Obesity and fertility
Abstract
The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.
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Obesity and its complications are associated with reduced fertility in both women and men.
“It is well known that obesity and its complications are associated with reduced fertility in both women and men [67,68].”
From Mediterranean Diet as an Antioxidant: The Impact on Metabolic Health and Overall Wellbeing (2021) · cites this paper as [68]
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- Authors
- Best, D., & Bhattacharya, S.
- Affiliations
- University of Aberdeen (GB)
- Corresponding author
- Best, Damian
- Venue
- Hormone Molecular Biology and Clinical Investigation
- Publisher
- Walter de Gruyter GmbH
- Published
- 2015-08-18
- Volume
- 24
- Issue
- 1
- Pages
- 5-10
- ISSN
- 1868-1883 (ISSN-L)
- 1868-1891
- OpenAlex
- W2174294520
- Cited by
- 64
- References
- 46
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 3 · 2023: 7 · 2022: 11 · 2021: 11 · 2020: 9 · 2019: 5 · 2018: 4 · 2017: 2 · 2016: 5 · 2014: 1
- FWCI
- 0.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Hormone Molecular Biology and Clinical Investigation (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Keywords
- obesity, female infertility, anovulation, time to pregnancy, oocyte quality, embryonic development, endometrium, weight loss, live birth rate, male infertility, semen quality, endocrine disorders
- MeSH terms
- Female, Humans, Infertility, Male, Obesity, Ovary, Ovulation, Weight Loss, Body Mass Index, Embryonic Development, Overweight, Time-to-Pregnancy
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