CoChat
Sign Up
Cited by 63

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine

van Gijsel-Bonnello, Manuel, Baranger, Kévin, Benech, Philippe, Rivera, Santiago, Khrestchatisky, Michel, de Reggi, Max, Gharib, Bouchra·2017·PLOS ONE
DOI 10.1371/journal.pone.0175369PMC PMC5391924
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1371/journal.pone.0175369

Cites

13 of 13 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 53

  1. J Zhao, 2011, The contribution of activated astrocytes to Abeta production: implications for Alzheimer's disease pathogenesis, J Neuroinflammation, 8, 150, 10.1186/1742-2094-8-150 · DOI
  2. HS Hong, 2003, Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes, Biochem Biophys Res Commun, 307, 922, 10.1016/S0006-291X(03)01270-1 · DOI · Paper page
  3. M Orre, 2014, Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction, Neurobiol Aging, 35, 2746, 10.1016/j.neurobiolaging.2014.06.004 · DOI · Paper page
  4. T Iram, 2016, Astrocytes from old Alzheimer's disease mice are impaired in Abeta uptake and in neuroprotection, Neurobiol Dis, 96, 84, 10.1016/j.nbd.2016.08.001 · DOI
  5. G Wang, 2008, Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes, Glia, 56, 449, 10.1002/glia.20626 · DOI
  6. LH Nilsen, 2014, Neuronal and astrocytic metabolism in a transgenic rat model of Alzheimer's disease, J Cereb Blood Flow Metab, 34, 906, 10.1038/jcbfm.2014.37 · DOI
  7. J Xu, 2016, Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder, Biochim Biophys Acta, 1862, 1084, 10.1016/j.bbadis.2016.03.001 · DOI
  8. HM Wilkins, 2016, Relationships Between Mitochondria and Neuroinflammation: Implications for Alzheimer's Disease, Curr Top Med Chem, 16, 849, 10.2174/1568026615666150827095102 · DOI
  9. W Zhang, 2012, Multiple inflammatory pathways are involved in the development and progression of cognitive deficits in APPswe/PS1dE9 mice, Neurobiol Aging, 33, 2661, 10.1016/j.neurobiolaging.2011.12.023 · DOI
  10. AS Lanzrein, 1998, Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-alpha, the soluble tumor necrosis factor receptors I and II, and alpha1-antichymotrypsin, Alzheimer Dis Assoc Disord, 12, 215, 10.1097/00002093-199809000-00016 · DOI
  11. MA Lynch, 1998, Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1 beta?, Prog Neurobiol, 56, 571, 10.1016/S0301-0082(98)00054-9 · DOI
  12. K Morimoto, 2011, Expression profiles of cytokines in the brains of Alzheimer's disease (AD) patients compared to the brains of non-demented patients with and without increasing AD pathology, J Alzheimers Dis, 25, 59, 10.3233/JAD-2011-101815 · DOI
  13. K Baranger, 2016, MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease, Cell Mol Life Sci, 73, 217, 10.1007/s00018-015-1992-1 · DOI · Paper page
  14. NA Py, 2014, Differential spatio-temporal regulation of MMPs in the 5xFAD mouse model of Alzheimer's disease: evidence for a pro-amyloidogenic role of MT1-MMP, Front Aging Neurosci, 6, 247
  15. J Hardy, 2002, The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics, Science, 297, 353, 10.1126/science.1072994 · DOI · Paper page
  16. CJ Garwood, 2011, Astrocytes are important mediators of Abeta-induced neurotoxicity and tau phosphorylation in primary culture, Cell Death Dis, 2, e167, 10.1038/cddis.2011.50 · DOI · Paper page
  17. EE Tuppo, 2005, The role of inflammation in Alzheimer's disease, Int J Biochem Cell Biol, 37, 289, 10.1016/j.biocel.2004.07.009 · DOI · Paper page
  18. L Hou, 2011, The effects of amyloid-beta42 oligomer on the proliferation and activation of astrocytes in vitro, In Vitro Cell Dev Biol Anim, 47, 573, 10.1007/s11626-011-9439-y · DOI
  19. P Narayan, 2014, Rare individual amyloid-beta oligomers act on astrocytes to initiate neuronal damage, Biochemistry, 53, 2442, 10.1021/bi401606f · DOI
  20. D Schubert, 2009, The induction of HIF-1 reduces astrocyte activation by amyloid beta peptide, Eur J Neurosci, 29, 1323, 10.1111/j.1460-9568.2009.06712.x · DOI
  21. T Soucek, 2003, The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide, Neuron, 39, 43, 10.1016/S0896-6273(03)00367-2 · DOI · Paper page
  22. D Brunetti, 2013, Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model, Brain, 137, 57, 10.1093/brain/awt325 · DOI
  23. E Cornille, 2010, Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury, BMC Neurosci, 11, 51, 10.1186/1471-2202-11-51 · DOI
  24. A Rana, 2010, Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration, Proc Natl Acad Sci U S A, 107, 6988, 10.1073/pnas.0912105107 · DOI
  25. M Rothmann, 2013, Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A, J Am Chem Soc, 135, 5962, 10.1021/ja400795m · DOI
  26. N Kavian, 2015, Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding, Arthritis Rheumatol, 67, 1881, 10.1002/art.39121 · DOI
  27. MF Penet, 2008, Protection against cerebral malaria by the low-molecular-weight thiol pantethine, Proc Natl Acad Sci U S A, 105, 1321, 10.1073/pnas.0706867105 · DOI
  28. C Ogier, 2005, Astrocyte reactivity to Fas activation is attenuated in TIMP-1 deficient mice, an in vitro study, BMC Neurosci, 6, 68, 10.1186/1471-2202-6-68 · DOI · Paper page
  29. O Sbai, 2010, Differential vesicular distribution and trafficking of MMP-2, MMP-9, and their inhibitors in astrocytes, Glia, 58, 344, 10.1002/glia.20927 · DOI
  30. M van Gijsel-Bonnello, 2015, Pantethine Alters Lipid Composition and Cholesterol Content of Membrane Rafts, With Down-Regulation of CXCL12-Induced T Cell Migration, J Cell Physiol
  31. RC Stanton, 1991, Rapid release of bound glucose-6-phosphate dehydrogenase by growth factors. Correlation with increased enzymatic activity, J Biol Chem, 266, 12442, 10.1016/S0021-9258(18)98918-0 · DOI
  32. Z Zhang, 2000, A method for determination of pyridine nucleotides using a single extract, Anal Biochem, 285, 163, 10.1006/abio.2000.4701 · DOI
  33. AS Almeida, 2012, Carbon monoxide modulates apoptosis by reinforcing oxidative metabolism in astrocytes: role of Bcl-2, J Biol Chem, 287, 10761, 10.1074/jbc.M111.306738 · DOI
  34. SW Sauer, 2005, Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A, J Biol Chem, 280, 21830, 10.1074/jbc.M502845200 · DOI
  35. MA Birch-Machin, 2001, Assaying mitochondrial respiratory complex activity in mitochondria isolated from human cells and tissues, Methods Cell Biol, 65, 97, 10.1016/S0091-679X(01)65006-4 · DOI
  36. Y Liu, 1997, Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction, J Neurochem, 69, 581, 10.1046/j.1471-4159.1997.69020581.x · DOI
  37. AF Kisselev, 2005, Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates, Methods Enzymol, 398, 364, 10.1016/S0076-6879(05)98030-0 · DOI
  38. P Jaakkola, 2001, Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation, Science, 292, 468, 10.1126/science.1059796 · DOI · Paper page
  39. R Gonzalez-Dominguez, 2014, Region-specific metabolic alterations in the brain of the APP/PS1 transgenic mice of Alzheimer's disease, Biochim Biophys Acta, 1842, 2395, 10.1016/j.bbadis.2014.09.014 · DOI
  40. I Pedros, 2014, Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease, Biochim Biophys Acta, 1842, 1556, 10.1016/j.bbadis.2014.05.025 · DOI
  41. AK Bouzier-Sore, 2015, Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: relevance for neurodegeneration and aging, Front Aging Neurosci, 7, 89
  42. GE Gibson, 2000, The alpha-ketoglutarate dehydrogenase complex in neurodegeneration, Neurochem Int, 36, 97, 10.1016/S0197-0186(99)00114-X · DOI
  43. I Kaneko, 1995, Suppression of mitochondrial succinate dehydrogenase, a primary target of beta-amyloid, and its derivative racemized at Ser residue, J Neurochem, 65, 2585, 10.1046/j.1471-4159.1995.65062585.x · DOI
  44. Q Shi, 2011, Inactivation and reactivation of the mitochondrial alpha-ketoglutarate dehydrogenase complex, J Biol Chem, 286, 17640, 10.1074/jbc.M110.203018 · DOI
  45. I Allaman, 2010, Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability, J Neurosci, 30, 3326, 10.1523/JNEUROSCI.5098-09.2010 · DOI
  46. W Fu, 2015, Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity, J Biol Chem, 290, 12504, 10.1074/jbc.M114.618157 · DOI
  47. P Bahety, 2014, Metabotyping of docosahexaenoic acid—treated Alzheimer's disease cell model, PLoS One, 9, e90123, 10.1371/journal.pone.0090123 · DOI
  48. RM Pruss, 1979, Thy-1 antigen on astrocytes in long-term cultures of rat central nervous system, Nature, 280, 688, 10.1038/280688a0 · DOI
  49. M Stenovec, 2016, Expression of familial Alzheimer disease presenilin 1 gene attenuates vesicle traffic and reduces peptide secretion in cultured astrocytes devoid of pathologic tissue environment, Glia, 64, 317, 10.1002/glia.22931 · DOI
  50. D Aguirre-Rueda, 2015, WIN 55,212–2, agonist of cannabinoid receptors, prevents amyloid beta1-42 effects on astrocytes in primary culture, PLoS One, 10, e0122843, 10.1371/journal.pone.0122843 · DOI
  51. D Mechlovich, 2014, The novel multi-target iron chelator, M30 modulates HIF-1alpha-related glycolytic genes and insulin signaling pathway in the frontal cortex of APP/PS1 Alzheimer's disease mice, Curr Alzheimer Res, 11, 119, 10.2174/1567205010666131212112529 · DOI
  52. A Serra-Perez, 2010, Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolites, J Biol Chem, 285, 18217, 10.1074/jbc.M110.101048 · DOI
  53. PJ Kallio, 1999, Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway, J Biol Chem, 274, 6519, 10.1074/jbc.274.10.6519 · DOI

Cited by

Sorted by citations

Metadata

Authors
van Gijsel-Bonnello, M., Baranger, K., Benech, P., Rivera, S., Khrestchatisky, M., de Reggi, M., & Gharib, B.
ORCID
Gharib, Bouchra
Venue
PLOS ONE
Publisher
Public Library of Science (PLoS)
Published
2017-04-14
Volume
12
Issue
4
Pages
e0175369
ISSN
1932-6203
DOI
10.1371/journal.pone.0175369
PMC
PMC5391924
Cited by
63
References
13
Language
en
Update notices
correction (2018-03-14)
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
  • CNRS
  • Aix-Marseille Université
  • French National Agency for Research (ANR, PREVENTAD)
  • France Alzheimer grant
  • Fonds Européen de DéveloppementRégional” FEDER in PACA
  • A*MIDEX (Management de talents) A

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review