Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder
Open accessAbstract
Recent data from several reports indicate that free radicals are involved in aetiopathogenesis of many human pathologies including neuropsychiatric disorders such as schizophrenia, bipolar disorder etc. In the present study, we aimed at determining and evaluating levels of malondialdehyde (MDA), a product of lipid peroxidation, and antioxidant enzyme superoxide dismutase (SOD) and glutathione peroxidase (GSH‐Px) activity levels in patients diagnosed with schizophrenia (n = 25) and bipolar disorder (n = 23). The control group was composed of 20 healthy subjects. There was a significant increase in MDA levels of patients with schizophrenia and bipolar disorder compared with controls. SOD and GSH‐Px activity levels were significantly higher in the schizophrenic group compared with controls. SOD activity levels in bipolar the group were significantly higher than controls whereas there were no significant changes in GSH‐Px activity levels in the bipolar group and controls. Significant differences between lipid peroxidation product and antioxidant enzyme (SOD and GSH‐Px) activity levels in schizophrenic and bipolar disorder patients compared with controls leads us to believe that these differences are related to the heterogenities in aetiologies of these disorders. Copyright © 2002 John Wiley & Sons, Ltd.
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Post-mortem tissues from bipolar disorder patients show impaired function of complex I of the mitochondrial respiratory chain.
“Analysis of post-mortem tissues showed an impaired function of complex I of the MRC (mitochondrial respiratory chain) (Kuloglu et al. 2002).”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Kuloglu et al. 2002
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2022) · doi:10.1176/appi.books.9780890425787 · Cited by 23,476 · see citing works
Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.
Paglia, D. E., & Valentine, W. N. (1967) · PubMed · Cited by 10,776 · see citing works
A simple method for clinical assay of superoxide dismutase.
Sun, Y., Oberley, L. W., & Li, Y. (1988) · Clinical Chemistry · doi:10.1093/clinchem/34.3.497 · Cited by 4,537 · see citing works
Stadtman, E. R. (1992) · Science · doi:10.1126/science.1355616 · Cited by 2,701 · see citing works
Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts
Halliwell, B., & Gutteridge, J. M. C. (1986) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(86)90305-x · Cited by 2,038 · see citing works
Oxygen radicals and human disease
CROSS, C. E., HALLIWELL, B., BORISH, E. T., PRYOR, W. A., AMES, B. N., SAUL, R. L., McCORD, J. M., & HARMAN, D. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-107-4-526 · Cited by 1,856 · see citing works
Lipid peroxidation and antioxidants as biomarkers of tissue damage
Gutteridge, J. M. C. (1995) · Clinical Chemistry · doi:10.1093/clinchem/41.12.1819 · Cited by 1,849 · see citing works
Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method
Kei, S. (1978) · Clinica Chimica Acta · doi:10.1016/0009-8981(78)90081-5 · Cited by 1,730 · see citing works
Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method
佐藤, 敬. (1979) · Medical Entomology and Zoology · Cited by 1,520 · see citing works
The antioxidants of human extracellular fluids
Halliwell, B. B., & Gutteridge, J. M. C. (1990) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(90)90510-6 · Cited by 1,338 · see citing works
Oxidative Pathways for Catecholamines in the Genesis of Neuromelanin and Cytotoxic Quinones
GRAHAM, D. G. (1978) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13535-9 · Cited by 1,126 · see citing works
[39] Assay for blood plasma or serum
Yagi, K. (1984) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(84)05042-4 · Cited by 776 · see citing works
Transition metals as catalysts of “autoxidation” reactions
Miller, D. (1990) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(90)90148-c · Cited by 739 · see citing works
Halliwell, B. B. (1989) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1989.tb01779.x · Cited by 468 · see citing works
Vitamin E as an in Vitro and in Vivo Antioxidanta
Burton, G. W., & Ingold, K. U. (1989) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1989.tb14904.x · Cited by 449 · see citing works
Free radical pathology and antioxidant defense in schizophrenia: a review
Mahadik, S. P., & Mukherjee, S. (1996) · Schizophrenia Research · doi:10.1016/0920-9964(95)00049-6 · Cited by 330 · see citing works
Oxygen Radicals and Neuropsychiatric Illness
Lohr, J. B. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810360061009 · Cited by 225 · see citing works
On the origin and significance of neuromelanin.
Dg, G. (1979) · PubMed · Cited by 223 · see citing works
Abdalla, D. S. P., Monteiro, H., Oliveira, J., & Bechara, E. J. H. (1986) · Clinical Chemistry · doi:10.1093/clinchem/32.5.805 · Cited by 168 · see citing works
Baydaş, G., Erçel, E., Canatan, H., Dönder, E., & Akyol, A. (2001) · Cell Biochemistry and Function · doi:10.1002/cbf.897 · Cited by 107 · see citing works
Self-citationRegional Distribution of Glutathione Peroxidase in the Adult Rat Brain
Brannan, T. S., Maker, H. S., Weiss, C., & Cohen, G. (1980) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1980.tb07102.x · Cited by 89 · see citing works
Muakkassah-Kelly, S. F., Andresen, J. W., Shih, J. C., & Hochstein, P. (1982) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(82)91349-3 · Cited by 79 · see citing works
McCreadie, R. G., MacDonald, E., Wiles, D. H., Campbell, G. R., & Paterson, J. R. (1995) · The British Journal of Psychiatry · doi:10.1192/bjp.167.5.610 · Cited by 78 · see citing works
Glutathione peroxidase and CT scan abnormalities in schizophrenia
Buckman, T. D., Kling, A. S., Eiduson, S., Sutphin, M. S., & Steinberg, A. M. (1987) · Biological Psychiatry · doi:10.1016/0006-3223(87)90069-2 · Cited by 68 · see citing works
Buckman, T. D., Kling, A. S., Sutphin, M. S., Steinberg, A., & Eiduson, S. (1990) · Psychiatry Research · doi:10.1016/0165-1781(90)90103-c · Cited by 67 · see citing works
Halifeoğlu, İ., Canatan, H., Üstündağ, B., İlhan, N., & İnanç, F. (2000) · Cell Biochemistry and Function · doi:10.1002/1099-0844(200012)18:4 · Cited by 67 · see citing works
Self-citationÜstündağ, B., Kazez, A., Demirbağ, M., Canatan, H., Halifeoğlu, İ., & Özercan, İ. H. (2000) · Cellular Physiology and Biochemistry · doi:10.1159/000016354 · Cited by 41 · see citing works
Self-citationAutoimmune and Inflammatory Diseases
Leff, J. A. (1994) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-1833-4_15 · Cited by 22 · see citing works
Superoxide dismutase activity in fibroblasts from patients with schizophrenia
Cohen, M. R., Sailer, V., McAmis, B., & Jenkins, P. (1986) · Biological Psychiatry · doi:10.1016/0006-3223(86)90055-7 · Cited by 16 · see citing works
Suppression of interleukin-1 action by phospholipase-A2 inhibitors in helper T lymphocytes.
Sierra-Honigmann, M. R., & Murphy, P. A. (1993) · PubMed · Cited by 14 · see citing works
Cultured skin fibroblasts in schizophrenia: Acute growth and susceptibility to damage
Cohen, M. R., Gutman, R. L., & McAmis, W. (1987) · Psychiatry Research · doi:10.1016/0165-1781(87)90060-6 · Cited by 13 · see citing works
Protective effect of L-carnitine on alcoholic fatty liver in rats
Bahçecioglu, I., Demir, A. R., Üstündağ, B., Ilhan, M., Baydaş, G., Canatan, H., & Özercan, İ. H. (1999) · DSpace - FIRAT (Fırat University) · Cited by 8 · see citing works
Self-citation
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Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging
Jomova, K., Raptova, R., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03562-9 · Cited by 2,638 · see citing works
Oxidative stress in psychiatric disorders: evidence base and therapeutic implications
Ng, F., Berk, M., Dean, O., & Bush, A. I. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707008401 · Cited by 1,069 · see citing works
Telomere length assessment: Biomarker of chronic oxidative stress?
Houben, J. M. J., Moonen, H. J. J., van Schooten, F., & Hageman, G. J. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.10.001 · Cited by 562 · see citing works
Vitamin C in Disease Prevention and Cure: An Overview
Chambial, S., Dwivedi, S., Shukla, K. K., John, P. J., & Sharma, P. (2013) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-013-0375-3 · Cited by 551 · see citing works
Oxidative stress markers in bipolar disorder: A meta-analysis
Andreazza, A. C., Kauer-Sant'Anna, M., Frey, B. N., Bond, D. J., Kapczinski, F., Young, L. T., & Yatham, L. N. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.04.013 · Cited by 526 · see citing works
Berk, M., Copolov, D. L., Dean, O., Lu, K., Jeavons, S., Schapkaitz, I., Anderson-Hunt, M., & Bush, A. I. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.04.022 · Cited by 500 · see citing works
Meta-analysis of oxidative stress in schizophrenia.
Flatow, J., Buckley, P., & Miller, B. J. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.03.018 · Cited by 491 · see citing works
Allostatic load in bipolar disorder: Implications for pathophysiology and treatment
Kapczinski, F. P., Vieta, E., Andreazza, A. C., Frey, B. N., Gomes, F. A., Tramontina, J., Kauer‐Sant’Anna, M., Grassi‐Oliveira, R., & Post, R. M. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.10.005 · Cited by 479 · see citing works
Oxidative stress in schizophrenia: An integrated approach
Bitanihirwe, B. K. Y., & Woo, T.-U. W. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.008 · Cited by 474 · see citing works
Andreazza, A. C., Shao, L., Wang, J.-F., & Young, L. T. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.22 · Cited by 448 · see citing works
Free radicals, antioxidant defense systems, and schizophrenia
Wu, J. Q., Kosten, T. R., & Zhang, X. Y. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.02.015 · Cited by 420 · see citing works
Therapeutic potential of mood stabilizers lithium and valproic acid:Beyond bipolar disorder
Chiu, C.-T., Wang, Z., Hunsberger, J. G., & Chuang, D.-M. (2013) · Pharmacological Reviews · doi:10.1124/pr.111.005512 · Cited by 404 · see citing works
Ranjekar, P. K., Hinge, A. S., Hegde, M. V., Ghate, M. R., Kale, A. A., Sitasawad, S. L., Wagh, U. V., Debsikdar, V. B., & Mahadik, S. P. (2003) · Psychiatry Research · doi:10.1016/s0165-1781(03)00220-8 · Cited by 395 · see citing works
Machado‐Vieira, R., Manji, H. K., & Zarate, C. A. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00714.x · Cited by 370 · see citing works
An updated meta-analysis of oxidative stress markers in bipolar disorder
Brown, N. C., Andreazza, A. C., & Young, L. T. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.04.005 · Cited by 333 · see citing works
Machado‐Vieira, R., Andreazza, A. C., Viale, C. I., Zanatto, V. C., Ceresér, V. H., Vargas, R. D. S., Kapczinski, F. P., Portela, L. V., Souza, D. O., Salvador, M. M., et al. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.05.016 · Cited by 314 · see citing works
Serum S100B and antioxidant enzymes in bipolar patients
Andreazza, A. C., Cassini, C., Rosa, A. R., Leite, M. C., de Almeida, L. M. V., Nardin, P., da Cunha, A. B., Ceresér, K. M. M., Santin, A. M. P., Gottfried, C., et al. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.07.013 · Cited by 307 · see citing works
Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders
Ansarin, K., Khoubnasabjafari, M., & Jouyban, A. (2017) · BioImpacts · doi:10.15171/bi.2015.20 · Cited by 270 · see citing works
Clinical implications of a staging model for bipolar disorders
Kapczinski, F. P., Dias, V. V., Kauer‐Sant’Anna, M., Frey, B. N., Grassi‐Oliveira, R., Colom, F., & Berk, M. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.31 · Cited by 263 · see citing works
Quercetin and the mitochondria: A mechanistic view
de Oliveira, M. R., Nabavi, S. M., Braidy, N., Setzer, W. N., Ahmed, T., & Nabavi, S. F. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.12.014 · Cited by 252 · see citing works
Oxidative Stress in Schizophrenia
Grabnar, I., Vovk, T., Plesničar, B. K., & Boskovic, M. (2011) · Current Neuropharmacology · doi:10.2174/157015911795596595 · Cited by 250 · see citing works
Kunz, M., Gama, C. S., Andreazza, A. C., Salvador, M. M., Ceresér, K. M., Gomes, F. A., Belmonte-de-Abreu, P. S., Berk, M., & Kapczinski, F. P. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.07.001 · Cited by 241 · see citing works
Frey, B. N., Valvassori, S. S., Réus, G. Z., Martins, M. R., Petronilho, F. C., Bardini, K., Dal‐Pizzol, F., Kapczinski, F. P., & Quevedo, J. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0637 · Cited by 238 · see citing works
Antioxidants as potential therapeutics for neuropsychiatric disorders
Pandya, C. D., Howell, K. R., & Pillai, A. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.10.017 · Cited by 222 · see citing works
Shao, L., Young, L. T., & Wang, J. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.052 · Cited by 218 · see citing works
Andreazza, A. C., Kapczinski, F. P., Kauer‐Sant’Anna, M., Walz, J. C., Bond, D. J., Gonçalves, C. A., Young, L. T., & Yatham, L. N. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0935 · Cited by 199 · see citing works
Mitochondria, synaptic plasticity, and schizophrenia.
Ben-Shachar, D., & Laifenfeld, D. (2004) · International review of neurobiology · doi:10.1016/s0074-7742(04)59011-6 · Cited by 193 · see citing works
Zhao, Z., Wang, W., Guo, H., & Zhou, D. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.06.030 · Cited by 187 · see citing works
Glutathione: a novel treatment target in psychiatry
Berk, M., Ng, F., Dean, O., Dodd, S., & Bush, A. I. (2008) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.05.001 · Cited by 183 · see citing works
Antioxidants as Antidepressants
Scapagnini, G., Davinelli, S., Drago, F., LORENZO, A. D., & Oriani, G. (2012) · CNS Drugs · doi:10.2165/11633190-000000000-00000 · Cited by 184 · see citing works
Scaini, G., Rezin, G. T., Carvalho, A. F., STRECK, E. L., Berk, M., & Quevedo, J. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.040 · Cited by 184 · see citing works
Kuloğlu, M., Atmaca, M., Tezcan, E., Geçici, Ö., Tunckol, H., & Üstündağ, B. (2002) · Neuropsychobiology · doi:10.1159/000063573 · Cited by 178 · see citing works
Self-citationIdentifying and treating cognitive impairment in bipolar disorder
Goldberg, J. F., & Chengappa, K. R. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00716.x · Cited by 174 · see citing works
A meta-analysis of oxidative stress markers in schizophrenia
Zhang, M., Zhao, Z., He, L., & Wan, C. (2010) · Science China Life Sciences · doi:10.1007/s11427-010-0013-8 · Cited by 173 · see citing works
The course of nitric oxide and superoxide dismutase during treatment of bipolar depressive episode
Selek, S., Savas, H. A., Gergerlioglu, H. S., Bulbul, F., Uz, E., & Yumru, M. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.08.006 · Cited by 172 · see citing works
Pădurariu, M., Ciobica, A. S., Dobrin, I., & Ștefănescu, C. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.05.088 · Cited by 171 · see citing works
Oxidative stress in early stage Bipolar Disorder and the association with response to lithium
de Sousa, R. T., Zarate, C. A., Zanetti, M. V., Costa, A. C., Talib, L. L., Gattaz, W. F., & Machado-Vieira, R. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.11.011 · Cited by 169 · see citing works
Raffa, M., Atig, F., Mhalla, A., Kerkeni, A., & Mechri, A. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-124 · Cited by 168 · see citing works
Zuccoli, G. S., Saia-Cereda, V. M., Nascimento, J. M., & Martins-de-Souza, D. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00493 · Cited by 157 · see citing works
A systematic review of metabolite biomarkers of schizophrenia
Davison, J., O’Gorman, A., Brennan, L., & Cotter, D. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.09.021 · Cited by 161 · see citing works
Oxidative imbalance in bipolar disorder subtypes: A comparative study
Yumru, M., SAVAS, H. A., Kalenderoğlu, A., Bulut, M., Çelık, H., & Erel, Ö. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.06.005 · Cited by 163 · see citing works
Implications for reactive oxygen species in schizophrenia pathogenesis
Koga, M., Serritella, A. V., Sawa, A., & Sedlak, T. W. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.06.022 · Cited by 159 · see citing works
Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness
Che, Y., Wang, J.-F., Shao, L., & Young, L. T. (2010) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.090083 · Cited by 155 · see citing works
Viral infection, inflammation and schizophrenia
Kneeland, R. E., & Fatemi, S. H. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.02.001 · Cited by 152 · see citing works
McNamara, R. K., Jandacek, R. J., Rider, T., Tso, P., Stanford, K. E., Hahn, C.-G., & Richtand, N. M. (2008) · Psychiatry Research · doi:10.1016/j.psychres.2007.08.021 · Cited by 146 · see citing works
Gigante, A. D., Young, L. T., Yatham, L. N., Andreazza, A. C., Nery, F. G., Grinberg, L. T., Heinsen, H., & Lafer, B. (2010) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114571000146x · Cited by 143 · see citing works
The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment
Giménez-Palomo, A., Dodd, S., Anmella, G., Carvalho, A. F., Scaini, G., Quevedo, J., Pacchiarotti, I., Vieta, E., & Berk, M. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.546801 · Cited by 140 · see citing works
SAVAS, H. A., Gergerlioğlu, H. S., Armutçu, F., Herken, H., Yılmaz, H. R., Koçoğlu, E., Selek, S., Tutkun, H., Zoroğlu, S. S., & Akyol, Ö. (2006) · The World Journal of Biological Psychiatry · doi:10.1080/15622970510029993 · Cited by 143 · see citing works
Oxidative stress markers in affective disorders
Siwek, M., Sowa-Kućma, M., Dudek, D., Styczeń, K., Szewczyk, B., Kotarska, K., Misztak, P., Pilc, A., Wolak, M., & Nowak, G. (2013) · Pharmacological Reports · doi:10.1016/s1734-1140(13)71517-2 · Cited by 142 · see citing works
Antioxidant Enzyme and Malondialdehyde Levels in Patients with Panic Disorder
Kuloğlu, M., Atmaca, M., Tezcan, E., Üstündağ, B., & Bulut, S. (2002) · Neuropsychobiology · doi:10.1159/000067810 · Cited by 137 · see citing works
Self-citationDakhale, G. N., Khanzode, S. D., Khanzode, S. S., & Saoji, A. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0117-1 · Cited by 131 · see citing works
The role of vitamin C in stress-related disorders
Moritz, B., Schmitz, A. E., Rodrigues, A. L. S., Dafré, A. L., & Cunha, M. P. (2020) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2020.108459 · Cited by 133 · see citing works
Oxidative stress in schizophrenia - focusing on the main markers.
Ciobica, A. S., Pădurariu, M., Dobrin, I., Ștefănescu, C., & Dobrin, R. (2011) · PubMed · Cited by 126 · see citing works
Role of oxidative stress in the pathophysiology of bipolar disorder
Steckert, A. V., Valvassori, S. S., Moretti, M., Dal‐Pizzol, F., & Quevedo, J. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0195-2 · Cited by 125 · see citing works
Effects of lithium therapy on Na+–K+-ATPase activity and lipid peroxidation in bipolar disorder
Banerjee, U., Dasgupta, A., Rout, J. K., & Singh, O. P. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.12.006 · Cited by 124 · see citing works
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Frey, B. N., Andreazza, A. C., Kunz, M., Gomes, F. A., Quevedo, J., Salvador, M., Gonçalves, C. A., & Kapczinski, F. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.06.011 · Cited by 120 · see citing works
Targeting Glutamatergic Signaling for the Development of Novel Therapeutics for Mood Disorders
Machado‐Vieira, R., Salvadore, G., Ibrahim, L. A., Diazgranados, N., & Zarate, C. A. (2009) · Current Pharmaceutical Design · doi:10.2174/138161209788168010 · Cited by 117 · see citing works
Oxidative Damage and Schizophrenia: The Potential Benefit by Atypical Antipsychotics
Dakhale, G. N., Khanzode, S. D., Khanzode, S. S., Saoji, A., Khobragade, L., & Turankar, A. V. (2004) · Neuropsychobiology · doi:10.1159/000077368 · Cited by 118 · see citing works
Othmen, L. B., Mechri, A., Fendri, C., Bost, M., Chazot, G., Gaha, L., & Kerkeni, A. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.08.003 · Cited by 117 · see citing works
Oxidative imbalance in child and adolescent patients with attention-deficit/hyperactivity disorder
Ceylan, M. F., Şener, Ş., Bayraktar, A. Ç., & Kavutçu, M. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.08.010 · Cited by 115 · see citing works
Reduced antioxidant defense in early onset first-episode psychosis: a case-control study
Micó, J. A., Rojas-Corrales, M. O., Gibert‐Rahola, J., Parellada, M., Moreno, D. M., Fraguas, D., Graell, M., Gil, J., Irazusta, J., Castro‐Fornieles, J., et al. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-26 · Cited by 114 · see citing works
Changes in nitric oxide level and superoxide dismutase activity during antimanic treatment
Gergerlioğlu, H. S., SAVAS, H. A., Bülbül, F., Selek, S., Uz, E., & Yumru, M. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.12.020 · Cited by 111 · see citing works
Frey, B. N., Martins, M. R., Petronilho, F. C., Dal‐Pizzol, F., Quevedo, J., & Kapczinski, F. P. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00318.x · Cited by 109 · see citing works
Möller, M., du Preez, J. L., Emsley, R. A., & Harvey, B. H. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2010.09.006 · Cited by 103 · see citing works
Rosa, A. R., Frey, B. N., Andreazza, A. C., Ceresér, K. M., Cunha, A. B. M., Quevedo, J., Santin, A. M. P., Gottfried, C., Gonçalves, C. A., Vieta, E., et al. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.08.026 · Cited by 102 · see citing works
Evaluation of antioxidant deficit in schizophrenia
Sharma, P., Dadheech, G., Mishra, S., & Gautam, S. (2008) · Indian Journal of Psychiatry · doi:10.4103/0019-5545.39753 · Cited by 101 · see citing works
Malondialdehyde levels in adult attention-deficit hyperactivity disorder
Bulut, M., Selek, S., Gergerlioğlu, H. S., SAVAS, H. A., Yılmaz, H. R., Yüce, M., & Ekici, G. (2007) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0744 · Cited by 101 · see citing works
Gawryluk, J. W., Wang, J.-F., Andreazza, A. C., Shao, L., Yatham, L. N., & Young, L. T. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711000617 · Cited by 99 · see citing works
Tsugawa, S., Noda, Y., Tarumi, R., Mimura, Y., Yoshida, K., Iwata, Y., ElSalhy, M., Kuromiya, M., Kurose, S., Masuda, F., et al. (2019) · Journal of Psychopharmacology · doi:10.1177/0269881119845820 · Cited by 99 · see citing works
Frey, B. N., Valvassori, S. S., Réus, G. Z., Martins, M. R., Petronilho, F. C., Bardini, K., Dal‐Pizzol, F., Kapczinski, F. P., & Quevedo, J. (2006) · Neurochemical Research · doi:10.1007/s11064-006-9070-6 · Cited by 98 · see citing works
Ahmed, S. S. S. J., & Santosh, W. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011252 · Cited by 99 · see citing works
Reduced antioxidant defense systems in schizophrenia and bipolar I disorder
Raffa, M., Barhoumi, S., Atig, F., Fendri, C., Kerkeni, A., & Mechri, A. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.07.013 · Cited by 95 · see citing works
Emerging roles of brain metabolism in cognitive impairment and neuropsychiatric disorders
Morella, I., Brambilla, R., & Morè, L. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104892 · Cited by 96 · see citing works
Nucifora, L. G., Tanaka, T., Hayes, L. N., Kim, M., Lee, B. J., Matsuda, T., Nucifora, F. C., Sedlak, T. W., Mojtabai, R., Eaton, W. W., et al. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.178 · Cited by 94 · see citing works
Biological hypotheses, risk factors, and biomarkers of schizophrenia
Fišar, Z. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2022.110626 · Cited by 97 · see citing works
Rosa, A. R., Singh, N., Whitaker, E., de Brito, M., Lewis, A. M., Vieta, E., Churchill, G. C., Geddes, J. R., & Goodwin, G. M. (2014) · Psychological Medicine · doi:10.1017/s0033291714000014 · Cited by 91 · see citing works
Beneficial effects of omega-3 fatty acid supplementation in schizophrenia: possible mechanisms
Hsu, M., Huang, Y. S., & Ouyang, W. (2020) · Lipids in Health and Disease · doi:10.1186/s12944-020-01337-0 · Cited by 88 · see citing works
Evaluation of oxidative stress measurements in obstructive sleep apnea syndrome
Jordan, W., Cohrs, S., Degner, D., Meier, A., Rodenbeck, A., Mayer, G., Pilz, J., Rüther, E., Kornhuber, J., & Bleich, S. (2005) · Journal of Neural Transmission · doi:10.1007/s00702-005-0316-2 · Cited by 87 · see citing works
Selek, S., Herken, H., Bulut, M., Ceylan, M. F., Çelık, H., SAVAS, H. A., & Erel, Ö. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.10.002 · Cited by 85 · see citing works
Early intervention in bipolar disorders: Clinical, biochemical and neuroimaging imperatives
Berk, M., Malhi, G. S., Hallam, K. T., Gama, C. S., Dodd, S., Andreazza, A. C., Frey, B. N., & Kapczinski, F. P. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.08.011 · Cited by 80 · see citing works
Du, Y., Chen, L., Li, X.-S., Li, X., Xu, X., Tai, S., Yang, G.-L., Tang, Q., Liu, H., Liu, S., et al. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa166 · Cited by 82 · see citing works
Andreazza, A. C., & Young, L. T. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000096 · Cited by 80 · see citing works
Harvey, B. H., Joubert, C., du Preez, J. L., & Berk, M. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9466-y · Cited by 81 · see citing works
Serum Oxidative Stress Marker Levels in Unmedicated and Medicated Patients with Schizophrenia
Bai, Z., Li, X., Chen, G.-Y., Du, Y., Wei, Z., Chen, X., Zheng, G.-E., Deng, W., & Cheng, Y. (2018) · Journal of Molecular Neuroscience · doi:10.1007/s12031-018-1165-4 · Cited by 78 · see citing works
TRPC Channels and their Implications for Neurological Diseases
Selvaraj, S., Sun, Y., & Singh, B. B. (2010) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152710790966650 · Cited by 77 · see citing works
Antioxidant enzyme and malondialdehyde values in social phobia before and after citalopram treatment
Atmaca, M., Tezcan, E., Kuloglu, M., Ustundag, B., & Tunckol, H. (2004) · European Archives of Psychiatry and Clinical Neurosciences · doi:10.1007/s00406-004-0484-3 · Cited by 75 · see citing works
Self-citationThe neurobiology of suicide - A Review of post-mortem studies
Furczyk, K., Schutová, B., Michel, T. M., Thome, J., & Büttner, A. (2013) · Journal of Molecular Psychiatry · doi:10.1186/2049-9256-1-2 · Cited by 78 · see citing works
Zhang, Y., Liang, F., Zhang, D., Qi, S., & Liu, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114046 · Cited by 74 · see citing works
Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide in schizophrenia
Zhang, X., Zhou, D. F., Shen, Y., Zhang, P. Y., Zhang, W. F., Liang, J., Chen, D. C., Xiu, M. H., Kosten, T. A., & Kosten, T. R. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.12.014 · Cited by 74 · see citing works
Chang, C., Jou, S., Lin, T., & Liu, C. (2014) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12163 · Cited by 72 · see citing works
Free radicals in patients with post-traumatic stress disorder
Tezcan, E., Atmaca, M., Kuloğlu, M., & Üstündağ, B. (2003) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-003-0413-x · Cited by 72 · see citing works
Self-citationDorsal Anterior Cingulate Lactate and Glutathione Levels in Euthymic Bipolar I Disorder:1H-MRS Study
Soeiro‐de‐Souza, M. G., Pastorello, B., Leite, C. D. C., Henning, A., Moreno, R. A., & Otaduy, M. C. G. (2016) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyw032 · Cited by 70 · see citing works
Pazvantoğlu, O., Selek, Ş., Okay, İ. T., Şengül, C., Karabekiroğlu, K., Dılbaz, N., & Erel, Ö. (2009) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2009.02015.x · Cited by 69 · see citing works
Bengesser, S., Lackner, N., Birner, A., Fellendorf, F. T., Platzer, M., Mitteregger, A., Unterweger, R., Reininghaus, B., Mangge, H., Wallner-Liebmann, S. J., et al. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.10.014 · Cited by 68 · see citing works
Cecerska-Heryć, E., Polikowska, A., Serwin, N., Roszak, M., Grygorcewicz, B., Heryć, R., Michalczyk, A., & Dołęgowska, B. (2022) · Neurochemistry International · doi:10.1016/j.neuint.2021.105269 · Cited by 68 · see citing works
Reactive Oxygen Species: Angels and Demons in the Life of a Neuron
Biswas, K., Alexander, K. D., & Francis, M. M. (2022) · NeuroSci · doi:10.3390/neurosci3010011 · Cited by 69 · see citing works
Phillips, C. (2017) · Neural Plasticity · doi:10.1155/2017/7014146 · Cited by 65 · see citing works
Al-chalabi, B. M., Thanoon, I. A. J., & Ahmed, F. A. (2009) · Neuropsychobiology · doi:10.1159/000202823 · Cited by 66 · see citing works
Chiu, C., Scheuing, L., Liu, G., Liao, H., Linares, G. R., Lin, D. H., & Chuang, D. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyu102 · Cited by 66 · see citing works
Patel, S., Sharma, D., Kalia, K., & Tiwari, V. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.08.025 · Cited by 64 · see citing works
- Authors
- Kuloglu, M., Ustundag, B., Atmaca, M., Canatan, H., Tezcan, A. E., & Cinkilinc, N.
- Affiliations
- Fırat University (TR)
- Venue
- Cell Biochemistry and Function
- Publisher
- Wiley
- Published
- 2002-01-18
- Volume
- 20
- Issue
- 2
- Pages
- 171-175
- ISSN
- 0263-6484 (ISSN-L)
- 1099-0844
- OpenAlex
- W2159813509
- Cited by
- 321
- References
- 33
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 3 · 2023: 9 · 2022: 12 · 2021: 7 · 2020: 13 · 2019: 9 · 2018: 8 · 2017: 13 · 2016: 24 · 2015: 19 · 2014: 26 · 2013: 26 · 2012: 20
- FWCI
- 3.09
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Cell Biochemistry and Function (publishedVersion)
- PubMed (publishedVersion)
- DSpace - FIRAT (Fırat University) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Keywords
- lipid peroxidation, antioxidant enzymes, schizophrenia, bipolar disorder, malondialdehyde, superoxide dismutase, glutathione peroxidase, free radicals, oxidative stress, neuropsychiatric disorders
- MeSH terms
- Antioxidants, Bipolar Disorder, Glutathione Peroxidase, Humans, Malondialdehyde, Schizophrenia, Superoxide Dismutase, Lipid Peroxidation
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