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Oral colon-specific therapeutic approaches toward treatment of inflammatory bowel disease

Xiao, Bo, Merlin, Didier·2012·Expert Opinion on Drug Delivery
DOI 10.1517/17425247.2012.730517
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Abstract

Introduction Inflammatory bowel disease (IBD) is a chronic relapsing idiopathic disease. In clinical terms, most patients require lifelong medication associated with possible unpleasant adverse effects. Oral colon-specific drug delivery systems are designed to deliver therapeutic drugs to the inflamed colon to target pathophysiological manifestations of IBD. The aim is to maintain the drug with proper concentration in the inflamed colon, to enhance drug residence time and to minimize drug absorption by healthy tissues. Areas covered This review addresses the main barriers for colon-specific drug delivery from organism, tissue and cell levels, respectively. It also summarizes novel colon-specific therapeutic strategies using microparticles and nanoparticles. Expert opinion Oral colon-specific drug delivery represents a possible approach toward efficient treatment of IBD. As the environment of the gastrointestinal tract is harsh and intricate, this approach requires that drug carriers can respond to specific environmental factors of the inflamed colon, permitting stimulus-responsive release of loaded drugs to specific cells or even into specific organelles within cells.

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Research works printed but not linked: 118

  1. 10.1172/JCI44631 · DOI
  2. 10.1016/S1734-1140(11)70575-8 · DOI
  3. 10.1002/jps.21216 · DOI
  4. 10.1016/j.jconrel.2012.01.028 · DOI
  5. 10.1136/gut.47.1.12 · DOI
  6. 10.1146/annurev.med.51.1.289 · DOI
  7. 10.1038/nri1132 · DOI
  8. 10.3109/08916931003674709 · DOI
  9. 10.1016/j.ijfoodmicro.2006.10.006 · DOI
  10. 10.2174/157016309789869083 · DOI
  11. 10.1152/ajpgi.00477.2011 · DOI
  12. 10.1038/nrgastro.2009.203 · DOI
  13. Iacucci M, 2010, Can J Gastroenterol, 24, 127, 10.1155/2010/586092 · DOI
  14. 10.1016/B978-0-12-391860-4.00019-7 · DOI
  15. 10.1016/j.ijpharm.2010.05.003 · DOI
  16. 10.1517/17425247.2.3.451 · DOI
  17. 10.1053/j.gastro.2011.02.014 · DOI
  18. 10.1016/j.jconrel.2012.01.017 · DOI
  19. 10.1023/A:1015827908309 · DOI
  20. 10.1016/j.addr.2011.10.006 · DOI
  21. 10.1080/10611860600823766 · DOI
  22. 10.1016/j.jconrel.2012.06.003 · DOI
  23. 10.1080/01635589609514442 · DOI · Paper page
  24. 10.1016/j.addr.2011.12.009 · DOI
  25. 10.1371/journal.pone.0021547 · DOI
  26. 10.1016/j.addr.2008.11.002 · DOI
  27. 10.1136/gut.35.3.353 · DOI
  28. 10.1042/bst023104s · DOI
  29. 10.2741/Corfield · DOI
  30. 10.1172/JCI117332 · DOI
  31. 10.1016/0016-5085(95)90340-2 · DOI
  32. 10.1016/j.addr.2004.08.005 · DOI
  33. 10.1002/anie.200803526 · DOI
  34. 10.1016/j.ejpb.2010.06.007 · DOI · Paper page
  35. 10.1038/nrgastro.2010.66 · DOI
  36. 10.1016/j.trsl.2006.11.009 · DOI
  37. 10.1016/j.coph.2011.09.013 · DOI
  38. 10.1016/j.drudis.2011.01.003 · DOI
  39. 10.1016/j.jconrel.2012.05.020 · DOI
  40. 10.1124/pr.58.1.8 · DOI
  41. 10.1083/jcb.200112067 · DOI
  42. 10.1111/j.1600-0854.2005.00293.x · DOI
  43. 10.1016/j.jconrel.2007.12.017 · DOI
  44. 10.1073/pnas.92.16.7297 · DOI
  45. 10.1016/j.jconrel.2011.12.021 · DOI
  46. 10.1016/S0169-409X(03)00075-9 · DOI
  47. 10.1016/j.jconrel.2011.07.041 · DOI
  48. 10.1016/j.ejphar.2009.06.069 · DOI
  49. 10.1016/j.biomaterials.2009.02.009 · DOI
  50. 10.1016/j.jconrel.2010.12.009 · DOI
  51. 10.1038/71889 · DOI
  52. 10.1038/mi.2011.49 · DOI
  53. 10.1016/j.addr.2004.08.011 · DOI
  54. 10.1517/17425247.3.5.583 · DOI
  55. 10.2174/187221107779814122 · DOI
  56. 10.1211/jpp.60.10.0005 · DOI
  57. 10.1007/BF01297074 · DOI
  58. 10.1136/gut.48.4.571 · DOI
  59. Sasaki Y, 1997, Am J Gastroenterol, 92, 114
  60. 10.3109/10611869808997884 · DOI
  61. Reddy SN, 1991, Gastroenterology, 101, 1289, 10.1016/0016-5085(91)90079-Z · DOI
  62. 10.1007/BF02220454 · DOI
  63. Eastwood MA, 1975, Clin Gastroenterol, 4, 85, 10.1016/S0300-5089(21)00099-7 · DOI
  64. 10.1002/jps.10414 · DOI
  65. 10.1016/0378-5173(92)90245-W · DOI
  66. Urayama S, 1997, Inflamm Bowel Dis, 3, 114, 10.1097/00054725-199706000-00006 · DOI
  67. 10.1124/jpet.105.088146 · DOI
  68. 10.1016/j.ejpb.2005.08.006 · DOI
  69. 10.1016/j.ejpb.2010.06.013 · DOI
  70. 10.1016/j.ejpb.2004.01.003 · DOI
  71. Mura C, 2011, Int J Pharm, 416, 145
  72. 10.1211/0022357011776658 · DOI
  73. 10.1016/S0168-3659(00)00331-X · DOI
  74. 10.1016/j.ejpb.2007.06.016 · DOI
  75. 10.1016/j.ijpharm.2007.07.007 · DOI
  76. 10.1016/j.cocis.2010.12.005 · DOI
  77. 10.1016/j.ejpb.2008.12.013 · DOI
  78. Kountouras J, 2001, Hepatol Gastroenterol, 48, 743
  79. 10.1186/1476-9255-5-20 · DOI
  80. Naito Y, Suematsu M, Yoshikawa T. Free radical biology in digestive diseases. Karger, Basel; 2011. p. 12-22 · DOI
  81. 10.1007/978-3-0348-8482-2 · DOI
  82. 10.1038/nmat2859 · DOI
  83. 10.1126/science.1149859 · DOI
  84. 10.1016/j.jconrel.2005.11.001 · DOI
  85. 10.1016/j.jconrel.2010.10.002 · DOI
  86. 10.1016/j.jconrel.2012.04.036 · DOI
  87. 10.1016/j.jconrel.2007.03.006 · DOI
  88. 10.1208/s12249-007-9021-9 · DOI
  89. 10.1038/gt.2008.67 · DOI
  90. 10.1038/ctg.2011.1 · DOI
  91. 10.1016/j.colsurfb.2011.10.053 · DOI
  92. 10.1016/j.carbpol.2010.07.032 · DOI
  93. 10.1007/s10856-008-3622-z · DOI
  94. 10.1053/j.gastro.2009.11.003 · DOI
  95. 10.1016/j.biomaterials.2010.09.062 · DOI
  96. 10.1002/ibd.21469 · DOI
  97. 10.1096/fj.06-6801com · DOI
  98. 10.1016/S0092-8674(00)80465-1 · DOI
  99. 10.1038/sj.cgt.7700758 · DOI
  100. 10.1038/sj.gt.3302493 · DOI
  101. 10.1126/science.289.5483.1352 · DOI · Paper page
  102. 10.1146/annurev.iy.11.040193.001121 · DOI
  103. 10.1038/nbt840 · DOI
  104. 10.1016/j.cgh.2006.03.028 · DOI · Paper page
  105. 10.1186/1475-2859-10-S1-S4 · DOI
  106. 10.1002/ibd.21565 · DOI
  107. 10.3168/jds.S0022-0302(90)78988-6 · DOI
  108. 10.1038/2625 · DOI
  109. 10.1186/1472-6750-7-83 · DOI
  110. 10.1016/j.jconrel.2012.02.006 · DOI
  111. 10.1016/j.ejpb.2008.09.028 · DOI
  112. 10.1016/j.jconrel.2006.09.015 · DOI
  113. Yin YS, 2007, Acta Pharma Sinica, 42, 550
  114. 10.1021/mp9000926 · DOI
  115. 10.1136/gut.28.6.745 · DOI
  116. 10.1371/journal.pone.0024202 · DOI
  117. 10.1152/ajpgi.00385.2006 · DOI
  118. 10.1007/s002329900595 · DOI

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Metadata

Authors
Xiao, B., & Merlin, D.
Venue
Expert Opinion on Drug Delivery
Publisher
Informa UK Limited
Published
2012-10-05
Volume
9
Issue
11
Pages
1393-1407
ISSN
  • 1742-5247
  • 1744-7593
DOI
10.1517/17425247.2012.730517
Cited by
145
References
2
Language
en

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