Cited by 146Digital Mental Health InterventionsObsessive-Compulsive Spectrum DisordersAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Therapist-guided, internet-delivered cognitive-behavioral therapy for adolescents with obsessive-compulsive disorder: a randomized controlled trial

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Lenhard, Fabian, Andersson, Erik, Mataix-Cols, David, Rück, Christian, Vigerland, Sarah, Högström, Jens, Hillborg, Maria, Brander, Gustaf +3 more·2017·Journal of the American Academy of Child & Adolescent Psychiatry

Abstract

OBJECTIVE: Cognitive-behavioral therapy (CBT) is the first-line treatment for young people with obsessive-compulsive disorder (OCD), but most patients do not have access to this treatment. Thus, innovative ways to increase the accessibility of CBT are needed. The objective of this trial was to evaluate the efficacy of therapist-guided internet-based CBT (ICBT) for adolescents with OCD. METHOD: Sixty-seven adolescents (12-17 years old) with OCD were randomly assigned to a 12-week clinician- and parent-supported ICBT program (BiP OCD) or a waitlist condition. The primary outcome was the Children Yale-Brown Obsessive Compulsive Scale (CY-BOCS) administered by blinded assessors before and after the intervention. All patients were followed up 3 months after the intervention. RESULTS: In intention-to-treat analyses, BiP OCD was superior to waitlist on the CY-BOCS (time-by-group interaction, B = -4.53, z = -3.74, p < .001; Cohen's d = 0.69; 95% CI 0.19-1.18) and on most secondary outcome measurements. Patients randomized to BiP OCD also showed further improvement from post-treatment to 3-month follow-up, with a within-group pretreatment to follow-up effect size (Cohen's d) equal to 1.68 (95% CI 1.00-2.36). Patient satisfaction with BiP OCD was high. There were no relevant adverse events. Average clinician support time was 17.5 minutes per patient per week. CONCLUSION: Therapist-guided ICBT is a promising low-intensity intervention for adolescents with OCD and has the potential to increase access to CBT. It might be particularly useful in a stepped-care approach, in which a large proportion of patients with moderately severe OCD could first be offered ICBT, thus freeing limited resources for more complex cases. Clinical trial registration information-Internet-Delivered CBT for Adolescents With OCD: A Randomized Controlled Study (BiPOCD); http://clinicaltrials.gov; NCT02191631.

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  • In a single-blinded randomized controlled trial with sixty-seven adolescents (aged 12-17) suffering from obsessive-compulsive disorder (OCD), a 12-week clinician and parent supported ICBT-intervention proved superior to wait-list controls on the Children's Yale-Brown Obsessive-Compulsive Scale with an effect-size of d = 0.69 (p < 0.001).

    “Most recently, Lenhard et al. (2017) reported results from a single-blinded randomized controlled trial with sixty-seven adolescents (aged 12–17) suffering from obsessive-compulsive disorder (OCD). In this trial, a 12-week clinician and parent supported ICBT-intervention proved superior to wait-list controls on the semi-structured clinician-administered interview Children's Yale-Brown Obsessive-”

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Research works printed but not linked: 1

  1. NICE. Obsessive-compulsive disorder: core interventions in the treat- ment of obsessive-compulsive disorder and body dysmorphic disorder. http://www.ncbi.nlm.nih.gov/books/NBK56458/. Published 2006. Accessed December 18, 2012.

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Authors
Lenhard, F., Andersson, E., Mataix-Cols, D., Rück, C., Vigerland, S., Högström, J., Hillborg, M., Brander, G., Ljungström, M., Ljótsson, B., & Serlachius, E.
Affiliations
  • Region Stockholm (SE)
  • Karolinska Institutet (SE)
Corresponding author
Lenhard, Fabian
Venue
Journal of the American Academy of Child & Adolescent Psychiatry
Publisher
Elsevier BV
Published
2017-01
Volume
56
Issue
1
Pages
10-19.e2
ISSN
0890-8567 (ISSN-L)
OpenAlex
W2538766504
Cited by
146
References
43
Citations by year
2026: 8 · 2025: 11 · 2024: 15 · 2023: 11 · 2022: 19 · 2021: 27 · 2020: 11 · 2019: 19 · 2018: 14 · 2017: 9 · 2016: 2
FWCI
22.53
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
  • Karolinska Institutet
  • Stockholms Läns Landsting (20120167, 20140085)
  • Vetenskapsrådet (K2013‐61P‐22168, 2014-04052)
  • Forskningsrådet om Hälsa, Arbetsliv och Välfärd (2014-4052)
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
obsessive-compulsive disorder, adolescents, internet-based cognitive behavioral therapy, therapist-guided intervention, treatment accessibility, stepped care, low-intensity intervention, parental support, treatment efficacy, patient satisfaction
MeSH terms
Adolescent, Child, Female, Follow-Up Studies, Humans, Male, Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Single-Blind Method, Outcome Assessment, Health Care, Internet

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