The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
Internet-Delivered Cognitive Behavior Therapy for Adolescents with Obsessive-Compulsive Disorder: An Open Trial
Open accessAbstract
BACKGROUND: International guidelines recommend Cognitive Behavior Therapy (CBT) as the first line treatment for pediatric obsessive-compulsive disorder (OCD). However, a substantial proportion of patients do not have access to such treatment. We developed and tested the feasibility, efficacy and acceptability of a novel therapist-guided, Internet-delivered CBT (ICBT) platform for adolescents with OCD. METHODS: An interactive, age-appropriate ICBT platform ("BiP OCD") was developed. Twenty-one adolescents (12-17 years) with a DSM-IV diagnosis of OCD and their parents were enrolled in the study. All participants received 12 weeks of ICBT with therapist support. The primary outcome measure was the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS). Acceptability was assessed at post-treatment. RESULTS: Participants completed on average 8.29 (SD = 3.0) of the 12 treatment chapters. Treatment yielded significant improvements on all clinician-, parent- and most self-administered outcome measures, with a large effect size of d = 2.29 (95% CI 1.5-3.07) on the CY-BOCS. Patients continued to improve at follow-up. At 6-month follow-up, 71% were classified as responders (≥35% decrease on the CY-BOCS) and 76% as being in remission (CY-BOCS score ≤12). Average clinician support time was less than 20 minutes per patient per week. The majority of participants felt that BiP OCD was age-appropriate and rated the treatment as good or very good. CONCLUSIONS: ICBT could be efficacious, acceptable, and cost-effective for adolescents with OCD. More rigorously controlled studies are needed to further evaluate the treatment. TRIAL REGISTRATION: ClinicalTrials.gov; NCT01809990.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures



Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Adolescents and their parents generally expressed satisfaction with the intervention and the majority would recommend it to others, corresponding to what previous studies of similar interventions have found (Spence et al., 2011; Lenhard et al., 2014; Wuthrich et al., 2012).”
From Internet-based cognitive behavioral therapy for adolescents with anxiety disorders: A feasibility study (2018) · cites this paper as Lenhard et al., 2014
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Intraclass correlations: Uses in assessing rater reliability.
Shrout, P. E., & Fleiss, J. L. (1979) · Psychological Bulletin · doi:10.1037/0033-2909.86.2.420 · Cited by 24,532
Multiple Imputation for Nonresponse in Surveys
Rubin, D. B. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316696 · Cited by 20,701
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139
The Strengths and Difficulties Questionnaire: A research note
Goodman, R. (1997) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1997.tb01545.x · Cited by 14,908
(1998) · PubMed · Cited by 10,216
(1976) · Medical Entomology and Zoology · Cited by 8,899
The mini international neuropsychiatric interview
Lecrubier, Y., Sheehan, D. V., Hergueta, T., & Weiller, E. (1998) · European Psychiatry · doi:10.1016/s0924-9338(99)80239-9 · Cited by 5,899
A Children's Global Assessment Scale (CGAS)
Shaffer, D. (1983) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790100074010 · Cited by 3,716 · cited 1×
“Children’s Global Assessment Scale (CGAS [36]) is an instrument to quantify the overall level of functioning in children and adolescents.”
BackgroundChildren's Yale-Brown Obsessive Compulsive Scale: Reliability and Validity
SCAHILL, L., RIDDLE, M. A., McSWIGGIN-HARDIN, M., ORT, S. I., KING, R. A., GOODMAN, W. K., CICCHETTI, D., & LECKMAN, J. F. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199706000-00023 · Cited by 2,045
A measure of anxiety symptoms among children
Spence, S. H. (1998) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(98)00034-5 · Cited by 1,928
Treatment gap in mental health care.
Abramowitz, M. Z., Greenberg, D., & Levav, I. (2008) · PubMed · Cited by 1,483
The treatment gap in mental health care.
(2004) · Europe PMC (PubMed Central) · Cited by 1,419
Smartphones for smarter delivery of mental health programs: A systematic review
Donker, T., Petrie, K., Proudfoot, J., Clarke, J., Birch, M.-R., & Christensen, H. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2791 · Cited by 1,136 · cited 1×
“A small number of studies have evaluated smartphone as the solitary format of treatment delivery [59], underlining the potential of smartphone applications as an extension of ICBT.”
BackgroundPractice Guideline for the Treatment of Patients With Obsessive-Compulsive Disorder
(2008) · APA Practice Guidelines for the Treatment of Psychiatric Disorders: Comprehensive Guidelines and Guideline Watches · doi:10.1176/appi.books.9780890423363.149114 · Cited by 1,028
Abramowitz, J. S., Taylor, S., & McKay, D. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60240-3 · Cited by 1,002
National Collaborating Centre for Mental Health
Veale, D. M. (2006) · Research Portal (King's College London) · Cited by 941
Obsessive Compulsive Disorder in Adolescence: An Epidemiological Study
FLAMENT, M. F., WHITAKER, A., RAPOPORT, J. L., DAVIES, M., BERG, C. Z., KALIKOW, K., SCEERY, W., & SHAFFER, D. (1988) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-198811000-00018 · Cited by 684
Hedman, E., Ljótsson, B., & Lindefors, N. (2012) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1586/erp.12.67 · Cited by 672
Self-citationA 40-Year Follow-up of Patients With Obsessive-compulsive Disorder
Skoog, G., & Skoog, I. G. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.2.121 · Cited by 634
Functional Impairment in Children and Adolescents with Obsessive-Compulsive Disorder
Piacentini, J. C., Bergman, R. L., Keller, M. L., & McCracken, J. T. (2003) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/104454603322126359 · Cited by 589
Internet-based self-help for depression: randomised controlled trial
Andersson, G., Bergström, J., Holländare, F., Carlbring, P., Kaldo, V., & Ekselius, L. (2005) · British Journal of Psychiatry · doi:10.1192/bjp.187.5.456 · Cited by 529 · cited 1×
“Furthermore, non-inferiority trials indicate that ICBT is at least as effective as traditional face-to-face CBT for depression, social anxiety disorder and panic disorder [20–22].”
BackgroundEffects of psychotherapy for anxiety in children and adolescents: A meta-analytic review
Reynolds, S., Wilson, C., Austin, J., & Hooper, L. (2012) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.01.005 · Cited by 483
Frequency of obsessive-compulsive disorder in a community sample of young adolescents
VALLENI-BASILE, L. A., GARRISON, C. Z., JACKSON, K. L., WALLER, J. L., McKEOWN, R. E., ADDY, C. L., & CUFFE, S. P. (1994) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199407000-00002 · Cited by 468
Cognitive-Behavioral Family Treatment of Childhood Obsessive-Compulsive Disorder: A Controlled Trial
Barrett, P. M., Farrell, L. J., & March, J. S. (2004) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200401000-00014 · Cited by 430
A randomized controlled trial of online versus clinic-based CBT for adolescent anxiety.
Spence, S. H., Donovan, C. L., March, S., Gamble, A., Anderson, R. E., Prosser, S., & Kenardy, J. (2011) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0024512 · Cited by 381 · cited 1×
“To date, only a handful of case series and open trials [28,29] and two randomized controlled studies of therapist-supported ICBT for pediatric anxiety disorders [30,31] have been conducted.”
BackgroundMarch, S., Spence, S. H., & Donovan, C. L. (2009) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsn099 · Cited by 315 · cited 1×
“To date, only a handful of case series and open trials [28,29] and two randomized controlled studies of therapist-supported ICBT for pediatric anxiety disorders [30,31] have been conducted.”
BackgroundFullana, M. A., Mataix‐Cols, D., Caspi, A., Harrington, H., Grisham, J. R., Moffitt, T. E., & Poulton, R. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.08071006 · Cited by 307
Meta‐analysis of randomized, controlled treatment trials for pediatric obsessive‐compulsive disorder
Watson, H. J., & Rees, C. S. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2007.01875.x · Cited by 304
Piacentini, J. C., Bergman, R. L., Chang, S. W., Langley, A. K., Peris, T. S., Wood, J. J., & McCracken, J. T. (2011) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2011.08.003 · Cited by 287
Hedman, E., Andersson, G., Ljótsson, B., Andersson, E., Rück, C., Mörtberg, E., & Lindefors, N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018001 · Cited by 285
Self-citationAndersson, E., Enander, J., Andrén, P., Hedman, E., Ljótsson, B., Hursti, T., Bergström, J., Kaldo, V., Lindefors, N., Andersson, G., et al. (2012) · Psychological Medicine · doi:10.1017/s0033291712000244 · Cited by 274
Self-citationThe effectiveness of treatment for pediatric obsessive-compulsive disorder: A meta-analysis
Abramowitz, J. S., Whiteside, S. P. H., & Deacon, B. J. (2005) · Behavior Therapy · doi:10.1016/s0005-7894(05)80054-1 · Cited by 274
Richardson, T., Stallard, P., & Velleman, S. (2010) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-010-0069-9 · Cited by 272 · cited 1×
“To date, only a handful of case series and open trials [28,29] and two randomized controlled studies of therapist-supported ICBT for pediatric anxiety disorders [30,31] have been conducted.”
BackgroundMarch, J. S., Mulle, K., & Herbel, B. L. (1994) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199403000-00006 · Cited by 244
Storch, E. A., Caporino, N. E., Morgan, J. R., Lewin, A. B., Rojas, A., Brauer, L., Larson, M. J., & Murphy, T. K. (2011) · Psychiatry Research · doi:10.1016/j.psychres.2011.05.047 · Cited by 240 · cited 1×
“Another promising add-on to ICBT would be videoteleconferencing and web-camera approaches, as a way to deliver face-to-face CBT to patients living in remote areas [60,61].”
BackgroundPiacentini, J. C., Peris, T. S., Bergman, R. L., Chang, S. W., & Jaffer, M. (2007) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374410701662790 · Cited by 229
Hedman, E., Ljótsson, B., Rück, C., Furmark, T., Carlbring, P., Lindefors, N., & Andersson, G. (2010) · Computers in Human Behavior · doi:10.1016/j.chb.2010.01.010 · Cited by 220 · cited 1×
“All self- and parent-rated measures were administered online, a method which has been shown to be reliable and to produce results similar to traditional paper-and-pencil administration [41].”
MethodSelf-citationSimpson, H. B., Maher, M. J., Wang, Y., Bao, Y., Foa, E. B., & Franklin, M. (2011) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0022659 · Cited by 217
Treatment Response, Symptom Remission, and Wellness in Obsessive-Compulsive Disorder
Farris, S. G., McLean, C. P., Van Meter, P. E., Simpson, H. B., & Foa, E. B. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12m07789 · Cited by 216
Long-term outcomes of obsessive–compulsive disorder: follow-up of 142 children and adolescents
Micali, N., Heyman, I., Pérez, M., Hilton, K., Nakatani, E., Turner, C. M., & Mataix‐Cols, D. (2010) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.109.075317 · Cited by 216
Bergström, J., Andersson, G., Ljótsson, B., Rück, C., Andréewitch, S., Karlsson, A., Carlbring, P., Andersson, E., & Lindefors, N. (2010) · BMC Psychiatry · doi:10.1186/1471-244x-10-54 · Cited by 202
Helpseeking and access to mental health treatment for obsessive-compulsive disorder.
Goodwin, R., Koenen, K. C., Hellman, F., Guardino, M., & Struening, E. (2002) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2002.01221.x · Cited by 163
Self-help with minimal therapist contact for obsessive–compulsive disorder: a review
Mataix‐Cols, D., & Marks, I. M. (2005) · European Psychiatry · doi:10.1016/j.eurpsy.2005.07.003 · Cited by 146
Internet-Delivered, Family-Based Treatment for Early-Onset OCD: A Preliminary Case Series
Comer, J. S., Furr, J. M., Cooper-Vince, C. E., Kerns, C. E., Chan, P. T., Edson, A. L., Khanna, M., Franklin, M., Garcia, A., & Freeman, J. (2013) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2013.855127 · Cited by 129
Remote treatment of obsessive-compulsive disorder: A randomized controlled trial
Wootton, B. M., Dear, B. F., Johnston, L., Terides, M. D., & Titov, N. (2013) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2013.07.002 · Cited by 125 · cited 1×
“The efficacy of ICBT for adults with OCD has been demonstrated in two uncontrolled studies and two randomized waitlist-controlled trials, with large within-group as well as between-group effect sizes [23–26].”
BackgroundKenwright, M., Marks, I., Graham, C., Franses, A., & Mataix‐Cols, D. (2005) · Journal of Clinical Psychology · doi:10.1002/jclp.20204 · Cited by 125
Self-citationWewetzer, C., Jans, T., Müller, B., Neudörfl, A., Bücherl, U., Remschmidt, H., Warnke, A., & Herpertz‐Dahlmann, B. (2001) · European Child & Adolescent Psychiatry · doi:10.1007/s007870170045 · Cited by 120
The preliminary development of a new self‐report measure for OCD in young people
Shafran, R., Frampton, I. J., Heyman, I., Reynolds, M., Teachman, B. A., & Rachman, S. (2003) · Journal of Adolescence · doi:10.1016/s0140-1971(02)00083-0 · Cited by 113
Bolton, D., & Perrin, S. G. (2007) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2006.11.002 · Cited by 110
Examining the Psychometric Properties of the Family Accommodation Scale-Parent-Report (FAS-PR)
Flessner, C. A., Sapyta, J. J., Garcia, A. M., Freeman, J. B., Franklin, M. E., Foa, E. B., & March, J. S. (2010) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-010-9196-3 · Cited by 102
Rating scales and assessment instruments for use in pediatric psychopharmacology research.
(1985) · PubMed · Cited by 99
Obsessive-compulsive disorder; chronic versus non-chronic symptoms
Visser, H. A. D., van Oppen, P., van Megen, H. J. G. M., Eikelenboom, M., & van Balkom, A. J. L. M. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.09.004 · Cited by 95
Internet-based cognitive behavior therapy for obsessive compulsive disorder: A pilot study
Andersson, E., Ljótsson, B., Hedman, E., Kaldo, V., Paxling, B., Andersson, G., Lindefors, N., & Rück, C. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-125 · Cited by 94
Williams, T. I., Salkovskis, P. M., Forrester, L. M., Turner, S. M., White, H., & Allsopp, M. A. (2009) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-009-0077-9 · Cited by 88
Is childhood OCD a risk factor for eating disorders later in life? A longitudinal study
Micali, N., Hilton, K., Natatani, E., Heyman, I., Turner, C. M., & Mataix‐Cols, D. (2011) · Psychological Medicine · doi:10.1017/s003329171100078x · Cited by 75
An Internet administered treatment program for obsessive–compulsive disorder: A feasibility study
Wootton, B. M., Titov, N., Dear, B. F., Spence, J., Andrews, G., Johnston, L., & Solley, K. (2011) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2011.07.009 · Cited by 72
Internet-delivered CBT for children with specific phobia: a pilot study
Vigerland, S., Thulin, U., Ljótsson, B., Svirsky, L., Öst, L.-G., Lindefors, N., Andersson, G., & Serlachius, E. (2013) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2013.844201 · Cited by 67
Schwartz, C., Schlegl, S., Kuelz, A. K., & Voderholzer, U. (2013) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2013.10.006 · Cited by 60
Lewin, A. B., Peris, T. S., Nadai, A. S. D., McCracken, J. T., & Piacentini, J. C. (2012) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0029991 · Cited by 51
Clinicians’ views on management of obsessive–compulsive disorders in children and adolescents
Valderhaug, R., Götestam, K. G., & Larsson, B. S. (2004) · Nordic Journal of Psychiatry · doi:10.1080/08039480410005503 · Cited by 50
Do it yourself? Self-help and online therapy for people with obsessive-compulsive disorder
Moritz, S., Wittekind, C. E., Hauschildt, M., & Timpano, K. (2011) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32834abb7f · Cited by 47
Salloum, A. (2010) · Professional Psychology Research and Practice · doi:10.1037/a0018330 · Cited by 33
Ivarsson, T., Thomsen, P. H., Dahl, K., Valderhaug, R., Weidle, B., Nissen, J. B., Englyst, I., Christensen, K., Torp, N. C., & Melin, K. (2010) · Child & Youth Care Forum · doi:10.1007/s10566-010-9097-3 · Cited by 26
Children’s Depression Inventory (CDI)
(2011) · Encyclopedia of Child Behavior and Development · doi:10.1007/978-0-387-79061-9_4285 · Cited by 5
Cited by
Sorted by citations
Vigerland, S., Lenhard, F., Bonnert, M., Lalouni, M., Hedman, E., Ahlen, J., Olén, O., Serlachius, E., & Ljótsson, B. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2016.09.005 · Cited by 292
“Four of the included studies were written by coauthors of this review (Bonnert et al., 2014; Lenhard et al., 2014; Vigerland et al., 2013; Vigerland et al., 2016).”
BackgroundSelf-citationRemote cognitive-behavior therapy for obsessive-compulsive symptoms: A meta-analysis.
Wootton, B. M. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2015.10.001 · Cited by 162
Obsessive-compulsive disorder in children and adolescents
Krebs, G., & Heyman, I. (2009) · Archives of Disease in Childhood · doi:10.1136/archdischild-2014-306934 · Cited by 304
Lenhard, F., Andersson, E., Mataix-Cols, D., Rück, C., Vigerland, S., Högström, J., Hillborg, M., Brander, G., Ljungström, M., Ljótsson, B., et al. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2016.09.515 · Cited by 146
Neuroscience-informed psychoeducation for addiction medicine: A neurocognitive perspective
Ekhtiari, H., Rezapour, T., Aupperle, R. L., & Paulus, M. P. (2017) · Progress in brain research · doi:10.1016/bs.pbr.2017.08.013 · Cited by 134
Metadata
- Authors
- Lenhard, F., Vigerland, S., Andersson, E., Rück, C., Mataix-Cols, D., Thulin, U., Ljótsson, B., & Serlachius, E.
- Affiliations
- Karolinska Institutet (SE)
- Corresponding author
- Lenhard, Fabian
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-06-20
- Volume
- 9
- Issue
- 6
- Pages
- e100773
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4065049
- OpenAlex
- W2116170399
- Cited by
- 104
- References
- 66
- Citations by year
- 2025: 1 · 2024: 9 · 2023: 3 · 2022: 8 · 2021: 21 · 2020: 5 · 2019: 10 · 2018: 7 · 2017: 16 · 2016: 12 · 2015: 10 · 2014: 2
- FWCI
- 20.73
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Funders
- Karolinska Institutet
- Stockholms Läns Landsting (20120167)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- internet-based cognitive behavioral therapy, obsessive-compulsive disorder, adolescents, pediatric OCD, treatment acceptability, treatment efficacy, treatment feasibility, Children's Yale-Brown Obsessive Compulsive Scale, parental involvement
- MeSH terms
- Adolescent, Child, Female, Humans, Male, Obsessive-Compulsive Disorder, Parents, Severity of Illness Index, Cognitive Behavioral Therapy, Treatment Outcome, Telemedicine, Internet
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review