What Interventions Could Reduce Diagnostic Error in Emergency Departments? A Review of Evidence, Practice and Consumer Perspectives
Abstract
The purpose of this article is to synthesise review evidence, practice and patient perspectives on interventions to reduce diagnostic error in emergency departments (EDs). A rapid review methodology identified nine systematic reviews for inclusion. Six practice interviews were conducted to identify local contextual insights and implementation considerations. Finally, patient perspectives were explored through a citizen panel with 11 participants. The rapid review found evidence for the following interventions: second opinion, decision aids, guided reflection and education. Practitioners suggested three of the four interventions from the academic review: second opinion, decision aids and education. Practitioners suggested four additional interventions: improving teamwork, engaging patients, learning from mistakes and scheduled test follow-up. Patients most favoured interventions that improved communication through education and patient engagement, while also suggesting that implementation of state-wide standards to reduce variability in care and sufficient staffing are important to address diagnostic errors. Triangulating these three perspectives on the evidence allows for the intersections to be highlighted and demonstrates the usefulness of incorporating practitioner reflections and patient values in developing potential interventions.
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Improving information transparency, such as providing easy access to medical information for patients, can bridge the information gap and encourage engagement.
“In addition to strengthening the clinician-patient relationship, improving information transparency [368,369], such as providing easy access to medical information for patients [370], can bridge the information gap and encourage engagement.”
From Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors (2026) · cites this paper as [370]
Cites
Institute of Medicine (2000) · National Academies Press eBooks · doi:10.17226/9728 · Cited by 14,174 · see citing works
Knowledge translation of research findings
Grimshaw, J. M., Eccles, M. P., Lavis, J. N., Hill, S. J., & Squires, J. E. (2012) · Implementation Science · doi:10.1186/1748-5908-7-50 · Cited by 2,407 · see citing works
To Err is Human: Building a Safer Health System in 1999.
Stefl, M. E. (2001) · PubMed · Cited by 1,738 · see citing works
Diagnostic error in internal medicine
Graber, M. L., Franklin, N., & Gordon, R. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.13.1493 · Cited by 1,549 · see citing works
Self-citationImproving Diagnosis in Health Care
Committee on Diagnostic Error in Health Care, Board on Health Care Services, Institute of Medicine, & The National Academies of Sciences, E. (2015) · doi:10.17226/21794 · Cited by 1,376 · see citing works
Overconfidence as a Cause of Diagnostic Error in Medicine
Berner, E. S., & Graber, M. L. (2008) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.01.001 · Cited by 1,034 · see citing works
Self-citationCognitive biases associated with medical decisions: a systematic review
Saposnik, G., Redelmeier, D., Ruff, C. C., & Tobler, P. N. (2016) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-016-0377-1 · Cited by 1,001 · see citing works
Survival From In-Hospital Cardiac Arrest During Nights and Weekends
Peberdy, M. A. (2008) · JAMA · doi:10.1001/jama.299.7.785 · Cited by 586 · see citing works
Understanding triangulation in research
Heale, R., & Forbes, D. (2013) · Evidence Based Nursing · doi:10.1136/eb-2013-101494 · Cited by 567 · see citing works
Cognitive Biases and Heuristics in Medical Decision Making
Blumenthal-Barby, J. S. S., & Krieger, H. (2014) · Medical Decision Making · doi:10.1177/0272989x14547740 · Cited by 554 · see citing works
Consumer involvement in health research: a review and research agenda
Boote, J. D., Telford, R., & Cooper, C. L. (2002) · Health Policy · doi:10.1016/s0168-8510(01)00214-7 · Cited by 506 · see citing works
Cognitive and System Factors Contributing to Diagnostic Errors in Radiology
Lee, C. S., Nagy, P. G., Weaver, S. J., & Newman-Toker, D. E. (2013) · American Journal of Roentgenology · doi:10.2214/ajr.12.10375 · Cited by 415 · see citing works
Shift and night work and long working hours – a systematic review of safety implications
Wagstaff, A. S., & Sigstad Lie, J.-A. (2011) · Scandinavian Journal of Work, Environment & Health · doi:10.5271/sjweh.3146 · Cited by 367 · see citing works
Bornstein, B. H., & Emler, A. C. (2001) · Journal of Evaluation in Clinical Practice · doi:10.1046/j.1365-2753.2001.00284.x · Cited by 353 · see citing works
Tehrani, A. S. S., Lee, H., Mathews, S. C., Shore, A. D., Makary, M. A., Pronovost, P. J., & Newman‐Toker, D. E. (2013) · BMJ Quality & Safety · doi:10.1136/bmjqs-2012-001550 · Cited by 327 · see citing works
Dual-process cognitive interventions to enhance diagnostic reasoning: a systematic review
Lambe, K. A., O'Reilly, G., Kelly, B. D., & Curristan, S. (2016) · BMJ Quality & Safety · doi:10.1136/bmjqs-2015-004417 · Cited by 215 · cited 5× · see citing works
“There were mixed results relating to the provision of meta-cognitive feedback (the provision of feedback on diagnostic reasoning strategies following final diagnosis), with one study finding no effect, a second study finding that cued or modelled reflection increased diagnostic accuracy and a third finding that expert…”
BackgroundResultInfluentialBrief Mindfulness Practices for Healthcare Providers - A Systematic Literature Review.
Gilmartin, H., Goyal, A., Hamati, M. C., Mann, J., Saint, S., & Chopra, V. (2017) · The American Journal of Medicine · doi:10.1016/j.amjmed.2017.05.041 · Cited by 211 · see citing works
Managing diagnostic uncertainty in primary care: a systematic critical review
Alam, R., Cheraghi‐Sohi, S., Panagioti, M., Esmail, A., Campbell, S., & Panagopoulou, E. P. (2017) · BMC Family Practice · doi:10.1186/s12875-017-0650-0 · Cited by 209 · see citing works
The National Emergency Access Target (NEAT) and the 4‐hour rule: time to review the target
Sullivan, C. M., Staib, A. N., Khanna, S., Good, N. M., Boyle, J., Cattell, R., Heiniger, L., Griffin, B. R., Bell, A., Lind, J., et al. (2016) · The Medical Journal of Australia · doi:10.5694/mja15.01177 · Cited by 165 · see citing works
Patient Safety Strategies Targeted at Diagnostic Errors
McDonald, K. M., Matesic, B., Contopoulos‐Ioannidis, D. G., Lonhart, J. A., Schmidt, E. M., Pineda, N., & Ioannidis, J. P. A. (2013) · Annals of Internal Medicine · doi:10.7326/0003-4819-158-5-201303051-00004 · Cited by 140 · see citing works
Riches, N., Panagioti, M., Alam, R., Cheraghi‐Sohi, S., Campbell, S., Esmail, A., & Bower, P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148991 · Cited by 139 · see citing works
Ball, J. R., & Balogh, E. P. (2015) · Annals of Internal Medicine · doi:10.7326/m15-2256 · Cited by 126 · see citing works
Payne, V. L., Singh, H., Meyer, A. N. D., Levy, L., Harrison, D. A., & Graber, M. L. (2014) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2014.02.015 · Cited by 105 · see citing works
Self-citationGraber, M. L., Rusz, D., Jones, M. L., Farm-Franks, D., Jones, B., Gluck, J. C., Thomas, D. B., Gleason, K. T., Welte, K., Abfalter, J., et al. (2017) · Diagnosis · doi:10.1515/dx-2017-0022 · Cited by 98 · see citing works
Self-citationChecklists Improve Experts’ Diagnostic Decisions
Sibbald, M., de Bruin, A. B. H., & van Merrienboer, J. J. G. (2013) · Medical Education · doi:10.1111/medu.12080 · Cited by 92 · see citing works
Diagnostic errors related to acute abdominal pain in the emergency department
Medford-Davis, L. N., Park, E., Shlamovitz, G. Z., Suliburk, J. W., Meyer, A. N. D., & Singh, H. (2015) · Emergency Medicine Journal · doi:10.1136/emermed-2015-204754 · Cited by 85 · see citing works
Shift-to-Shift Handoff Effects on Patient Safety and Outcomes
Mardis, M., Davis, J. J., Benningfield, B., Elliott, C., Youngstrom, M. L., Nelson, B., Justice, E. M., & Riesenberg, L. A. (2015) · American Journal of Medical Quality · doi:10.1177/1062860615612923 · Cited by 78 · see citing works
Collaborative Clinical Reasoning—A Systematic Review of Empirical Studies
Kiesewetter, J., Fischer, F., & Fischer, M. R. (2017) · Journal of Continuing Education in the Health Professions · doi:10.1097/ceh.0000000000000158 · Cited by 61 · see citing works
Differences Between Weekend and Weekday Nurse Work Environments and Patient Outcomes
Hamilton, P., Eschiti, V. S., Hernandez, K., & Neill, D. (2007) · The Journal of Perinatal & Neonatal Nursing · doi:10.1097/01.jpn.0000299791.54785.7b · Cited by 42 · see citing works
Bell, K., Strand, H., & Inder, W. J. (2014) · Archives of Osteoporosis · doi:10.1007/s11657-013-0167-7 · Cited by 39 · see citing works
Gleason, K. T., Davidson, P. M., Tanner, E. K., Baptiste, D., Rushton, C. H., Day, J., Sawyer, M. D., Baker, D. C., Paine, L. A., Himmelfarb, C. D., et al. (2017) · Diagnosis · doi:10.1515/dx-2017-0015 · Cited by 38 · see citing works
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Cited by
Sorted by citations
Gustafsson, S., Gedon, D., Lampa, E., Ribeiro, A. H., Holzmann, M. J., Schön, T. B., & Sundström, J. (2022) · Scientific Reports · doi:10.1038/s41598-022-24254-x · Cited by 65 · see citing works
Beldhuis, I. E., Marapin, R. S., Jiang, Y. Y., Simões de Souza, N. F., Georgiou, A., Kaufmann, T., Castela Forte, J., & van der Horst, I. C. C. (2021) · Journal of Critical Care · doi:10.1016/j.jcrc.2021.04.012 · Cited by 58 · see citing works
Cognitive biases encountered by physicians in the emergency room
Kunitomo, K., Harada, T., & Watari, T. (2022) · BMC Emergency Medicine · doi:10.1186/s12873-022-00708-3 · Cited by 49 · see citing works
Bell, S. K., Bourgeois, F. C., DesRoches, C. M., Dong, J., Harcourt, K., Liu, S. K., Lowe, E., McGaffigan, P., Ngo, L. H., Novack, S. A., et al. (2021) · BMJ Quality & Safety · doi:10.1136/bmjqs-2021-013672 · Cited by 48 · see citing works
‘More than words’ – Interpersonal communication, cognitive bias and diagnostic errors
Dahm, M. R., Williams, M., & Crock, C. (2021) · Patient Education and Counseling · doi:10.1016/j.pec.2021.05.012 · Cited by 38 · see citing works
Diagnostic delays among COVID‐19 patients with a second concurrent diagnosis
Freund, O., Azolai, L., Sror, N., Zeeman, I., Kozlovsky, T., Greenberg, S. A., Weiss, T. E., Bornstein, G., Tchebiner, J. Z., & Frydman, S. (2023) · Journal of Hospital Medicine · doi:10.1002/jhm.13063 · Cited by 24 · see citing works
Gooey, M., Skouteris, H., Betts, J. M., Hatzikiriakidis, K., Sturgiss, E. A., Bergmeier, H. J., & Bragge, P. (2022) · Obesity Reviews · doi:10.1111/obr.13492 · Cited by 23 · see citing works
Self-citationMiller, A. C., Koeneman, S., Arakkal, A. T., Cavanaugh, J. E., & Polgreen, P. M. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab400 · Cited by 15 · see citing works
Patient and public involvement in emergency care research: a scoping review of the literature
Muir, R., Carlini, J., Crilly, J. L., & Ranse, J. (2023) · Emergency Medicine Journal · doi:10.1136/emermed-2022-212514 · Cited by 12 · see citing works
Medical Malpractice and Diagnostic Errors in Japanese Emergency Departments
Miyagami, T., Watari, T., Harada, T., & Naito, T. (2023) · Western Journal of Emergency Medicine · doi:10.5811/westjem.2022.11.55738 · Cited by 12 · see citing works
Mangus, C. W., James, T. G., Parker, S. J., Duffy, E. A., Chandanabhumma, P. P., Cassady, C. M., Bellolio, F., Pasupathy, K. S., Manojlovich, M., Singh, H., et al. (2024) · The Joint Commission Journal on Quality and Patient Safety · doi:10.1016/j.jcjq.2024.03.003 · Cited by 12 · see citing works
Impact of Patient Safety Incidents Reported by the General Public in Korea
Pyo, J., Lee, W. J., Jang, S. G., Choi, E. Y., Ock, M., & Lee, S. (2020) · Journal of Patient Safety · doi:10.1097/pts.0000000000000684 · Cited by 12 · see citing works
Sibbald, M., Abdulla, B., Keuhl, A., Norman, G. R., Monteiro, S., & Sherbino, J. (2022) · JMIR Human Factors · doi:10.2196/39234 · Cited by 11 · see citing works
Manojlovich, M., Bettencourt, A. P., Mangus, C. W., Parker, S. J., Skurla, S. E., Walters, H., & Mahajan, P. (2024) · The Joint Commission Journal on Quality and Patient Safety · doi:10.1016/j.jcjq.2024.01.013 · Cited by 8 · see citing works
Sader, J., Clavien, C., Korris, J. H., Hurst, S., NENDAZ, M. R., & Audétat, M. (2021) · Diagnosis · doi:10.1515/dx-2021-0004 · Cited by 8 · see citing works
Bragge, P., Waddell, A., Kellner, P., Delafosse, V., Marten, R., Nordström, A., & Demaio, S. (2023) · BMJ Global Health · doi:10.1136/bmjgh-2023-011683 · Cited by 7 · see citing works
Self-citationToward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors
Yen, C., Epling, J. W., Rockwell, M., & Vaughn-Cooke, M. (2026) · Diagnostics · doi:10.3390/diagnostics16020347 · Cited by 6 · see citing works
Diagnostic Errors in Japanese Community Hospitals and Related Factors: A Retrospective Cohort Study
Fujimori, T., Ohta, R., & Sano, C. (2023) · Healthcare · doi:10.3390/healthcare11111539 · Cited by 6 · see citing works
Reflection Of Reflections: Building Diagnostic Expertise
Shimizu, T. (2019) · International Journal of General Medicine · doi:10.2147/ijgm.s227859 · Cited by 6 · see citing works
Faulkner, N., Buntine, P., Wright, B., Leach, D. S., & Bragge, P. (2023) · Emergency Medicine Australasia · doi:10.1111/1742-6723.14199 · Cited by 1 · see citing works
Self-citationSafety culture behaviours in construction: A rapid evidence and practice reviewPreprint
Tear, M. J., Curtis, J., Waddell, A., Lennox, A., Grundy, E. A. C., & Bragge, P. (2022) · doi:10.31219/osf.io/vr8g2 · Cited by 1 · see citing works
Self-citationLauren, N., Bragge, P., Waddell, A., Lennox, A., McFarlane, K., & Graham, P. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4837017
Self-citationSolving the mystery of emergency medicine: medically unexplained syndromes
Diószeghy, C., & Prentice, C. (2025) · Frontiers in Disaster and Emergency Medicine · doi:10.3389/femer.2025.1674150
Additional file 1 of Cognitive biases encountered by physicians in the emergency room
Kunitomo, K., Harada, T., & Watari, T. (2022) · Figshare · doi:10.6084/m9.figshare.20678048
Hazboun, R., Ayasa, Y., Omarion, A., Faroun, J., Zghyer, J., Jawabreh, T., & Asbeh, Y. A. A. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1964531
- Authors
- Wright, B., Faulkner, N., Bragge, P., & Graber, M.
- Affiliations
- Monash University (AU)
- RTI International (US)
- Corresponding author
- Wright, Breanna
- Venue
- Diagnosis
- Publisher
- Walter de Gruyter GmbH
- Published
- 2019-05-22
- Volume
- 6
- Issue
- 4
- Pages
- 325-334
- ISSN
- 2194-8011 (ISSN-L)
- 2194-802X
- OpenAlex
- W2946249118
- Cited by
- 25
- References
- 31
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 6 · 2022: 6 · 2021: 5 · 2020: 1 · 2019: 1
- FWCI
- 0.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diagnosis (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Clinical Reasoning and Diagnostic Skills
- Health Sciences › Health Professions › Emergency Medical Services › Patient Safety and Medication Errors
- Health Sciences › Medicine › Emergency Medicine › Emergency and Acute Care Studies
- Keywords
- diagnostic errors, emergency department, second opinion, decision aids, guided reflection, medical education, teamwork, patient engagement, learning from mistakes, patient perspectives, implementation considerations, staffing, quality standards
- MeSH terms
- Communication, Decision Support Techniques, Diagnostic Errors, Emergency Medicine, Emergency Service, Hospital, Humans, Patient Care Team, Patient Participation, Referral and Consultation, Practice Guidelines as Topic, General Practitioners, Patient Safety
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