The association of dietary vitamin C intake with periodontitis among Korean adults: Results from KNHANES Ⅳ
Open accessAbstract
BACKGROUNDS: The association of dietary vitamin C (vit C) on periodontitis requires more valid evidence from large representative samples to enable sufficient adjustments. This study aimed to evaluate the association between dietary vit C intake and periodontitis after controlling for various confounders in the representative Korean adult population. METHOD: A total of 10,930 Korean adults (≥19 years) from the fourth Korean National Health and Nutrition Examination Survey data set were included in this cross-sectional study. Periodontitis was defined as community periodontal index score of 3 or 4. Dietary vit C intake was estimated from a 24-hour dietary record, and categorized into adequate and inadequate according to the Korean Estimated Average Requirement value. Potential confounders included age, sex, income, frequency of tooth brushing, use of floss, dental visit, drinking, smoking, diabetes, hypercholesterolemia, hypertension, and obesity. A multivariable logistic regression analysis and stratified analysis were applied. RESULTS: Those with inadequate dietary vit C intake were more likely by 1.16 times to have periodontitis than those with adequate dietary vit C intake (adjusted odds ratio [aOR] = 1.16, 95% confidence interval = 1.04-1.29). Lowest and middle-low quartile of dietary vit C intake, compared to highest quartile of dietary vit C intake, showed significant association (aOR = 1.28 and 1.22 respectively), which was in a biological-gradient relationship (trend-p <0.05). CONCLUSIONS: Our data showed that inadequate dietary vit C intake was independently associated with periodontitis among Korean adults. Hence, adequate intake of dietary vitamin C could be substantially important on the promotion of periodontal health among Korean adults.
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Several cross-sectional studies indicate low serum vitamin C values and lower vitamin C intake in subjects with periodontitis compared with controls.
“Several cross-sectional studies have indicated low serum vitamin C values and lower vitamin C intake in subjects with periodontitis compared with controls [39,104].”
From A Cross-Talk between Diet and the Oral Microbiome: Balance of Nutrition on Inflammation and Immune System’s Response during Periodontitis (2022) · cites this paper as [104]
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- Authors
- Lee, J.-H., Shin, M.-S., Kim, E.-J., Ahn, Y.-B., & Kim, H.-D.
- Affiliations
- Seoul National University (KR)
- Corresponding author
- Kim, Hyun-Duck
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2017-05-10
- Volume
- 12
- Issue
- 5
- Pages
- e0177074
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC5425026
- OpenAlex
- W2613623169
- Cited by
- 46
- References
- 44
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 7 · 2023: 4 · 2022: 6 · 2021: 3 · 2020: 7 · 2019: 6 · 2018: 3 · 2016: 1
- FWCI
- 6.04
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- National Research Foundation of Korea (KR) (No. 2015-048003)
- Topics
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
- Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
- Keywords
- vitamin C intake, periodontitis, Korean adults, periodontal health, confounding adjustment, Korea National Health and Nutrition Examination Survey
- MeSH terms
- Adult, Aged, Alcohol Drinking, Ascorbic Acid, Cross-Sectional Studies, Diabetes Mellitus, Female, Humans, Income, Male, Middle Aged, Nutrition Surveys, Obesity, Periodontal Index, Periodontitis, Smoking, Toothbrushing, Vitamins, Odds Ratio, Young Adult, Republic of Korea
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