Cited by 270Antioxidant Activity and Oxidative StressRedox biology and oxidative stressExercise and Physiological Responses

Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

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Ansarin, Khalil, Khoubnasabjafari, Maryam, Jouyban, Abolghasem·2017·BioImpacts

Abstract

Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technical problems and controversial findings in healthy people and some psychiatric disorders reveal that the reliability of MDA as a biomarker of oxidative stress n eeds to be re-evaluated by experts.

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  • Chronically ill patients of all subtypes of schizophrenia have increased levels of malondialdehyde and TBARS in blood cells.

    “Chronically ill patients of all subtypes of schizophrenia have increased levels of malondialdehyde and thiobarbituric acid reactive substances (TBARS) in blood cells (Khoubnasabjafari et al. 2015).”

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Authors
Ansarin, K., Khoubnasabjafari, M., & Jouyban, A.
Affiliations
Tabriz University of Medical Sciences (IR)
Corresponding author
Jouyban, Abolghasem
Venue
BioImpacts
Published
2017-08-23
Volume
5
Issue
3
Pages
123-127
ISSN
  • 2228-5652 (ISSN-L)
  • 2228-5660
OpenAlex
W2281377718
Cited by
270
References
48
Citations by year
2026: 13 · 2025: 22 · 2024: 26 · 2023: 32 · 2022: 41 · 2021: 29 · 2020: 45 · 2019: 19 · 2018: 28 · 2017: 10 · 2016: 5
FWCI
9.85
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Bioimpacts (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords
malondialdehyde, oxidative stress, biomarkers, mental illness, analytical reliability, lipid peroxidation, biomarker validity

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