The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Preanalytical quality improvement: from dream to reality
Abstract
Abstract Laboratory diagnostics (i.e., the total testing process) develops conventionally through a virtual loop, originally referred to as "the brain to brain cycle" by George Lundberg. Throughout this complex cycle, there is an inherent possibility that a mistake might occur. According to reliable data, preanalytical errors still account for nearly 60%-70% of all problems occurring in laboratory diagnostics, most of them attributable to mishandling procedures during collection, handling, preparing or storing the specimens. Although most of these would be "intercepted" before inappropriate reactions are taken, in nearly one fifth of the cases they can produce inappropriate investigations and unjustifiable increase in costs, while generating inappropriate clinical decisions and causing some unfortunate circumstances. Several steps have already been undertaken to increase awareness and establish a governance of this frequently overlooked aspect of the total testing process. Standardization and monitoring preanalytical variables is of foremost importance and is associated with the most efficient and well-organized laboratories, resulting in reduced operational costs and increased revenues. As such, this article is aimed at providing readers with significant updates on the total quality management of the preanalytical phase to endeavour further improvement for patient safety throughout this phase of the total testing process.
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Point-of-care testing: state-of-the art and perspectives
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“Preanalytical phase components are the leading causes of poor sample quality, wherein inappropriate or mishandled procedures for collecting blood specimens may be associated with a magnifi ed risk of unsuitable samples (1,2).”
BackgroundSelf-citation
Metadata
- Authors
- Lippi, G., Chance, J. J., Church, S., Dazzi, P., Fontana, R., Giavarina, D., Grankvist, K., Huisman, W., Kouri, T., Palicka, V., Plebani, M., Puro, V., Salvagno, G. L., Sandberg, S., Sikaris, K., Watson, I., Stankovic, A. K., & Simundic, A.-M.
- Venue
- Clinical Chemistry and Laboratory Medicine
- Publisher
- Walter de Gruyter GmbH
- Published
- 2011-01-01
- Volume
- 49
- Issue
- 7
- Pages
- 1113-26
- ISSN
- 1434-6621 (ISSN-L)
- 1437-4331
- OpenAlex
- W1983487843
- Cited by
- 388
- References
- 53
- FWCI
- 18.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lippi, G., Chance, J. J., Church, S., Dazzi, P., Fontana, R., Giavarina, D., Grankvist, K., Huisman, W., Kouri, T., Palicka, V., Plebani, M., Puro, V., Salvagno, G. L., Sandberg, S., Sikaris, K., Watson, I., Stankovic, A. K., & Simundic, A.-M. (2011). Preanalytical quality improvement: from dream to reality. Clinical Chemistry and Laboratory Medicine. https://doi.org/10.1515/cclm.2011.600
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