The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
Internet-Delivered Cognitive Behavior Therapy for Adolescents with Obsessive-Compulsive Disorder: An Open Trial
Open accessAbstract
BACKGROUND: International guidelines recommend Cognitive Behavior Therapy (CBT) as the first line treatment for pediatric obsessive-compulsive disorder (OCD). However, a substantial proportion of patients do not have access to such treatment. We developed and tested the feasibility, efficacy and acceptability of a novel therapist-guided, Internet-delivered CBT (ICBT) platform for adolescents with OCD. METHODS: An interactive, age-appropriate ICBT platform ("BiP OCD") was developed. Twenty-one adolescents (12-17 years) with a DSM-IV diagnosis of OCD and their parents were enrolled in the study. All participants received 12 weeks of ICBT with therapist support. The primary outcome measure was the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS). Acceptability was assessed at post-treatment. RESULTS: Participants completed on average 8.29 (SD = 3.0) of the 12 treatment chapters. Treatment yielded significant improvements on all clinician-, parent- and most self-administered outcome measures, with a large effect size of d = 2.29 (95% CI 1.5-3.07) on the CY-BOCS. Patients continued to improve at follow-up. At 6-month follow-up, 71% were classified as responders (≥35% decrease on the CY-BOCS) and 76% as being in remission (CY-BOCS score ≤12). Average clinician support time was less than 20 minutes per patient per week. The majority of participants felt that BiP OCD was age-appropriate and rated the treatment as good or very good. CONCLUSIONS: ICBT could be efficacious, acceptable, and cost-effective for adolescents with OCD. More rigorously controlled studies are needed to further evaluate the treatment. TRIAL REGISTRATION: ClinicalTrials.gov; NCT01809990.
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“Adolescents and their parents generally expressed satisfaction with the intervention and the majority would recommend it to others, corresponding to what previous studies of similar interventions have found (Spence et al., 2011; Lenhard et al., 2014; Wuthrich et al., 2012).”
From Internet-based cognitive behavioral therapy for adolescents with anxiety disorders: A feasibility study (2018) · cites this paper as Lenhard et al., 2014
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BackgroundChildren's Yale-Brown Obsessive Compulsive Scale: Reliability and Validity
SCAHILL, L., RIDDLE, M. A., McSWIGGIN-HARDIN, M., ORT, S. I., KING, R. A., GOODMAN, W. K., CICCHETTI, D., & LECKMAN, J. F. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199706000-00023 · Cited by 2,045
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Vigerland, S., Lenhard, F., Bonnert, M., Lalouni, M., Hedman, E., Ahlen, J., Olén, O., Serlachius, E., & Ljótsson, B. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2016.09.005 · Cited by 292
“Four of the included studies were written by coauthors of this review (Bonnert et al., 2014; Lenhard et al., 2014; Vigerland et al., 2013; Vigerland et al., 2016).”
BackgroundSelf-citationRemote cognitive-behavior therapy for obsessive-compulsive symptoms: A meta-analysis.
Wootton, B. M. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2015.10.001 · Cited by 162
Obsessive-compulsive disorder in children and adolescents
Krebs, G., & Heyman, I. (2009) · Archives of Disease in Childhood · doi:10.1136/archdischild-2014-306934 · Cited by 304
Lenhard, F., Andersson, E., Mataix-Cols, D., Rück, C., Vigerland, S., Högström, J., Hillborg, M., Brander, G., Ljungström, M., Ljótsson, B., et al. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2016.09.515 · Cited by 146
Neuroscience-informed psychoeducation for addiction medicine: A neurocognitive perspective
Ekhtiari, H., Rezapour, T., Aupperle, R. L., & Paulus, M. P. (2017) · Progress in brain research · doi:10.1016/bs.pbr.2017.08.013 · Cited by 134
Metadata
- Authors
- Lenhard, F., Vigerland, S., Andersson, E., Rück, C., Mataix-Cols, D., Thulin, U., Ljótsson, B., & Serlachius, E.
- Affiliations
- Karolinska Institutet (SE)
- Corresponding author
- Lenhard, Fabian
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-06-20
- Volume
- 9
- Issue
- 6
- Pages
- e100773
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4065049
- OpenAlex
- W2116170399
- Cited by
- 104
- References
- 66
- Citations by year
- 2025: 1 · 2024: 9 · 2023: 3 · 2022: 8 · 2021: 21 · 2020: 5 · 2019: 10 · 2018: 7 · 2017: 16 · 2016: 12 · 2015: 10 · 2014: 2
- FWCI
- 20.73
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Funders
- Karolinska Institutet
- Stockholms Läns Landsting (20120167)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- internet-based cognitive behavioral therapy, obsessive-compulsive disorder, adolescents, pediatric OCD, treatment acceptability, treatment efficacy, treatment feasibility, Children's Yale-Brown Obsessive Compulsive Scale, parental involvement
- MeSH terms
- Adolescent, Child, Female, Humans, Male, Obsessive-Compulsive Disorder, Parents, Severity of Illness Index, Cognitive Behavioral Therapy, Treatment Outcome, Telemedicine, Internet
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