The DOI matches its Crossref record; 99 of the 99 references it cites were found in a registry or an index.
Quantitative Investigation of Connections of the Prefrontal Cortex in the Human and Macaque using Probabilistic Diffusion Tractography
Open accessAbstract
The functions of prefrontal cortex (PFC) areas are constrained by their anatomical connections. There is little quantitative information about human PFC connections, and, instead, our knowledge of primate PFC connections is derived from tracing studies in macaques. The connections of subcortical areas, in which white matter penetration and hence diffusion anisotropy are greatest, can be studied with diffusion-weighted imaging (DWI) tractography. We therefore used DWI tractography in four macaque and 10 human hemispheres to compare the connections of PFC regions with nine subcortical regions, including several fascicles and several subcortical nuclei. A distinct connection pattern was identified for each PFC and each subcortical region. Because some of the fascicles contained connections with posterior cortical areas, it was also possible to draw inferences about PFC connection patterns with posterior cortical areas. Notably, it was possible to identify similar circuits centered on comparable PFC regions in both species; PFC regions probably engage in similar patterns of regionally specific functional interaction with other brain areas in both species. In the case of one area traditionally assigned to the human PFC, the pars opercularis, the distribution of connections was not reminiscent of any macaque PFC region but, instead, resembled the pattern for macaque ventral premotor area. Some limitations to the DWI approach were apparent; the high diffusion anisotropy in the corpus callosum made it difficult to compare connection probability values in the adjacent cingulate region.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“The present results are also consistent with the proportions reported in Croxson et al. (2005).”
From Cortical Terminations of the Inferior Fronto-Occipital and Uncinate Fasciculi: Anatomical Stem-Based Virtual Dissection (2016) · cites this paper as Croxson et al. (2005)
The cited source says what the claim attributes to it.
In the citing paper
“These are consistent with the proportions reported in (Croxson et al., 2005) that used probabilistic tractography.”
From Cortical Terminations of the Inferior Fronto-Occipital and Uncinate Fasciculi: Anatomical Stem-Based Virtual Dissection (2016) · cites this paper as Croxson et al., 2005
In the citing paper
“Only preliminary data concerning the anatomical connectivity of ACC are available for the human brain (Croxson et al. 2005), and regional variations in connectivity between subregions of human ACC have not previously been investigated.”
From Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression (2008) · cites this paper as Croxson et al. 2005
In the citing paper
“Pathways traced in this way are reproducible (Heiervang et al. 2006) and generally reproduce those identified using postmortem dissection or tract tracing (Stieltjes et al. 2001; Croxson et al. 2005).”
From Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression (2008) · cites this paper as Croxson et al. 2005
In the citing paper
“However, the connections of sACC specifically have not previously been studied in the human brain, and the pathways running through the white matter region underlying sACC and targeted in DBS have not been established.”
From Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression (2008) · cites this paper as Croxson et al. 2005
In the citing paper
“Consistent with our current findings on the connectivity of sACC specifically, we previously found prominent connections between cingulate gyrus and amygdala, cingulum bundle, and NAC in both human and macaque (Croxson et al. 2005).”
From Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression (2008) · cites this paper as Croxson et al. 2005
In the citing paper
“Where these routes are known in the macaque, our results suggest the existence of similar pathways in the human brain (Cavada et al. 2000; Croxson et al. 2005; Schmahmann and Pandya 2006).”
From Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression (2008) · cites this paper as Croxson et al. 2005
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
Fast robust automated brain extraction
Smith, S. M. (2002) · Human Brain Mapping · doi:10.1002/hbm.10062 · Cited by 10,496
Zhang, Y., Brady, M., & Smith, S. M. (2001) · IEEE Transactions on Medical Imaging · doi:10.1109/42.906424 · Cited by 7,628
A global optimisation method for robust affine registration of brain images
Jenkinson, M., & Smith, S. M. (2001) · Medical Image Analysis · doi:10.1016/s1361-8415(01)00036-6 · Cited by 7,018
Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space
Collins, D. L., Neelin, P., Peters, T. M., & Evans, A. C. (1994) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199403000-00005 · Cited by 3,431 · cited 2×
“space (Talairach and Tournoux, 1988; Collins et al., 1994) defined the”
Characterization and propagation of uncertainty in diffusion-weighted MR imaging
Behrens, T. E. J., Woolrich, M. W., Jenkinson, M., Johansen‐Berg, H., Nunes, R. G., Clare, S., Matthews, P. M., Brady, J. M., & Smith, S. M. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10609 · Cited by 3,038
Self-citationCortical mechanisms of human imitation
Iacoboni, M., Woods, R. P., Brass, M., Bekkering, H., Mazziotta, J. C., & Rizzolatti, G. (1999) · Science · doi:10.1126/science.286.5449.2526 · Cited by 2,683
Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging
Behrens, T. E. J., Johansen-Berg, H., Woolrich, M. W., Smith, S. M., Wheeler-Kingshott, C. A. M., Boulby, P. A., Barker, G. J., Sillery, E. L., Sheehan, K., Ciccarelli, O., et al. (2003) · Nature Neuroscience · doi:10.1038/nn1075 · Cited by 2,330
Self-citationPrinciples of Frontal Lobe Function
Stuss, D. T. (2002) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195134971.001.0001 · Cited by 1,731
Primate anterior cingulate cortex: Where motor control, drive and cognition interface
Paus, T. (2001) · Nature Reviews Neuroscience · doi:10.1038/35077500 · Cited by 1,722 · cited 2×
“…of the CS, including the rostral cingulate motor zone and the tissue immediately anterior with which it is anatomically interconnected and functionally inter-related (Van Hoesen et al., 1993; Paus, 2001; Picard and Strick, 2001; Procyk and Joseph, 2001; Matsumoto et al., 2003; Walton et al., 2004).”
Background
Research works printed but not linked: 1
- 2003, Inf Process Med Imaging, 18, 684
Cited by
Sorted by citations
Items 401–411 of 411
Coenen, V. A., Rau, A., Watakabe, A., Skibbe, H., Yamamori, T., Schläpfer, T. E., Czornik, M., Meyer, D. M., Endres, D., Baldermann, J. C., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-8755074/v1
Albouy, P. (2013) · theses.fr (ABES) · doi:10.70675/3a2ec67ez135cz4270z9560z3076929a213f · Cited by 1
A closed loop framework of decision-making and learning in primate prefrontal circuits.
Nallapu, B. T. (2019) · theses.fr (ABES) · doi:10.70675/ec68f782z2b3ez44f3zb24fzeafa25ff668c · Cited by 1
Vision, Émotion et Santé Mentale : approche neuroscientifique de la dépression et de l'anxiété
Zorzi, L. D. (2019) · theses.fr (ABES) · doi:10.70675/948f4593z9cfez4024za02fz2d06c28a075e
Implication des dynamiques motrices dans la perception auditive
Zalta, A. (2022) · theses.fr (ABES) · doi:10.70675/2328afbbzf1ddz47d2z9376z80950d338df1
Specializations of human cerebral cortex
Preuss, T. M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-27380-3.00064-6
Grennan, G., Fang, A., Stocco, A., Bukhari, Q., Rangaprakash, D., Tadayonnejad, R., & Feusner, J. D. (2026) · Research Square · doi:10.21203/rs.3.rs-10780500/v1
Metadata
- Authors
- Croxson, P. L., Johansen-Berg, H., Behrens, T. E. J., Robson, M. D., Pinsk, M. A., Gross, C. G., Richter, W., Richter, M. C., Kastner, S., & Rushworth, M. F. S.
- Affiliations
- John Radcliffe Hospital (GB)
- University of Oxford (GB)
- Princeton University (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2005-09-28
- Volume
- 25
- Issue
- 39
- Pages
- 8854-8866
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6725599
- OpenAlex
- W2030183678
- Cited by
- 410
- References
- 99
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 7 · 2023: 10 · 2022: 9 · 2021: 15 · 2020: 18 · 2019: 21 · 2018: 20 · 2017: 14 · 2016: 19 · 2015: 34 · 2014: 32 · 2013: 31 · 2012: 25
- FWCI
- 12.74
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust
- National Institutes of Health
- Medical Research Council
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- prefrontal cortex, white matter connections, diffusion-weighted imaging, macaque, human brain, subcortical nuclei, corpus callosum, cingulate cortex, pars opercularis, cross-species comparison
- MeSH terms
- Adult, Animals, Brain Mapping, Female, Humans, Macaca fascicularis, Male, Neural Pathways, Prefrontal Cortex, Diffusion Magnetic Resonance Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
