Cited by 125Neuroscience and Neuropharmacology ResearchNeuroendocrine regulation and behaviorHypothalamic control of reproductive hormones

The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.

Synaptic plasticity in the rat supraoptic nucleus during lactation involves GABA innervation and oxytocin neurons: a quantitative immunocytochemical analysis

Open access

Gies, U, Theodosis, DT·1994·The Journal of Neuroscience

DOI 10.1523/jneurosci.14-05-02861.1994PMC PMC6577499

Open this paper in CoChat — free account Open PDF

Abstract

The hypothalamic supraoptic nucleus (SON) is known to undergo synaptic remodeling in response to physiological stimuli, such as lactation. We here investigated the involvement of the GABAergic innervation in such plasticity by carrying out comparative ultrastructural analyses after postembedding immunogold labeling for GABA on sections of the SON from virgin and lactating rats. Using random single-section analysis to estimate the numerical density of synapses (from areal measurements of the anterior, mid, and posterior portions of the nucleus), we found that the overall density in either group was about 35 x 10(6) synapses/mm3, of which over one-third were GABA immunoreactive. The GABAergic terminals formed mainly symmetrical synaptic contact on neurosecretory somata and dendrites; the density of axodendritic contacts was twice that of axosomatic contacts. Despite hypertrophy of the neurosecretory neurons in lactating rats, the overall synaptic density did not diminish and was similar to that evaluated in virgin rats. When we estimated synaptic densities in the neuropil (by subtracting the proportion of sampled areas occupied by soma profiles), we found a statistically significant increase in the density of GABAergic synapses, in particular in the mid and posterior portions of the SON in lactating animals. On the other hand, the density of GABA- immunonegative synapses did not differ in the two groups. Terminals contacting more than one postsynaptic element in the same plane of section (“shared” synapses) were visible in the nuclei of virgin and lactating rats and about half in each group were GABAergic. They were comparatively rare but their incidence doubled in lactating animals.(ABSTRACT TRUNCATED AT 250 WORDS)

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1523/jneurosci.14-05-02861.1994

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The rat brain in stereotaxic coordinates
Palkovits, M. (1983) · Neuropeptides · doi:10.1016/0143-4179(83)90049-5 · Cited by 28,959
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat
Sawchenko, P. E., & Swanson, L. W. (1982) · Brain Research Reviews · doi:10.1016/0165-0173(82)90010-8 · Cited by 1,141
Electrophysiology of hypothalamic magnocellular neurones secreting oxytocin and vasopressin
Poulain, D. A., & Wakerley, J. B. (1982) · Neuroscience · doi:10.1016/0306-4522(82)90044-6 · Cited by 816
GABA: A dominant neurotransmitter in the hypothalamus
Decavel, C., & van den Pol, A. N. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.903020423 · Cited by 575
Glutamate, the Dominant Excitatory Transmitter in Neuroendocrine Regulation
van den Pol, A. N., Wuarin, J., & Dudek, F. E. (1990) · Science · doi:10.1126/science.1978759 · Cited by 544
Immunohistochemical analysis of magnocellular elements in rat hypothalamus: Distribution and numbers of cells containing neurophysin, oxytocin, and vasopressin
Rhodes, C. H., Morriell, J. I., & Pfaff, D. W. (1981) · The Journal of Comparative Neurology · doi:10.1002/cne.901980106 · Cited by 536
Emerging concepts of structure-function dynamics in adult brain: The hypothalamo-neurohypophysial system
Hatton, G. I. (1990) · Progress in Neurobiology · doi:10.1016/0301-0082(90)90017-b · Cited by 439
The distribution and cells of origin of serotonergic inputs to the paraventricular and supraoptic nuclei of the rat
Sawchenko, P. E., Swanson, L. W., Steinbusch, H. W. M., & Verhofstad, A. A. J. (1983) · Brain Research · doi:10.1016/0006-8993(83)90945-9 · Cited by 380
Local origins of some GABAergic projections to the paraventricular and supraoptic nuclei of the hypothalamus in the rat
Roland, B. L., & Sawchenko, P. E. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903320109 · Cited by 334

Show all 49 references

Sorted by citations

Activity-dependent structural and functional plasticity of astrocyte-neuron interactions
Theodosis, D. T., Poulain, D. A., & Oliet, S. H. R. (2008) · Physiological Reviews · doi:10.1152/physrev.00036.2007 · Cited by 531
Self-citation
The hypothalamic-neurohypophysial system regulates the hypothalamic–pituitary–adrenal axis under stress: an old concept revisited
Engelmann, M., Landgraf, R., & Wotjak, C. T. (2004) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2004.09.001 · Cited by 450
Physiology of BDNF: focus on hypothalamic function
Tapia‐Arancibia, L. (2004) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2004.04.001 · Cited by 378
Gene Regulation in the Magnocellular Hypothalamo-Neurohypophysial System
Burbach, J. P. H., Luckman, S. M., Murphy, D., & Gainer, H. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1197 · Cited by 344
Dendritic Release of Vasopressin and Oxytocin
Ludwig (1998) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1998.00279.x · Cited by 342
Function-related plasticity in hypothalamus.
Hatton, G. I. (1997) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.20.1.375 · Cited by 331
Activity-dependent neuronal-glial and synaptic plasticity in the adult mammalian hypothalamus
Theodosis, D. T., & Poulain, D. A. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90002-w · Cited by 273
Self-citation
Morphological and electrophysiological classification of hypothalamic supraoptic neurons
Armstrong, W. E. (1995) · Progress in Neurobiology · doi:10.1016/0301-0082(95)80005-s · Cited by 246
Plasticity in Fast Synaptic Inhibition of Adult Oxytocin Neurons Caused by Switch in GABAA Receptor Subunit Expression
Brussaard, A. B., Kits, K. S., Baker, R. E., Willems, W. P. A., Leyting-Vermeulen, J. W., Voorn, P., Smit, A. B., Bicknell, R. J., & Herbison, A. E. (1997) · Neuron · doi:10.1016/s0896-6273(00)80401-8 · Cited by 228
Oxytocin-Secreting Neurons: A Physiological Model of Morphological Neuronal and Glial Plasticity in the Adult Hypothalamus
Theodosis, D. T. (2002) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2001.0226 · Cited by 231
Self-citation
Osmotic regulation of neuronal activity: a new role for taurine and glial cells in a hypothalamic neuroendocrine structure
Hussy, N., Deleuze, C., Desarménien, M. G., & Moos, F. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00071-4 · Cited by 207
Chapter 1 Brain preparations for maternity — adaptive changes in behavioral and neuroendocrine systems during pregnancy and lactation. An overview
Russell, J. A., Douglas, A. J., & Ingram, C. D. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)33002-9 · Cited by 187
GABAergic innervation of corticotropin-releasing hormone (CRH)-secreting parvocellular neurons and its plasticity as demonstrated by quantitative immunoelectron microscopy
Miklós, I. H., & Kovács, K. J. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00147-1 · Cited by 182
Plastic Changes in Glycine and GABA Release and Uptake in Adult Brain Stem Auditory Nuclei after Unilateral Middle Ear Ossicle Removal and Cochlear Ablation
Suneja, S. K., Potashner, S. J., & Benson, C. G. (1998) · Experimental Neurology · doi:10.1006/exnr.1998.6812 · Cited by 173
Costorage and coexistence of neuropeptides in the mammalian CNS
Merighi, A. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(01)00031-4 · Cited by 160
Chronic stress‐induced neurotransmitter plasticity in the PVN
Flak, J. N., Ostrander, M. M., Tasker, J. G., & Herman, J. P. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22142 · Cited by 140
NO inhibits supraoptic oxytocin and vasopressin neurons via activation of GABAergic synaptic inputs
Stern, J. E., & Ludwig, M. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.280.6.r1815 · Cited by 139
Changes in properties and neurosteroid regulation of GABAergic synapses in the supraoptic nucleus during the mammalian female reproductive cycle
Brussaard, A. B., Dévay, P., Leyting-Vermeulen, J. W., & Kits, K. S. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.0513v.x · Cited by 131
Reorganization of the Dendritic Trees of Oxytocin and Vasopressin Neurons of the Rat Supraoptic Nucleus during Lactation
Stern, J. E., & Armstrong, W. E. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-03-00841.1998 · Cited by 130
Immobilization stress rapidly modulates BDNF mRNA expression in the hypothalamus of adult male rats
Rage, F., Givalois, L., Marmigère, F., Tapia‐Arancibia, L., & Arancibia, S. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00072-6 · Cited by 126
The maternal brain: an organ with peripartal plasticity
Hillerer, K. M., Jacobs, V. R., Fischer, T., & Aigner, L. (2014) · Neural Plasticity · doi:10.1155/2014/574159 · Cited by 120
Evidence for a Hypothalamic Oxytocin-Sensitive Pattern-Generating Network Governing Oxytocin NeuronsIn Vitro
Jourdain, P., Israël, J.-M., Dupouy, B., Oliet, S. H. R., Michèle Allard, A., Vitiello, S., Theodosis, D. T., & Poulain, D. A. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-17-06641.1998 · Cited by 118
Self-citation
Neuroendocrine Regulation of Lactation and Milk Production
Crowley, W. R. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140029 · Cited by 135
Neural circuitry for maternal oxytocin release induced by infant cries
Valtcheva, S., Issa, H. A., Bair-Marshall, C. J., Martin, K. A., Jung, K., Zhang, Y., Kwon, H.-B., & Froemke, R. C. (2023) · Nature · doi:10.1038/s41586-023-06540-4 · Cited by 115
Maternal behaviour in lactating rats stimulates c-fos in glutamate decarboxylase-synthesizing neurons of the medial preoptic area, ventral bed nucleus of the stria terminalis, and ventrocaudal periaqueductal gray
Lonstein, J. S., & Vries, G. J. D. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00287-6 · Cited by 111
Adenosine‐induced presynaptic inhibition of IPSCs and EPSCs in rat hypothalamic supraoptic nucleus neurones
Oliet, S. H. R., & Poulain, D. A. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.00815.x · Cited by 109
Synaptic remodeling induced by gonadal hormones: Neuronal plasticity as a mediator of neuroendocrine and behavioral responses to steroids
Párducz, Á., Hajszán, T., MacLusky, N. J., Hoyk, Z., Csakvari, E., Kurunczi, A., Prange‐Kiel, J., & Leranth, C. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.07.008 · Cited by 109
Retrograde Regulation of GABA Transmission by the Tonic Release of Oxytocin and Endocannabinoids Governs Postsynaptic Firing
Oliet, S. H. R., Baimoukhametova, D. V., Piet, R., & Bains, J. S. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2676-06.2007 · Cited by 107
Neuronal, glial and synaptic remodeling in the adult hypothalamus: functional consequences and role of cell surface and extracellular matrix adhesion molecules
Theodosis, D. T., Piet, R., Poulain, D. A., & Oliet, S. H. R. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.11.003 · Cited by 105
Self-citation
Changes in the Electrical Properties of Supraoptic Nucleus Oxytocin and Vasopressin Neurons during Lactation
Stern, J. E., & Armstrong, W. E. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-16-04861.1996 · Cited by 104
Activity‐related, dynamic neuron‐glial interactions in the hypothalamo‐neurohypophysial system
Miyata, S., & Hatton, G. I. (2002) · Microscopy Research and Technique · doi:10.1002/jemt.10012 · Cited by 98
Glial modulation of synaptic transmission: Insights from the supraoptic nucleus of the hypothalamus
Oliet, S. H. R., Piet, R., Poulain, D. A., & Theodosis, D. T. (2004) · Glia · doi:10.1002/glia.20032 · Cited by 98
Self-citation
Peptidomic Identification and Biological Validation of Neuroendocrine Regulatory Peptide-1 and -2
Yamaguchi, H., Sasaki, K., Satomi, Y., Shimbara, T., Kageyama, H., Mondal, M. S., Toshinai, K., Date, Y., González, L. J., Shioda, S., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m701665200 · Cited by 94
Dehydration-Induced Synaptic Plasticity in Magnocellular Neurons of the Hypothalamic Supraoptic Nucleus
Di, S., & Tasker, J. G. (2004) · Endocrinology · doi:10.1210/en.2004-0702 · Cited by 87
The Glutamatergic Innervation of Oxytocin‐ and Vasopressin‐secreting Neurons in the Rat Supraoptic Nucleus and its Contribution to Lactation‐induced Synaptic Plasticity
Majdoubi, M. E., Poulain, D. A., & Theodosis, D. T. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01600.x · Cited by 86
Self-citation
Lactation-induced plasticity in the supraoptic nucleus augments axodendritic and axosomatic GABAergic and glutamatergic synapses: an ultrastructural analysis using the disector method
Majdoubi, M. E., Poulain, D. A., & Theodosis, D. T. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00193-0 · Cited by 86
Self-citation
Plasticity in GABAAReceptor Subunit mRNA Expression by Hypothalamic Magnocellular Neurons in the Adult Rat
Fénelon, V. S., & Herbison, A. E. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-16-04872.1996 · Cited by 83
GABA‐induced facilitation of the periodic bursting activity of oxytocin neurones in suckled rats.
Moos, F. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp020949 · Cited by 79
Remodeling of astrocytes, a prerequisite for synapse turnover in the adult brain? Insights from the oxytocin system of the hypothalamus
Theodosis, D. T., Trailin, A., & Poulain, D. A. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00755.2005 · Cited by 77
Self-citation
Endogenous opioid regulation of stress-induced oxytocin release within the hypothalamic paraventricular nucleus is reversed in late pregnancy: a microdialysis study
Wigger, A., & Neumann, I. D. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00068-4 · Cited by 74
Adolescent exposure to anabolic/androgenic steroids and the neurobiology of offensive aggression: A hypothalamic neural model based on findings in pubertal Syrian hamsters
Melloni, R. H., & Ricci, L. A. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.11.002 · Cited by 72
Factors Governing Activity-Dependent Structural Plasticity of the Hypothalamoneurohypophysial System
Theodosis, D. T., Majdoubi, M. E., Pierre, K., & Poulain, D. A. (1998) · Cellular and Molecular Neurobiology · doi:10.1023/a:1022577105819 · Cited by 69
Self-citation
Enhanced neurotransmitter release at glutamatergic synapses on oxytocin neurones during lactation in the rat
Stern, J. E., Hestrin, S., & Armstrong, W. E. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00109.x · Cited by 68
Somato‐dendritic vasopressin and oxytocin secretion in endocrine and autonomic regulation
Brown, C. H., Ludwig, M., Tasker, J. G., & Stern, J. E. (2020) · Journal of Neuroendocrinology · doi:10.1111/jne.12856 · Cited by 72
Changes in the Active Membrane Properties of Rat Supraoptic Neurones During Pregnancy and Lactation
Teruyama, R., & Armstrong, W. E. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00844.x · Cited by 66
The role of astrocytes in the hypothalamic response and adaptation to metabolic signals
Chowen, J. A., Argente-Arizón, P., Freire‐Regatillo, A., Frago, L. M., Horváth, T. L., & Argente, J. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.03.001 · Cited by 68
Topographic organization of medial pulvinar connections with the prefrontal cortex in the rhesus monkey
Romanski, L. M., Giguere, M., Bates, J. F., & Goldman-Rakic, P. S. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970317)379:3 · Cited by 323
Self-citation
Metabolic mapping of the brain in pregnant, parturient and lactating rats using Fos immunohistochemistry
Lin, S., Miyata, S., Matsunaga, W., Kawarabayashi, T., Nakashima, T., & Kiyohara, T. (1998) · Brain Research · doi:10.1016/s0006-8993(97)01484-4 · Cited by 62
Central inhibitory effects of muscimol and bicuculline on the milk ejection reflex in the anaesthetized rat.
Voisin, D. L., Herbison, A. E., & Poulain, D. A. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp020579 · Cited by 63
Oxytocin and estrogen promote rapid formation of functional GABA synapses in the adult supraoptic nucleus
Theodosis, D. T., Koksma, J.-J., Trailin, A., Langle, S. L., Piet, R., Lodder, J. C., Timmerman, J. A., Mansvelder, H. D., Poulain, D. A., Oliet, S. H. R., et al. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.01.006 · Cited by 64
Self-citation
Neurophysiological and cognitive changes in pregnancy
Grattan, D. R., & Ladyman, S. R. (2020) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64239-4.00002-3 · Cited by 66
Enhancement of calcium‐dependent afterpotentials in oxytocin neurons of the rat supraoptic nucleus during lactation
Teruyama, R., & Armstrong, W. E. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.085985 · Cited by 59
The Role of Anabolic Androgenic Steroids in Disruption of the Physiological Function in Discrete Areas of the Central Nervous System
Bertozzi, G., Sessa, F., Albano, G. D., Sani, G., Maglietta, F., Roshan, M. H. K., Volti, G. L., Bernardini, R., Avola, R., Pomara, C., et al. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0774-1 · Cited by 58
Oxytocin receptor binding in the hypothalamus during gestation in rats
Bealer, S. L., Lipschitz, D. L., Ramoz, G., & Crowley, W. R. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00766.2005 · Cited by 54
Chapter 3 Maternity leads to morphological synaptic plasticity in the oxytocin system
Theodosis, D. T., & Poulain, D. A. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)33004-2 · Cited by 56
Self-citation
Contribution of Astrocytes to Activity-Dependent Structural Plasticity in the Adult Brain
Theodosis, D. T., & Poulain, D. A. (1999) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4685-6_14 · Cited by 55
Self-citation
Activation of Presynaptic GABAB Receptors Inhibits Evoked IPSCs in Rat Magnocellular Neurons In Vitro
Mouginot, D., Kombian, S. B., & Pittman, Q. J. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.3.1508 · Cited by 52
Neuropeptides as neuroprotective agents: oxytocin a forefront developmental player in the mammalian brain
Vargas-Martínez, F., Uvnäs-Moberg, K., Petersson, M., Olausson, H. A., & Jiménez-Estrada, I. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2014.10.001 · Cited by 51
Visualization of local afferent inputs to magnocellular oxytocin neurons in vitro
Jourdain, P., Dupouy, B., Bonhomme, R., Poulain, D. A., Israël, J.-M., & Theodosis, D. T. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00620.x · Cited by 50
Self-citation
Inhibition of spontaneous inhibitory postsynaptic currents (IPSC) by noradrenaline in rat supraoptic neurons through presynaptic α2-adrenoceptors
Wang, Y., Shibuya, I., Kabashima, N., Setiadji, V. S., Isse, T., Ueta, Y., & Yamashita, H. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00732-x · Cited by 48
Dopamine D4 Receptor-Mediated Presynaptic Inhibition of GABAergic Transmission in the Rat Supraoptic Nucleus
Azdad, K., Piet, R., Poulain, D. A., & Oliet, S. H. R. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00226.2003 · Cited by 47
Alterations in the anterior hypothalamic dopamine system in aggressive adolescent AAS-treated hamsters
Ricci, L. A., Schwartzer, J. J., & Melloni, R. H. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.10.011 · Cited by 43
Neuronal–glial remodeling: a structural basis for neuronal–glial interactions in the adult hypothalamus
Langle, S. L., Poulain, D. A., & Theodosis, D. T. (2002) · Journal of Physiology-Paris · doi:10.1016/s0928-4257(02)00003-7 · Cited by 45
Self-citation
Effects of Serotonin Inhibition on Neuronal and Astrocyte Plasticity in the Phrenic Nucleus 4 h Following C2 Spinal Cord Hemisection
Hadley, S. D., Walker, P. D., & Goshgarian, H. G. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7238 · Cited by 42
Adhesion molecules and structural plasticity of the adult hypothalamo-neurohypophysial system
Theodosis, D. T., Bonfanti, L., Olive, S., Rougon, G. N., & Poulain, D. A. (1994) · Psychoneuroendocrinology · doi:10.1016/0306-4530(94)90032-9 · Cited by 42
Self-citation
Chapter 9 Functional synaptic plasticity in hypothalamic magnocellular neurons
Tasker, J. G., Di, S., & Boudaba, C. (2002) · Progress in brain research · doi:10.1016/s0079-6123(02)39011-3 · Cited by 41
Chapter 8 Glial cells in the hypothalamo-neurohypophysial system: key elements of the regulation of neuronal electrical and secretory activity
Hussy, N. (2002) · Progress in brain research · doi:10.1016/s0079-6123(02)39010-1 · Cited by 40
Immunolocalization of glutathione reductase in the murine brain
Knollema, S., Hom, H. W., Schirmer, H., Korf, J., & Horst, G. J. T. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960916)373:2 · Cited by 27
Glia-Dependent Switch of Kainate Receptor Presynaptic Action
Bonfardin, V. D. J., Fossat, P., Theodosis, D. T., & Oliet, S. H. R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3389-09.2010 · Cited by 36
Self-citation
Modulation of GABAergic transmission by endogenous glutamate in the rat supraoptic nucleus
Piet, R., Bonhomme, R., Theodosis, D. T., Poulain, D. A., & Oliet, S. H. R. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02611.x · Cited by 40
Self-citation
Integrative neurohumoural regulation of oxytocin neurone activity in pregnancy and lactation
Augustine, R. A., Seymour, A. J., Campbell, R. E., Grattan, D. R., & Brown, C. H. (2018) · Journal of Neuroendocrinology · doi:10.1111/jne.12569 · Cited by 38
Characterisation of GABAA receptor gamma subunit expression by magnocellular neurones in rat hypothalamus
Fénelon, V. S., & Herbison, A. E. (1995) · Molecular Brain Research · doi:10.1016/0169-328x(95)00130-k · Cited by 37
NMDA-Mediated Activation of the Medial Amygdala Initiates a Downstream Neuroendocrine Memory Responsible for Pseudopregnancy in the Female Rat
Polston, E. K., Heitz, M., Barnes, W., Cardamone, K., & Erskine, M. S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-11-04104.2001 · Cited by 36
Activity-dependent morphological synaptic plasticity in an adult neurosecretory system: magnocellular oxytocin neurons of the hypothalamus
Majdoubi, M. E., Poulain, D. A., & Theodosis, D. T. (2000) · Biochemistry and Cell Biology · doi:10.1139/o00-023 · Cited by 35
Self-citation
Neuroendocrine Regulation of Lactation and Milk Production
Crowley, W. R. (2015) · Comprehensive physiology · doi:10.1002/j.2040-4603.2015.tb00607.x · Cited by 34
Electrophysiological Distinctions Between Oxytocin and Vasopressin Neurons in the Supraoptic Nucleus
Armstrong, W. E., & Stern, J. E. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4871-3_7 · Cited by 34
Interactions between the dopaminergic and GABAergic neural systems in the lateral anterior hypothalamus of aggressive AAS-treated hamsters
Schwartzer, J. J., Ricci, L. A., & Melloni, R. H. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.04.007 · Cited by 33
Fos synthesis in identified magnocellular neurons varies with phenotype, stimulus, location in the hypothalamus and reproductive state
Fénelon, V. S., Theodosis, D. T., & Poulain, D. A. (1994) · Brain Research · doi:10.1016/0006-8993(94)90809-5 · Cited by 33
Self-citation
Extracellular GABA concentrations in rat supraoptic nucleus during lactation and following haemodynamic changes: An in vivo microdialysis study
Voisin, D. L., Chapman, C., Poulain, D. A., & Herbison, A. E. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90549-5 · Cited by 33
Polysialic acid is required for active phases of morphological plasticity of neurosecretory axons and their glia
Monlezun, S., Ouali‐Hassenaoui, S., Poulain, D. A., & Theodosis, D. T. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.04.003 · Cited by 31
Self-citation
Structural and Functional Plasticity in the Maternal Brain Circuitry
Pereira, M. (2016) · New Directions for Child and Adolescent Development · doi:10.1002/cad.20163 · Cited by 31
Taurine selectively modulates the secretory activity of vasopressin neurons in conscious rats
Engelmann, M., Ludwig, M., Singewald, N., Ebner, K., Sabatier, N., Lübec, G., Landgraf, R., & Wotjak, C. T. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01729.x · Cited by 30
Synchronized bursts of miniature inhibitory postsynaptic currents
Popescu, I., Morton, L. A., Franco, A. J., Di, S., Ueta, Y., & Tasker, J. G. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2009.181461 · Cited by 28
Dopamine activity in the lateral anterior hypothalamus modulates AAS-induced aggression through D2 but not D5 receptors.
Schwartzer, J. J., & Melloni, R. H. (2010) · Behavioral Neuroscience · doi:10.1037/a0020899 · Cited by 28
Chapter 2.1.3 Phenotypic and state-dependent expression of the electrical and morphological properties of oxytocin and vasopressin neurones
Armstrong, W. E., & Stern, J. E. (1999) · Progress in brain research · doi:10.1016/s0079-6123(08)61564-2 · Cited by 28
Lactation Alters γ-Aminobutyric Acid Neuronal Activity in the Hypothalamus and Cerebral Cortex in the Rat
Kornblatt, J. J., & Grattan, D. R. (2001) · Neuroendocrinology · doi:10.1159/000054634 · Cited by 27
Contribution of astrocytes to synaptic transmission in the rat supraoptic nucleus
Piet, R., Poulain, D. A., & Oliet, S. H. R. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.07.005 · Cited by 25
Deciphering the mechanisms of homeostatic plasticity in the hypothalamo-neurohypophyseal system—genomic and gene transfer strategies
Sharman, G., Ghorbel, M. T., Leroux, M., Beaucourt, S. M., Wong, L., & Murphy, D. (2004) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2003.11.005 · Cited by 24
GABA enhancement of maternal defense in mice: Possible neural correlates
Lee, G., & Gammie, S. C. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.12.023 · Cited by 23
Modulation of synaptic transmission by astrocytes in the rat supraoptic nucleus.
Piet, R., Poulain, D., & Oliet, S. (2002) · Journal of Physiology - Paris · doi:10.1016/s0928-4257(02)00010-4 · Cited by 25
Prolactin enhances hippocampal synaptic plasticity in female mice of reproductive age
Zamora‐Moratalla, A., & Martín, E. D. (2020) · Hippocampus · doi:10.1002/hipo.23288 · Cited by 21
Prostaglandin E2 Inhibits Spontaneous Inhibitory Postsynaptic Currents in Rat Supraoptic Neurones via Presynaptic EP Receptors
Ibrahim, N., Shibuya, I., Kabashima, Sutarmo, Ueta, & Yamashita (1999) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1999.00404.x · Cited by 22
Involvement of MCH-oxytocin neural relay within the hypothalamus in murine nursing behavior
Kato, Y., Katsumata, H., Inutsuka, A., Yamanaka, A., Onaka, T., Minami, S., & Orikasa, C. (2021) · Scientific Reports · doi:10.1038/s41598-021-82773-5 · Cited by 19
Neurochemical bases of plasticity in the magnocellular oxytocin system during gestation
Lipschitz, D. L., Crowley, W. R., Armstrong, W. E., & Bealer, S. L. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.08.003 · Cited by 18
Activity-Dependent Modulation of Neurotransmitter Innervation to Vasopressin Neurons of the Supraoptic Nucleus
Mueller, N. K., Di, S., Paden, C. M., & Herman, J. P. (2004) · Endocrinology · doi:10.1210/en.2004-0539 · Cited by 18
Spike patterning in oxytocin neurons: Capturing physiological behaviour with Hodgkin-Huxley and integrate-and-fire models
Leng, T., Leng, G., & MacGregor, D. J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180368 · Cited by 17
Glutamate Microstimulation of Local Inhibitory Circuits in the Supraoptic Nucleus From Rat Hypothalamus Slices
Wuarin, J. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.6.3180 · Cited by 16
Plasticity in the electrophysiological properties of oxytocin neurons
Armstrong, W. E., Stern, J. E., & Teruyama, R. (2002) · Microscopy Research and Technique · doi:10.1002/jemt.10019 · Cited by 15
Enzymatic removal of polysialic acid from neural cell adhesion molecule interrupts gonadotropin releasing hormone (GnRH) neuron–glial remodeling
Sushil Kumar, K., Parkash, J., Kataria, H., & Kaur, G. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.07.040 · Cited by 15
Tonic Regulation of GABAergic Synaptic Activity on Vasopressin Neurones by Cannabinoids
Wang, L., & Armstrong, W. E. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02239.x · Cited by 13

Authors: Gies, U., & Theodosis, D.
Affiliations: Justus-Liebig-Universität Gießen (DE)
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 1994-05-01
Volume: 14
Issue: 5
Pages: 2861-2869
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.14-05-02861.1994
PMC: PMC6577499
OpenAlex: W2119677102
Cited by: 125
References: 49
Citations by year: 2026: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 4 · 2015: 1 · 2014: 3 · 2013: 2
FWCI: 2.07
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-sa
creativecommons.org/licenses/by-nc-sa/4.0/ (vor, 184 d)
Locations: Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: European Science Foundation
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Keywords: synaptic plasticity, supraoptic nucleus, lactation, GABAergic innervation, oxytocin neurons, synaptic density, neurosecretory cells, axodendritic synapses, hypothalamus, ultrastructure
MeSH terms: Animals, Antibodies, Monoclonal, Axons, Dendrites, Female, gamma-Aminobutyric Acid, Lactation, Nerve Endings, Neuronal Plasticity, Neurons, Oxytocin, Pregnancy, Supraoptic Nucleus, Synapses, Microscopy, Immunoelectron, Rats, Wistar, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Synaptic plasticity in the rat supraoptic nucleus during lactation involves GABA innervation and oxytocin neurons: a quantitative immunocytochemical analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks