300
Egyir, B., Guardabassi, L., Monecke, S., Addo, K. K., Newman, M. J., & Larsen, A. R. (2014) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2014.11.006 · Cited by 31 · see citing works
Self-citation
Whole genome sequencing revealed high proportions of ST152 MRSA among clinical Staphylococcus aureus isolates from ten hospitals in Ghana
Egyir, B., Owusu-Nyantakyi, C., Bortey, A., Amuasi, G. R., Owusu, F. A., Boateng, W., Ahmed, H., Danso, J. K., Oclu, A., Mohktar, Q., et al. (2024) · mSphere · doi:10.1128/msphere.00446-24 · Cited by 15 · see citing works
Self-citation
Antibiotic susceptibility patterns and blaPER-1 β-lactamase-producing Acinetobacter baumannii isolated from hospitalised patients
Sharif, F., Moniri, R., Bagheri-Josheghani, S., & Dastehgoli, K. (2014) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2014.11.002 · Cited by 1 · see citing works

Authors: Egyir, B., Guardabassi, L., Sørum, M., Nielsen, S. S., Kolekang, A., Frimpong, E., Addo, K. K., Newman, M. J., & Larsen, A. R.
Affiliations: Statens Serum Institut (DK)
University of Copenhagen (DK)
Kwame Nkrumah University of Science and Technology (GH)
Noguchi Memorial Institute for Medical Research (GH)
University of Ghana (GH)
Corresponding author: Egyir, Beverly
ORCID: Egyir, Beverly
Guardabassi, Luca
Nielsen, Søren Saxmose
Addo, Kennedy Kwasi
Larsen, Anders Rhod
Venue: PLoS ONE
Publisher: Public Library of Science (PLoS)
Published: 2014-02-25
Volume: 9
Issue: 2
Pages: e89716
ISSN: 1932-6203 (ISSN-L)
DOI: 10.1371/journal.pone.0089716
PMC: PMC3934920
OpenAlex: W2071056263
Cited by: 108
References: 38
Citations by year: 2026: 5 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 9 · 2021: 8 · 2020: 10 · 2019: 10 · 2018: 11 · 2017: 16 · 2016: 9 · 2015: 11 · 2014: 6
FWCI: 9.84
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (unspecified)
Locations: PLoS ONE (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, other-oa)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Research at the University of Copenhagen (University of Copenhagen) (submittedVersion, cc-by)
Greater South Information System
Funders: Danish International Development Agency
Topics: Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
Keywords: Staphylococcus aureus, antimicrobial resistance, methicillin-resistant Staphylococcus aureus, spa typing, clonal complexes, Panton-Valentine leukocidin, SCCmec typing, multilocus sequence typing, mecA gene, penicillin resistance, tetracycline resistance, erythromycin resistance, nosocomial infections, Ghana
MeSH terms: Ghana, Humans, Microbial Sensitivity Tests, Prospective Studies, Staphylococcal Skin Infections, Staphylococcus aureus, Molecular Epidemiology, Methicillin-Resistant Staphylococcus aureus

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Molecular Epidemiology and Antimicrobial Susceptibility of Clinical Staphylococcus aureus from Healthcare Institutions in Ghana

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