Cited by 171Neural and Behavioral Psychology StudiesMemory and Neural MechanismsNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.

Basolateral Amygdala to Orbitofrontal Cortex Projections Enable Cue-Triggered Reward Expectations

Open access

Lichtenberg, Nina T., Pennington, Zachary T., Holley, Sandra M., Greenfield, Venuz Y., Cepeda, Carlos, Levine, Michael S., Wassum, Kate M.·2017·The Journal of Neuroscience

DOI 10.1523/jneurosci.0486-17.2017PMC PMC5577854

Open this paper in CoChat — free account Open PDF

Abstract

To make an appropriate decision, one must anticipate potential future rewarding events, even when they are not readily observable. These expectations are generated by using observable information (e.g., stimuli or available actions) to retrieve often quite detailed memories of available rewards. The basolateral amygdala (BLA) and orbitofrontal cortex (OFC) are two reciprocally connected key nodes in the circuitry supporting such outcome-guided behaviors. But there is much unknown about the contribution of this circuit to decision making, and almost nothing known about the whether any contribution is via direct, monosynaptic projections, or the direction of information transfer. Therefore, here we used designer receptor-mediated inactivation of OFC→BLA or BLA→OFC projections to evaluate their respective contributions to outcome-guided behaviors in rats. Inactivation of BLA terminals in the OFC, but not OFC terminals in the BLA, disrupted the selective motivating influence of cue-triggered reward representations over reward-seeking decisions as assayed by Pavlovian-to-instrumental transfer. BLA→OFC projections were also required when a cued reward representation was used to modify Pavlovian conditional goal-approach responses according to the reward9s current value. These projections were not necessary when actions were guided by reward expectations generated based on learned action-reward contingencies, or when rewards themselves, rather than stored memories, directed action. These data demonstrate that BLA→OFC projections enable the cue-triggered reward expectations that can motivate the execution of specific action plans and allow adaptive conditional responding. SIGNIFICANCE STATEMENT Deficits anticipating potential future rewarding events are associated with many psychiatric diseases. Presently, we know little about the neural circuits supporting such reward expectation. Here we show that basolateral amygdala to orbitofrontal cortex projections are required for expectations of specific available rewards to influence reward seeking and decision making. The necessity of these projections was limited to situations in which expectations were elicited by reward-predictive cues. These projections therefore facilitate adaptive behavior by enabling the orbitofrontal cortex to use environmental stimuli to generate expectations of potential future rewarding events.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1523/jneurosci.0486-17.2017

Cites

95 of 95 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
AChE-stained horizontal sections of the rat brain in stereotaxic coordinates
Paxinos, G., WATSON, C. R. R., & Emson, P. C. (1980) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(80)90021-7 · Cited by 4,501
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
Goldstein, R. Z., & Volkow, N. D. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3119 · Cited by 2,749 · cited 1×
“Disrupted amygdala and OFC activity and connectivity have also been associated with these diseases (Ressler and Mayberg, 2007; Price and Drevets, 2010; Goldstein and Volkow, 2011; Passamonti et al., 2012; Liu et al., 2014; Sladky et al., 2015).”
The Organization of Networks within the Orbital and Medial Prefrontal Cortex of Rats, Monkeys and Humans
Ongur, D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.206 · Cited by 2,627
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
Armbruster, B. N., Li, X., Pausch, M. H., Herlitze, S., & Roth, B. L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700293104 · Cited by 2,046
Neurocircuitry of Mood Disorders
Price, J. L., & Drevets, W. C. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.104 · Cited by 1,606 · cited 1×
“Disrupted amygdala and OFC activity and connectivity have also been associated with these diseases (Ressler and Mayberg, 2007; Price and Drevets, 2010; Goldstein and Volkow, 2011; Passamonti et al., 2012; Liu et al., 2014; Sladky et al., 2015).”
Goal-directed instrumental action: contingency and incentive learning and their cortical substrates
Balleine, B. W., & Dickinson, A. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00033-1 · Cited by 1,541
Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys
Carmichael, S. T., & Price, J. L. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903630408 · Cited by 1,197
Encoding Predictive Reward Value in Human Amygdala and Orbitofrontal Cortex
Gottfried, J. A., O'Doherty, J., & Dolan, R. J. (2003) · Science · doi:10.1126/science.1087919 · Cited by 1,165
Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic
Ressler, K. J., & Mayberg, H. S. (2007) · Nature Neuroscience · doi:10.1038/nn1944 · Cited by 1,007

Show all 95 references

Sorted by citations

Items 101–170 of 170

Optogenetic activation of basolateral amygdala-to-nucleus accumbens core neurons promotes Pavlovian approach responses but not instrumental pursuit of reward cues
Servonnet, A., Rompré, P.-P., & Samaha, A. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.114254 · Cited by 9
Dopamine in the dorsal bed nucleus of stria terminalis signals Pavlovian sign-tracking and reward violations
Gyawali, U., Martin, D. A., Sun, F., Li, Y., & Calu, D. J. (2023) · eLife · doi:10.7554/elife.81980 · Cited by 9
Offline orbitofrontal cortex reactivation depends on recency of place-reward changes and coheres with hippocampal replay
Rusu, S. I., Bos, J. J., Marchesi, P., Lankelma, J. V., Pica, I. F., Gentet, L. J., Joëls, M., & Pennartz, C. M. A. (2024) · iScience · doi:10.1016/j.isci.2024.109205 · Cited by 7
Acute, but not longer‐term, exposure to environmental enrichment attenuates Pavlovian cue‐evoked conditioned approach and Fos expression in the prefrontal cortex in mice
Margetts‐Smith, G., Macnaghten, A. I., Brebner, L. S., Ziminski, J. J., Sieburg, M. C., Grimm, J. W., Crombag, H. S., & Koya, E. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15146 · Cited by 9
Value-free reinforcement learning: Policy optimization as a minimal model of operant behaviorPreprint
Bennett, D., Niv, Y., & Langdon, A. (2021) · doi:10.31234/osf.io/ew58m · Cited by 13
A novel hypothalamic-midbrain circuit for model-based learningPreprint
Hoang, I. B., Munier, J. J., Verghese, A., Greer, Z., Millard, S. J., DiFazio, L. E., Sercander, C., Izquierdo, A., & Sharpe, M. J. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.02.530856 · Cited by 8
Pathway-Specific Chemogenetic Manipulation by Applying Ligand to Axonally Expressed DREADDs
Martinez, M. X., Farrell, M. R., & Mahler, S. V. (2023) · Neuromethods · doi:10.1007/978-1-0716-2918-5_11 · Cited by 8
Altered connectivity patterns of medial and lateral orbitofrontal cortex underlie the severity of bulimic symptoms
Li, W., Chen, X., Luo, Y., Xiao, M., Liu, Y., & Chen, H. (2024) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2024.100439 · Cited by 8
Outcome devaluation by specific satiety disrupts sensory-specific Pavlovian-to-instrumental transfer
Panayi, M. C., & Killcross, S. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.983480 · Cited by 8
Involvement of cortical projections to basolateral amygdala in context-induced reinstatement of ethanol-seeking in rats
Tavares, G. E. B., Bianchi, P., Yokoyama, T. S., Palombo, P., & Cruz, F. C. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114435 · Cited by 9
Learning what to expect and when to expect it involves dissociable neural systems
Delamater, A. R., Chen, B., Nasser, H. M., & Elayouby, K. S. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.02.026 · Cited by 8
Ethanol modulation of cortico-basolateral amygdala circuits: Neurophysiology and behavior
McCool, B. A. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108750 · Cited by 7
Action inflexibility and compulsive-like behavior accompany neurobiological alterations in the anterior orbitofrontal cortex and associated striatal nuclei
Butkovich, L. M., Yount, S. T., Allen, A. T., Seo, E. H., Swanson, A. M., & Gourley, S. L. (2025) · Scientific Reports · doi:10.1038/s41598-024-84369-1 · Cited by 7
The influence of predictive learning on choice and decision-making and its neural bases
Leung, B. K., Laurent, V., & Balleine, B. W. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15754-7.00067-5 · Cited by 5
Altered neuronal response to visual food stimuli in adolescents undergoing chronic sleep restriction
DiFrancesco, M. W., Alsameen, M. H., St‐Onge, M., Duraccio, K. M., & Beebe, D. W. (2023) · SLEEP · doi:10.1093/sleep/zsad036 · Cited by 6
Encoding of predictive associations in human prefrontal and medial temporal neurons during Pavlovian appetitive conditioning
Aquino, T. G., Courellis, H. S., Mamelak, A. N., Rutishauser, U., & O’Doherty, J. P. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1628-23.2024 · Cited by 7
Prefrontal pathways provide top down control of memory for sequences of eventsPreprint
Jayachandran, M., Linley, S. B., Schlecht, M., Mahler, S. V., Vertes, R. P., & Allen, T. A. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/508051 · Cited by 6
Projecting neurons from the lateral entorhinal cortex to the basolateral amygdala mediate the encoding of incidental odor–taste associations
González-Parra, J. A., Acciai, V., Vidal-Palencia, L., Canela-Grimau, M., & Busquets-García, A. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2502127122 · Cited by 7
A bioinspired model to motivate learning of appetitive signals’ incentive value under a Pavlovian conditioning approach
Muñoz-Capote, A., Gómez-Martínez, D. G., Flores, T. D. C. R., Robles, F., Ramos, M. A., & Ramos, F. (2022) · Neurocomputing · doi:10.1016/j.neucom.2022.05.104 · Cited by 5
Dopamine Supports Reward Prediction to Shape Reward-Pursuit Strategy
Malvaez, M., Suarez, A., Griffin, N. K., Ramírez-Armenta, K., Ostlund, S. B., & Wassum, K. M. (2026) · Journal of Neuroscience · doi:10.1523/jneurosci.1636-25.2026 · Cited by 7
Self-citation
Medial Orbitofrontal, Prefrontal, and Amygdalar Circuits Support Dissociable Component Processes of Risk/Reward Decision-Making
Jenni, N. L., Bercovici, D. A., & Floresco, S. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.2147-24.2025 · Cited by 4
Dopaminergic responses to identity prediction errors depend differently on the orbitofrontal cortex and hippocampus.
Takahashi, Y. K., Zhang, Z., Kahnt, T., & Schoenbaum, G. M. (2025) · Behavioral Neuroscience · doi:10.1037/bne0000633 · Cited by 4
Evolutionary Formation and Functional Significance of the Core–Belt Pattern of Neural Organization of Rostral Auditory Centers in Vertebrates
Belekhova, M. G., Kenigfest, N. B., & Chmykhova, N. M. (2020) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093020040018 · Cited by 4
Trial-by-trial fluctuations in amygdala activity track motivational enhancement of desirable sensory evidence during perceptual decision-making
Calabro, R., Lyu, Y., & Leong, Y. C. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac452 · Cited by 7
Organisation of afferents along the anterior-posterior and medial-lateral axes of the rat orbitofrontal cortexPreprint
Barreiros, I. V., Panayi, M. C., & Walton, M. E. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.28.272591 · Cited by 4
Chemogenetic inhibition of prefrontal projection neurons constrains top–down control of attention in young but not aged rats
Duggan, M. R., Joshi, S., Strupp, J., & Parikh, V. (2021) · Brain Structure and Function · doi:10.1007/s00429-021-02336-2 · Cited by 3
Inhibition of the basolateral amygdala to prelimbic cortex pathway enhances risk-taking during risky decision-making shock task in rats
Liu, N., Li, Y.-F., Zhao, X.-T., Li, Y., & Cui, R. (2025) · Physiology & Behavior · doi:10.1016/j.physbeh.2025.114819 · Cited by 3
Parallel neuronal structural plasticity with memory trace formation in the orbitofrontal cortex
Yount, S. T., Li, D. C., Stachowicz, K. M., Seo, E. H., Knight, K. A., Wiggins-Gamble, A., Allen, A. T., & Gourley, S. L. (2025) · Nature Communications · doi:10.1038/s41467-025-63542-8 · Cited by 3
Medial orbitofrontal cortical regulation of different aspects of Pavlovian and instrumental reward seeking
Jenni, N. L., Symonds, N. E., & Floresco, S. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06265-8 · Cited by 3
A Neural Mechanism of Cue-Outcome Expectancy Generated by the Interaction Between Orbitofrontal Cortex and Amygdala
Takei, K., Fujita, K., & Kashimori, Y. (2019) · Chemical Senses · doi:10.1093/chemse/bjz066 · Cited by 3
Sex-Specific Functional Connectivity in the Reward Network Related to Distinct Gender Roles
Du, Y., Wang, Y., Yu, M., Tian, X. S., & Liu, J. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2020.593787 · Cited by 4
Learning about reward identities and time
Delamater, A. R., Siegel, D. B., & Tu, N. (2023) · Behavioural Processes · doi:10.1016/j.beproc.2023.104859 · Cited by 3
Medial and lateral orbitofrontal cortices represent unique components of cognitive maps of task spacePreprint
Bradfield, L. A., & Hart, G. (2019) · doi:10.31234/osf.io/tk5gn · Cited by 3
Activation of Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Reward Seeking Triggered by Discriminative StimuliPreprint
LeCocq, M. R., Mainville-Berthiaume, A., Laplante, I., & Samaha, A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.11.617854 · Cited by 3
Orbitofrontal cortex spontaneously recovers latent information about outcomes upon devaluation
Hart, E. E., Bahena, L., & Schoenbaum, G. M. (2025) · Current Biology · doi:10.1016/j.cub.2025.07.083 · Cited by 2
The influence of nucleus accumbens shell D1 and D2 neurons on outcome-specific Pavlovian instrumental transferPreprint
Soegyono, O., Pépin, É., Leung, B. K., Chieng, B. C. H., Balleine, B. W., & Laurent, V. (2025) · eLife · doi:10.7554/elife.107566.4 · Cited by 3
Call for a more balanced approach to understanding orbital frontal cortex function.
Yalcinbas, E. A., Cazares, C., & Gremel, C. M. (2021) · Behavioral Neuroscience · doi:10.1037/bne0000450 · Cited by 2
The effect of emotional faces on reward-related probability learning in depressed patients
Gökçelli, D. K., Kizilates-Evin, G., Eroglu-Koc, S., Oğuz, K., Eraslan, C., Kitiş, Ö., & Gönül, A. S. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.247 · Cited by 2
Encoding of predictive associations in human prefrontal and medial temporal neurons during Pavlovian conditioningPreprint
Aquino, T. G., Courellis, H. S., Mamelak, A. N., Rutishauser, U., & O’Doherty, J. P. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.10.528055 · Cited by 2
Another look at the extinction of conditioned flavor preferences: Amount of training and tests for spontaneous recovery
Delamater, A. R., Tu, N., & Huang, J. (2021) · Learning & Behavior · doi:10.3758/s13420-021-00480-7 · Cited by 1
Serotonin transporter knockout in rats reduces beta- and gamma-band functional connectivity between the orbitofrontal cortex and amygdala during auditory discrimination
Boillot, M., ter Horst, J., López, J. R., Fazio, I. D., Steens, I. L. M., Cohen, M. X., & Homberg, J. R. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae334 · Cited by 1
Prefrontal modulation of striatal engagement: a hierarchical framework for goal-directed behavior
Kőszeghy, Á., & Passecker, J. (2026) · Communications Biology · doi:10.1038/s42003-026-10047-9 · Cited by 2
The oracle and the didact: Orbitofrontal influences on learning and dopaminergic error signaling
Schoenbaum, G. M., & Kahnt, T. (2026) · Neuron · doi:10.1016/j.neuron.2026.04.047 · Cited by 1
Identity-specific reward expectations in orbitofrontal cortex guide goal-directed choices
Witkowski, P. P., Henein, N., Moussa, N., Schoenbaum, G. M., & Kahnt, T. (2026) · PLoS Biology · doi:10.1371/journal.pbio.3003829 · Cited by 1
Amygdala and Cortex Relationships during Learning of a Sensory Discrimination Task
Levitan, D., & Gilad, A. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.0125-24.2024 · Cited by 3
Depressive cognitive style relates to an individual trait of time perception in bipolar depression: A preliminary study
Yoshiike, T., Melloni, E. M. T., Dallaspezia, S., Yamada, N., Kuriyama, K., & Benedetti, F. (2022) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2022.100363 · Cited by 1
Prefrontal cortex neural compensation during an operant devaluation taskPreprint
Fisher, H., Lin, H., May, J., McLean, C., & Pickens, C. L. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.08.18.456813 · Cited by 1
Neural Computations Underpinning Anxiety in Health and Disease
Walters, C. J. (2021) · University of Minnesota Digital Conservancy (University of Minnesota) · Cited by 1
Basolateral amygdala to insular cortex activity makes sign-tracking behavior insensitive to outcome valuePreprint
Keefer, S. E., Kochli, D. E., & Calu, D. J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.24.481881 · Cited by 1
Outcome-specific reward processing and decision-making
Kahnt, T. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-820480-1.00001-2 · Cited by 1
A Hippocampo-Cortical Pathway Detects Changes in the Validity of an Action as a Predictor of RewardPreprint
Piquet, R., Faugère, A., & Parkes, S. L. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4554595 · Cited by 1
The Role Of The Prelimbic, Infralimbic, And Cerebellar Cortices In Operant Behavior
Shipman, M. L. (2019) · ScholarWorks -A service of University of Vermont Libraries (University of Vermont)
Perceiving direct and averted gaze during emotion discrimination, affective empathy and affective theory of mind judgements: electrophysiological and behavioural effects
McCrackin, S. D. (2020) · UWSpace (University of Waterloo)
Optogenetic activation of basolateral amygdala projections to nucleus accumbens core promotes cue-induced expectation of reward but not instrumental pursuit of cuesPreprint
Servonnet, A., Rompré, P.-P., & Samaha, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.20.465037
Faculty Opinions recommendation of Chemogenetic manipulations of ventral tegmental area dopamine neurons reveal multifaceted roles in cocaine abuse.
Parker, L. A. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734452228.793560125
Neither Amphetamine nor Sub-Anesthetic Ketamine Treatment during Adolescence Impairs Devaluation in Rats Tested during Adulthood
Davis, I. R., Fisher, H., McLean, C., Murray, J., & Pickens, C. L. (2024) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2304083
Activating group II metabotropic glutamate receptors in the basolateral amygdala inhibits increases in reward seeking triggered by discriminative stimuli in rats
LeCocq, M. R., Mainville-Berthiaume, A., Laplante, I., & Samaha, A. (2025) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyaf030
The influence of nucleus accumbens shell D1 and D2 neurons on outcome-specific Pavlovian instrumental transferPreprint
Soegyono, O., Pépin, É., Leung, B. K., Chieng, B. C. H., Balleine, B. W., & Laurent, V. (2025) · eLife · doi:10.7554/elife.107566.1
The influence of nucleus accumbens shell D1 and D2 neurons on outcome-specific Pavlovian instrumental transferPreprint
Soegyono, O., Pépin, É., Leung, B. K., Chieng, B. C. H., Balleine, B. W., & Laurent, V. (2025) · eLife · doi:10.7554/elife.107566.2
The influence of nucleus accumbens shell D1 and D2 neurons on outcome-specific Pavlovian instrumental transferPreprint
Soegyono, O., Pépin, É., Leung, B. K., Chieng, B. C. H., Balleine, B. W., & Laurent, V. (2025) · eLife · doi:10.7554/elife.107566.3
PACAP neurons of the ventral dentate gyrus are not involved in fear acquisition in male PACAP-Cre micePreprint
Kamalı, O., Saka, H. B., Balcı, F., & Yavas, E. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6484651
Cortex préfrontal et flexibilité comportementale : implication de la noradrénaline
Cerpa, J.-C. (2019) · theses.fr (ABES) · doi:10.70675/d4f665b9z3943z4c88z9b4bzbf11cd7cf8d1
Perturbation des processus décisionnels : mise en évidence de vulnérabilités à la consommation de sucre ou d'édulcorants chez la souris
Hamelin, H. (2021) · theses.fr (ABES) · doi:10.70675/5e09cc1dz2ed2z449ez83b6zdb0777a4cd90
Functional characterization of Amygdala projections to motor related cortices during adaptive action-selection
Kouskoff, V. (2021) · theses.fr (ABES) · doi:10.70675/a8f4e479z2341z4f88zaf5bz91e7451d469d
Respiratory Adaption to Running Exercise : A Behavioral and Neuronal Circuits Study in Mice
Hérent, C. (2021) · doi:10.70675/d28bf017zb159z47c7z87fazcef8d994a841
Contribution of the rat insular cortex to stimulus-guided action
Tensaouti, Y. (2024) · theses.fr (ABES) · doi:10.70675/857ca5a2ze261z4e9bzb88dz744191d18105
Closed-loop model of mindfulness-based psychological regulation in competitive performance
Zhao, D. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1794689
Methamphetamine potentiates the use of outcome-specific associations via a hypothalamic-dopamine circuit
Hoang, I. B., Munier, J. J., Verghese, A., Taira, M., Abiero, A., Leake, J., Dawson, A., Wilcher, M. V. B., Ganesan, K., Ortega, M. E., et al. (2026) · Neuron · doi:10.1016/j.neuron.2026.05.008
Dopamine projections to the basolateral amygdala enable reward predictionPreprint
Ramírez-Armenta, K., Feng, C., Martinez, A., Andrade, J. E., Quach, J., Paredes, N., Sias, A. C., Griffin, N. K., Sharpe, M. J., & Wassum, K. M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.21.733629
Self-citation
Reward Memories Bias Instrumental Rule Selection via the Orbitofrontal-to-Secondary Motor cortex PathwayPreprint
Le, M., Milmoe, J., Nungesser, L., Maheras, A., & Keiflin, R. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.29.748039

Authors: Lichtenberg, N. T., Pennington, Z. T., Holley, S. M., Greenfield, V. Y., Cepeda, C., Levine, M. S., & Wassum, K. M.
Affiliations: University of California, Los Angeles (US)
ORCID: Lichtenberg, Nina T.
Pennington, Zachary T.
Holley, Sandra M.
Cepeda, Carlos
Levine, Michael S.
Wassum, Kate M.
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 2017-07-25
Volume: 37
Issue: 35
Pages: 8374-8384
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.0486-17.2017
PMC: PMC5577854
OpenAlex: W2736491203
Cited by: 171
References: 95
Citations by year: 2026: 9 · 2025: 13 · 2024: 14 · 2023: 13 · 2022: 18 · 2021: 37 · 2020: 22 · 2019: 24 · 2018: 18 · 2017: 3
FWCI: 10.51
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Neuroscience (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
eScholarship (California Digital Library) (submittedVersion)
eScholarship (California Digital Library) (submittedVersion, cc-by)
Funders: National Institutes of Health (DA024635)
University of California, Los Angeles
National Institute on Drug Abuse (T32DA024635, R01DA035443)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: basolateral amygdala, orbitofrontal cortex, reward anticipation, Pavlovian-to-instrumental transfer, decision-making, reward seeking, goal-directed behavior, monosynaptic connectivity
MeSH terms: Animals, Conditioning, Operant, Cues, Decision Making, Extinction, Psychological, Male, Motivation, Neural Pathways, Reward, Prefrontal Cortex, Rats, Long-Evans, Rats, Anticipation, Psychological, Basolateral Nuclear Complex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Basolateral Amygdala to Orbitofrontal Cortex Projections Enable Cue-Triggered Reward Expectations

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks