The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines
Open accessAbstract
Reactive astrogliosis is a characteristic response of astrocytes to inflammation and trauma of the adult CNS. To assess the hypothesis that cytokines from inflammatory mononuclear cells that accumulate around lesion sites have a role in modulating astrogliosis, this study sought to take advantage of the neonatal system in which astrogliosis is reported to be minimal following injury and in which the immune system is relatively immature compared to adult animals. A nitrocellulose membrane implant into the cortex of postnatal day 3 mice resulted in a tremendous astrogliotic response 4 d later, as measured by glial fibrillary acidic protein (GFAP) immunoreactivity and GFAP content. In contrast, a neonatal stab wound produced limited astroglial response when compared to the adult stab wound. Utilizing the neonatal stab wound model, cytokines were microinjected into the wound site at the time of injury. All cytokines tested (gamma-IFN, IL-1, IL-2, IL-6, TNF- alpha, and M-CSF) resulted in a significantly increased astrogliosis. The specificity of the cytokine response was demonstrated by the inability of human gamma-IFN, but not mouse gamma-IFN, in enhancing neonatal mouse astrogliosis, in accordance with reports that the interaction of gamma-IFN with its receptor occurs in a species-specific manner. We conclude that neonatal astrocytes can become reactive if an adequate injury stimulus is presented, and that the release of immunoregulatory cytokines by cells around lesion sites may be a mechanism that contributes to the production of gliosis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It has been shown to support proliferation of both astrocytes and microglia [151, 152] and enhance microglial phagocytosis [153, 154].”
From Glial contributions to neurodegeneration in tauopathies (2017) · cites this paper as [152]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
McKeon, R., Schreiber, R., Rudge, J., & Silver, J. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-11-03398.1991 · Cited by 1,188
Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury
Giulian, D., & Lachman, L. B. (1985) · Science · doi:10.1126/science.3872478 · Cited by 847
Eng, L. F. (1985) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(85)80063-1 · Cited by 737
Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization
Giulian, D., Woodward, J., Young, D., Krebs, J., & Lachman, L. B. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-07-02485.1988 · Cited by 583
Woodroofe, M. N., Sarna, G. S., Wadhwa, M., Hayes, G. M., Loughlin, J., Tinker, A., & Cuzner, M. L. (1991) · Journal of Neuroimmunology · doi:10.1016/0165-5728(91)90110-s · Cited by 580
Quantitative aspects of reactive gliosis: A review
Norton, W. T., Aquino, D. A., Hozumi, I., Chiu, F., & Brosnan, C. F. (1992) · Neurochemical Research · doi:10.1007/bf00993263 · Cited by 549
Selmaj, K. W., Farooq, M., Norton, W. T., Raine, C. S., & Brosnan, C. F. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.144.1.129 · Cited by 544
Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion
Taupin, V., Toulmond, S., Serrano, A., Bénavidès, J., & Zavala, F. (1993) · Journal of Neuroimmunology · doi:10.1016/0165-5728(93)90008-m · Cited by 512
The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain
Giulian, D., Chen, J., Ingeman, J., George, J., & Noponen, M. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-12-04416.1989 · Cited by 498
Bignami, A., & Dahl, D. R. (1974) · The Journal of Comparative Neurology · doi:10.1002/cne.901530104 · Cited by 491
Cited by
Sorted by citations
Items 101–200 of 340
Interferon‐γ Expression in Periventricular Leukomalacia in the Human Brain
Folkerth, R. D., Keefe, R. J., Haynes, R. L., Trachtenberg, F. L., Volpe, J. J., & Kinney, H. C. (2004) · Brain Pathology · doi:10.1111/j.1750-3639.2004.tb00063.x · Cited by 102
Role of IL-6 and the Soluble IL-6 Receptor in Inhibition of VCAM-1 Gene Expression
Oh, J., Wagoner, N. J. V., Rose‐John, S., & Benveniste, E. N. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.9.4992 · Cited by 102
Little, A. R., Benkovic, S. A., Miller, D. B., & O'Callaghan, J. P. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00359-7 · Cited by 99
The effect of activated microglia on astrogliosis parameters in astrocyte cultures
Röhl, C., Lucius, R., & Sievers, J. (2007) · Brain Research · doi:10.1016/j.brainres.2006.10.057 · Cited by 98
Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system
Fawcett, J. W. (1997) · Cell and Tissue Research · doi:10.1007/s004410050943 · Cited by 97
Paintlia, M. K., Paintlia, A. S., Contreras, M. A., Singh, I., & Singh, A. K. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2007.12.011 · Cited by 93
Destruction and reconstruction: Hypoxia and the developing brain
Barrett, R. D., Bennet, L., Davidson, J. O., Dean, J. M., George, S. A., Emerald, B. S., & Gunn, A. J. (2007) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.20095 · Cited by 89
Enhancement of immunoreactivity for NF-κB in human cerebral infarctions
Terai, K., Matsuo, A., McGeer, E. G., & McGeer, P. L. (1996) · Brain Research · doi:10.1016/s0006-8993(96)01073-6 · Cited by 86
Astrocyte loss and astrogliosis in neuroinflammatory disorders
Hostenbach, S., Cambron, M., D’haeseleer, M., Kooijman, R., & Keyser, J. D. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.10.012 · Cited by 87
Huleihel, M., Golan, H. M., & Hallak, M. (2004) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-2-17 · Cited by 86
Copelman, C. A., Cuzner, M. L., Groome, N. P., & Diemel, L. T. (2000) · Glia · doi:10.1002/(sici)1098-1136(200006)30:4 · Cited by 35
Sticozzi, C., Belmonte, G., Meini, A., Carbotti, P., Grasso, G., & Palmi, M. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.07.061 · Cited by 85
The Potential Role of Vascular Endothelial Growth Factor in the Central Nervous System
Yasuhara, T., Shingo, T., & Date, I. (2004) · Reviews in the Neurosciences · doi:10.1515/revneuro.2004.15.4.293 · Cited by 85
Wu, J.-P., Kuo, J., Liu, Y.-L., & Tzeng, S. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01472-5 · Cited by 84
Maternal infection-induced white matter injury is reduced by treatment with interleukin-10
Rodts‐Palenik, S., Wyatt‐Ashmead, J., Pang, Y., Thigpen, B. D., Cai, Z., Rhodes, P. G., Martin, J. N., Jr., Granger, J. P., & Bennett, W. A. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.06.093 · Cited by 83
Expression of ??-synuclein in a human glioma cell line and its up-regulation by interleukin-1??
Tanji, K., Imaizumi, T., Yoshida, H., Mori, F., Yoshimoto, M., Satoh, K., & Wakabayashi, K. (2001) · Neuroreport · doi:10.1097/00001756-200107030-00028 · Cited by 81
Therapeutic potential of anti-inflammatory drugs in focal stroke
Barone, F. C., & Parsons, A. A. (2000) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.9.10.2281 · Cited by 80
Tian, D., Dong, Q., Pan, D., He, Y. J., Yu, Z., Xie, M.-J., & Wang, W. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.005 · Cited by 80
αVβ3 Integrin regulates astrocyte reactivity
Lagos‐Cabré, R., Álvarez, Á., Kong, M., Burgos‐Bravo, F., Cárdenas, A., Rojas-Mancilla, E., Pérez-Núñez, R., Herrera‐Molina, R., Rojas, F., Schneider, P., et al. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-017-0968-5 · Cited by 81
Acarín, L., González, B., Hidalgo, J., Castro, A. J., & Castellano, B. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00022-6 · Cited by 79
Onoda, A., Takeda, K., & Umezawa, M. (2017) · Particle and Fibre Toxicology · doi:10.1186/s12989-017-0184-6 · Cited by 77
Does Interleukin-6 Genotype Influence Cerebral Injury or Developmental Progress After Preterm Birth?
Harding, D. R., Dhamrait, S., Whitelaw, A., Humphries, S. E., Marlow, N., & Montgomery, H. (2004) · PEDIATRICS · doi:10.1542/peds.2003-0494-f · Cited by 76
Molecular Strategies in CNS Injury
Yakovlev, A. G., & Faden, A. I. (1995) · Journal of Neurotrauma · doi:10.1089/neu.1995.12.767 · Cited by 74
Inflammatory Response Following Diffuse Axonal Injury
Yu, L., & Wen, L. (2013) · International Journal of Medical Sciences · doi:10.7150/ijms.5423 · Cited by 72
Golovina, V. A., Bambrick, L. L., Yarowsky, P., Krueger, B. K., & Blaustein, M. P. (1996) · Glia · doi:10.1002/(sici)1098-1136(199604)16:4 · Cited by 80
Obara, Y., Kobayashi, H., Ohta, T., Ohizumi, Y., & Nakahata, N. (2001) · Molecular Pharmacology · doi:10.1016/s0026-895x(24)12590-4 · Cited by 71
Penkowa, M., & Moos, T. (1995) · Glia · doi:10.1002/glia.440130308 · Cited by 71
Mandell, J. W., Gocan, N. C., & VandenBerg, S. R. (2001) · Glia · doi:10.1002/glia.1062 · Cited by 70
Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro
Zhang, D., Hu, X., Li, Q., Wilson, B. C., Lee, C., Flood, P. M., Langenbach, R. J., & Hong, J. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.04.015 · Cited by 69
Ghareghani, M., Zibara, K., Sadeghi, H., Dokoohaki, S., Sadeghi, H., Aryanpour, R., & Ghanbari, A. (2017) · Scientific Reports · doi:10.1038/s41598-017-04968-z · Cited by 68
Models of brain injury and alterations in synaptic plasticity
Albensi, B. C. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1151 · Cited by 68
DiProspero, N. A., Meiners, S. A., & Geller, H. M. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6700 · Cited by 68
Oligodendroglial Response to the Immune Cytokine Interferon Gamma
Popko, B., & Baerwald, K. D. (1999) · Neurochemical Research · doi:10.1023/a:1022586726510 · Cited by 68
Regional distribution of neurotrophin receptors in the developing auditory brainstem
Hafidi, A., Moore, T., & Sanes, D. H. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960408)367:3 · Cited by 51
Zhang, Z., Zhou, Y.-J., Gu, P., Zhao, W., Chen, H., Wu, R.-Y., Zhou, L., Cui, Q.-Z., Sun, S.-K., Zhang, L., et al. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.368300 · Cited by 68
Tackling the glial scar in spinal cord regeneration: new discoveries and future directions
Shafqat, A., Albalkhi, I., Magableh, H. M., Saleh, T., AlKattan, K. M., & Yaqinuddin, A. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1180825 · Cited by 71
Yamashita, K., Vogel, P., Fritze, K., Back, T., Hossmann, K., & Wießner, C. (1996) · Brain Research · doi:10.1016/0006-8993(96)00578-1 · Cited by 62
Signaling molecules and neuroglial activation in the injured central nervous system.
Raivich, G., Bluethmann, H., & Kreutzberg, G. (1996) · The Keio Journal of Medicine · doi:10.2302/kjm.45.239 · Cited by 67
Radford, R. A. W., Rcom-H'cheo-Gauthier, A. N., Wong, M. B., Eaton, E. D., Quilty, M., Blizzard, C. A., Norazit, A., Meedeniya, A. C. B., Vickers, J. C., Gai, W., et al. (2015) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2015.02.015 · Cited by 60
Teitelman, G., Guz, Y., Ivković, S., & Ehrlich, M. E. (1998) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(199803)34:4 · Cited by 60
The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms
Yu, Y., Chen, R., Mao, K., Deng, M., & Li, Z. (2023) · Aging and Disease · doi:10.14336/ad.2023.0718 · Cited by 62
Neurotoxicant-induced inflammatory response in three-dimensional brain cell cultures
Monnet‐Tschudi, F., Zurich, M., & Honegger, P. (2007) · Human & Experimental Toxicology · doi:10.1177/0960327107074589 · Cited by 59
Ding, Y. P., Zhang, T., Wu, G., McBride, D. W., Xu, N., Klebe, D. W., Zhang, Y., Li, Q., Tang, J., & Zhang, J. H. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.113003 · Cited by 61
Neurotoxic consequences of central long-term administration of interleukin-2 in rats
Hanisch, U., Neuhaus, J., Rowe, W. B., van Rossum, D., Möller, T., Kettenmann, H., & Quirion, R. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00040-7 · Cited by 59
Maturation‐dependent neurotoxicity of lead acetate in vitro: Implication of glial reactions
Zurich, M., Eskes, C., Honegger, P., Bérode, M., & Monnet‐Tschudi, F. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10367 · Cited by 60
Penkowa, M., Giralt, M., Moos, T., Thomsen, P. S., Hernández, J., & Hidalgo, J. (1999) · Experimental Neurology · doi:10.1006/exnr.1998.7009 · Cited by 59
Mice lacking NT-3, and its receptor TrkC, exhibit profound deficiencies in CNS glial cells
Kahn, M. A., Kumar, S., Liebl, D. J., Chang, R., Parada, L. F., & de Vellis, J. (1999) · Glia · doi:10.1002/(sici)1098-1136(199904)26:2 · Cited by 99
Martínez-Contreras, A., Huerta, M., López‐Pérez, S. J., Garcı́a‐Estrada, J., Luquı́n, S., & Zárate, C. B. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.10093 · Cited by 58
Beaulieu, J., Križ, J., & Julien, J. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02830-5 · Cited by 57
Gliomatosis peritonei: a report of two cases and review of the literature
Müller, A. M., Söndgen, D., Strunz, R., & Müller, K.-M. (2002) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(01)00486-9 · Cited by 57
Plata‐Saláman, C. R., Ilyin, S. E., Gayle, D. A., Romanovitch, A. E., & Carbone, K. M. (1999) · Brain Research Bulletin · doi:10.1016/s0361-9230(99)00081-7 · Cited by 56
Exercise-Induced Modulation of Neuroinflammation in Models of Alzheimer’s Disease
Kelly, Á. M. (2018) · Brain Plasticity · doi:10.3233/bpl-180074 · Cited by 55
Köller, H., Thiem, K., & Siebler, M. (1996) · Brain · doi:10.1093/brain/119.6.2021 · Cited by 55
Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis
Livne‐Bar, I., Lam, S., Chan, D. W.-H., Guo, X., Askar, I., Nahirny, A., Flanagan, J. G., & Sivak, J. M. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.277 · Cited by 56
Werner, A., Kloss, C. U. A., Walter, J., Kreutzberg, G. W., & Raivich, G. (1998) · Journal of Neurocytology · doi:10.1023/a:1006928830251 · Cited by 51
Gomide, V. C., & Chadi, G. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01557-7 · Cited by 51
houcke, J. V., Mariën, V., Zandecki, C., Vanhunsel, S., Moons, L., Ayana, R., Seuntjens, E., & Arckens, L. (2021) · Aging Cell · doi:10.1111/acel.13464 · Cited by 51
Kulas, J. A., Hettwer, J. V., Sohrabi, M., Melvin, J. E., Manocha, G. D., Puig, K. L., Gorr, M. W., Tanwar, V., McDonald, M. P., Wold, L. E., et al. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.05.047 · Cited by 50
IL‐1β and IL‐10 have dual effects on enteric glial cell proliferation
Rühl, A., Franzke, S., & Stremmel, W. (2001) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2001.00245.x · Cited by 49
Anti-inflammatory drugs: a hope for Alzheimer’s disease?
Hüll, M., Lieb, K., & Fiebich, B. L. (2000) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.9.4.671 · Cited by 49
Heightened intrathecal release of proinflammatory cytokines in Creutzfeldt–Jakob disease
Sharief, M. K., Green, A. J. E., Dick, J. P. R., Gawler, J., & Thompson, E. J. (1999) · Neurology · doi:10.1212/wnl.52.6.1289 · Cited by 48
Otani, N., Nawashiro, H., Fukui, S., Nomura, N., & Shima, K. (2002) · Journal of Neurotrauma · doi:10.1089/089771502762300247 · Cited by 48
Liu, W., Lee, Y., Tsai, S., Hsu, C. Y., Sun, Y., Yang, L., Tsai, S., & Yang, W. V. (2008) · Glia · doi:10.1002/glia.20706 · Cited by 48
Johansson, S., & Strömberg, I. (2002) · The Journal of Comparative Neurology · doi:10.1002/cne.10119 · Cited by 48
Neuron–glia signaling: Implications for astrocyte differentiation and synapse formation
Stipursky, J., Romão, L. F., Tortelli, V., Moura‐Neto, V., & Gomes, F. C. A. (2011) · Life Sciences · doi:10.1016/j.lfs.2011.04.005 · Cited by 52
Perspectives on Brain Tumor Formation Involving Macrophages, Glia, and Neural Stem
Seyfried, T. N. (2001) · Perspectives in biology and medicine · doi:10.1353/pbm.2001.0035 · Cited by 47
Neurogenesis, Exercise, and Cognitive Late Effects of Pediatric Radiotherapy
Rodgers, S. P., Treviño, M., Zawaski, J. A., Gaber, M. W., & Leasure, J. L. (2013) · Neural Plasticity · doi:10.1155/2013/698528 · Cited by 47
Hayashi, Y., Nomura, M., Yamagishi, S., Harada, S.-I., Yamashita, J., & Yamamoto, H. (1997) · Glia · doi:10.1002/(sici)1098-1136(199701)19:1 · Cited by 292
Pasterkamp, R. J., de Winter, F., Giger, R. J., & Verhaagen, J. (1998) · Progress in brain research · doi:10.1016/s0079-6123(08)64014-5 · Cited by 46
Stohlman, S. A., Hinton, D. R., Cua, D., Dimacali, E., Sensintaffar, J., Hofman, F. M., Tahara, S. M., & Yao, Q. (1995) · Journal of Virology · doi:10.1128/jvi.69.9.5898-5903.1995 · Cited by 46
Gozal, E., Jagadapillai, R., Cai, J., & Barnes, G. N. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15460 · Cited by 45
Regulatory role of resveratrol on Th17 in autoimmune disease
Petro, T. M. (2010) · International Immunopharmacology · doi:10.1016/j.intimp.2010.07.011 · Cited by 45
REGENERATION IN THE VERTEBRATE CENTRAL NERVOUS SYSTEM: PHYLOGENY, ONTOGENY, AND MECHANISMS
Larner, A. J., Johnson, A. R., & Keynes, R. J. (1995) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1995.tb01653.x · Cited by 44
Hyaluronate‐based extracellular matrix: Keeping glia in their place
Sherman, L. S., Struve, J. N., Rangwala, R. A., Wallingford, N. M., Tuohy, T. M. F., & Kuntz, C. (2002) · Glia · doi:10.1002/glia.10053 · Cited by 44
Vallières, L. (1999) · Endocrinology · doi:10.1210/en.140.9.3890 · Cited by 44
Ricci‐Vitiani, L., Casalbore, P., Petrucci, G., Lauretti, L., Montano, N., Larocca, L. M., Falchetti, M. L., Lombardi, D. G., Gerevini, V. D. G., Cenciarelli, C., et al. (2006) · Neurological Research · doi:10.1179/016164106x115134 · Cited by 43
Brown, D. R. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0720943.x · Cited by 42
IL6 Protects MN9D Cells and Midbrain Dopaminergic Neurons from MPP+-Induced Neurodegeneration
Spittau, B., Zhou, X., Ming, M., & KRIEGLSTEIN, K. G. (2012) · NeuroMolecular Medicine · doi:10.1007/s12017-012-8189-7 · Cited by 41
Acarín, L., González, B., Castellano, B., & Castro, A. J. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6593 · Cited by 41
Methylprednisolone treatment delays remote cell death after focal brain lesion
Viscomi, M. T., Florenzano, F., Latini, L., Amantea, D., Bernardi, G., & Molinari, M. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.04.024 · Cited by 40
Expression of Full-Length trkB Receptors by Reactive Astrocytes after Chronic CNS Injury
McKeon, R. J., Silver, J., & Large, T. H. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6698 · Cited by 40
Fujita, H., Tanaka, J., Toku, K., Tateishi, N., Suzuki, Y., Matsuda, S., Sakanaka, M., & Maeda, N. (1996) · Glia · doi:10.1002/(sici)1098-1136(199612)18:4 · Cited by 128
Expression of interleukin 6 in the rat striatum following stereotaxic injection of quinolinic acid
Schiefer, J., Töpper, R., Schmidt, W., Block, F., Heinrich, P. C., Noth, J., & Schwarz, M. (1998) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(98)00133-7 · Cited by 38
Astrocytes and developmental white matter disorders
Sen, E., & Levison, S. W. (2006) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20106 · Cited by 37
Roymans, D., Vissenberg, K., Jonghe, C. D., Grobben, B., Claes, P., Verbelen, J., Broeckhoven, C. V., & Slegers, H. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00077.x · Cited by 37
Röhl, C., Armbrust, E., Kolbe, K., Lucius, R., Maser, E., Venz, S., & Gülden, M. (2008) · Glia · doi:10.1002/glia.20683 · Cited by 36
The Glial Cells Respond to Spinal Cord Injury
Wang, R., Zhou, R., Chen, Z., Gao, S., & Zhou, F. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.844497 · Cited by 35
Miller, D. B., O'Callaghan, J. P., & Ali, S. F. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05196.x · Cited by 36
Petitto, J. M., Huang, Z., Raizada, M. K., Rinker, C. M., & McCarthy, D. B. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00276-3 · Cited by 36
Avraham, Y., Grigoriadis, N. K., Magen, I., Poutahidis, T., Vorobiav, L., Zolotarev, O., Ilan, Y., Mechoulam, R., & Berry, E. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00368.x · Cited by 35
Kundu, M., Sharma, S., Luca, A. D., Giordano, A., Rappaport, J., Khalili, K., & Amini, S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.14.8130 · Cited by 35
Smith, J. S., Fulop, Z. L., Levinsohn, S. A., Darrell, R. S., & Stein, D. G. (2000) · Neural Plasticity · doi:10.1155/np.2000.73 · Cited by 33
Kong, G., Kristensson, K., & Bentivoglio, M. (2002) · Glia · doi:10.1002/glia.10030 · Cited by 34
Balasubramaniam, J., Xue, M., Buist, R. J., Ivanco, T. L., Natuik, S. A., & Bigio, M. R. D. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.09.010 · Cited by 33
Fülöp, B., Hunyady, Á., Bencze, N., Kormos, V., Szentes, N., Dénes, Á., Lénárt, N., Borbély, É., & Helyes, Z. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065479 · Cited by 35
Wang, Q., Ding, H., Chen, S., Liu, X., Deng, Y., Jiang, W., Li, Y., Huang, L., Han, Y., Wen, M., et al. (2020) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13427 · Cited by 32
Haemophilus influenzaePorin Contributes to Signaling of the Inflammatory Cascade in Rat Brain
Galdiero, M., D’Amico, M., Gorga, F., Filippo, C. D., D’Isanto, M., Vitiello, M., Longanella, A., & Tortora, A. (2001) · Infection and Immunity · doi:10.1128/iai.69.1.221-227.2001 · Cited by 32
Polikov, V. S., Su, E. C., Ball, M. A., Hong, J., & Reichert, W. M. (2009) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2009.05.002 · Cited by 32
Molecular Characterization of Glioblastoma Cell Differentiation
Engelhard, H. H., Duncan, H. A., & Canto, M. D. (1997) · Neurosurgery · doi:10.1097/00006123-199710000-00023 · Cited by 32
Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults
Sterpka, A., Yang, J., Strobel, M., Zhou, Y., Pauplis, C., & Chen, X. (2020) · Molecular Brain · doi:10.1186/s13041-020-00571-y · Cited by 30
Metadata
- Authors
- Balasingam, V, Tejada-Berges, T., Wright, E., Bouckova, R., & Yong, V.
- Affiliations
- McGill University (CA)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 1994-02-01
- Volume
- 14
- Issue
- 2
- Pages
- 846-856
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6576825
- OpenAlex
- W2158406932
- Cited by
- 342
- References
- 63
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 3 · 2023: 6 · 2022: 4 · 2021: 6 · 2020: 6 · 2019: 7 · 2018: 7 · 2017: 8 · 2016: 5 · 2015: 6 · 2014: 6 · 2013: 14 · 2012: 7
- FWCI
- 13.60
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Government of Canada
- Medical Research Council Canada
- Medical Research Council
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Clinical Neurology › Spinal Cord Injury Research
- Keywords
- reactive astrogliosis, neonatal brain, cytokines, astrocytes, stab wounds, glial fibrillary acidic protein, interferon-gamma, neuroinflammation, neonatal mice
- MeSH terms
- Animals, Animals, Newborn, Astrocytes, Brain, Brain Injuries, Cell Division, DNA, Female, Glial Fibrillary Acidic Protein, Humans, Inflammation, Interferon-gamma, Interleukin-1, Interleukin-2, Male, Mice, Inbred Strains, Microinjections, Recombinant Proteins, Thymidine, Time Factors, Tumor Necrosis Factor-alpha, Wounds, Stab, Biomarkers, Interleukin-6, Macrophage Colony-Stimulating Factor, Cytokines, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review