Applications of biosensing atomic force microscopy in monitoring drug and nanoparticle delivery

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Atomic force microscopy comes of age

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Atomic force microscope study of tumor cell membranes following treatment with anti-cancer drugs

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Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles

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Antibody Linking to Atomic Force Microscope Tips via Disulfide Bond Formation

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Protonated Nanoparticle Surface Governing Ligand Tethering and Cellular Targeting

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Real-Time Monitoring of Cell Elasticity Reveals Oscillating Myosin Activity

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Atomic Force Microscopy in Liquid

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Functionalization of Probe Tips and Supports for Single-Molecule Recognition Force Microscopy

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Probing cellular microenvironments and tissue remodeling by atomic force microscopy

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Applied Scanning Probe Methods V

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Handbook of Molecular Force Spectroscopy

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Application of atomic force microscopy to characterize liposomes as drug and gene carriers

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The effect of raft lipid depletion on microvilli formation in MDCK cells, visualized by atomic force microscopy

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Probing cytoskeletal structures by coupling optical superresolution and AFM techniques for a correlative approach

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Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells

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Clusterization of Nanoparticles During Their Interaction with Living Cells

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Force spectroscopy 101: how to design, perform, and analyze an AFM-based single molecule force spectroscopy experiment

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Histamine Effects on Endothelial Cell Fibronectin Interaction Studied by Atomic Force Microscopy

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Atomic force microscopy imaging of novel type of polymeric colloidal nanostructures

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A tip for diagnosing cancer

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A combined optical and atomic force microscope for live cell investigations

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Probing Binding Pocket of Serotonin Transporter by Single Molecular Force Spectroscopy on Living Cells

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Dendrimer-entrapped gold nanoparticles modified with folic acid for targeted gene delivery applications

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Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans

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Atomic force microscopy as a novel pharmacological tool11Abbreviations: AFM, atomic force microscope; SEMs, scanning electron microscopes; and SNP, single nucleotide polymorphism.

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Poly(lactic-co-glycolic) acid loaded nano-insulin has greater potentials of combating arsenic induced hyperglycemia in mice: Some novel findings

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Recognition Imaging with a DNA Aptamer

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AFM imaging of functionalized carbon nanotubes on biological membranes

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Nanoscale membrane activity of surfactins: Influence of geometry, charge and hydrophobicity

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Targeted Delivery of siRNA into Breast Cancer Cells via Phage Fusion Proteins

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Ethambutol-induced alterations inMycobacterium bovisBCG imaged by atomic force microscopy

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Atomic Force Microscopy Study of the Specific Adhesion between a Colloid Particle and a Living Melanoma Cell: Effect of the Charge and the Hydrophobicity of the Particle Surface

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Improved localization of cellular membrane receptors using combined fluorescence microscopy and simultaneous topography and recognition imaging

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Integrated microscopy for real-time imaging of mechanotransduction studies in live cells

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The Influence of Physicochemical Parameters on the Efficacy of Non-Viral DNA Transfection Complexes: A Comparative Study

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Real-time monitoring of angiotensin II-induced contractile response and cytoskeleton remodeling in individual cells by atomic force microscopy

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Fusogenic Tilted Peptides Induce Nanoscale Holes in Supported Phosphatidylcholine Bilayers

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Single Molecular Recognition Force Spectroscopy Study of a Luteinizing Hormone-Releasing Hormone Analogue as a Carcinoma Target Drug

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Atomic Force Microscopy Study of Different Effects of Natural and Semisynthetic β-Lactam on the Cell Envelope of Escherichia coli

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Effect of selected drugs used in asthma treatment on morphology and elastic properties of red blood cells

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On the design of in situ forming biodegradable parenteral depot systems based on insulin loaded dialkylaminoalkyl-amine-poly(vinyl alcohol)-g-poly(lactide-co-glycolide) nanoparticles

Packhaeuser, C. B., & Kissel, T. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.08.004 · Cited by 35 · see citing works

Mapping specific adhesive interactions on living human intestinal epithelial cells with atomic force microscopy

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Imaging and analysis of Bacillus anthracis spore germination

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High-resolution imaging using a novel atomic force microscope and confocal laser scanning microscope hybrid instrument: essential sample preparation aspects

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Detection of metal binding sites on functional S-layer nanoarrays using single molecule force spectroscopy

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Single-Molecule AFM Characterization of Individual Chemically Tagged DNA Tetrahedra

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“Seeing and Counting” Individual Antigens Captured on a Microarrayed Spot with Force-Based Atomic Force Microscopy

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The Biologically Important Surfactin Lipopeptide Induces Nanoripples in Supported Lipid Bilayers

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Characterization of Enhanced Monovalent and Bivalent Thrombin DNA Aptamer Binding Using Single Molecule Force Spectroscopy

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Probing drug-cell interactions

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Particle synergy and aerosol performance in non-aqueous liquid of two combinations metered dose inhalation formulations: An AFM and Raman investigation

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Self-assembled supramolecular nano vesicles for safe and highly efficient gene delivery to solid tumors

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Activation induced morphological changes and integrin αIIbβ3 activity of living platelets

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AFM imaging of functionalized double-walled carbon nanotubes

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Atomic Force Microscopy Images Label-Free, Drug Encapsulated Nanoparticles In Vivo and Detects Difference in Tissue Mechanical Properties of Treated and Untreated: A Tip for Nanotoxicology

Lamprou, D. A., Venkatpurwar, V. P., & Kumar, M. N. V. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064490 · Cited by 28 · see citing works

Effect of thrombin and bradykinin on endothelial cell mechanical properties monitored through membrane deformation

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Progesterone induces nano‐scale molecular modifications on endometrial epithelial cell surfaces

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Adhesion of melanoma cells to the surfaces of microspheres studied by atomic force microscopy

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Chemical Modifications of Atomic Force Microscopy Tips

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Optimal evaluation of single-molecule force spectroscopy experiments

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Single‐Molecule Analysis of the Recognition Forces Underlying Nucleo‐Cytoplasmic Transport

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A single-molecule approach to explore binding, uptake and transport of cancer cell targeting nanotubes

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Decoding distinct membrane interactions of HIV-1 fusion inhibitors using a combined atomic force and fluorescence microscopy approach

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Molecular Recognition Force Spectroscopy: A New Tool to Tailor Targeted Nanoparticles

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Atomic Force Microscopy-based Cell Nanostructure for Ligand-conjugated Quantum Dot Endocytosis

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Leuprorelin Acetate Long-Lasting Effects on GnRH Receptors of Prostate Cancer Cells: An Atomic Force Microscopy Study of Agonist/Receptor Interaction

Lama, G., Papi, M., Angelucci, C., Maulucci, G., Sica, G., & Spirito, M. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0052530 · Cited by 16 · see citing works

Probing microbubble targeting with atomic force microscopy

Sboros, V., Glynos, E., Ross, J. A., MORAN, C. M., Pye, S. D., Butler, M. B., McDicken, W. N., Brown, S. B., & Koutsos, V. (2010) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2010.05.022 · Cited by 15 · see citing works

Continuous capacitance–voltage spectroscopy mapping for scanning microwave microscopy

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Characterization of the mechanisms of HIV-1 Vpr(52–96) internalization in cells

Greiner, V. J., Shvadchak, V. V., Fritz, J. V., Arntz, Y., Didier, P., Frisch, B., Boudier, C., Mély, Y., & de ROCQUIGNY, H. (2011) · Biochimie · doi:10.1016/j.biochi.2011.05.033 · Cited by 10 · see citing works

Towards monitoring transport of single cargos across individual nuclear pore complexes by time-lapse atomic force microscopy

Huang, N., Stubenrauch, M., Köser, J., Taschner, N., Aebi, U., & Stolz, M. (2010) · Journal of Structural Biology · doi:10.1016/j.jsb.2010.04.004 · Cited by 8 · see citing works

Real-Time Monitoring of the Effects of Telmisartan on Angiotensin II-Induced Mechanical Changes in Live Mesangial Cells Using Atomic Force Microscopy

Jeong, K.-H., Lee, T., Ihm, C., Moon, J.-Y., Lee, G., Park, H., & Lee, S. H. (2012) · Kidney & Blood Pressure Research · doi:10.1159/000339175 · Cited by 8 · see citing works

Direct measurement of drug–enzyme interactions by atomic force microscopy; dihydrofolate reductase and methotrexate

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Adhesion of melanoma cells to the microsphere surface is reduced by exposure to nanoparticles

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Enhanced endocytosis of nano-curcumin in nasopharyngeal cancer cells: An atomic force microscopy study

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Single‐Molecule Analysis of the Recognition Forces Underlying Nucleo‐Cytoplasmic Transport

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AFM Imaging in Physiological Environment: From Biomolecules to Living Cells

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DLS and zeta potential – What they are and what they are not?

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Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

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Recent Advances in Biosensor Technology for Potential Applications – An Overview

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Recent progressive use of atomic force microscopy in biomedical applications

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Nanomaterials based electrochemical nucleic acid biosensors for environmental monitoring: A review

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Nanoscale monitoring of drug actions on cell membrane using atomic force microscopy

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Application of nanomedicine for crossing the blood–brain barrier: Theranostic opportunities in multiple sclerosis

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Elasticity regulates nanomaterial transport as delivery vehicles: Design, characterization, mechanisms and state of the art

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Characterization of the specific interaction between the DNA aptamer sgc8c and protein tyrosine kinase-7 receptors at the surface of T-cells by biosensing AFM

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The stomach, small intestine, and colon-specific gastrointestinal tract delivery systems for bioactive nutrients

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Biosensing, Characterization of Biosensors, and Improved Drug Delivery Approaches Using Atomic Force Microscopy: A Review

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Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components

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An Overview on Recent Advances in Biosensor Technology and its Future Application

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Characterization Methods for Nanoparticle–Skin Interactions: An Overview

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Nanoscale Quantifying the Effects of Targeted Drug on Chemotherapy in Lymphoma Treatment Using Atomic Force Microscopy

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Standardization of research methods employed in assessing the interaction between metallic-based nanoparticles and the blood-brain barrier: Present and future perspectives

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Ampholytic starch excipients for high loaded drug formulations: Mechanistic insights

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Optically Manipulated Microtools to Measure Adhesion of the Nanoparticle-Targeting Ligand Glutathione to Brain Endothelial Cells

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Research progress of treating ulcerative colitis and colon cancer by using oral colon targeted drug delivery system based on polymer micelles

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Overview of Advancement in Biosensing Technology, Including its Applications in Healthcare

Deshmukh, R., & Mishra, S. (2022) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201023666220610163343 · Cited by 12 · see citing works

Biosensors Technological Advancement and Their Biomedical, Agricultural, Environmental and Food Industrial Applications: A Review

Abena, T. (2023) · International Journal on Food Agriculture and Natural Resources · doi:10.46676/ij-fanres.v4i3.160 · Cited by 11 · see citing works

Core-shell structured magnetite carboxymethyl cellulose for cervical cancer treatment by maintaining methotrexate serum concentration

Alizadeh, M. H., & Namazi, H. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.137832 · Cited by 10 · see citing works

Research progress and potential of 3D printing in development of foods for gastrointestinal target: A comprehensive review

Niu, D., Zhang, M., MUJUMDAR, A. S., & Li, J. (2025) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2025.105422 · Cited by 10 · see citing works

Mechanical determination of particle–cell interactions and the associated biomedical applications

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Biosensing Applications of Electrode Materials

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Atomic Force Microscopy as a Tool to Assess the Specificity of Targeted Nanoparticles in Biological Models of High Complexity

Gomes, C. P., Lopes, C. D. F., Leitner, M., Ebner, A., Hinterdorfer, P., & Pêgo, A. P. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700597 · Cited by 8 · see citing works

Atomic Force Microscopy Imaging in Turbid Liquids: A Promising Tool in Nanomedicine

Leitner, M., Seferovic, H., Stainer, S., Buchroithner, B., Schwalb, C. H., Deutschinger, A., & Ebner, A. (2020) · Sensors · doi:10.3390/s20133715 · Cited by 8 · see citing works

Factors affecting the preparation of nanocrystals: characterization, surface modifications and toxicity aspects

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Biomedical Sensing with the Atomic Force Microscope

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Metallic Nanoparticles: Development, Applications, and Future Trends for Alcoholic and Nonalcoholic Beverages

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The role of transporter ectodomains in drug recognition and binding: phlorizin and the sodium–glucose cotransporter

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Breaking Down Tumor Drug Resistance: The Link Between Cell Membrane Changes and Treatment Efficacy

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The bioconjugation of DNA with gold nanoparticles towards the spectrophotometric genosensing of pathogenic bacteria

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Molecular Recognition Force Spectroscopy for Probing Cell Targeted Nanoparticles In Vitro

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Atomic force microscopy: The creator of a new paradigm from nanoscale topography imaging to mechanobiology and medicine

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Progress in measuring the mechanical properties of clinical primary cells using atomic force microscopy

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SUSTAINABLE SYNTHESIS AND CHARACTERIZATION OF TUNABLE AND MULTIPURPOSE NANOCELLULOSE FROM FRESHWATER AQUATIC WEED AS PHARMACEUTICAL EXCIPIENT

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Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy

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New Technologies for Nanoparticles Detection in Foods

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Biosensor and Nanotechnology for Diagnosis of Breast Cancer

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Nanomaterials’ Modified Electrodes for Nucleic Acid Biosensing

Khan, A. B. (2024) · Nanostructure science and technology · doi:10.1007/978-3-031-67176-0_12 · Cited by 1 · see citing works

Role of Solid Nano Dispersion in Drug Delivery

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Physical, Physiological, and Biological Measurements

Sanei, S., Jarchi, D., & Constantinides, A. G. (2020) · Wiley eBooks · doi:10.1002/9781119390060.ch3

Biosensors Technological Advancement and their Biomedical, Agricultural, Environmental and Food Industrial Applications: A Review

Abena, T. (2023) · Nanomedicine & Nanotechnology Open Access · doi:10.23880/nnoa-16000263

The World of Biosensors: A Brief Introduction

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Atomic force microscopy as a novel pharmacological tool11Abbreviations: AFM, atomic force microscope; SEMs, scanning electron microscopes; and SNP, single nucleotide polymorphism.

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Nanoscale monitoring of drug actions on cell membrane using atomic force microscopy

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The potential of atomic force microscopy: from nanoparticle characterization to drug delivery implications

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Recent progressive use of atomic force microscopy in biomedical applications

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Atomic Force Microscopy and pharmacology: From microbiology to cancerology

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