The DOI matches its Crossref record; 99 of the 99 references it cites were found in a registry or an index.
Cross-Linked Hydrogel for Pharmaceutical Applications: A Review
Open accessAbstract
Hydrogels are promising biomaterials because of their important qualities such as biocompatibility, biodegradability, hydrophilicity and non-toxicity. These qualities make hydrogels suitable for application in medical and pharmaceutical field. Recently, a tremendous growth of hydrogel application is seen, especially as gel and patch form, in transdermal drug delivery. This review mainly focuses on the types of hydrogels based on cross-linking and; secondly to describe the possible synthesis methods to design hydrogels for different pharmaceutical applications. The synthesis and chemistry of these hydrogels are discussed using specific pharmaceutical examples. The structure and water content in a typical hydrogel have also been discussed.
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Cites
Encyclopedia of polymer science and engineering
Mark, H., & Kroschwitz, J. I. (1985) · Wiley eBooks · Cited by 5,898
Hydrogel: Preparation, characterization, and applications: A review
Ahmed, E. M. (2015) · Journal of Advanced Research · doi:10.1016/j.jare.2013.07.006 · Cited by 5,800
Hydrogels for Tissue Engineering
Lee, K. Y., & Mooney, D. J. (2001) · Chemical Reviews · doi:10.1021/cr000108x · Cited by 5,277
Hydrogels for biomedical applications
Hoffman, A. S. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00239-3 · Cited by 4,864
Hydrogels in pharmaceutical formulations
Peppas, N. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(00)00090-4 · Cited by 4,011
Hydrogels in drug delivery: Progress and challenges
Hoare, T. R., & Kohane, D. S. (2008) · Polymer · doi:10.1016/j.polymer.2008.01.027 · Cited by 3,776
Hydrogels for biomedical applications
Hoffman, A. S. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.010 · Cited by 3,396
Chitosan-based hydrogels for controlled, localized drug delivery
Bhattarai, N., Gunn, J., & Zhang, M. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.07.019 · Cited by 2,451
Berger, J., Reist, M., Mayer, J. M., Felt, O., Peppas, N. A., & Gurny, R. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(03)00161-9 · Cited by 2,163
Novel crosslinking methods to design hydrogels
Hennink, W. E., & van Nostrum, C. F. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00240-x · Cited by 1,962
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Hydrogels as artificial matrices for cell seeding in microfluidic devices
Akther, F., Little, P., Li, Z., Nguyen, N.-T., & Ta, H. T. (2020) · RSC Advances · doi:10.1039/d0ra08566a · Cited by 127
Yee Kuen, C., & Masarudin, M. J. (2022) · Molecules · doi:10.3390/molecules27020473 · Cited by 78
Injectable hydrogels as emerging drug-delivery platforms for tumor therapy
Cheng, Y., Zhang, H., Wei, H., & Yu, C.-Y. (2024) · Biomaterials Science · doi:10.1039/d3bm01840g · Cited by 65
Kurhade, R. R., Shaikh, M. S., Nagulwar, V., & Kale, M. A. (2025) · International Journal of Polymeric Materials and Polymeric Biomaterials · doi:10.1080/00914037.2024.2391973 · Cited by 55
Metadata
- Authors
- parhi, R.
- Venue
- Advanced Pharmaceutical Bulletin
- Publisher
- Maad Rayan Publishing Company
- Published
- 2017-12-31
- Volume
- 7
- Issue
- 4
- Pages
- 515-530
- ISSN
- 2228-5881 (ISSN-L)
- 2251-7308
- OpenAlex
- W2783158793
- Cited by
- 543
- References
- 99
- FWCI
- 8.04
- Type
- journal article
- Language
- en
- Open access
- diamond
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
