Cited by 64Ovarian function and disordersReproductive Health and TechnologiesReproductive Biology and Fertility

Obesity and fertility

Best, Damian, Bhattacharya, Siladitya·2015·Hormone Molecular Biology and Clinical Investigation

Abstract

The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.

Integrity signals

Registry

Crossref · 10.1515/hmbci-2015-0023

Cites

45 of 45 references verified0 citation errors · 0 not checkable

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Authors
Best, D., & Bhattacharya, S.
Affiliations
University of Aberdeen (GB)
Corresponding author
Best, Damian
Venue
Hormone Molecular Biology and Clinical Investigation
Published
2015-08-18
Volume
24
Issue
1
Pages
5-10
ISSN
  • 1868-1883 (ISSN-L)
  • 1868-1891
OpenAlex
W2174294520
Cited by
64
References
46
Citations by year
2026: 4 · 2025: 2 · 2024: 3 · 2023: 7 · 2022: 11 · 2021: 11 · 2020: 9 · 2019: 5 · 2018: 4 · 2017: 2 · 2016: 5 · 2014: 1
FWCI
0.56
Type
journal article
Language
en
Open access
closed
Locations
  • Hormone Molecular Biology and Clinical Investigation (publishedVersion)
  • PubMed (publishedVersion)
  • ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
Keywords
obesity, female infertility, anovulation, time to pregnancy, oocyte quality, embryonic development, endometrium, weight loss, live birth rate, male infertility, semen quality, endocrine disorders
MeSH terms
Female, Humans, Infertility, Male, Obesity, Ovary, Ovulation, Weight Loss, Body Mass Index, Embryonic Development, Overweight, Time-to-Pregnancy

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