The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines
Open accessAbstract
Reactive astrogliosis is a characteristic response of astrocytes to inflammation and trauma of the adult CNS. To assess the hypothesis that cytokines from inflammatory mononuclear cells that accumulate around lesion sites have a role in modulating astrogliosis, this study sought to take advantage of the neonatal system in which astrogliosis is reported to be minimal following injury and in which the immune system is relatively immature compared to adult animals. A nitrocellulose membrane implant into the cortex of postnatal day 3 mice resulted in a tremendous astrogliotic response 4 d later, as measured by glial fibrillary acidic protein (GFAP) immunoreactivity and GFAP content. In contrast, a neonatal stab wound produced limited astroglial response when compared to the adult stab wound. Utilizing the neonatal stab wound model, cytokines were microinjected into the wound site at the time of injury. All cytokines tested (gamma-IFN, IL-1, IL-2, IL-6, TNF- alpha, and M-CSF) resulted in a significantly increased astrogliosis. The specificity of the cytokine response was demonstrated by the inability of human gamma-IFN, but not mouse gamma-IFN, in enhancing neonatal mouse astrogliosis, in accordance with reports that the interaction of gamma-IFN with its receptor occurs in a species-specific manner. We conclude that neonatal astrocytes can become reactive if an adequate injury stimulus is presented, and that the release of immunoregulatory cytokines by cells around lesion sites may be a mechanism that contributes to the production of gliosis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It has been shown to support proliferation of both astrocytes and microglia [151, 152] and enhance microglial phagocytosis [153, 154].”
From Glial contributions to neurodegeneration in tauopathies (2017) · cites this paper as [152]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
McKeon, R., Schreiber, R., Rudge, J., & Silver, J. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-11-03398.1991 · Cited by 1,188
Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury
Giulian, D., & Lachman, L. B. (1985) · Science · doi:10.1126/science.3872478 · Cited by 847
Eng, L. F. (1985) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(85)80063-1 · Cited by 737
Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization
Giulian, D., Woodward, J., Young, D., Krebs, J., & Lachman, L. B. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-07-02485.1988 · Cited by 583
Woodroofe, M. N., Sarna, G. S., Wadhwa, M., Hayes, G. M., Loughlin, J., Tinker, A., & Cuzner, M. L. (1991) · Journal of Neuroimmunology · doi:10.1016/0165-5728(91)90110-s · Cited by 580
Quantitative aspects of reactive gliosis: A review
Norton, W. T., Aquino, D. A., Hozumi, I., Chiu, F., & Brosnan, C. F. (1992) · Neurochemical Research · doi:10.1007/bf00993263 · Cited by 549
Selmaj, K. W., Farooq, M., Norton, W. T., Raine, C. S., & Brosnan, C. F. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.144.1.129 · Cited by 544
Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion
Taupin, V., Toulmond, S., Serrano, A., Bénavidès, J., & Zavala, F. (1993) · Journal of Neuroimmunology · doi:10.1016/0165-5728(93)90008-m · Cited by 512
The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain
Giulian, D., Chen, J., Ingeman, J., George, J., & Noponen, M. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-12-04416.1989 · Cited by 498
Bignami, A., & Dahl, D. R. (1974) · The Journal of Comparative Neurology · doi:10.1002/cne.901530104 · Cited by 491
Cited by
Sorted by citations
Items 201–300 of 340
Curcumin – vom Molekül zur biologischen Wirkung
Esatbeyoglu, T., Huebbe, P., Ernst, I. M. A., Chin, D., Wagner, A. E., & Rimbach, G. H. (2012) · Angewandte Chemie · doi:10.1002/ange.201107724 · Cited by 30
Regulation of the Heparan Sulfate Proteoglycan, Perlecan, by Injury and Interleukin‐1α
de Yebenes, E. G., Ho, A., Damani, T., Fillit, H. M., & Blum, M. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0730812.x · Cited by 30
Gliomatosis Peritonei Combined with Mature Ovarian Teratoma Immunohistochemical Observations
Gocht, A., Löhler, J., Scheidel, P. H., Stegner, H.-E., & Saeger, W. (1995) · Pathology - Research and Practice · doi:10.1016/s0344-0338(11)80603-5 · Cited by 30
Safieh‐Garabedian, B., Ochoa‐Chaar, C. I., Poole, S., Massaad, C. A., Atweh, S., Jabbur, S. J., & Saadé, N. E. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00500-1 · Cited by 29
Signal transduction pathways in oligodendrocytes: Role of tumor necrosis factor‐α
Soliven, B. C., & Szuchet, S. (1995) · International Journal of Developmental Neuroscience · doi:10.1016/0736-5748(95)00019-d · Cited by 29
Zhang, S., Li, W., Wang, W., Zhang, S. S.-M., Huang, P. C., & Zhang, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055683 · Cited by 28
Suramin disrupts the gliotic response following a stab wound injury to the adult rat brain
Prospero, N. A. D., Zhou, X.-R., Meiners, S. A., McAuliffe, W. G., Ho, S.-Y., & Geller, H. M. (1998) · Journal of Neurocytology · doi:10.1023/a:1006995624754 · Cited by 28
Olopade, J. O., Fatola, I. O., & Olopade, F. E. (2011) · PubMed · Cited by 27
Teo, J. D., Morris, M. J., & Jones, N. M. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.10.010 · Cited by 28
Chu, J. M. T., Xiong, W., Linghu, K., Liu, Y., Zhang, Y., Zhao, G. D., Irwin, M. G., Wong, G. T. C., & Yu, H. (2018) · Experimental Neurobiology · doi:10.5607/en.2018.27.6.564 · Cited by 27
Anti-inflammatory substances – a new therapeutic option in Alzheimer's disease
Hüll, M. (1999) · Drug Discovery Today · doi:10.1016/s1359-6446(99)01339-2 · Cited by 27
柴山, 美., Kuchiwaki, H., INAO, S., Yoshida, K., & Ito, M. (1996) · Journal of Neurotrauma · doi:10.1089/neu.1996.13.801 · Cited by 25
Fang, M., Sun, Y., Hu, Z., Yang, J., Davies, H., Wang, B., Ling, S., & Han, S. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.01.010 · Cited by 24
Gabryel, B., Łabuzek, K., Małecki, A., & Herman, Z. S. (2004) · PubMed · Cited by 24
Fang, M., He, D., Zhang, F., Hu, Z., Yang, J., Jiang, H., & Han, S. (2013) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2013.00044 · Cited by 23
Yuan, T., & Yu, H. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22229 · Cited by 23
Dose-Dependent Anti-Inflammatory and Neuroprotective Effects of an α ν β 3 Integrin-Binding Peptide
Han, S., Zhang, F., Hu, Z., Sun, Y., Yang, J., Davies, H., Yew, D. T. W., & Fang, M. (2013) · Mediators of Inflammation · doi:10.1155/2013/268486 · Cited by 23
Potential roles for tumor necrosis factor and nuclear factor‐κB in seizure activity
Albensi, B. C. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1206 · Cited by 23
TNFα reduces glutamate induced intracellular Ca2+ increase in cultured cortical astrocytes
Köller, H., Trimborn, M., von Giesen, H.-J., Schroeter, M., & Arendt, G. (2001) · Brain Research · doi:10.1016/s0006-8993(00)03318-7 · Cited by 23
Saraswat, D., Welliver, R. R., Ravichandar, R., Tripathi, A. K., Polanco, J. J., Broome, J. E., Hurley, E. L., Dutta, R., Feltri, M. L., & Sim, F. J. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0580-20.2021 · Cited by 24
Immuno-characterisation of neuroendocrine cells of the rat thymus gland in vitro and in vivo
Botham, C. A., Jones, G. V., & Kendall, M. D. (2001) · Cell and Tissue Research · doi:10.1007/s004410000185 · Cited by 22
Emerging Roles of Microglia in Neuro-vascular Unit: Implications of Microglia-Neurons Interactions
Ding, Z., Guo, S., Luo, L., Zheng, Y., Gan, S., Kang, X., Wu, X., & Zhu, S. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.706025 · Cited by 23
Role of Thymulin or Its Analogue as a New Analgesic Molecule
Dardenne, M., Saadé, N. E., & Safieh‐Garabedian, B. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1366.006 · Cited by 21
Liu, W., Xu, G., Jiang, C., & Da, C. (2009) · Current Eye Research · doi:10.1080/02713680802650369 · Cited by 20
Mirowska-Guzel, D., Kurowska, K., Skierski, J., Koronkiewicz, M., Wicha, W., Kruszewska, J., Członkowski, A., & Członkowska, A. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.03.024 · Cited by 17
Cellular Responses to Penetrating CNS Injury
Berry, M., Butt, A. M., & Logan, A. (1998) · CRC Press eBooks · doi:10.1201/9781420048544.ch1 · Cited by 20
Penkowa, M., Poulsen, C. B., Carrasco, J., & Hidalgo, J. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.7968 · Cited by 20
RetractedAstrocytes: Initiators of and Responders to Inflammation
Soung, A., & Klein, R. S. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.89760 · Cited by 19
P2Y receptors on astrocytes and microglia mediate opposite effects in astroglial proliferation
Quintas, C., Fraga, S., Gonçalves, J., & Queiróz, G. (2011) · Purinergic Signalling · doi:10.1007/s11302-011-9235-x · Cited by 18
TSPO regulation in reactive gliotic diseases
McNeela, A. M., Bernick, C. B., Hines, R. M., & Hines, D. J. (2018) · Journal of Neuroscience Research · doi:10.1002/jnr.24212 · Cited by 22
Wang, Y., & Zhou, C.-F. (2004) · Glia · doi:10.1002/glia.20152 · Cited by 18
Glial reaction and reactive glia
Kálmán, M. (2003) · Advances in molecular and cell biology · doi:10.1016/s1569-2558(03)31035-5 · Cited by 17
Moxon, K. A., Hallman, S. J., Sundarakrishnan, A., Wheatley, M. A., Nissanov, J., & Barbee, K. A. (2009) · Materials · doi:10.3390/ma2041762 · Cited by 16
Hutson, L. W., Lebonville, C. L., Jones, M., Fuchs, R. A., & Lysle, D. T. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.01.017 · Cited by 17
Plata‐Saláman, C. R. (2002) · Acta Neuropsychiatrica · doi:10.1034/j.1601-5215.2002.140602.x · Cited by 17
Microglia as a Source and Target of Cytokine Activities in the Brain
Hanisch, U. (2002) · Springer eBooks · doi:10.1007/978-1-4757-4139-1_5 · Cited by 17
Role of inflammation and cellular stress in brain injury and central nervous system diseases
Barone, F. C., & Kilgore, K. S. (2006) · Clinical Neuroscience Research · doi:10.1016/j.cnr.2006.09.010 · Cited by 17
Rupture très prématurée des membranes: physiopathologie des conséquences neurologiques
Baud, O., Fontaine, R. H., Olivier, P., Maury, L., Moussawi, F. E., Bauvin, I., Arsac, M., Hovhannisyan, S., Farnoux, C., & Aujard, Y. (2007) · Archives de Pédiatrie · doi:10.1016/s0929-693x(07)80011-x · Cited by 17
Peković, S., Filipovic, R., Subasic, S., Lavrnja, I. C., Savić, D. Z., Nedeljković, N., Rakić, L., & Stojiljković, M. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1342.027 · Cited by 17
Norenberg, M. D. (2004) · CRC Press eBooks · doi:10.1201/9781420039740.ch5 · Cited by 17
Immune and non-immune actions of interferon-β-1b on primary human neural cells
McLaurin, J., Antel, J. P., & Yong, V. W. (1995) · Multiple Sclerosis Journal · doi:10.1177/135245859500100103 · Cited by 17
Self-citationAmyloid precursor protein truncated at any of the ?-secretase sites is not cleaved to ?-amyloid
Paganetti, P., Lis, M., Klafki, H.-W., & Staufenbiel, M. (1996) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19961101)46:3 · Cited by 39
Support of axonal regrowth by endogenous mechanisms following spinal cord injury in adult rats
West, N. R., Kuo-LeBlanc, V., & Collins, G. H. (2001) · Neuropathology · doi:10.1046/j.1440-1789.2001.00398.x · Cited by 16
Designing a Brain-Machine Interface for Neuroprosthetic Control
Moxon, K. A. (2000) · doi:10.1201/9781420039054-13 · Cited by 16
Wang, Q., Ishikawa, T., Michiue, T., Zhu, B.-L., & Maeda, H. (2011) · Forensic Science International · doi:10.1016/j.forsciint.2011.03.037 · Cited by 15
Peterson, K. E., Hughes, S., Dimcheff, D. E., Wehrly, K., & Chesebro, B. W. (2004) · Journal of Virology · doi:10.1128/jvi.78.23.13104-13112.2004 · Cited by 15
The astrocyte response to neural injury: a review and reconsideration of key features
O’Callaghan, A. R. L. A. J. P. (2002) · CRC Press eBooks · doi:10.1201/9780203219096-23 · Cited by 15
Failure Modes of Implanted Neural Interfaces
Delbeke, J., Haesler, S., & Prodanov, D. (2020) · Springer eBooks · doi:10.1007/978-3-030-41854-0_6 · Cited by 16
Kim, K.-J., Shin, M., Cho, H.-S., & Kim, Y.-P. (2014) · Journal of Exercise Rehabilitation · doi:10.12965/jer.140084 · Cited by 14
Reactive astrocytes increase the expression of P‑gp and Mrp1 via TNF‑α and NF‑κB signaling
Wang, Y., Huang, S., Jiang, Y., Liu, Y., Song, T., Li, D., & Yang, L. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7939 · Cited by 14
Wang, Y., Zhu, N., Wang, K., Zhang, Z., & Wang, Y. (2012) · PubMed Central · doi:10.3969/j.issn.1673-5374.2012.22.005 · Cited by 13
Röhl, C., Held‐Feindt, J., & Sievers, J. (2003) · Developmental Brain Research · doi:10.1016/s0165-3806(03)00171-8 · Cited by 13
Mechanisms of neuronal cell death
Morrison, R. S., Kinoshita, Y., Xiang, H., Johnson, M. D., Kuntz, C., Ghatan, S., Ho, J. T., & Schwartzkroin, P. A. (1998) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/(sici)1098-2779(1998)4:3 · Cited by 15
Self-citationAstrocyte-Neuron Interactions in Spinal Cord Injury
Reyes, C., & Mokalled, M. H. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-64839-7_9 · Cited by 13
Liu, Q., Tan, Y., Zhang, Z., Tang, W., Han, L., Peng, K., Liu, M., & Tian, G. (2025) · Inflammation Research · doi:10.1007/s00011-024-01984-4 · Cited by 12
Marcondes, M. C. G., Furtado, G. C., Wensky, A. K., de Lafaille, M. A. C., Fox, H. S., & Lafaille, J. J. (2005) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)62485-6 · Cited by 12
Reactive Astrogliosis in the Injured and Postischemic Brain
Jabs, R., Bekar, L. K., & Walz, W. (1999) · Humana Press eBooks · doi:10.1007/978-1-59259-479-5_9 · Cited by 12
Zhang, Y., Kong, Q., Fan, J., & Zhao, H. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107658 · Cited by 14
Bruno, C. J., Greco, T. M., & Ischiropoulos, H. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.04.041 · Cited by 11
Espírito‐Santo, S., Mendonça, H. R., Menezes, G. D., Goulart, V. G., Gomes, A. L. T., Marra, C., Faria‐Melibeu, A. D. C., Serfaty, C. A., Sholl‐Franco, A., & Campello‐Costa, P. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.10.034 · Cited by 11
Erythrina abyssinica prevents meningoencephalitis in chronic Trypanosoma brucei brucei mouse model
Nasimolo, J., Kiama, S. G., Gathumbi, P. K., Makanya, A. N., & Kagira, J. M. (2014) · Metabolic Brain Disease · doi:10.1007/s11011-014-9488-5 · Cited by 11
Ceresoli, G., Fuller, M. S., & Schwarcz, R. M. (1996) · Developmental Brain Research · doi:10.1016/0165-3806(95)00200-6 · Cited by 11
Lipopolysaccharide enhances synthesis of brain-derived neurotrophic factor in cultured rat microglia
Miwa, T., Furukawa, S., Nakajima, K., Furukawa, Y., & Kohsaka, S. (1997) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19971215)50:6 · Cited by 181
Ren, Z., Zhang, C.-X., Zheng, Y., Chen, C.-A., Dan-Chen, Lan, X., Yan, X., Liu, Y., He, Y.-H., Cheng, J.-L., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156696 · Cited by 10
Lau, W. K. W., Mak, J., Chan, K., & Law, A. (2011) · Neurotoxicity research · doi:10.1007/s12640-011-9301-8 · Cited by 11
Cloutier, F., Sears‐Kraxberger, I., Keachie, K., & Keirstead, H. S. (2013) · Clinical and Developmental Immunology · doi:10.1155/2013/812456 · Cited by 11
Kumaraswamy, G. K., Fu, M., & Docherty, J. J. (2006) · Journal of NeuroVirology · doi:10.1080/13550280600970417 · Cited by 10
Macroglial alterations after isolated optic nerve sheath fenestration in rabbit.
Villain, M., Sandillon, F., Müller, A., Candon, E., Alonso, G., Arnaud, B., & Privat, A. (2002) · PubMed · Cited by 9
Ajtai, B. M., Kállai, L., & Kálmán, M. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6496 · Cited by 9
Designing a Brain-Machine Interface for Neuroprosthetic Control
Moxon, K. A., Morizio, J., Chapin, J. K., Nicolelis, M. A. L., & Wolf, P. (2000) · Frontiers in neuroscience · doi:10.1201/9781420039054.pt2 · Cited by 9
Tejada‐Berges, T., & Yong, V. W. (1994) · Brain Research · doi:10.1016/0006-8993(94)90404-9 · Cited by 9
Self-citationEffect of Interleukin‐1β on the Expression of Actin Isoforms in Cultured Mouse Astroglia
Abd‐El‐Basset, E. M., & Abd‐El‐Barr, M. M. (2010) · The Anatomical Record · doi:10.1002/ar.21303 · Cited by 8
Role of glial filaments in cells and tumors of glial origin: a review
Rutka, J. T., Murakami, M., Dirks, P. B., Hubbard, S. L., Becker, L. E., Fukuyama, K., Jung, S., & Matsuzawa, K. (1997) · Neurosurgical FOCUS · doi:10.3171/foc.1997.3.1.2 · Cited by 8
Zamani, N., Osgoei, L. T., Aliaghaei, A., Zamani, N., & Hassanian‐Moghaddam, H. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-01108-z · Cited by 7
Comparative aspects of microglia reaction in white and gray matter.
Cătălin, B., Mitran, S. I., Albu, C. V., & Iancău, M. (2013) · Europe PMC (PubMed Central) · Cited by 7
Petit, A., Quenneville, N., Vallée, A., Pierret, P., & Doucet, G. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.7954 · Cited by 7
GFAP expression induced by dopamine D2 receptor agonists in the rat pituitary intermediate lobe
Sands, S. A., & Chronwall, B. M. (1996) · Endocrine · doi:10.1007/bf02738872 · Cited by 7
Is there a role for NK cells in the pathogenesis of multiple sclerosis? A case study
Filaci, G., Bacchetta, R., & Zanetti, M. (1999) · Human Immunology · doi:10.1016/s0198-8859(98)00121-9 · Cited by 6
Zubareva, O. E., & Клименко, В. М. (2013) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-013-9767-3 · Cited by 6
Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system
Fawcett, J. W. (1997) · Springer eBooks · doi:10.1007/978-3-642-60905-3_24 · Cited by 6
Barone, F. C. (1998) · Emerging Therapeutic Targets · doi:10.1517/14728222.2.2.17 · Cited by 6
Walsh, C. M., Colbert, R., Reynolds, J. R., Dunne, E., Aiyegbusi, E. D., O'Carroll, R., Wychowaniec, J. K., Masuda, T., Knobeloch, K., Prinz, M., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.07.018 · Cited by 6
Wang, Q., Michiue, T., & Mae, H. (2012) · InTech eBooks · doi:10.5772/50225 · Cited by 5
Chappus-McCendie, H., Poulin, M.-A., Chouinard‐Watkins, R., Vandal, M., Calon, F., Lauzon, M.-A., & Plourde, M. (2022) · Aging Brain · doi:10.1016/j.nbas.2022.100046 · Cited by 5
González, P., Peluffo, H., Acarín, L., Villaverde, A., González, B., & Castellano, B. (2011) · Journal of Neuroscience Research · doi:10.1002/jnr.22741 · Cited by 5
Ziaja, M., Pyka, J., Ciombor, J., & Plonka, P. M. (2005) · Jagiellonian University Repository (Jagiellonian University) · Cited by 5
[14] Cytokines as mediators of reactive astrogliosis
Yong, V. W., & Balasingam, V. (1995) · Methods in neurosciences · doi:10.1016/s1043-9471(06)80152-7 · Cited by 5
Self-citationPawliński, R., Setkowicz, Z., Małodzińska, K., & Janeczko, K. J. (1999) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-1999-1311 · Cited by 4
Menezes, G. D., Goulart, V. G., Espírito‐Santo, S., Oliveira-Silva, P., Serfaty, C. A., & Campello‐Costa, P. (2016) · NeuroImmunoModulation · doi:10.1159/000444529 · Cited by 4
Glial Response to Excitotoxic Injury in the Immature Rat Brain
Acarín, L., González, B., Castro, A. J., & Castellano, B. (1998) · Springer eBooks · doi:10.1007/978-1-4615-5737-1_15 · Cited by 4
Pawliński, R., & Janeczko, K. J. (1997) · Brain Research · doi:10.1016/s0006-8993(97)01024-x · Cited by 4
Mitogen-Activated Protein Kinase Pathways Following Traumatic Brain Injury
Otani, N., Nawashiro, H., Nagatani, K., Takeuchi, S., Kobayashi, H., & Shima, K. (2011) · Neuroscience & Medicine · doi:10.4236/nm.2011.23028 · Cited by 3
Zhang, Z., Zhao, W. G., Gu, P., Zhou, Y., Wu, R., Zhou, L., Cui, Q., Chen, H., Zhang, L., Zhang, K., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1663711/v1 · Cited by 3
Role of the inflammatory process in traumatic brain damage
Morganti-Kossmann, C., Satgunaseelan, L., Bye, N., Nguyen, P. N., & Kossmann, T. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9781139195805.015 · Cited by 2
Inflammation and Potential Anti-Inflammatory Approaches in Stroke
Koıstınaho, J., & Yrjänheikki, J. (2003) · Humana Press eBooks · doi:10.1007/978-1-59259-297-5_9 · Cited by 2
Gliosis Growth Factors in the Adult and Aging Rat Brain
Labourdette, G., & Eclancher, F. (2002) · Humana Press eBooks · doi:10.1007/978-1-59259-105-3_9 · Cited by 2
Herrera, F., Maher, P. A., & Schubert, D. A. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.02.011 · Cited by 1
Correale, J. D., & Gaitán, M. I. (2019) · Contemporary clinical neuroscience · doi:10.1007/978-3-030-19515-1_10 · Cited by 1
İskemik Beyin Hasarında Reaktif Astrositlerin Fonksiyonları
Akbulut, N. H., Topal, G., & Eyigör, Ö. (2023) · Uludağ Üniversitesi Tıp Fakültesi Dergisi · doi:10.32708/uutfd.1261257 · Cited by 3
Astrocytes Functions and Their Involvement in Brain Injury
Hamdan, Y. A., Rhazi, M., El‐Mansoury, B., Kabdy, H., Oukhrib, M., Aitbaba, A., Housseini, A. E., Ahmad, Z. H., & Oudadesse, H. (2023) · Advances in bioinformatics and biomedical engineering book series · doi:10.4018/978-1-6684-9675-6.ch008 · Cited by 1
Metadata
- Authors
- Balasingam, V, Tejada-Berges, T., Wright, E., Bouckova, R., & Yong, V.
- Affiliations
- McGill University (CA)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 1994-02-01
- Volume
- 14
- Issue
- 2
- Pages
- 846-856
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6576825
- OpenAlex
- W2158406932
- Cited by
- 342
- References
- 63
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 3 · 2023: 6 · 2022: 4 · 2021: 6 · 2020: 6 · 2019: 7 · 2018: 7 · 2017: 8 · 2016: 5 · 2015: 6 · 2014: 6 · 2013: 14 · 2012: 7
- FWCI
- 13.60
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Government of Canada
- Medical Research Council Canada
- Medical Research Council
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Clinical Neurology › Spinal Cord Injury Research
- Keywords
- reactive astrogliosis, neonatal brain, cytokines, astrocytes, stab wounds, glial fibrillary acidic protein, interferon-gamma, neuroinflammation, neonatal mice
- MeSH terms
- Animals, Animals, Newborn, Astrocytes, Brain, Brain Injuries, Cell Division, DNA, Female, Glial Fibrillary Acidic Protein, Humans, Inflammation, Interferon-gamma, Interleukin-1, Interleukin-2, Male, Mice, Inbred Strains, Microinjections, Recombinant Proteins, Thymidine, Time Factors, Tumor Necrosis Factor-alpha, Wounds, Stab, Biomarkers, Interleukin-6, Macrophage Colony-Stimulating Factor, Cytokines, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review