The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Maternal Influenza Infection Causes Marked Behavioral and Pharmacological Changes in the Offspring
Open accessAbstract
Maternal viral infection is known to increase the risk for schizophrenia and autism in the offspring. Using this observation in an animal model, we find that respiratory infection of pregnant mice (both BALB/c and C57BL/6 strains) with the human influenza virus yields offspring that display highly abnormal behavioral responses as adults. As in schizophrenia and autism, these offspring display deficits in prepulse inhibition (PPI) in the acoustic startle response. Compared with control mice, the infected mice also display striking responses to the acute administration of antipsychotic (clozapine and chlorpromazine) and psychomimetic (ketamine) drugs. Moreover, these mice are deficient in exploratory behavior in both open-field and novel-object tests, and they are deficient in social interaction. At least some of these behavioral changes likely are attributable to the maternal immune response itself. That is, maternal injection of the synthetic double-stranded RNA polyinosinic-polycytidylic acid causes a PPI deficit in the offspring in the absence of virus. Therefore, maternal viral infection has a profound effect on the behavior of adult offspring, probably via an effect of the maternal immune response on the fetus.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Altering the postnatal gut microbiota by early life treatment with the human gut bacterium Bacteroides fragilis sufficiently ameliorated deficits in the frequency and quality of adult ultrasonic vocalizations and reduced stereotypic burying behavior exhibited by the ASD-like mice.”
From Emerging Roles for the Gut Microbiome in Autism Spectrum Disorder (2017) · cites this paper as [31]
Experimental — accuracy not yet measuredIn the citing paper
“evidence from neuroanatomical, animal, and epidemiologic studies support the prenatal and early postnatal origins of autism.19–24”
From Environmental Chemical Exposures and Autism Spectrum Disorders: A Review of the Epidemiological Evidence (2014) · cites this paper as [23]
In the citing paper
“MIA models have ASD-like social, vocalization, ritualistic, exploration and other behavioral deficits [123–125].”
From The ASD Living Biology: from cell proliferation to clinical phenotype (2019) · cites this paper as [123]
In the citing paper
“it has now been demonstrated through animal models that merely an activated immune response in the mother, absent any infection, is sufficient to lead to changes in the offspring”
From The Role of the Immune System in Autism Spectrum Disorder (2017) · cites this paper as Shi et al, 2003
In the citing paper
“Shi et al (2003) infected two strains of pregnant mice with human influenza virus and observed abnormal behavior, exploration, and social interaction in their offspring.”
From The Role of the Immune System in Autism Spectrum Disorder (2017) · cites this paper as Shi et al, 2003
In the citing paper
“the authors observed similar aberrant phenotypes in the same mice when using only poly(I:C) treatment rather than infection, suggesting that it was the maternal immune response rather than the infection itself that was responsible”
From The Role of the Immune System in Autism Spectrum Disorder (2017) · cites this paper as Shi et al, 2003
In the citing paper
“The consequences of MIA include behavioral deficits of broad relevance to ASD33, 34, 35”
From Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder (2018) · cites this paper as [33]
In the citing paper
“In a mouse model of maternal immune activation, a principal environmental risk factor for autism, mice develop core behavioral features of ASD (impaired social communication and stereotyped behaviors), as well as several neuropathologies and co-morbid gastrointestinal and immunological symptoms relevant to the human disorder (30–32).”
From Emerging Roles for the Gut Microbiome in Autism Spectrum Disorder (2017) · cites this paper as [31]
In the citing paper
“Similarly, mice and/or non-human primates that are exposed to maternal immune activation (MIA) through maternal infection with the viral mimetic, polyinosinic: polycitidylic acid (poly (I:C)), or maternal influenza infection, have offspring that develop abnormal social behaviors 646566, deficits in their immune profiles and anxiety-like phenotypes 67.”
From Gastrointestinal Issues and Autism Spectrum Disorder (2020) · cites this paper as [66]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Koch, M. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00098-7 · Cited by 1,287
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
Mednick, S. A. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800260109013 · Cited by 1,203
A decrease of reelin expression as a putative vulnerability factor in schizophrenia
Impagnatiello, F., Guidotti, A. R., Pesold, C., Dwivedi, Y., Caruncho, H. J., Pisu, M. G., Uzunov, D. P., Smalheiser, N. R., Davis, J. M., Pandey, G. N., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15718 · Cited by 762
Maturation, Activation, and Protection of Dendritic Cells Induced by Double-stranded RNA
Cella, M., Salio, M., Sakakibara, Y., Langen, H., Julkunen, I., & Lanzavecchia, A. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.5.821 · Cited by 709
Malhotra, A. K. (1997) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00036-5 · Cited by 681
Swerdlow, N. R., & Geyer, M. A. (1998) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033326 · Cited by 626
Postmortem brain abnormalities of the glutamate neurotransmitter system in autism
Purcell, A. E., Jeon, O. H., Zimmerman, A. W., Blue, M. E., & Pevsner, J. (2001) · Neurology · doi:10.1212/wnl.57.9.1618 · Cited by 518
Marenco, S., & Weinberger, D. R. (2000) · Development and Psychopathology · doi:10.1017/s0954579400003138 · Cited by 485
Brain anatomy and sensorimotor gating in Asperger's syndrome
McAlonan, G. M. (2002) · Brain · doi:10.1093/brain/awf150 · Cited by 447
Jyonouchi, H., Sun, S., & Le, H. (2001) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(01)00421-0 · Cited by 396
Research works printed but not linked: 1
- Shahab SZ, Glezen WP (1994) Influenza virus. In: Viral diseases in preg- nancy (Gonik B, ed), pp 215-223. New York: Springer.
Cited by
Sorted by citations
Items 701–800 of 996
Animal Models of Chorioamnionitis: Considerations for Translational Medicine
Barjat, T. R., Digonnet, M., Giraud, A., Ayash, T. A., Vancolen, S. Y., Benharouga, M., Chauleur, C., Alfaidy, N., & Sébire, G. (2022) · Biomedicines · doi:10.3390/biomedicines10040811 · Cited by 11
Zhang, J., Yu, J., Zhang, H., Bilkey, D. K., & Liu, P. (2017) · Synapse · doi:10.1002/syn.22011 · Cited by 12
Guha, S. K., Sarkar, I., Patgaonkar, M. S., Banerjee, S., Mukhopadhyay, S., Sharma, S., Pathak, S., & Vaidya, V. A. (2020) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2020.577363 · Cited by 11
Haddad, F. L., Lu, L., Baines, K. J., & Schmid, S. (2020) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2020.100156 · Cited by 13
Tsuda, N., Tohmi, M., Mizuno, M., & Nawa, H. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.07.007 · Cited by 11
Makinodan, M., Tatsumi, K., Okuda, H., Manabe, T., Yamauchi, T., Noriyama, Y., Kishimoto, T., & Wanaka, A. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.09.009 · Cited by 11
Activation of the Maternal Immune System as a Risk Factor for Neuropsychiatric Disorders
Smith, S. E. P., Hsiao, E. Y., & Patterson, P. H. (2010) · Springer eBooks · doi:10.1007/978-1-60327-921-5_7 · Cited by 12
Self-citationBoksa, P., & Luheshi, G. N. (2003) · Clinical Neuroscience Research · doi:10.1016/j.cnr.2003.10.018 · Cited by 11
Influenza Infection During Pregnancy and Risk of Seizures in Offspring
Lee, Y.-F., Lin, Y.-H., Lin, C., & Lin, M. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.34935 · Cited by 10
Grigoryan, G. A., & Gulyaeva, N. V. (2016) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-016-0386-7 · Cited by 13
Mackus, M., de Kruijff, D., Otten, L. S., Kraneveld, A. D., Garssen, J., & Verster, J. C. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph14040409 · Cited by 10
GWAS, Cytomegalovirus Infection, and Schizophrenia
Grove, J., Børglum, A. D., & Pearce, B. D. (2014) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-014-0022-1 · Cited by 10
Potential microbial origins of schizophrenia and their treatments
Fatemi, S. H. (2009) · Drugs of today · doi:10.1358/dot.2009.045.004.1353924 · Cited by 10
Self-citationImpact of Prenatal Immune System Disturbances on Brain Development
Madhusudan, A., Vogel, P., & Knuesel, I. (2012) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-012-9374-z · Cited by 11
Tasker, R. A., Marriott, A. L., & Shaw, C. A. (2010) · The EPMA Journal · doi:10.1007/s13167-010-0019-0 · Cited by 10
Costa, B., Gouveia, M. J., & Vale, N. (2024) · Vaccines · doi:10.3390/vaccines12070782 · Cited by 9
Saunders, J. M., Muguruza, C., Sierra, S., Moreno, J. L., Callado, L. F., Meana, J. J., Beardsley, P. M., & González‐Maeso, J. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102481 · Cited by 9
Makinodan, M., Yamauchi, T., Tatsumi, K., Okuda, H., Noriyama, Y., Sadamatsu, M., Kishimoto, T., & Wanaka, A. (2009) · Journal of brain disease · doi:10.4137/jcnsd.s2255 · Cited by 9
Douma, T. N., Kolarz, A., Postma, Y., Olivier, B., & Groenink, L. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.07.032 · Cited by 9
C1q as a Regulator of Brain Development: Implications for Autism Spectrum Disorders
Tan, C. F. J. (2015) · Brain Disorders & Therapy · doi:10.4172/2168-975x.1000152 · Cited by 10
The effect of schizophrenia risk factors on mismatch responses in a rat model
Jalewa, J., Todd, J., Michie, P. T., Hodgson, D. M., & Harms, L. R. (2022) · Psychophysiology · doi:10.1111/psyp.14175 · Cited by 9
Herbert, M. R., & Anderson, M. P. (2008) · Cited by 9
Immune Modulatory Treatments for Autism Spectrum Disorder
Thom, R. P., & McDougle, C. J. (2020) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2020.100836 · Cited by 9
Unravelling the Viral Hypothesis of Schizophrenia: A Comprehensive Review of Mechanisms and Evidence
Sighencea, M. G., & Trifu, S. C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157429 · Cited by 9
Social Behavior Testing in Mice: Social Interest, Recognition, and Aggression
Clipperton‐Allen, A. E., & Page, D. T. (2022) · Neuromethods · doi:10.1007/978-1-0716-2748-8_14 · Cited by 8
Can Neuroinflammation Influence the Development of Autism Spectrum Disorders
Pardo-Villamizar, C. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-489-0_15 · Cited by 9
Folsom, T. D., & Fatemi, S. H. (2010) · Advances in neurobiology · doi:10.1007/978-1-4419-7104-3_13 · Cited by 9
Self-citationMoe, A. A. K., Scott, J. G., Burne, T. H. J., & Eyles, D. W. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116654776 · Cited by 8
Dendrites in Autism Spectrum Disorders
Martínez‐Cerdeño, V., Maezawa, I., & Jin, L. (2016) · Springer eBooks · doi:10.1007/978-4-431-56050-0_20 · Cited by 8
Guo, Z., Tse, Y. C., Zhang, Y., Sun, Q., Vecchiarelli, H. A., Aukema, R. J., Hill, M. N., Wong, T. P., & Boksa, P. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.09.003 · Cited by 9
Zhang, H., Hu, S., Qu, S.-T., Lv, M., Wang, J., Liu, X.-T., Yao, J.-H., Ding, Y., & Xu, G. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46030121 · Cited by 8
Autism and Parkinson's Disease: Animal Models and a Common Etiological Mechanism
Yochum, C. L. (2009) · The Chinese Journal of Physiology · doi:10.4077/cjp.2009.amh081 · Cited by 8
Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder
Hill‐Yardin, E. L., McKeown, S. J., Novarino, G., & Grabrucker, A. M. (2017) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-319-52498-6_9 · Cited by 8
Melnik, A., Tauber, S., Dumrese, C., Ullrich, O., & Wolf, S. A. (2012) · European Journal of Microbiology and Immunology · doi:10.1556/eujmi.2.2012.3.10 · Cited by 7
Detection of abnormal behaviors in prenatal Poly(I:C) exposed mice in a group‐rearing environment
Komada, M., Kiriyama, N., Sugiyama, R., Harada, K., & Kawashita, N. (2024) · Congenital Anomalies · doi:10.1111/cga.12563 · Cited by 7
Davis, L. K., Ince, L. M., Gullapalli, S., & Fonken, L. K. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.03.005 · Cited by 7
Effects of iTBS-rTMS on the Behavioral Phenotype of a Rat Model of Maternal Immune Activation
Rittweger, N., Ishorst, T., Barmashenko, G., Aliane, V., Winter, C., & Funke, K. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.670699 · Cited by 7
Microglia and microbiome in schizophrenia: can immunomodulation improve symptoms?
Juckel, G., & Freund, N. (2023) · Journal of Neural Transmission · doi:10.1007/s00702-023-02605-w · Cited by 7
Liong, S., Miles, M. A., Mohsenipour, M., Liong, F., Hill‐Yardin, E. L., & Selemidis, S. (2023) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00062.2023 · Cited by 7
Adiponectin blood levels and autism spectrum disorders: a systematic review
Ali, M., Kamran, M., Talha, M., & Shad, M. U. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-05529-1 · Cited by 8
O uso de ácido valproico para a indução de modelos animais de autismo: uma revisão
Schlickmann, E., & Fortunato, J. J. (2013) · Jornal Brasileiro de Psiquiatria · doi:10.1590/s0047-20852013000200009 · Cited by 7
Fatemi, S. H. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2009.09.011 · Cited by 7
Self-citationYu, J. (2010) · The Open Behavioral Science Journal · doi:10.2174/1874230001004010009 · Cited by 6
Brown, A. M., Conn, I., Boerrigter, D., Weickert, C. S., & Purves-Tyson, T. D. (2022) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2022.577813 · Cited by 7
Interleukin 15 modulates the effects of poly I:C maternal immune activation on offspring behaviour
Haddad, F. L., Patel, S. V., Doornaert, E. E., Oliveira, C. D., Allman, B. L., Baines, K. J., Renaud, S. J., & Schmid, S. (2022) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2022.100473 · Cited by 8
Noel, S. C., Fortin-Hamel, L., Haque, M., & Scott, M. E. (2022) · Scientific Reports · doi:10.1038/s41598-022-13971-y · Cited by 8
Kim, A. J. H., Zisman, C. R., & Holingue, C. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_371 · Cited by 7
Cristancho, A. G., Tulina, N. M., Brown, A. G., Anton, L., Barila, G., & Elovitz, M. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010032 · Cited by 8
Linking Stress and Schizophrenia: A Focus on Prepulse Inhibition
Douma, T. N., Millan, M. J., Olivier, B., & Groenink, L. (2011) · InTech eBooks · doi:10.5772/26944 · Cited by 6
Pro-Inflammatory Phenotype Induced by Maternal Immune Stimulation During Pregnancy
Nicholas, M., Mandal, M., Elkabes, S., Zhang, P., Sadoshima, J., Basak, S., Zhai, P., & DONNELLY, R. J. (2013) · InTech eBooks · doi:10.5772/53990 · Cited by 7
Neuroinflammation in Animal Models of Autism
Kazlauskas, N., Robinson‐Agramonte, M. D. L. Á., & Depino, A. M. (2015) · Springer eBooks · doi:10.1007/978-3-319-16321-5_8 · Cited by 7
Expression and Action of Cytokines in the Brain: Mechanisms and Pathophysiological Implications
Dantzer, R. (2007) · Elsevier eBooks · doi:10.1016/b978-012088576-3/50018-6 · Cited by 7
Malouf, C., & Ottersbach, K. (2019) · Experimental Hematology · doi:10.1016/j.exphem.2019.07.004 · Cited by 7
Namba, H., & Nawa, H. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.06.003 · Cited by 7
Easson, A. K., & Woodbury‐Smith, M. (2014) · Research in Autism · doi:10.1016/j.rasd.2013.12.007 · Cited by 7
The Role of Neurodevelopmental Genes in Infectious Etiology of Autism
Fatemi, S. H. (2008) · American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology · doi:10.3844/ajbbsp.2008.177.182 · Cited by 7
Self-citationAlteration of Neurodevelopment and behavior by Maternal Immune Activation
Smith, S. E. P., & Patterson, P. H. (2008) · Springer eBooks · doi:10.1007/978-0-387-84851-8_7 · Cited by 7
Self-citationChauhan, V. P. S., & Chauhan, A. (2014) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-1-4939-0440-2_4 · Cited by 7
The developmental environment: influences on subsequent cognitive function and behaviour
Landon, J., Davison, M., & Breier, B. H. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511544699.028 · Cited by 7
Animal models in autism research: The legacy of Paul H. Patterson
Pardo, C. A., & Meffert, M. K. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.11.004 · Cited by 7
(2003) · Nature Neuroscience · doi:10.1038/nn0403-323 · Cited by 7
Liong, S., Choy, K. H. C., Luca, S. N. D., Liong, F., Coward‐Smith, M., Oseghale, O., Miles, M. A., Vlahos, R., Valant, C., Nithianantharajah, J., et al. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.06.025 · Cited by 6
Improving the odds of survival: transgenerational effects of infections
Spanou, V. M., Andriopoulou, T., Giamarellos‐Bourboulis, E. J., & Netea, M. G. (2025) · EMBO Molecular Medicine · doi:10.1038/s44321-025-00192-9 · Cited by 7
Taskiran, S. Y., Taşkıran, M., Ünal, G., & Gölgeli, A. (2023) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2023.173593 · Cited by 6
Maroon, M., Haddad, F. L., Doornaert, E. E., Allman, B. L., & Schmid, S. (2024) · PLoS ONE · doi:10.1371/journal.pone.0299380 · Cited by 6
Li, W., Sun, F., Guo, X., Hu, Y., Ding, S., Ding, M., Song, M., Shao, M., Yang, Y., Guo, W., et al. (2020) · Physiology & Behavior · doi:10.1016/j.physbeh.2020.112805 · Cited by 6
Bagheri, F., Safari, A., & Namavar, M. R. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113581 · Cited by 6
Autism: genetics, environmental stressors, maternal immune activation, and the male bias in autism
Otaru, S., & Lawrence, D. A. (2022) · Exploration of Neuroprotective Therapy · doi:10.37349/ent.2022.00025 · Cited by 7
Zucker, E., & Burd, I. D. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114207 · Cited by 6
Brown, E. C., Taş, C., Gonzalez, C., & Brüne, M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405172-0.00001-6 · Cited by 6
Gil-Pisa, I., Cebrián, C., Ortega, J. E., Meana, J. J., & Sulzer, D. L. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-128 · Cited by 6
Schizophrenia Pharmacology: Past, Present, and Future Targets for Intervention
Cronenwett, W. J. (2016) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.20160009 · Cited by 7
Advances in Causes and Treatment of Autism
XiaoLi, W. U., Jin, F., & Duan, Y. (2015) · Scientia Sinica Vitae · doi:10.1360/n052015-0108 · Cited by 5
Brymer, K. J., Kulhaway, E. Y., Howland, J. G., Caruncho, H. J., & Kalynchuk, L. E. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113291 · Cited by 6
Inflammation and Neuroimmunity in the Pathogenesis of Autism
Pardo‐Villamizar, C., & Zimmerman, A. W. (2009) · CRC Press eBooks · doi:10.1201/9781420068870-c12 · Cited by 6
Infantile Cerebellar Pilocytic Astrocytoma with Autism Spectrum Disorder
Adachi, K., Murai, Y., & Teramoto, A. (2012) · Journal of Nippon Medical School · doi:10.1272/jnms.79.228 · Cited by 6
From Viral Infections to Autistic Neurodevelopmental Disorders via Cross-Reactivity
Kanduc, D., & Polito, A. N. (2018) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20180014 · Cited by 6
Heuer, L. S., Ashwood, P., & de Water, J. V. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-489-0_12 · Cited by 6
Understanding Barrier Mechanisms In the Developing Brain To Aid Therapy For the Dysfunctional Brain
Saunders, N. R., & Habgood, M. D. (2011) · Future Neurology · doi:10.2217/fnl.10.84 · Cited by 6
Environmental Factors and Limbic Vulnerability in Childhood Autism
Lathe, R. (2008) · American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology · doi:10.3844/ajbbsp.2008.183.197 · Cited by 6
Bortolato, M., & Godar, S. C. (2010) · Interdisciplinary Perspectives on Infectious Diseases · doi:10.1155/2010/380456 · Cited by 7
Influenza Vaccine Programs and Pregnancy: A Need for More Evidence
MacDonald, N. E., McNeil, S., Allen, V. M., Scott, J., & Dodds, L. A. (2004) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)30416-9 · Cited by 6
Modeling Features of Autism in Animals
Patterson, P. H. (2006) · CRC Press eBooks · doi:10.1201/9781420004205-18 · Cited by 6
Self-citationCritical Age Windows for Neurodevelopmental Psychiatric Disorders: Evidence from Animal Models
Marco, E. M., Macrì, S., & Laviola, G. (2010) · Springer eBooks · doi:10.1007/978-1-4614-0785-0_26 · Cited by 7
An Expanding Spectrum of Autism Models
Herbert, M. R., & Anderson, M. P. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-489-0_20 · Cited by 6
Ketamina: Nuevas observaciones sobre su consumo, consumidores y efectos
Jansen, K. L. R., & Theron, L. (2003) · Adicciones · doi:10.20882/adicciones.458 · Cited by 6
The Role of Reelin in Etiology and Treatment of Psychiatric Disorders
Fatemi, S. H., Reutiman, T. J., & Folsom, T. D. (2008) · Springer eBooks · doi:10.1007/978-0-387-76761-1_22 · Cited by 6
Self-citationEstes, M. L., Farrelly, K., Cameron, S., Aboubechara, J. P., Haapanen, L. A. D., Schauer, J. D., Horta, A., Prendergast, K., MacMahon, J. A., Shaffer, C. I., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/699983 · Cited by 4
Neuroimmune Mechanisms of Neurodevelopmental Disorders
Anderson, S., Jin, R. M., & Molofsky, A. V. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.10.023 · Cited by 4
SARS-CoV-2 infection during pregnancy and neurodevelopmental outcomes in early childhood
Croen, L., Qian, Y., Grosvenor, L. P., Alexeeff, S., Yolken, R. H., Ames, J., Ashwood, P., Kim, D. H. J., & de Water, J. V. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-03818-9 · Cited by 6
Park, H.-Y., Yu, J. E., Kim, S., Nahm, S., & Chung, C. (2015) · Scientific Reports · doi:10.1038/srep13440 · Cited by 5
Developmental Immune Activation Models with Relevance to Schizophrenia
Meyer, U. (2015) · Current topics in neurotoxicity · doi:10.1007/978-3-319-13602-8_2 · Cited by 6
COVID-19 and Women's Health: A Low- and Middle-Income Country Perspective
Premji, S., Shaikh, K., Lalani, S. B., Yim, I. S., Moore, S. R., Ali, N. A., Aijaz, S., & Letourneau, N. L. (2020) · Frontiers in Global Women s Health · doi:10.3389/fgwh.2020.572158 · Cited by 5
Schaub, N., Ammann, N., Conring, F., Müller, T., Federspiel, A., Wiest, R., Hoepner, R., Stegmayer, K., & Walther, S. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.877461 · Cited by 6
Puljević, M., Daniłowicz-Szymanowicz, L., Molon, G., Puljević, D., Raczak, G., Canali, G., Velagić, V., Pezo-Nikolić, B., & Miličić, D. (2018) · Annals of Noninvasive Electrocardiology · doi:10.1111/anec.12610 · Cited by 3
Interaction of maternal immune activation and genetic interneuronal inhibition
Anderson, A. C., Genaro‐Mattos, T. C., Allen, L. B., Koczok, K., Korade, Ž., & Mirnics, K. (2021) · Brain Research · doi:10.1016/j.brainres.2021.147370 · Cited by 5
Gottschalk, M. G., Sarnyai, Z., Guest, P. C., Harris, L. W., & Bahn, S. (2012) · Archives of Clinical Psychiatry (São Paulo) · doi:10.1590/s0101-60832012005000007 · Cited by 5
Bauman, M. D., Crawley, J. N., & Berman, R. F. (2010) · Wiley eBooks · doi:10.1002/9780470015902.a0022368 · Cited by 5
Viral Infections and Temporal Programming of Autism Spectrum Disorders in the Mother's Womb
Jash, S., & Sharma, S. (2022) · Frontiers in Virology · doi:10.3389/fviro.2022.863202 · Cited by 4
Neuroinflammation and autism: what have we learned so far?
Aytulun, A., & Ünal, D. (2024) · International Journal of Developmental Disabilities · doi:10.1080/20473869.2024.2366722 · Cited by 5
Metadata
- Authors
- Shi, L., Fatemi, S. H., Sidwell, R. W., & Patterson, P. H.
- Affiliations
- California Institute of Technology (US)
- University of Minnesota (US)
- Utah State University (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2003-01-01
- Volume
- 23
- Issue
- 1
- Pages
- 297-302
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6742135
- OpenAlex
- W2143217444
- Cited by
- 1,025
- References
- 43
- Citations by year
- 2026: 10 · 2025: 15 · 2024: 34 · 2023: 29 · 2022: 48 · 2021: 45 · 2020: 42 · 2019: 35 · 2018: 47 · 2017: 46 · 2016: 47 · 2015: 59 · 2014: 57 · 2013: 57 · 2012: 66
- FWCI
- 11.69
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neuroscience (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion, cc-by)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- National Institutes of Health (n01ai065291-009)
- National Institute of Allergy and Infectious Diseases (N01 AI 65291)
- Topics
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- maternal influenza infection, prenatal viral infection, offspring behavior, prepulse inhibition, acoustic startle response, clozapine, chlorpromazine, ketamine, exploratory behavior, social interaction deficits, maternal immune response, polyinosinic-polycytidylic acid, schizophrenia, autism spectrum disorder, mouse strain differences
- MeSH terms
- Acoustic Stimulation, Animals, Animals, Newborn, Antiviral Agents, Anxiety, Behavior, Animal, Chlorpromazine, Clozapine, Exploratory Behavior, Female, Immunity, Ketamine, Mice, Inbred BALB C, Mice, Inbred C57BL, Motor Activity, Orthomyxoviridae Infections, Poly I-C, Pregnancy, Social Behavior, Antipsychotic Agents, Maternal-Fetal Relations, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
