Cited by 55Advanced Causal Inference TechniquesOptimal Experimental Design MethodsComplex Network Analysis Techniques

Design and Analysis of Experiments in Networks: Reducing Bias from Interference

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Eckles, Dean, Karrer, Brian, Ugander, Johan·2017·Journal of Causal Inference

Abstract

Abstract Estimating the effects of interventions in networks is complicated due to interference, such that the outcomes for one experimental unit may depend on the treatment assignments of other units. Familiar statistical formalism, experimental designs, and analysis methods assume the absence of this interference, and result in biased estimates of causal effects when it exists. While some assumptions can lead to unbiased estimates, these assumptions are generally unrealistic in the context of a network and often amount to assuming away the interference. In this work, we evaluate methods for designing and analyzing randomized experiments under minimal, realistic assumptions compatible with broad interference, where the aim is to reduce bias and possibly overall error in estimates of average effects of a global treatment. In design , we consider the ability to perform random assignment to treatments that is correlated in the network, such as through graph cluster randomization. In analysis , we consider incorporating information about the treatment assignment of network neighbors. We prove sufficient conditions for bias reduction through both design and analysis in the presence of potentially global interference; these conditions also give lower bounds on treatment effects. Through simulations of the entire process of experimentation in networks, we measure the performance of these methods under varied network structure and varied social behaviors, finding substantial bias reductions and, despite a bias–variance tradeoff, error reductions. These improvements are largest for networks with more clustering and data generating processes with both stronger direct effects of the treatment and stronger interactions between units.

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  • Technical limitations include difficulty in performing cluster-randomized experiments testing for social influence and inability to collect the full feed inventory for a given user.

    “Other technical limitations of our approach include the difficulty in performing cluster-randomized experiments testing for social influence (54), and the inability to collect the full feed inventory for a given user.”

    From Reranking partisan animosity in algorithmic social media feeds alters affective polarization (2025) · cites this paper as [54]

    The Design section describes a limitation of graph-cluster randomization: some clustering methods can increase variance too much to justify their bias reduction. The Discussion also cautions that the clustered designs examined may not apply when the goal is to estimate peer effects themselves. These points support methodological difficulty, but the paper does not establish that such experiments are technically difficult to perform. The feed-inventory limitation is not attached to this citation. (LLM, conf=0.78)

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Research works printed but not linked: 5

  1. Toulis P, Edward K. Estimation of Causal Peer Inflluence E昀ffects Proceedings of The 30th International Conference on Machine Learning. J Mach Learn Res W&CP. 2013;28(3):1489-1497.
  2. Cox DR. Planning of Experiments. Hoboken, New Jersey: Wiley, 1958.
  3. Aronow P, Samii C. Estimating average causal e昀ffects under general interference (Working Paper). 2014. Available at http://arxiv.org/abs/1305.6156. · arXiv
  4. Jackson MO. Social and Economic Networks. Princeton, NJ, USA: Princeton University Press, 2008.
  5. Ugander J, Karrer B, Backstrom L, Marlow C. 2011. Available at http://arxiv.org/abs/1111.4503. · arXiv

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Authors
Eckles, D., Karrer, B., & Ugander, J.
Affiliations
  • Massachusetts Institute of Technology (US)
  • Meta (United States) (US)
  • Stanford University (US)
Venue
Journal of Causal Inference
Published
2016-02-04
Volume
5
Issue
1
ISSN
  • 2193-3677 (ISSN-L)
  • 2193-3685
OpenAlex
W1888549093
Cited by
49
References
42
Citations by year
2025: 3 · 2024: 4 · 2023: 6 · 2022: 2 · 2021: 3 · 2020: 6 · 2019: 5 · 2018: 3 · 2017: 6 · 2016: 7 · 2015: 2 · 2014: 2
FWCI
7.09
Type
journal article
Language
en
Open access
Locations
  • Journal of Causal Inference (publishedVersion, cc-by-nc-nd)
  • arXiv (Cornell University) (submittedVersion)
  • arXiv (Cornell University)
Funders
  • Johns Hopkins University
  • Carnegie Mellon University
  • York University
  • University of California, Davis
  • Stanford Graduate School of Business
Topics
  • Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
  • Social Sciences › Decision Sciences › Management Science and Operations Research › Optimal Experimental Design Methods
  • Physical Sciences › Physics and Astronomy › Statistical and Nonlinear Physics › Complex Network Analysis Techniques
Keywords
randomized experiments, bias mitigation, treatment allocation, causal effect estimation, bias-variance trade-off, network clustering, social behavior

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