Estradiol or genistein prevent Alzheimer's disease-associated inflammation correlating with an increase PPARγ expression in cultured astrocytes

Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial

Writing Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889 · see citing works

A simplification of the protein assay method of Lowry et al. which is more generally applicable

Peterson, G. L. (1977) · Analytical Biochemistry · doi:10.1016/0003-2697(77)90043-4 · Cited by 8,531 · see citing works

Alzheimer's Disease: Genes, Proteins, and Therapy

Selkoe, D. J. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.741 · Cited by 6,063 · see citing works

Untitled work

Wyss-Coray (2006) · doi:10.1038/nm1484 · Cited by 1,284 · see citing works

Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

Smith, M. A., Richey Harris, P. L., Sayre, L. M., Beckman, J. S., & Perry, G. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-08-02653.1997 · Cited by 1,239 · see citing works

Neurotoxicity of a Fragment of the Amyloid Precursor Associated with Alzheimer's Disease

Yankner, B. A., Dawes, L. R., Fisher, S., Villa-Komaroff, L., Oster-Granite, M. L., & Neve, R. L. (1989) · Science · doi:10.1126/science.2474201 · Cited by 907 · see citing works

Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause

Rocca, W. A., Bower, J. H., Maraganore, D. M., Ahlskog, J. E., Grossardt, B. R., de Andrade, M., & Melton, L. J. (2007) · Neurology · doi:10.1212/01.wnl.0000276984.19542.e6 · Cited by 827 · see citing works

Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males

Borrás, C., Sastre, J., García-Sala, D., Lloret, A., Pallardó, F. V., & Viña, J. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01356-4 · Cited by 654 · see citing works

Inflammation and the Degenerative Diseases of Aging

McGeer, P. L., & McGeer, E. G. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1332.007 · Cited by 519 · see citing works

Alzheimer Disease and Oxidative Stress

Perry, G., Cash, A. D., & Smith, M. A. (2002) · BioMed Research International · doi:10.1155/s1110724302203010 · Cited by 455 · see citing works

Inhibition of Pro-inflammatory Markers in Primary Bone Marrow-Derived Mouse Macrophages by Naturally Occurring Flavonoids: Analysis of the Structure-Activity Relationship

Comalada, M., Ballester, I., Bailón, E., Sierra, S., Xaus, J., Gálvez, J., Medina, F. S. D., & Zarzuelo, A. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.07.016 · Cited by 440 · see citing works

Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms

Sastre, M., Klockgether, T., & Heneka, M. T. (2006) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2005.11.014 · Cited by 426 · see citing works

Estrogen receptor-α mediates the brain antiinflammatory activity of estradiol

Vegeto, E., Belcredito, S., Etteri, S., Ghisletti, S., Brusadelli, A., Meda, C., Krust, A., Dupont, S., Ciana, P., Chambon, P., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1531957100 · Cited by 384 · see citing works

Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ

Sastre, M., Dewachter, I., Rossner, S., Bogdanovic, N., Rosen, E., Borghgraef, P., Evert, B. O., Dumitrescu-Ozimek, L., Thal, D. R., Landreth, G., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503839103 · Cited by 373 · see citing works

β-Amyloid Stimulation of Inducible Nitric-oxide Synthase in Astrocytes Is Interleukin-1β- and Tumor Necrosis Factor-α (TNFα)-dependent, and Involves a TNFα Receptor-associated Factor- and NFκB-inducing Kinase-dependent Signaling Mechanism

Akama, K. T., & Eldik, L. J. V. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.11.7918 · Cited by 356 · see citing works

Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases

Vegeto, E., Benedusi, V., & Maggi, A. C. (2008) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2008.04.001 · Cited by 356 · see citing works

Causes of oxidative stress in Alzheimer disease

Zhu, X., Su, B., Wang, X., Smith, M. A., & Perry, G. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7218-4 · Cited by 336 · see citing works

Inflammaging as a prodrome to Alzheimer's disease

Giunta, B., Fernandez, F., Nikolic, W. V., Obregon, D., Rrapo, E., Town, T., & Tan, J. (2008) · Journal of Neuroinflammation · doi:10.1186/1742-2094-5-51 · Cited by 327 · see citing works

Peroxisome Proliferator-activated Receptor γ (PPARγ) as a Molecular Target for the Soy Phytoestrogen Genistein

Dang, Z.-C., Audinot, V., Papapoulos, S. E., Boutin, J. A., & Löwik, C. W. G. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209483200 · Cited by 323 · see citing works

PPARs in the brain

HENEKA, M., & LANDRETH, G. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2007.04.016 · Cited by 317 · see citing works

Effects of Combination Estrogen Plus Progestin Hormone Treatment on Cognition and Affect

Resnick, S. M., Maki, P. M., Rapp, S. R., Espeland, M. A., Brunner, R. L., Coker, L. H., Granek, I. A., Hogan, P. E., Ockene, J. K., & Shumaker, S. A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2097 · Cited by 309 · see citing works

Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes

Vallés, S. L., Blanco, A. M., Pascual, M., & Guerri, C. (2004) · Brain Pathology · doi:10.1111/j.1750-3639.2004.tb00079.x · Cited by 271 · see citing works

17β‐oestradiol up‐regulates longevity‐related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFκB cascade

Borrás, C., Gambini, J., Gómez-Cabrera, M. C., Sastre, J., Pallardó, F., Mann, G., & Viña, J. (2005) · Aging Cell · doi:10.1111/j.1474-9726.2005.00151.x · Cited by 257 · see citing works

Estrogen, cognition and female ageing

Genazzani, A. R., Pluchino, N., Luisi, S., & Luisi, M. (2007) · Human Reproduction Update · doi:10.1093/humupd/dml042 · Cited by 237 · see citing works

Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation.

Lüth, H., Münch, G., & Arendt, T. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03280-8 · Cited by 233 · see citing works

Estrogen Modulates Microglial Inflammatory Mediator Production via Interactions with Estrogen Receptor β

Baker, A. E., Brautigam, V. M., & Watters, J. J. (2004) · Endocrinology · doi:10.1210/en.2004-0619 · Cited by 227 · see citing works

Inflammation, anti-inflammatory agents and Alzheimer disease: The last 12 years

McGeer, P. L., Rogers, J., & McGeer, E. G. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-9s330 · Cited by 222 · see citing works

Dietary soy isoflavone‐induced increases in antioxidant and eNOS gene expression lead to improved endothelial function and reduced blood pressure in vivo

Mahn, K., Borrás, C., Knock, G., Taylor, P., Khan, I. Y., Sugden, D., Poston, L., Ward, J., Sharpe, R., Viña, J., et al. (2005) · The FASEB Journal · doi:10.1096/fj.05-4008fje · Cited by 201 · see citing works

Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer’s disease, in APP23 transgenic mice and after experimental brain lesion in rat: Evidence for an induction by amyloid pathology

Lüth, H.-J., Holzer, M., Gärtner, U., Staufenbiel, M., & Arendt, T. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02758-5 · Cited by 183 · see citing works

Genistein, a soy isoflavone, up‐regulates expression of antioxidant genes: involvement of estrogen receptors, ERK1/2, and NFκB

Borrás, C., Gambini, J., Gómez‐Cabrera, M. C., Sastre, J., Pallardó, F. V., Mann, G. E., & Viña, J. (2006) · The FASEB Journal · doi:10.1096/fj.05-5522fje · Cited by 180 · see citing works

Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity

Bang, O. Y., Hong, H., Kim, D. H., Kim, H., Boo, J. H., Huh, K., & Mook‐Jung, I. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2003.12.017 · Cited by 123 · see citing works

PPARs as Drug Targets to Modulate Inflammatory Responses?

Genolet, R., Wahli, W., & Michalik, L. (2004) · Current Drug Targets - Inflammation & Allergy · doi:10.2174/1568010042634578 · Cited by 119 · see citing works

Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-γ-induced IκB degradation in RAW264.7 macrophages

Murakami, A., Matsumoto, K., Koshimįzu, K., & Ohigashi, H. (2003) · Cancer Letters · doi:10.1016/s0304-3835(03)00058-2 · Cited by 114 · see citing works

Role of astrocytes in estrogen-mediated neuroprotection

Dhandapani, K. M., & Brann, D. W. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2006.06.032 · Cited by 105 · see citing works

Oestradiol or genistein rescues neurons from amyloid beta‐induced cell death by inhibiting activation of p38

Vallés, S. L., Borrás, C., Gambini, J., Furriol, J., Ortega, Á., Sastre, J., Pallardó, F. V., & Viña, J. (2007) · Aging Cell · doi:10.1111/j.1474-9726.2007.00356.x · Cited by 81 · see citing works

Estrogen-induced Production of a Peroxisome Proliferator-activated Receptor (PPAR) Ligand in a PPARγ-expressing Tissue

Ma, H., Sprecher, H. W., & Kolattukudy, P. E. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.46.30131 · Cited by 72 · see citing works

Effects of the β-Amyloid and Carboxyl-terminal Fragment of Alzheimer's Amyloid Precursor Protein on the Production of the Tumor Necrosis Factor-α and Matrix Metalloproteinase-9 by Human Monocytic THP-1

Chong, Y. H., Sung, J. H., Shin, S. A., Chung, J., & Suh, Y. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009466200 · Cited by 65 · see citing works

The inflammatory process in aging

Yu, B. P., & Chung, H. Y. (2006) · Reviews in Clinical Gerontology · doi:10.1017/s0959259807002110 · Cited by 65 · see citing works

Chronic Ethanol Consumption Enhances Interleukin‐1‐Mediated Signal Transduction in Rat Liver and in Cultured Hepatocytes

Vallés, S. L., Blanco, A. M. A., Azorı́n, I., Guasch, R. M., Pascual, M., Gómez-Lechón, M. J., Renau‐Piqueras, J., & Guerri, C. (2003) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000099261.87880.21 · Cited by 64 · see citing works

The peroxisome proliferator-activated receptor gamma (PPAR-γ2) Pro12Ala polymorphism is associated with higher risk for Alzheimer's disease in octogenarians

Scacchi, R., Pinto, A., Gambina, G., Rosano, A., & Corbo, R. M. (2007) · Brain Research · doi:10.1016/j.brainres.2006.12.078 · Cited by 38 · see citing works

Inhibition of hemolysate-induced iNOS and COX-2 expression by genistein through suppression of NF-кB activation in primary astrocytes

Lu, H., Shi, J., Zhang, D., Wang, H., Hang, C., Chen, H., & Yin, H.-X. (2009) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2008.12.007 · Cited by 35 · see citing works

Association Analysis of Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Late Onset Alzheimer’s Disease in the Finnish Population

Koivisto, A. M., Helisalmi, S., Pihlajamäki, J., Hiltunen, M., Koivisto, K. J., Moilanen, L., Kuusisto, J., Helkala, E., Hänninen, T., Kervinen, K., et al. (2006) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000095857 · Cited by 32 · see citing works

Pioglitazone, a PPARγ ligand, suppresses NFκB activation through inhibition of IκB kinase activation in cerulein-treated AR42J cells

Wan, H., Yuan, Y., Qian, A., Sun, Y., & Qiao, M.-M. (2007) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2007.10.012 · Cited by 29 · see citing works

Estrogenic compounds inhibit gap junctional intercellular communication in mouse Leydig TM3 cells

IWASE, Y., Fukata, H., & Mori, C. (2005) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2005.08.005 · Cited by 13 · see citing works

Antitumor effect of methylglyoxal bis(butylamidinohydrazone), a new inhibitor of S-adenosylmethionine decarboxylase, against human erythroid leukemia K 562 cells

Hibasami, H., Tsukada, T., Maekawa, S., & Nakashima, K. (1986) · Cancer Letters · doi:10.1016/0304-3835(86)90127-8 · Cited by 9 · see citing works

Anti-inflammatory activity of natural dietary flavonoids

Pan, M., Lai, C., & Ho, C. (2010) · Food & Function · doi:10.1039/c0fo00103a · Cited by 612 · see citing works

Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials

Jantan, I., Ahmad, W., & Bukhari, S. N. A. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00655 · Cited by 412 · see citing works

Why Women Have More Alzheimer's Disease Than Men: Gender and Mitochondrial Toxicity of Amyloid-β Peptide

Viña, J., & Lloret, A. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100501 · Cited by 447 · see citing works

Neuroinflammation: Modulation by flavonoids and mechanisms of action

Spencer, J. P. E., Vafeiadou, K., Williams, R. J., & Vauzour, D. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2011.10.016 · Cited by 315 · see citing works

Memantine loaded PLGA PEGylated nanoparticles for Alzheimer’s disease: in vitro and in vivo characterization

Sánchez‐López, E., Ettcheto, M., Egea, M. A., Espina, M., Cano, A. C., Calpena, A. C., Camins, A., Carmona-Ule, N., Silva, A. M., Souto, E. B., et al. (2018) · Journal of Nanobiotechnology · doi:10.1186/s12951-018-0356-z · Cited by 297 · see citing works

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer’s disease

Seo, E.-J., Fischer, N., & Efferth, T. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2017.11.030 · Cited by 265 · see citing works

Genistein: Its role in metabolic diseases and cancer

Mukund, V., Mukund, D., Sharma, V., Mannarapu, M., & Alam, A. (2017) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2017.09.004 · Cited by 248 · see citing works

Genistein ameliorates learning and memory deficits in amyloid β(1–40) rat model of Alzheimer’s disease

Bagheri, M., Joghataei, M. T., Mohseni, S., & Roghani, M. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.12.001 · Cited by 247 · see citing works

Neurosteroids as regulators of neuroinflammation

Yılmaz, C., Karali, K., Fodelianaki, G., Gravanis, A., Chavakis, T., Charalampopoulos, I., & Alexaki, V. I. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100788 · Cited by 245 · see citing works

Naturally derived anti-inflammatory compounds from Chinese medicinal plants

Wang, Q., Kuang, H., Su, Y., Sun, Y., Feng, J., Guo, R., & Chan, K. (2012) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2012.12.013 · Cited by 241 · see citing works

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

Ming, L., Chen, K., & Xian, C. J. (2012) · Journal of Cellular Physiology · doi:10.1002/jcp.24158 · Cited by 218 · see citing works

Impact of Cytokines and Chemokines on Alzheimer’s Disease Neuropathological Hallmarks

Domingues, C., Silva, O. A. B. D. C. E., & Henriques, A. G. (2017) · Current Alzheimer Research · doi:10.2174/1567205014666170317113606 · Cited by 212 · see citing works

Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer’s disease: A neuropharmacological review of their bioactive constituents

Gorji, N., Moeini, R., & Memariani, Z. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.12.003 · Cited by 154 · see citing works

Adaptive Cellular Stress Pathways as Therapeutic Targets of Dietary Phytochemicals: Focus on the Nervous System

Lee, J., Jo, D., Park, D., Chung, H. Y., & Mattson, M. P. (2014) · Pharmacological Reviews · doi:10.1124/pr.113.007757 · Cited by 154 · see citing works

Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown

Moreira, A. C., Silva, A. M., Santos, M. S., & Sardão, V. A. (2014) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.01.016 · Cited by 127 · see citing works

Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions

Acaz‐Fonseca, E., Ávila-Rodriguez, M., García‐Segura, L. M., & Barreto, G. E. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.06.002 · Cited by 126 · see citing works

Emerging Signal Regulating Potential of Genistein Against Alzheimer’s Disease: A Promising Molecule of Interest

Uddin, M. S., & Kabir, M. T. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00197 · Cited by 119 · see citing works

Intracellular Signaling Pathways Modulated by Phenolic Compounds: Application for New Anti-Inflammatory Drugs Discovery

Costa, G., Francisco, V., Lopes, M. C., Cruz, M. T., & Batista, M. T. (2012) · Current Medicinal Chemistry · doi:10.2174/092986712800672049 · Cited by 113 · see citing works

Role of astrocytes in the neuroprotective actions of 17β-estradiol and selective estrogen receptor modulators

Acaz‐Fonseca, E., Sánchez‐González, R., Azcoitia, Í., Arévalo, M., & García‐Segura, L. M. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.01.009 · Cited by 104 · see citing works

Clearing Amyloid-β through PPARγ/ApoE Activation by Genistein is a Treatment of Experimental Alzheimer’s Disease

Bonet-Costa, V., Herranz‐Pérez, V., Blanco-Gandía, M. C., Mas‐Bargues, C., Inglés, M., García-Tárraga, P., Rodríguez‐Arias, M., Miñarro, J., Borrás, C., García‐Verdugo, J. M., et al. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-151020 · Cited by 103 · see citing works

Fermented Soy Products: Beneficial Potential in Neurodegenerative Diseases

Jang, C. H., Oh, J., Lim, J. S., Kim, H. J., & Kim, J.-S. (2021) · Foods · doi:10.3390/foods10030636 · Cited by 100 · see citing works

Selective Oestrogen Receptor Modulators Decrease the Inflammatory Response of Glial Cells

Arévalo, M., Diz-Chaves, Y., Santos‐Galindo, M., Bellini, M. J., & García‐Segura, L. M. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02156.x · Cited by 98 · see citing works

Molecular and Therapeutic Targets of Genistein in Alzheimer’s Disease

Devi, K. P., Shanmuganathan, B., Manayi, A., Nabavi, S. F., & Nabavi, S. M. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0215-6 · Cited by 96 · see citing works

PPAR Agonists as Therapeutics for CNS Trauma and Neurological Diseases

Mandrekar-Colucci, S., Sauerbeck, A. D., Popovich, P. G., & McTigue, D. M. (2013) · ASN NEURO · doi:10.1042/an20130030 · Cited by 91 · see citing works

Genistein Antagonizes Inflammatory Damage Induced by β-amyloid Peptide in Microglia through TLR4 and NF-Κb

Zhou, X., Yuan, L., Zhao, X., Hou, C., Ma, W., Yu, H., & Xiao, R. (2014) · Nutrition · doi:10.1016/j.nut.2013.06.006 · Cited by 89 · see citing works

Astrocytes Protect Neurons from Aβ1-42 Peptide-Induced Neurotoxicity Increasing TFAM and PGC-1 and Decreasing PPAR-γ and SIRT-1

Aguirre-Rueda, D., Guerra‐Ojeda, S., Aldasoro, M., Iradi, A., Obrador, E., Ortega, Á., Mauricio, M. D., Vila, J. M., & Vallés, S. L. (2014) · International Journal of Medical Sciences · doi:10.7150/ijms.10035 · Cited by 84 · see citing works

Genistein Inhibits Osteoclastic Differentiation of RAW 264.7 Cells via Regulation of ROS Production and Scavenging

Lee, S., Kim, J., & Jang, H. D. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms150610605 · Cited by 80 · see citing works

Study on the neuroprotective effects of Genistein on Alzheimer’s disease

Duan, X., Li, Y., Xu, F., & Ding, H. (2021) · Brain and Behavior · doi:10.1002/brb3.2100 · Cited by 78 · see citing works

Astrocytes and Microglia: Responses to Neuropathological Conditions

Singh, S., Swarnkar, S., Goswami, P., & Nath, C. (2011) · International Journal of Neuroscience · doi:10.3109/00207454.2011.598981 · Cited by 77 · see citing works

Isoflavones, Genistein and Daidzein, Regulate Mucosal Immune Response by Suppressing Dendritic Cell Function

Wei, J., Bhatt, S., Chang, L. M., Sampson, H. A., & Masilamani, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047979 · Cited by 76 · see citing works

Therapeutic Potential of Phytoconstituents in Management of Alzheimer’s Disease

Singh, S. P., Nand, S., Maurya, A., Mishra, G., Awasthi, R., Shakya, A., Chellappan, D. K., Dua, K., Vamanu, E., Chaudhary, S. K., et al. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/5578574 · Cited by 75 · see citing works

Functions of Astrocytes under Normal Conditions and after a Brain Disease

Vallés, S. L., Singh, S. K., Campos-Campos, J., Colmena, C., Campo-Palacio, I., Alvarez-Gamez, K., Caballero, Ó., & Jorda, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098434 · Cited by 76 · see citing works

Therapeutic potential of quinazoline derivatives for Alzheimer's disease: A comprehensive review

Haghighijoo, Z., Zamani, L., Moosavi, F., & Emami, S. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.113949 · Cited by 75 · see citing works

Genistein effect on cognition in prodromal Alzheimer’s disease patients. The GENIAL clinical trial

Viña, J., Escudero, J. V., Baquero, M., Cebrián, M., Carbonell‐Asins, J. A., Muñoz, J. E., Satorres, E., Meléndez, J. C., Ferrer-Rebolleda, J., Cozar, M., et al. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-01097-2 · Cited by 74 · see citing works

Role of astroglia in the neuroplastic and neuroprotective actions of estradiol

Azcoitia, Í., Santos‐Galindo, M., Arévalo, M., & García‐Segura, L. M. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07516.x · Cited by 72 · see citing works

Exploring the Therapeutic Potential of Phytochemicals in Alzheimer’s Disease: Focus on Polyphenols and Monoterpenes

Piccialli, I., Tedeschi, V., Caputo, L., D’Errico, S., Ciccone, R., De Feo, V., Secondo, A., & Pannaccione, A. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.876614 · Cited by 73 · see citing works

Alzheimer’s disease and neuroinflammation: will new drugs in clinical trials pave the way to a multi-target therapy?

Melchiorri, D., Merlo, S., Micallef, B., Borg, J.-J., & Dráfi, F. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1196413 · Cited by 72 · see citing works

Effects and Underlying Mechanisms of Bioactive Compounds on Type 2 Diabetes Mellitus and Alzheimer’s Disease

Li, R., Zhang, Y., Rasool, S., Geetha, T., & Babu, J. R. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/8165707 · Cited by 72 · see citing works

Potential Therapeutic Role of Phytochemicals to Mitigate Mitochondrial Dysfunctions in Alzheimer’s Disease

Rahman, M. A., Rahman, M. H., Biswas, P., Hossain, M. S., Islam, R., Hannan, M. A., Uddin, M. J., & Rhim, H. (2020) · Antioxidants · doi:10.3390/antiox10010023 · Cited by 70 · see citing works

Trigonelline protects hippocampus against intracerebral Aβ(1–40) as a model of Alzheimer’s disease in the rat: insights into underlying mechanisms

Babaei, J. F., Baluchnejadmojarad, T., Nikbakht, F., & Roghani, M. (2018) · Metabolic Brain Disease · doi:10.1007/s11011-018-0338-8 · Cited by 71 · see citing works

Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine

van Gijsel‐Bonnello, M., Baranger, K., Benech, P. D., Rivera, S., Khrestchatisky, M., Reggi, M. L. D., & Gharib, B. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175369 · Cited by 68 · see citing works

Administration of 17β-Estradiol Improves Motoneuron Survival and Down-regulates Inflammasome Activation in Male SOD1(G93A) ALS Mice

Heitzer, M., Kaiser, S., Kanagaratnam, M., Zendedel, A., Hartmann, P., Beyer, C., & Johann, S. (2017) · Molecular Neurobiology · doi:10.1007/s12035-016-0322-4 · Cited by 69 · see citing works

Diet and Inflammation in Alzheimer’s Disease and Related Chronic Diseases: A Review

Gardener, S. L., Rainey‐Smith, S. R., & Martins, R. N. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150765 · Cited by 62 · see citing works

WIN 55,212-2, Agonist of Cannabinoid Receptors, Prevents Amyloid β1-42 Effects on Astrocytes in Primary Culture

Aguirre-Rueda, D., Guerra‐Ojeda, S., Aldasoro, M., Iradi, A., Obrador, E., Mauricio, M. D., Vila, J. M., Marchio, P., & Vallés, S. L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0122843 · Cited by 64 · see citing works

Tryptophan Metabolism in Alzheimer’s Disease with the Involvement of Microglia and Astrocyte Crosstalk and Gut-Brain Axis

Xie, L., Wu, Q., Li, K., Khan, M. A. S., Zhang, A., Sinha, B., Li, S., Chang, S. L., Brody, D. L., Grinstaff, M. W., et al. (2024) · Aging and Disease · doi:10.14336/ad.2024.0134 · Cited by 63 · see citing works

Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury

Zhang, T., Wang, F., Xu, H., Yi, L., Qin, Y., Chang, H., Mi, M., & Zhang, Q. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001110 · Cited by 62 · see citing works

Magnesium ion influx reduces neuroinflammation in Aβ precursor protein/Presenilin 1 transgenic mice by suppressing the expression of interleukin-1β

Wang, P., Yu, X., Guan, P.-P., Guo, J., Wang, Y., Zhang, Y., Zhao, H., & Wang, Z. (2015) · Cellular and Molecular Immunology · doi:10.1038/cmi.2015.93 · Cited by 61 · see citing works

Epigallocatechin Gallate Attenuates β-Amyloid Generation and Oxidative Stress Involvement of PPARγ in N2a/APP695 Cells

Zhang, Z.-X., Li, Y., & Zhao, R. (2016) · Neurochemical Research · doi:10.1007/s11064-016-2093-8 · Cited by 60 · see citing works

Precision medicine and drug development in Alzheimer’s disease: the importance of sexual dimorphism and patient stratification

Hampel, H., Vergallo, A., Giorgi, F. S., Kim, S. H., Depypere, H., Graziani, M., Saidi, A., Nisticò, R., & Lista, S. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.06.001 · Cited by 68 · see citing works

The multimodal action of genistein in Alzheimer's and other age-related diseases

Mas‐Bargues, C., Borrás, C., & Viña, J. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.03.021 · Cited by 59 · see citing works

Lipocalin 2 Deficiency Alters Estradiol Production and Estrogen Receptor Signaling in Female Mice

Guo, H., Zhang, Y., Brockman, D. A., Hahn, W. S., Bernlohr, D., & Chen, X. (2012) · Endocrinology · doi:10.1210/en.2011-1642 · Cited by 59 · see citing works

Gliotoxicity and Glioprotection: the Dual Role of Glial Cells

Quincozes‐Santos, A., Santos, C. L., Almeida, R. R. D. S., da Silva, A., Thomaz, N. K., Costa, N. L. F., Weber, F. B., Schmitz, I., Medeiros, L. S., Medeiros, L., et al. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02574-9 · Cited by 57 · see citing works

Two-year follow-up of Sanfilippo Disease patients treated with a genistein-rich isoflavone extract: Assessment of effects on cognitive functions and general status of patients

Piotrowska, E., Jakóbkiewicz‐Banecka, J., Maryniak, A., Tylki‐Szymańska, A., Puk, E., Liberek, A., Węgrzyn, A., Czartoryska, B., Słomińska-Wojewódzka, M., & Węgrzyn, G. (2011) · Medical Science Monitor · doi:10.12659/msm.881715 · Cited by 57 · see citing works

Natural Compounds with Anti-BACE1 Activity as Promising Therapeutic Drugs for Treating Alzheimerʼs Disease

Naushad, M., Durairajan, S. S. K., Bera, A. K., Senapati, S., & Li, M. (2019) · Planta Medica · doi:10.1055/a-1019-9819 · Cited by 59 · see citing works

Genistein protects against amyloid‐beta‐induced toxicity in SH‐SY5Y cells by regulation of Akt and Tau phosphorylation

Petry, F. D. S., Coelho, B. P., Gaelzer, M. M., Kreutz, F., Guma, F. T. C. R., Salbego, C. G., & Trindade, V. M. T. (2019) · Phytotherapy Research · doi:10.1002/ptr.6560 · Cited by 57 · see citing works

Neuroinflammation in pathogenesis of Alzheimer’s disease: Phytochemicals as potential therapeutics

Vaiserman, A. M., Koliada, A. K., & Lushchak, O. V. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111259 · Cited by 57 · see citing works

Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates

Duro‐Castaño, A., Borrás, C., Herranz‐Pérez, V., Blanco-Gandía, M. C., Conejos‐Sánchez, I., Armiñán, A., Mas‐Bargues, C., Inglés, M., Miñarro, J., Rodríguez‐Arias, M., et al. (2021) · Science Advances · doi:10.1126/sciadv.abf9180 · Cited by 56 · see citing works

Genistein: A focus on several neurodegenerative diseases

Li, R., Robinson, M., Ding, X.-W., Geetha, T., Al‐Nakkash, L., Broderick, T. L., & Babu, J. R. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14155 · Cited by 56 · see citing works

Genistein inhibits aggregation of exogenous amyloid-beta1–40 and alleviates astrogliosis in the hippocampus of rats

Bagheri, M., Roghani, M., Joghataei, M. T., & Mohseni, S. (2011) · Brain Research · doi:10.1016/j.brainres.2011.10.020 · Cited by 56 · see citing works

Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells

Báez-Jurado, E., Rincon‐Benavides, M. A., Hidalgo‐Lanussa, O., Guio-Vega, G. P., Ashraf, G. M., Sahebkar, A., Echeverrı́a, V., García‐Segura, L. M., & Barreto, G. E. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.09.001 · Cited by 62 · see citing works

Genistein Attenuates Brain Damage induced by Transient Cerebral Ischemia Through Up-regulation of ERK Activity in Ovariectomized Mice

Wang, S., Wei, H., Cai, M., Lu, Y., Hou, W., Yang, Q., Dong, H., & Xiong, L. (2014) · International Journal of Biological Sciences · doi:10.7150/ijbs.7562 · Cited by 53 · see citing works

Genistein alleviates the mitochondria-targeted DNA damage induced by β-amyloid peptides 25–35 in C6 glioma cells

Ma, W., Hou, C.-C., Zhou, X. J., Yu, H., Xi, Y., Ding, J., Zhao, X., & Xiao, R. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1019-y · Cited by 50 · see citing works

Neuroprotective Effects of Genistein in Mongolian Gerbils: Estrogen Receptor–β Involvement

Donzelli, A., Braida, D., Finardi, A., Capurro, V., Valsecchi, A. E., Colleoni, M., & Sala, M. (2010) · Journal of Pharmacological Sciences · doi:10.1254/jphs.10164fp · Cited by 50 · see citing works

The Role of Estradiol in Traumatic Brain Injury: Mechanism and Treatment Potential

Kövesdi, E., Szabó‐Meleg, E., & Ábrahám, I. M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010011 · Cited by 50 · see citing works

Anti-Neuroinflammatory Potential of Polyphenols by Inhibiting NF-Κb to Halt Alzheimer's Disease

Uddin, M. S., Hasana, S., Ahmad, J., Hossain, M. F., Rahman, M. M., Behl, T., Rauf, A., Ahmad, A., Hafeez, A., Perveen, A., et al. (2021) · Current Pharmaceutical Design · doi:10.2174/1381612826666201118092422 · Cited by 49 · see citing works

Neuroprotective potentials of Lead phytochemicals against Alzheimer's disease with focus on oxidative stress-mediated signaling pathways: Pharmacokinetic challenges, target specificity, clinical trials and future perspectives

Ayaz, M., Mosa, O. F., Nawaz, A., Hamdoon, A. A. E., Elkhalifa, M. E. M., Sadiq, A., Ullah, F., Ahmed, A., Kabra, A., Khan, H. Z., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.155272 · Cited by 49 · see citing works

Exploring the Contribution of Estrogen to Amyloid-Beta Regulation: A Novel Multifactorial Computational Modeling Approach

Anastasio, T. J. (2013) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00016 · Cited by 49 · see citing works

Interplay between SOX9, β-catenin and PPARγ activation in colorectal cancer

Panza, A., Pazienza, V., Ripoli, M. C., Benegiamo, G., Gentile, A., Valvano, M. R., Augello, B., Merla, G., Prattichizzo, C., Tavano, F., et al. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.04.004 · Cited by 47 · see citing works

Changes in Chemokines and Chemokine Receptors Expression in a Mouse Model of Alzheimer's Disease

Jorda, A., Cauli, O., Llabata, J. M. S., Aldasoro, M., Aldasoro, C., Obrador, E., Vila, J. M., Mauricio, M. D., Iradi, A., Guerra‐Ojeda, S., et al. (2019) · International Journal of Biological Sciences · doi:10.7150/ijbs.26703 · Cited by 48 · see citing works

BACE1 Inhibition by Genistein: Biological Evaluation, Kinetic Analysis, and Molecular Docking Simulation

Youn, K., Park, J.-H., Lee, S., Lee, S., Lee, J., Yun, E.-Y., Jeong, W.-S., & Jun, M. (2018) · Journal of Medicinal Food · doi:10.1089/jmf.2017.4068 · Cited by 46 · see citing works

Astrocytes Mediate Protective Actions of Estrogenic Compounds after Traumatic Brain Injury

Martín-Jiménez, C., Gaitán-Vaca, D. M., Mazo, N. A., Echeverrı́a, V., Ashraf, G. M., González, J., Sahebkar, A., García‐Segura, L. M., & Barreto, G. E. (2018) · Neuroendocrinology · doi:10.1159/000495078 · Cited by 44 · see citing works

Flavonoids modulate AMPK/PGC-1α and interconnected pathways toward potential neuroprotective activities

Gravandi, M. M., Fakhri, S., Zarneshan, S. N., Yarmohammadi, A., & Khan, H. Z. (2021) · Metabolic Brain Disease · doi:10.1007/s11011-021-00750-3 · Cited by 45 · see citing works

Genistein, a tool for geroscience

Mas‐Bargues, C., Borrás, C., & Viña, J. (2022) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2022.111665 · Cited by 45 · see citing works

Potential of flavonoids as anti-Alzheimer’s agents: bench to bedside

Kaur, R., Sood, A., Lang, D. K., Bhatia, S., Al‐Harrasi, A., Aleya, L., & Behl, T. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-18165-z · Cited by 44 · see citing works

Anti-amyloidoGenic Effects of Soybean Isoflavones In Vitro: Fluorescence Spectroscopy Demonstrating Direct Binding to Aβ Monomers, Oligomers and Fibrils

Hirohata, M., Ono, K., Takasaki, J.-I., Takahashi, R., Ikeda, T., Morinaga, A., & Yamada, M. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.05.006 · Cited by 43 · see citing works

Genistein inhibits mitochondrial-targeted oxidative damage induced by beta-amyloid peptide 25–35 in PC12 cells

Xi, Y., Yu, H., Ma, W., Ding, B., Ding, J., Yuan, L., Feng, J., & Xiao, R. (2011) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-011-9362-7 · Cited by 42 · see citing works

Isoflavones and PPAR Signaling: A Critical Target in Cardiovascular, Metastatic, and Metabolic Disease

Patel, R. P., & Barnes, S. (2010) · PPAR Research · doi:10.1155/2010/153252 · Cited by 42 · see citing works

Genistein Alleviates β -Amyloid-Induced Inflammatory Damage Through Regulating Toll-Like Receptor 4/Nuclear Factor κ B

Ma, W., Ding, B., Yu, H., Yuan, L., Xi, Y., & Xiao, R. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2014.3150 · Cited by 41 · see citing works

Role of oestrogens on oxidative stress and inflammation in ageing

Viña, J., Gambini, J., García‐García, F. J., Rodríguez‐Mañas, L., & Borrás, C. (2013) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2013-0039 · Cited by 41 · see citing works

The Role of Steroid Hormones in the Modulation of Neuroinflammation by Dietary Interventions

Vasconcelos, A. R., Cabral‐Costa, J. V., Mazucanti, C. H., Scavone, C., & Kawamoto, E. M. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00009 · Cited by 41 · see citing works

Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance

Hou, C., Peng, Y., Qin, C., Fan, F., Liu, J., & Long, J. (2018) · Free Radical Research · doi:10.1080/10715762.2018.1460749 · Cited by 41 · see citing works

Mucopolysaccharidosis type III (Sanfilippo Syndrome): emerging treatment strategies.

de Ruijter, J. D., Valstar, M., & Wijburg, F. (2011) · Current Pharmaceutical Biotechnology · doi:10.2174/138920111795542651 · Cited by 39 · see citing works

Neuroprotective effects of MHY908, a PPAR α/γ dual agonist, in a MPTP-induced Parkinson’s disease model

Lee, Y., Cho, J.-H., Lee, S., Lee, W., Chang, S., Chung, H. Y., Moon, H. R., & Lee, J. (2018) · Brain Research · doi:10.1016/j.brainres.2018.09.036 · Cited by 39 · see citing works

Soy Isoflavones Ameliorate Metabolic and Immunological Alterations of Ovariectomy in Female Wistar Rats: Antioxidant and Estrogen Sparing Potential

Abdelrazek, H. M. A., Mahmoud, M. M. A., Tag, H. M., Greish, S. M., Eltamany, D. A., & Soliman, M. T. A. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/5713606 · Cited by 39 · see citing works

A mechanistic insight of phytoestrogens used for Rheumatoid arthritis: An evidence-based review

Chakraborty, D., Gupta, K., & Biswas, S. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.111039 · Cited by 38 · see citing works

Amyloid Beta1-40-Induced Astrogliosis and the Effect of Genistein Treatment in Rat: A Three-Dimensional Confocal Morphometric and Proteomic Study

Bagheri, M., Rezakhani, A., Nyström, S., Turkina, M. V., Roghani, M., Hammarström, P., & Mohseni, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076526 · Cited by 38 · see citing works

Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells

Calvello, R., Aresta, A. M., Trapani, A., Zambonin, C. G., Cianciulli, A., Salvatore, R., Clodoveo, M. L., Corbo, F., Franchini, C., & Panaro, M. A. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.04.067 · Cited by 38 · see citing works

Pleiotropic Effects of Isoflavones in Inflammation and Chronic Degenerative Diseases

Bernatonienė, J., Kazlauskaitė, J. A., & Kopustinskienė, D. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115656 · Cited by 37 · see citing works

Correction: Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer's disease: Alleviation by pantethine

van Gijsel‐Bonnello, M., Baranger, K., Benech, P. D., Rivera, S., Khrestchatisky, M., Reggi, M. L. D., & Gharib, B. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194586 · Cited by 35 · see citing works

Genistein: mechanisms of action for a pleiotropic neuroprotective agent in stroke

Schreihofer, D. A., & Oppong‐Gyebi, A. (2017) · Nutritional Neuroscience · doi:10.1080/1028415x.2017.1391933 · Cited by 35 · see citing works

Garcinoic acid prevents β-amyloid (Aβ) deposition in the mouse brain

Marinelli, R., Torquato, P., Bartolini, D., Mas‐Bargues, C., Bellezza, G., Gioiello, A., Borrás, C., LUCA, A. D., Fallarino, F., Sebastiani, B., et al. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.013303 · Cited by 35 · see citing works

Genistein induces adipogenic differentiation in human bone marrow mesenchymal stem cells and suppresses their osteogenic potential by upregulating PPARγ

ZHANG, L.-Y., XUE, H.-G., Chen, J., Chai, W., & Ni, M. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3120 · Cited by 35 · see citing works

Effects of Ranolazine on Astrocytes and Neurons in Primary Culture

Aldasoro, M., Guerra‐Ojeda, S., Aguirre-Rueda, D., Mauricio, M. D., Vila, J. M., Marchio, P., Iradi, A., Aldasoro, C., Jorda, A., Obrador, E., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150619 · Cited by 34 · see citing works

The role of soy and soy isoflavones on women’s fertility and related outcomes: An update

Rizzo, G., Feraco, A., Storz, M. A., & Lombardo, M. (2022) · Journal of Nutritional Science · doi:10.1017/jns.2022.15 · Cited by 34 · see citing works

Genistein Attenuates Isoflurane-Induced Neuroinflammation by Inhibiting TLR4-Mediated Microglial-Polarization in vivo and in vitro

Jiang, T., Xu, S., Shen, Y., Xu, Y., & Li, Y. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s304336 · Cited by 34 · see citing works

Repositioning and development of new treatments for neurodegenerative diseases: Focus on neuroinflammation

Arbo, B. D., Schimith, L. E., dos Santos, M. G., & Hort, M. A. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174800 · Cited by 33 · see citing works

Role of Phytoconstituents as PPAR Agonists: Implications for Neurodegenerative Disorders

Sanjay, S., Sharma, A., & Lee, H. (2021) · Biomedicines · doi:10.3390/biomedicines9121914 · Cited by 32 · see citing works

Windows into estradiol effects in Alzheimer's disease therapy.

Mohamd, E. M., Ahmed, H. H., Estefan, S. F., Farrag, A. E.-R. H., & Salah, R. S. (2011) · PubMed · Cited by 29 · see citing works

Mixture effects of dietary flavonoids on steroid hormone synthesis in the human adrenocortical H295R cell line

Ohlsson, Å., Ullerås, E., Nina Cedergreen, G., & Oskarsson, A. (2010) · Food and Chemical Toxicology · doi:10.1016/j.fct.2010.08.021 · Cited by 28 · see citing works

Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats

Lewis, D. K., Johnson, A. B., Stohlgren, S., Harms, A. S., & Sohrabji, F. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.01.006 · Cited by 105 · see citing works

New epidemiologic strategies in Alzheimer's disease may provide clues to prevention and cause

Breitner, J. C. S. (1994) · Neurobiology of Aging · doi:10.1016/0197-4580(94)90199-6 · Cited by 10 · see citing works

Genistein and estradiol increase anti-inflammatory proteins in astrocytes in culture

Pablo, C. (2013) · Journal of Alzheimers Disease & Parkinsonism

PPARγ Agonist Curcumin Reduces the Amyloid-β-Stimulated Inflammatory Responses in Primary Astrocytes

Wang, H., Zhao, Y., Zhang, S., Liu, G.-D., Kang, W., Tang, H., Ding, J., & Chen, S. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-091336 · Cited by 124 · see citing works

Sodium Salicylate and 17β‐Estradiol Attenuate Nuclear Transcription Factor NF‐κB Translocation in Cultured Rat Astroglial Cultures Following Exposure to Amyloid Aβ1‐40 and Lipoplysaccharides

Dodel, R. C., Du, Y., Bales, K. R., Gao, F., & Paul, S. M. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0731453.x · Cited by 114 · see citing works