The Pathobiochemistry of Nitrogen Dioxide
Abstract
Nitrogen dioxide (*NO2) is an oxidizing free radical which can initiate a variety of destructive pathways in living systems, and several diseases are suspected to be connected with both exogenously and endogenously formed *NO2. Peroxynitrite (ONOO-/ONOOH) is believed to be an important endogenous source of *NO2 radicals, but other sources, among them enzymatically ones, have been identified recently. It also became clear during the last few years that in vivo formation of 3-nitrotyrosine strictly depends on the availability of *NO2 radicals. Since nitrogen dioxide is a very toxic compound an arsenal of antioxidants (e.g. vitamin C, glutathione, vitamin E, and beta-carotene) must eliminate this harmful radical in vivo. Here the recently identified superoxide (O2*-)-dependent formation of peroxynitrate (O2NOO-) and the central role of vitamin C are of special importance.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Nitrogen dioxide (NO2·) is formed in the reaction of NO with oxygen.
“Nitrogen dioxide (NO2·) is formed in the reaction of NO with oxygen (Eq. 28) (509, 1018).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [509]
Cites
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704 · see citing works
p53 Mutations in Human Cancers
Hollstein, M., Sidransky, D., Vogelstein, B., & Harris, C. C. (1991) · Science · doi:10.1126/science.1905840 · Cited by 8,018 · see citing works
Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029 · see citing works
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.
Ignarro, L. J., Buga, G. M., Wood, K. S., Byrns, R. E., & Chaudhuri, G. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9265 · Cited by 5,074 · see citing works
(1994) · New England Journal of Medicine · doi:10.1056/nejm199404143301501 · Cited by 4,737 · see citing works
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite
Hibbs, J. B., Taintor, R. R., & Vavrin, Z. (1987) · Science · doi:10.1126/science.2432665 · Cited by 1,527 · see citing works
Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
Eiserich, J. P., Hristova, M., Cross, C. E., Jones, A. D., Freeman, B. A., Halliwell, B., & van der Vliet, A. (1998) · Nature · doi:10.1038/34923 · Cited by 1,496 · see citing works
Direct observation of a free radical interaction between vitamin E and vitamin C
Packer, J. E., Slater, T. F., & WILLSON, R. L. (1979) · Nature · doi:10.1038/278737a0 · Cited by 1,473 · see citing works
DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its Progenitors
Wink, D. A., Kasprzak, K. S., Maragos, C. M., Elespuru, R. K., Misra, M., Dunams, T. M., Cebula, T. A., Koch, W. H., Andrews, A. W., Allen, J. S., et al. (1991) · Science · doi:10.1126/science.1948068 · Cited by 1,235 · see citing works
Extensive Nitration of Protein Tyrosines in Human Atherosclerosis Detected by Immunohistochemistry
Beckman, J. S., Ye, Y. Z., Anderson, P. G., Chen, J., Accavitti, M. A., Tarpey, M. M., & White, C. R. (1994) · Biological Chemistry Hoppe-Seyler · doi:10.1515/bchm3.1994.375.2.81 · Cited by 1,122 · see citing works
Oxidative Damage and Tyrosine Nitration from Peroxynitrite
Beckman, J. S. (1996) · Chemical Research in Toxicology · doi:10.1021/tx9501445 · Cited by 993 · see citing works
DNA damage and mutation in human cells exposed to nitric oxide in vitro.
Nguyen, T., Brunson, D. C., Crespi, C. L., Penman, B. W., Wishnok, J. S., & Tannenbaum, S. R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.7.3030 · Cited by 972 · see citing works
Ignarro, L. J., Fukuto, J. M., Griscavage, J. M., Rogers, N. E., & Byrns, R. E. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.8103 · Cited by 856 · see citing works
Oxidation of nitrogen-oxides by bound dioxygen in hemoproteins
Doyle, M. P., & Hoekstra, J. W. (1981) · Journal of Inorganic Biochemistry · doi:10.1016/s0162-0134(00)80291-3 · Cited by 643 · see citing works
Kissner, R., Nauser, T., Bugnon, P., Lye, P. G., & Koppenol, W. H. (1997) · Chemical Research in Toxicology · doi:10.1021/tx970160x · Cited by 629 · see citing works
Malinski, T., Bailey, F., Zhang, Z. G., & Chopp, M. (1993) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1993.48 · Cited by 625 · see citing works
Liu, X., Miller, M. J. S., Joshi, M. S., Thomas, D. D., & Lancaster, J. R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.5.2175 · Cited by 602 · see citing works
Haddad, I. Y., Pataki, G., Yu, Y., GALLIANI, C. A., Beckman, J. S., & Matalon, S. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117607 · Cited by 594 · see citing works
Mirvish, S. S., Wallcave, L., Eagen, M., & Shubik, P. (1972) · Science · doi:10.1126/science.177.4043.65 · Cited by 496 · see citing works
Crow, J. P., Sampson, J. B., Zhuang, Y., Thompson, J. A., & Beckman, J. S. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69051936.x · Cited by 487 · see citing works
Status of the mitochondrial pool of glutathione in the isolated hepatocyte.
Meredith, M. J., & Reed, D. J. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34844-0 · Cited by 446 · see citing works
Saleh, D. M., Ernst, P., Lim, S., Barnes, P. J., & Giaid, A. (1998) · The FASEB Journal · doi:10.1096/fasebj.12.11.929 · Cited by 437 · see citing works
Fürstner, A., Ackermann, L., Gabor, B., Goddard, R., Lehmann, C. W., MYNOTT, R. J., Stelzer, F., & Thiel, O. R. (2001) · Chemistry - A European Journal · doi:10.1002/1521-3765(20010803)7:15 · Cited by 423 · see citing works
Diffusion of Nitric Oxide in the Aorta Wall Monitored in Situ by Porphyrinic Microsensors
Malinski, T., Taha, Z., Grunfeld, S., Patton, S. R., Kapturczak, M., & Tomboulian, P. (1993) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1993.1735 · Cited by 417 · see citing works
Superoxide Reacts with Nitric Oxide to Nitrate Tyrosine at Physiological pH via Peroxynitrite
Reiter, C. D., Teng, R., & Beckman, J. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m910433199 · Cited by 385 · see citing works
Wink, D. A., Nims, R. W., Darbyshire, J. F., Christodoulou, D., Hanbauer, I., Cox, G. W., Laval, F., Laval, J., & Cook, J. A. (1994) · Chemical Research in Toxicology · doi:10.1021/tx00040a007 · Cited by 378 · see citing works
Ohshima, H., & Bartsch, H. (1981) · PubMed · Cited by 344 · see citing works
Gamma-tocopherol detoxification of nitrogen dioxide: superiority to alpha-tocopherol
Cooney, R. V., Franke, A. A., Harwood, P. J., Hatch-Pigott, V, Custer, L. J., & Mordan, L. J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.5.1771 · Cited by 343 · see citing works
The basic chemistry of nitrogen monoxide and peroxynitrite
Koppenol, W. H. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00093-8 · Cited by 338 · see citing works
NAD(P)H, a directly operating antioxidant?
Kirsch, M., & de GROOT, H. (2001) · The FASEB Journal · doi:10.1096/fj.00-0823hyp · Cited by 331 · see citing works
Self-citationNitrates, nitrites and gastric cancer in Great Britain
Forman, D., Al-Dabbagh, S. A., & Doll, R. (1985) · Nature · doi:10.1038/313620a0 · Cited by 310 · see citing works
Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction
Eiserich, J. P., van der Vliet, A., Handelman, G., Halliwell, B. B., & Cross, C. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.6.1490s · Cited by 306 · see citing works
Direct EPR Detection of the Carbonate Radical Anion Produced from Peroxynitrite and Carbon Dioxide
Bonini, M. G., Radi, R., Ferrer-Sueta, G., Ferreira, A. M. D. C., & Augusto, O. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.16.10802 · Cited by 293 · see citing works
Antioxidation mechanisms of uric acid
Simic, M. G., & Jovanović, S. V. (1989) · Journal of the American Chemical Society · doi:10.1021/ja00197a042 · Cited by 290 · see citing works
Comparative mechanisms and rates of free radical scavenging by carotenoid antioxidants
Mortensen, A., Skibsted, L. H., Sampson, J., Rice-Evans, C. A., & Everett, S. A. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)01355-0 · Cited by 290 · see citing works
Formation of singlet oxygen by the myeloperoxidase-mediated antimicrobial system.
Rosen, H., & Klebanoff, S. J. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40127-x · Cited by 263 · see citing works
Pathways of peroxynitrite oxidation of thiol groups
Quijano, C., Álvarez, B., Gatti, R. M., Augusto, O., & Radí, R. (1997) · Biochemical Journal · doi:10.1042/bj3220167 · Cited by 262 · see citing works
Pryor, W. A., & Lightsey, J. W. (1981) · Science · doi:10.1126/science.214.4519.435 · Cited by 255 · see citing works
Lipoperoxidation of Lung Lipids in Rats Exposed to Nitrogen Dioxide
Thomas, H. V., Mueller, P. K., & Lyman, R. L. (1968) · Science · doi:10.1126/science.159.3814.532 · Cited by 252 · see citing works
Goldstein, S., & Czapski, G. (1995) · Journal of the American Chemical Society · doi:10.1021/ja00154a007 · Cited by 250 · see citing works
Absorption spectra and reaction kinetics of NO2, N2O3, and N2O4 in aqueous solution
Treinin, A., & Hayon, E. (1970) · Journal of the American Chemical Society · doi:10.1021/ja00723a001 · Cited by 217 · see citing works
Formation and decay of peroxynitric acid: a pulse radiolysis study
Loegager, T., & Sehested, K. (1993) · The Journal of Physical Chemistry · doi:10.1021/j100141a025 · Cited by 211 · see citing works
Goldstein, S., & Czapski, G. (1996) · Journal of the American Chemical Society · doi:10.1021/ja9536680 · Cited by 205 · see citing works
Everett, S. A., Dennis, M. F., Patel, K. B., Maddix, S. P., Kundu, S. C., & WILLSON, R. L. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.8.3988 · Cited by 201 · see citing works
Bonini, M. G., & Augusto, O. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008456200 · Cited by 191 · see citing works
Nitric Oxide-induced Deamination of Cytosine and Guanine in Deoxynucleosides and Oligonucleotides
Caulfield, J. L., Wishnok, J. S., & Tannenbaum, S. R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.21.12689 · Cited by 186 · see citing works
Local nitric oxide production in viral and autoimmune diseases of the central nervous system.
Hooper, D. C., Ohnishi, S. T., Kean, R. B., Numagami, Y., Dietzschold, B., & Koprowski, H. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.12.5312 · Cited by 184 · see citing works
Tyrosine Nitration by Simultaneous Generation of ⋅NO and O⨪2 under Physiological Conditions
Goldstein, S., Czapski, G., Lind, J., & Merényi, G. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.5.3031 · Cited by 177 · see citing works
Pulsradiolytische Untersuchung einiger Elementarprozesse der Oxydation und Reduktion des Nitritions
Grätzel, M., Henglein, A., Lilie, J., & Beck, G. (1969) · Berichte der Bunsengesellschaft für physikalische Chemie · doi:10.1002/bbpc.19690730707 · Cited by 166 · see citing works
Neuroprotection by S ‐nitrosoglutathione of brain dopamine neurons from oxidative stress
Rauhala, P. V., Lin, A. M., & Chiueh, C. C. (1998) · The FASEB Journal · doi:10.1096/fasebj.12.2.165 · Cited by 166 · see citing works
Light-Mediated Conversion of Nitrogen Dioxide to Nitric Oxide by Carotenoids
Cooney, R. V., Harwood, P. J., Custer, L. J., & Franke, A. A. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102460 · Cited by 165 · see citing works
Protein Tyrosine Nitration in Cytokine-activated Murine Macrophages
Pfeiffer, S., Lass, A., Schmidt, K., & Mayer, B. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100585200 · Cited by 160 · see citing works
Nitric oxide rapidly scavenges tyrosine and tryptophan radicals
Eiserich, J. P., Butler, J., van der Vliet, A., Cross, C. E., & Halliwell, B. B. (1995) · Biochemical Journal · doi:10.1042/bj3100745 · Cited by 151 · see citing works
β‐Carotene with vitamins E and C offers synergistic cell protection against NOx
Böhm, F., Edge, R., McGarvey, D. J., & Truscott, T. G. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)01173-9 · Cited by 150 · see citing works
Pryor, W. A., Lightsey, J. W., & Church, D. F. (1982) · Journal of the American Chemical Society · doi:10.1021/ja00388a035 · Cited by 149 · see citing works
An autocatalytic mechanism of protein nitrosylation
Nedospasov, A., Rafikov, R., Beda, N., & Nudler, E. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.250398197 · Cited by 144 · see citing works
Goldstein, S., & Czapski, G. (1998) · Journal of the American Chemical Society · doi:10.1021/ja9733043 · Cited by 143 · see citing works
CO2-Catalyzed One-Electron Oxidations by Peroxynitrite: Properties of the Reactive Intermediate
Lymar, S. V., & Hurst, J. K. (1998) · Inorganic Chemistry · doi:10.1021/ic970946i · Cited by 141 · see citing works
Distinction between Nitrosating Mechanisms within Human Cells and Aqueous Solution
Espey, M. G., Miranda, K. M., Thomas, D. D., & Wink, D. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101723200 · Cited by 141 · see citing works
The Reactivity And Structure Of Nitrogen Dioxide
Gray, P., & Yoffe, A. D. (1955) · Chemical Reviews · doi:10.1021/cr50006a001 · Cited by 140 · see citing works
Interaction of nitrogen dioxide with human plasma Antioxidant depletion and oxidative damage
Halliwell, B. B., Hu, M., Louie, S., Duvall, T. R., Tarkington, B. K., Motchnik, P. A., & Cross, C. E. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)81185-o · Cited by 139 · see citing works
Hodges, G. R., & Ingold, K. U. (1999) · Journal of the American Chemical Society · doi:10.1021/ja991077u · Cited by 131 · see citing works
A Paramagnetic Species in Irradiated NaNO2
Zeldes, H., & Livingston, R. (1961) · The Journal of Chemical Physics · doi:10.1063/1.1731969 · Cited by 112 · see citing works
Role of the Carbonate Radical Anion in Tyrosine Nitration and Hydroxylation by Peroxynitrite
Santos, C. X. C., Bonini, M. G., & Augusto, O. (2000) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2000.1751 · Cited by 104 · see citing works
Mechanism and Thermochemistry of Peroxynitrite Decomposition in Water
Merényi, G., Lind, J., Goldstein, S., & Czapski, G. (1999) · The Journal of Physical Chemistry A · doi:10.1021/jp984686h · Cited by 104 · see citing works
The Yield of Hydroxyl Radical from the Decomposition of Peroxynitrous Acid
Gerasimov, O. V., & Lymar, S. V. (1999) · Inorganic Chemistry · doi:10.1021/ic990384y · Cited by 101 · see citing works
Masuda, M., Mower, H. F., Pignatelli, B., Celan, I., Friesen, M. D., Nishino, H., & Ohshima, H. (2000) · Chemical Research in Toxicology · doi:10.1021/tx990120o · Cited by 101 · see citing works
Toxicity of nitrogen dioxide: an introduction
Elsayed, N. M. (1994) · Toxicology · doi:10.1016/0300-483x(94)90096-5 · Cited by 95 · see citing works
Ascorbate Is a Potent Antioxidant against Peroxynitrite-induced Oxidation Reactions
Kirsch, M., & de GROOT, H. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909228199 · Cited by 88 · see citing works
Self-citationThe Fate of the Oxidizing Tyrosyl Radical in the Presence of Glutathione and Ascorbate
Sturgeon, B. E., Sipe, H. J., Barr, D. P., Corbett, J. T., Martinez, J. G., & Mason, R. P. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.46.30116 · Cited by 86 · see citing works
Ab Initio Study of the N2O4 Potential Energy Surface. Computational Evidence for a New N2O4 Isomer
McKee, M. L. (1995) · Journal of the American Chemical Society · doi:10.1021/ja00110a020 · Cited by 86 · see citing works
Hydrolysis equilibrium of dinitrogen trioxide in dilute acid solution
Markovits, G. Y., Schwartz, S. E., & Newman, L. (1981) · Inorganic Chemistry · doi:10.1021/ic50216a025 · Cited by 84 · see citing works
Cueto, R., & Pryor, W. A. (1994) · Vibrational Spectroscopy · doi:10.1016/0924-2031(94)85045-3 · Cited by 81 · see citing works
Product analysis of the hydroxyl + nitrogen dioxide + M reaction
Burkholder, J. B., Hammer, P. D., & Howard, C. J. (1987) · The Journal of Physical Chemistry · doi:10.1021/j100292a032 · Cited by 76 · see citing works
van der Leede, B. M., Brink, C. E. V. D., Pijnappel, W. W. M. P., Sonneveld, E., van der Saag, P. T., & van der Burg, B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.29.17921 · Cited by 75 · see citing works
Decomposition of pernitric acid in aqueous solution
Lammel, G., Perner, D., & Warneck, P. (1990) · The Journal of Physical Chemistry · doi:10.1021/j100378a091 · Cited by 74 · see citing works
Direct Observation of Intermediates in the Reaction of Peroxynitrite with Carbon Dioxide
Meli, R., Nauser, T., & Koppenol, W. H. (1999) · Helvetica Chimica Acta · doi:10.1002/(sici)1522-2675(19990505)82:5 · Cited by 72 · see citing works
Eiserich, J. P., Vossen, V., O’neill, C. A., Halliwell, B. B., Cross, C. E., & van der Vliet, A. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)01011-0 · Cited by 71 · see citing works
Singh, R. J., Goss, S. P. A., Joseph, J., & Kalyanaraman, B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.12912 · Cited by 71 · see citing works
Amounts of Oxides of Nitrogen and Carbon Monoxide in Cigarette Smoke, with and without Inhalation
BOKHOVEN, C., & Niessen, H. (1961) · Nature · doi:10.1038/192458a0 · Cited by 70 · see citing works
Lehnig, M. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1268 · Cited by 65 · see citing works
β‐Carotene effectively scavenges toxic nitrogen oxides: nitrogen dioxide and peroxynitrous acid
Kikugawa, K., Hiramoto, K., Tomiyama, S., & Asano, Y. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)00124-5 · Cited by 63 · see citing works
Aqueous Peroxynitric Acid (HOONO2): A Novel Synthesis and Some Chemical and Spectroscopic Properties
Appelman, E. H., & Gosztola, D. J. (1995) · Inorganic Chemistry · doi:10.1021/ic00108a007 · Cited by 58 · see citing works
Review of the genotoxicity of nitrogen oxides
Victorin, K. (1994) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(94)90011-6 · Cited by 56 · see citing works
Zhang, Z., Side, Y., Weizhen, L., Wenfeng, W., Yizun, J., & Nianyun, L. (1998) · Free Radical Research · doi:10.1080/10715769800300021 · Cited by 48 · see citing works
Nitration and Nitrosation by Peroxynitrite: Role of CO2 and Evidence for Common Intermediates
Uppu, R. M., Squadrito, G. L., Bolzan, R. M., & Pryor, W. A. (2000) · Journal of the American Chemical Society · doi:10.1021/ja000270h · Cited by 48 · see citing works
NO2-induced DNA single strand breaks are inhibited by antioxidative vitamins in V79 cells
Bittrich, H., Mátzig, A. K., Kráker, I., & Appel, K. E. (1993) · Chemico-Biological Interactions · doi:10.1016/0009-2797(93)90098-j · Cited by 46 · see citing works
Determination of selectivity of reactive nitrogen oxide species for various substrates
Wink, D. A., Grisham, M. B., Miles, A. M., Nims, R. W., Krishna, M. C., Pacelli, R., Teague, D., Poore, C. M. B., Cook, J. A., & Ford, P. C. (1996) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(96)68014-8 · Cited by 44 · see citing works
Microperoxidase 8 catalyzed nitration of phenol by nitrogen dioxide radicals
Ricoux, R., Boucher, J., Mansuy, D., & Mahy, J. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2001.02288.x · Cited by 43 · see citing works
Reactivity of Peroxynitric Acid (O2NOOH): A Pulse Radiolysis Study
Goldstein, S., & Czapski, G. (1997) · Inorganic Chemistry · doi:10.1021/ic961186z · Cited by 42 · see citing works
Meyer, D. J., Kramer, H., & KETTERER, B. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)00904-x · Cited by 35 · see citing works
Nitrosating Agents: Is Peroxynitrite a Likely Candidate?
Williams, D. L. H. (1997) · Nitric Oxide · doi:10.1006/niox.1997.0159 · Cited by 34 · see citing works
Cytotoxicity of NO2 gas to cultured human and murine cells in an inverted monolayer exposure system
Tu, B., Wallin, A., Moldéus, P., & Cotgreave, I. A. (1995) · Toxicology · doi:10.1016/0300-483x(94)02909-e · Cited by 31 · see citing works
Does β-Carotene Protect Membrane Lipids from Nitrogen Dioxide?
Khopde, S. M., Priyadarsini, K. I., Mukherjee, T., Kulkarni, P. B., Satav, J. G., & Bhattacharya, R. K. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00046-x · Cited by 28 · see citing works
Atmospheric mutagens I. Sulfur oxides and nitrogen oxides
Fishbein, L. (1976) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(76)90004-x · Cited by 27 · see citing works
Tu, B. (1995) · Toxicology · doi:10.1016/0300-483x(94)02977-3 · Cited by 23 · see citing works
Nitric oxide in cigarette smoke as a mediator of oxidative damage
Epperlein, M. M., Nourooz‐Zadeh, J., Noronha-Dutra, A. A., & Woolf, N. (1996) · International Journal of Experimental Pathology · doi:10.1046/j.1365-2613.1996.9930331.x · Cited by 22 · see citing works
Public Health: 'Natural' Cancer Prevention Trial Halted
Peterson, K. (1996) · Science · doi:10.1126/science.271.5248.441b · Cited by 22 · see citing works
The kinetics and mechanism of the aminolysis of phenethyl nitrite
Ōae, S., Asai, N., & Fujimori, K. (1978) · Journal of the Chemical Society Perkin Transactions 2 · doi:10.1039/p29780001124 · Cited by 21 · see citing works
Lehnig, M. (2001) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2001.2494 · Cited by 16 · see citing works
Light-Mediated Conversion of Nitrogen Dioxide to Nitric Oxide by Carotenoids
Cooney, R. V., Harwood, P. J., Custer, L. J., et al. (1994) · Environmental Health Perspectives · doi:10.2307/3432041 · Cited by 16 · see citing works
Chemistry and biology of nitrosated peptides.
Bc, C. (1989) · PubMed · Cited by 15 · see citing works
The kinetics of the reaction between NO and O2 as studied by a novel approach
Caccia, S., Denisov, I. G., & Perrella, M. (1999) · Biophysical Chemistry · doi:10.1016/s0301-4622(98)00219-1 · Cited by 14 · see citing works
Lehnig, M., & Jakobi, K. (2000) · Journal of the Chemical Society Perkin Transactions 2 · doi:10.1039/b005049k · Cited by 13 · see citing works
Ascorbate availability and neurodegeneration in amyotrophic lateral sclerosis
Kok, A. (1997) · Medical Hypotheses · doi:10.1016/s0306-9877(97)90097-9 · Cited by 12 · see citing works
Akerboom, T. P. M., Ji, Y., Wagner, G., & Sies, H. (1997) · Biochemical Pharmacology · doi:10.1016/s0006-2952(96)00602-8 · Cited by 11 · see citing works
Butler, A. R., Rutherford, T. J., Short, D. M., & Ridd, J. H. (2000) · Nitric Oxide · doi:10.1006/niox.2000.0299 · Cited by 9 · see citing works
Schürmann, K., & Lehnig, M. (2000) · Applied Magnetic Resonance · doi:10.1007/bf03162151 · Cited by 9 · see citing works
Radical Dinitroalkane Dianions from the Nitration of Nitroalkanes by Peroxynitrite
Arnold, E. V., Bohle, D. S., & Hu, Y. (2000) · Chemical Research in Toxicology · doi:10.1021/tx0001474 · Cited by 5 · see citing works
Sauerbeck, G., Parkin, C. S., Houston, S., Whall, C., Newton, A. J., & Carlyle, J. (2000) · The Journal of the Royal Society for the Promotion of Health · doi:10.1177/146642400012000308 · Cited by 4 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Role of Oxidative Modifications in Atherosclerosis
Stocker, R., & Keaney, J. F. (2004) · Physiological Reviews · doi:10.1152/physrev.00047.2003 · Cited by 2,611 · see citing works
Synthetic Expanded Porphyrin Chemistry
Sessler, J. L., & Seidel, D. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200561 · Cited by 927 · see citing works
Biochemistry of Peroxynitrite and Protein Tyrosine Nitration
Ferrer‐Sueta, G., Campolo, N., Trujillo, M., Bartesaghi, S., Carballal, S., Romero, N., Álvarez, B., & Radí, R. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00568 · Cited by 645 · see citing works
Mikkelsen, R. B., & Wardman, P. (2003) · Oncogene · doi:10.1038/sj.onc.1206663 · Cited by 591 · see citing works
Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications
Davies, M. J., Hawkins, C. L., Pattison, D. I., & Rees, M. D. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1927 · Cited by 556 · see citing works
Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation
Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews · doi:10.1152/physrev.00036.2017 · Cited by 541 · see citing works
Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease
van der Veen, B. S., de Winther, M. P. J., & Heeringa, P. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2538 · Cited by 522 · see citing works
Oxygen and reactive oxygen species in cartilage degradation: friends or foes?
Henrotin, Y. E., Kurz, B., & Aigner, T. G. (2005) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2005.04.002 · Cited by 487 · see citing works
Synthesechemie expandierter Porphyrine
Sessler, J. L., & Seidel, D. (2003) · Angewandte Chemie · doi:10.1002/ange.200200561 · Cited by 306 · see citing works
The Reaction between Nitrite and Deoxyhemoglobin
Huang, K. T., Keszler, A., Patel, N., Patel, R. P., Gladwin, M. T., Kim-Shapiro, D. B., & Hogg, N. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501496200 · Cited by 253 · see citing works
Lüth, H., Münch, G., & Arendt, T. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03280-8 · Cited by 233 · see citing works
Associations between Short-Term Changes in Nitrogen Dioxide and Mortality in Canadian Cities
Burnett, R. T., Stieb, D. M., Brook, J. R., Cakmak, S., Dales, R., Raizenne, M. E., Vincent, R., & Dann, T. F. (2004) · Archives of Environmental Health An International Journal · doi:10.3200/aeoh.59.5.228-236 · Cited by 201 · see citing works
Wrona, M., Patel, K., & Wardman, P. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.10.022 · Cited by 195 · see citing works
Opländer, C., Volkmar, C. M., Paunel‐Görgülü, A., van Faassen, E. E., Heiß, C., Kelm, M., Halmer, D., Mürtz, M., Pallua, N., & Suschek, C. V. (2009) · Circulation Research · doi:10.1161/circresaha.109.207019 · Cited by 172 · see citing works
Cardiovascular Drugs and Serum Uric Acid
Reyes, A. J. (2003) · Cardiovascular Drugs and Therapy · doi:10.1023/b:card.0000015855.02485.e3 · Cited by 163 · see citing works
Emerging Supramolecular Chemistry of Gases
Rudkevich, D. M. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200300606 · Cited by 160 · see citing works
Peri, L., Pietraforte, D., Scorza, G., Napolitano, A., Fogliano, V., & Minetti, M. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.04.021 · Cited by 154 · see citing works
Aging Theories of Primary Osteoarthritis: From Epidemiology to Molecular Biology
Aigner, T. G., Rose, J., Martin, J. A., & Buckwalter, J. A. (2004) · Rejuvenation Research · doi:10.1089/1549168041552964 · Cited by 142 · see citing works
Redox Mechanisms in Neurodegeneration: From Disease Outcomes to Therapeutic Opportunities
Sbodio, J. I., Snyder, S. H., & Paul, B. D. (2018) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7321 · Cited by 143 · see citing works
The Reaction between Nitrite and Oxyhemoglobin
Keszler, A., Piknova, B., Schechter, A. N., & Hogg, N. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m705630200 · Cited by 121 · see citing works
Nitric oxide and its derivatives in the cancer battlefield
Kamm, A., Przychodzen, P., Kuban-Jankowska, A., Jacewicz, D., Dabrowska, A. M., Nussberger, S., Wozniak, M., & Gorska-Ponikowska, M. (2019) · Nitric Oxide · doi:10.1016/j.niox.2019.09.005 · Cited by 120 · see citing works
Nitric oxide synthase and intermittent hypoxia-induced spatial learning deficits in the rat
Li, R. C., Row, B. W., Kheirandish, L., Brittian, K. R., Gozal, E., Guo, S. Z., Sachleben, L. R., & Gozal, D. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2004.05.006 · Cited by 119 · see citing works
Paunel, A. N., Dejam, A., Thelen, S., Kirsch, M., Horstjann, M., Gharini, P., Mürtz, M., Kelm, M., de Groot, H., Kolb-Bachofen, V., et al. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.11.018 · Cited by 115 · see citing works
Self-citationOxidative Damage Precedes Nitrative Damage in Adriamycin-Induced Cardiac Mitochondrial Injury
Chaiswing, L., Cole, M. P., Clair, D. K. S., Ittarat, W., Szweda, L. I., & Oberley, T. D. (2004) · Toxicologic Pathology · doi:10.1080/01926230490502601 · Cited by 108 · see citing works
Quijano, C., Romero, N., & Radí, R. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.04.014 · Cited by 102 · see citing works
The solution chemistry of nitric oxide and other reactive nitrogen species
Ford, P. C., & Miranda, K. M. (2020) · Nitric Oxide · doi:10.1016/j.niox.2020.07.004 · Cited by 100 · see citing works
Kermorvant‐Duchemin, E., Sennlaub, F., Sirinyan, M., Brault, S., Andelfinger, G., Kooli, A., Germain, S., Ong, H., D’Orléans-Juste, P., Gobeil, F., et al. (2005) · Nature Medicine · doi:10.1038/nm1336 · Cited by 95 · see citing works
The Autoxidation of Tetrahydrobiopterin Revisited
Kirsch, M., Korth, H., Stenert, V., Sustmann, R., & de GROOT, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211779200 · Cited by 91 · see citing works
Self-citationThomas, D. D., Miranda, K. M., Colton, C. A., Citrin, D., Espey, M. G., & Wink, D. A. (2003) · Antioxidants & Redox Signaling · doi:10.1089/152308603322110887 · Cited by 89 · see citing works
The built environment as determinant of childhood obesity: A systematic literature review
Malacarne, D. F., Handakas, E., Robinson, O., Pineda, E., Sáez, M., Chatzi, L., & Fecht, D. (2021) · Obesity Reviews · doi:10.1111/obr.13385 · Cited by 88 · see citing works
Liebmann, J., Scherer, J., Bibinov, N. K., Rajasekaran, P., Kovacs, R., Gesche, R., Awakowicz, P., & Kolb-Bachofen, V. (2010) · Nitric Oxide · doi:10.1016/j.niox.2010.09.005 · Cited by 83 · see citing works
Sensing and Fixation of NO2/N2O4by Calix[4]Arenes
Zyryanov, G. V., Kang, Y., & Rudkevich, D. M. (2003) · Journal of the American Chemical Society · doi:10.1021/ja029166l · Cited by 79 · see citing works
Kirsch, M., Korth, H., Wensing, A., Sustmann, R., & de GROOT, H. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2003.07.002 · Cited by 76 · see citing works
Self-citationYan, Y., Krishnakumar, S., Yu, H., Ramishetti, S., Deng, L., Wang, S., Huang, L., & Huang, D. (2013) · Journal of the American Chemical Society · doi:10.1021/ja401555y · Cited by 74 · see citing works
Understanding ischemic retinopathies: emerging concepts from oxygen-induced retinopathy
Kermorvant‐Duchemin, E., Sapieha, P. S., Sirinyan, M., Beauchamp, M., Checchin, D., Hardy, P., Sennlaub, F., Lachapelle, P., & Chemtob, S. (2009) · Documenta Ophthalmologica · doi:10.1007/s10633-009-9201-x · Cited by 73 · see citing works
Zeng, T., Deng, G., Zhong, W., Gao, Z., Ma, S., Mo, C., Li, Y., Huang, S., Zhou, C., Lai, Y., et al. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.01.009 · Cited by 71 · see citing works
Nitrite, a naturally occurring precursor of nitric oxide that acts like a ‘prodrug’
Suschek, C. V., SCHEWE, T., Sies, H., & Kröncke, K. (2006) · Biological Chemistry · doi:10.1515/bc.2006.065 · Cited by 72 · see citing works
Biochemical Markers and Risk Factors of Alzheimers Disease
Flirski, M., & Sobów, T. (2005) · Current Alzheimer Research · doi:10.2174/1567205052772704 · Cited by 67 · see citing works
Chaiswing, L., Cole, M. P., Ittarat, W., Szweda, L. I., Clair, D. K. S., & Oberley, T. D. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-04-0322 · Cited by 67 · see citing works
Suschek, C. V., & Opländer, C. (2016) · Clinical Plasma Medicine · doi:10.1016/j.cpme.2016.05.001 · Cited by 63 · see citing works
Multi-radical (ORAC MR5 ) antioxidant capacity of selected berries and effects of food processing
Prior, R. L., Sintara, M., & Chang, T. (2016) · Journal of Berry Research · doi:10.3233/jbr-160127 · Cited by 61 · see citing works
Kennett, E. C., & Davies, M. J. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.05.002 · Cited by 59 · see citing works
Groneberg‐Kloft, B., Kraus, T., van Mark, A., Wagner, U., & Fischer, A. (2006) · Journal of Occupational Medicine and Toxicology · doi:10.1186/1745-6673-1-6 · Cited by 58 · see citing works
Kytzia, A., Korth, H., Sustmann, R., de GROOT, H., & Kirsch, M. (2006) · Chemistry - A European Journal · doi:10.1002/chem.200600405 · Cited by 57 · see citing works
Self-citationToward Synthetic Tubes for NO2/N2O4: Design, Synthesis, and Host−Guest Chemistry
Zyryanov, G. V., & Rudkevich, D. M. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0392869 · Cited by 54 · see citing works
Huang, J. V., Leung, G. M., & Schooling, C. M. (2018) · International Journal of Obesity · doi:10.1038/s41366-018-0070-9 · Cited by 48 · see citing works
The role of chronic inflammation in cardiovascular disease and its regulation by nutrients.
Osiecki, H. (2004) · PubMed · Cited by 47 · see citing works
Non-enzymatic NO production in human skin: Effect of UVA on cutaneous NO stores
Suschek, C. V., Opländer, C., & van Faassen, E. E. (2009) · Nitric Oxide · doi:10.1016/j.niox.2009.10.006 · Cited by 44 · see citing works
Shaw, S., & Heyst, B. V. (2022) · Atmosphere · doi:10.3390/atmos13060967 · Cited by 44 · see citing works
Beckers, H., Zeng, X., & Willner, H. (2009) · Chemistry - A European Journal · doi:10.1002/chem.200902406 · Cited by 44 · see citing works
Nitration of γ-tocopherol in plant tissues
Desel, C., Hubbermann, E. M., Schwarz, K., & Krupinska, K. (2007) · Planta · doi:10.1007/s00425-007-0552-9 · Cited by 43 · see citing works
Kurtikyan, T. S., & Ford, P. C. (2007) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2007.10.012 · Cited by 41 · see citing works
Opländer, C., & Suschek, C. V. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms14010191 · Cited by 41 · see citing works
Supramolekulare Chemie von Gasen
Rudkevich, D. M. (2004) · Angewandte Chemie · doi:10.1002/ange.200300606 · Cited by 40 · see citing works
Aging, lipid modifications and phospholipases—new concepts
Balazy, M., & Nigam, S. (2003) · Ageing Research Reviews · doi:10.1016/s1568-1637(02)00065-x · Cited by 39 · see citing works
Kurtikyan, T. S., & Ford, P. C. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200502409 · Cited by 39 · see citing works
Kurtikyan, T. S., Hovhannisyan, A. A., Hakobyan, M. E., Patterson, J. C., Iretskii, A. V., & Ford, P. C. (2007) · Journal of the American Chemical Society · doi:10.1021/ja067245h · Cited by 36 · see citing works
Encapsulated Reagents for Nitrosation
Zyryanov, G. V., & Rudkevich, D. M. (2003) · Organic Letters · doi:10.1021/ol0342195 · Cited by 36 · see citing works
Badrakhan, C.-D., Petrat, F., Holzhauser, M., Fuchs, A., Lomonosova, E. E., de GROOT, H., & Kirsch, M. (2004) · Journal of Biochemical and Biophysical Methods · doi:10.1016/j.jbbm.2003.10.010 · Cited by 35 · see citing works
Self-citationGao, L., Chen, X., Peng, T., Yang, D., Wang, Q., Lv, Z., & Shen, J. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.03.023 · Cited by 34 · see citing works
Goryacheva, A. V., Круглов, С. В., Pshennikova, M. G., Smirin, B. V., Malyshev, I. Y., Barskov, I. V., Викторов, И. В., Downey, H. F., & Manukhina, E. B. (2010) · Nitric Oxide · doi:10.1016/j.niox.2010.08.005 · Cited by 34 · see citing works
Supramolecular fixation of NO2 with calix[4]arenes
Zyryanov, G. V., Kang, Y., Stampp, S. P., & Rudkevich, D. M. (2002) · Chemical Communications · doi:10.1039/b207901a · Cited by 33 · see citing works
Trans-arachidonic acids: new mediators of nitro-oxidative stress
Balazy, M., & Chemtob, S. (2008) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.05.003 · Cited by 33 · see citing works
Polymer-supported calix[4]arenes for sensing and conversion of NO2/N2O4
Kang, Y., & Rudkevich, D. M. (2004) · Tetrahedron · doi:10.1016/j.tet.2004.08.063 · Cited by 33 · see citing works
Qadir, K. W., Mohammadi, M. D., & Abdullah, H. Y. (2024) · Materials Science in Semiconductor Processing · doi:10.1016/j.mssp.2024.108973 · Cited by 32 · see citing works
The impact of nitrite and antioxidants on ultraviolet-A-induced cell death of human skin fibroblasts
Opländer, C., Cortese-Krott, M. M., Korth, H., Kirsch, M., Mahotka, C., Wetzel, W., Pallua, N., & Suschek, C. V. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.05.030 · Cited by 31 · see citing works
Self-citationDecroos, C., Li, Y., Bertho, G., Frapart, Y., Mansuy, D., & Boucher, J. (2009) · Chemical Communications · doi:10.1039/b819259f · Cited by 31 · see citing works
Calix[4]arenes immobilized in a cellulose-based platform for entrapment and detection of NOx gases
Hines, J. H., Wanigasekara, E., Rudkevich, D. M., & Rogers, R. D. (2008) · Journal of Materials Chemistry · doi:10.1039/b803289k · Cited by 31 · see citing works
On the hydrophobicity of nitrogen dioxide: Could there be a “lens” effect for NO2 reaction kinetics?
Squadrito, G. L., & Postlethwait, E. M. (2009) · Nitric Oxide · doi:10.1016/j.niox.2009.05.008 · Cited by 30 · see citing works
van Dalen, C. J., Winterbourn, C. C., & Kettle, A. J. (2006) · Biochemical Journal · doi:10.1042/bj20051470 · Cited by 30 · see citing works
Qadir, K. W., Mohammadi, M. D., Alosfur, F. K. M., & Abdullah, H. Y. (2024) · Journal of Molecular Modeling · doi:10.1007/s00894-024-06252-0 · Cited by 29 · see citing works
Koch, S., Volkmar, C. M., Kolb-Bachofen, V., Korth, H., Kirsch, M., Horn, A. H. C., Sticht, H., Pallua, N., & Suschek, C. V. (2008) · Journal of Molecular Medicine · doi:10.1007/s00109-008-0420-5 · Cited by 29 · see citing works
Self-citationNitrosation of Amides Involves a Pseudopericyclic 1,3-Sigmatropic Rearrangement
Birney, D. M. (2004) · Organic Letters · doi:10.1021/ol049867i · Cited by 29 · see citing works
Pietraforte, D., Castelli, M., Metere, A., Scorza, G., Samoggia, P., Menditto, A., & Minetti, M. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.08.014 · Cited by 29 · see citing works
Rauen, U., Li, T., IOANNIDIS, I., & de GROOT, H. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00366.2006 · Cited by 28 · see citing works
Self-citationForgotten radicals in biology.
Rochette, L., & Vergely, C. (2008) · Europe PMC (PubMed Central) · Cited by 27 · see citing works
Macrophage NOS2 in Tumor Leukocytes
Brüne, B., Courtial, N., Dehne, N., Syed, S. N., & Weigert, A. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6811 · Cited by 28 · see citing works
Towards Supramolecular Fixation of NOX Gases: Encapsulated Reagents for Nitrosation
Kang, Y., Zyryanov, G. V., & Rudkevich, D. M. (2005) · Chemistry - A European Journal · doi:10.1002/chem.200400939 · Cited by 27 · see citing works
Percio, A., Cicchinelli, M., Masci, D., Summo, M., Urbani, A., & Greco, V. (2024) · Antioxidants · doi:10.3390/antiox13080883 · Cited by 24 · see citing works
Kirsch, M., & de GROOT, H. (2004) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2004.00200.x · Cited by 23 · see citing works
Self-citationThe impact ofN‐nitrosomelatonin as nitric oxide donor in cell culture experiments
Berchner‐Pfannschmidt, U., Tug, S., Trinidad, B., Becker, M., Oehme, F., Flamme, I., Fandrey, J., & Kirsch, M. (2008) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2008.00622.x · Cited by 22 · see citing works
Self-citationPetrat, F., Bramey, T., Kirsch, M., & de GROOT, H. (2005) · Free Radical Research · doi:10.1080/10715760500231786 · Cited by 21 · see citing works
Self-citationNitrosonium Complexes of Resorc[4]arenes: Spectral, Kinetic, and Theoretical Studies
Botta, B., D’Acquarica, I., Monache, G. D., Nevola, L., Tullo, D., Ugozzoli, F., & Pierini, M. (2007) · Journal of the American Chemical Society · doi:10.1021/ja072855i · Cited by 21 · see citing works
Kurtikyan, T. S., Gulyan, G. M., Martirosyan, G. G., Lim, M. D., & Ford, P. C. (2005) · Journal of the American Chemical Society · doi:10.1021/ja042237r · Cited by 20 · see citing works
Melatonin nitrosation promoted by radical; comparison with the peroxynitrite reaction
Peyrot, F., Houée‐Levin, C., & Ducrocq, C. (2006) · Free Radical Research · doi:10.1080/10715760600693414 · Cited by 19 · see citing works
Lehnig, M., Kirsch, M., & Korth, H. (2003) · Inorganic Chemistry · doi:10.1021/ic020650z · Cited by 18 · see citing works
Self-citationOpländer, C., Baschin, M., van Faassen, E. E., Born, M., Möller, M., Pallua, N., & Suschek, C. (2010) · Nitric oxide · doi:10.1016/j.niox.2010.08.001 · Cited by 20 · see citing works
Takano, H., Yanagisawa, R., Inoue, K., Shimada, A., Ichinose, T., Sadakane, K., Yoshino, S., Yamaki, K., Morita, M., & Yoshikawa, T. (2004) · Experimental Biology and Medicine · doi:10.1177/153537020422900411 · Cited by 18 · see citing works
Leduc, M., Kermorvant‐Duchemin, E., Checchin, D., Sennlaub, F., Sirinyan, M., Kooli, A., Lachapelle, P., & Chemtob, S. (2006) · Seminars in Perinatology · doi:10.1053/j.semperi.2006.04.004 · Cited by 18 · see citing works
N‐nitroso‐melatonin releases nitric oxide in the presence of serotonin and its derivatives
Kopczak, A., Korth, H., de GROOT, H., & Kirsch, M. (2007) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2007.00484.x · Cited by 18 · see citing works
Self-citationBoccini, F., Domazou, A. S., & Herold, S. (2006) · The Journal of Physical Chemistry A · doi:10.1021/jp056452l · Cited by 17 · see citing works
Six-Coordinate Nitrato Complexes of Iron(III) Porphyrins
Gulyan, G. M., Kurtikyan, T. S., & Ford, P. C. (2007) · Inorganic Chemistry · doi:10.1021/ic702102j · Cited by 17 · see citing works
Hu, T., & Chen, Y.-J. (2010) · Free Radical Research · doi:10.3109/10715761003667570 · Cited by 16 · see citing works
The kinetics of the reaction of nitrogen dioxide with iron(II)- and iron(III) cytochrome c
Domazou, A. S., Gȩbicka, L., Didik, J., Gebicki, J. L., van der Meijden, B., & Koppenol, W. H. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.01.014 · Cited by 16 · see citing works
Desferrioxamine inhibits protein tyrosine nitration: Mechanisms and implications
Adgent, M. A., Squadrito, G. L., Ballinger, C. A., Krzywanski, D. M., Lancaster, J. R., & Postlethwait, E. M. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.06.003 · Cited by 15 · see citing works
Kirsch, M., Korth, H., Wensing, A., Lehnig, M., Sustmann, R., & de GROOT, H. (2006) · Helvetica Chimica Acta · doi:10.1002/hlca.200690222 · Cited by 15 · see citing works
Self-citationOpländer, C., Wetzel, W., Cortese-Krott, M. M., Pallua, N., & Suschek, C. V. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.01.030 · Cited by 14 · see citing works
Swintek, A. U., Christoph, S., Petrat, F. M., de GROOT, H., & Kirsch, M. (2004) · Biological Chemistry · doi:10.1515/bc.2004.079 · Cited by 14 · see citing works
Self-citationChemistry of nitrogen dioxide and its biological implications
Goldstein, S., & Samuni, A. (2024) · Redox Biochemistry and Chemistry · doi:10.1016/j.rbc.2024.100020 · Cited by 13 · see citing works
Kirsch, M., & de GROOT, H. (2007) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2007.00517.x · Cited by 13 · see citing works
Self-citation
- Authors
- Kirsch, M., Korth, H.-G., Sustmann, R., & Groot, H. D.
- Affiliations
- Essen University Hospital (DE)
- Venue
- Biological Chemistry
- Publisher
- Walter de Gruyter GmbH
- Published
- 2002-01-12
- Volume
- 383
- Issue
- 3-4
- Pages
- 389-99
- ISSN
- 1431-6730 (ISSN-L)
- OpenAlex
- W1974264946
- Cited by
- 150
- References
- 110
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 6 · 2022: 4 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 4 · 2017: 1 · 2016: 7 · 2014: 3 · 2013: 2 · 2012: 7
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Keywords
- nitrogen dioxide, free radicals, peroxynitrite, nitrotyrosine, superoxide, vitamin C, antioxidants, glutathione, oxidative stress, nitrosative stress, nitric oxide
- MeSH terms
- Animals, Humans, Nitrogen Dioxide, Oxidants, Photochemical, Peroxynitrous Acid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review