Forebrain-Specific Neuronal Inhibition of Nuclear Factor-κB Activity Leads to Loss of Neuroprotection

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Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

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Strong Evidence That KIAA0319 on Chromosome 6p Is a Susceptibility Gene for Developmental Dyslexia

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NF-κB as an Inducible Regulator of Inflammation in the Central Nervous System

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NF-κB Regulates Spatial Memory Formation and Synaptic Plasticity through Protein Kinase A/CREB Signaling

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Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling

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Neuronal Activation of NF-κB Contributes to Cell Death in Cerebral Ischemia

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Increased Mitochondrial Calcium Sensitivity and Abnormal Expression of Innate Immunity Genes Precede Dopaminergic Defects in Pink1-Deficient Mice

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NF-κB as a therapeutic target in neurodegenerative diseases

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NF-κB signalling regulates the growth of neural processes in the developing PNS and CNS

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Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology

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NF‐κB pathway: a target for preventing β‐amyloid (Aβ)‐induced neuronal damage and Aβ42 production

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Inactivation of astroglial NF‐κB promotes survival of retinal neurons following ischemic injury

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Bim and Noxa Are Candidates to Mediate the Deleterious Effect of the NF-κB Subunit RelA in Cerebral Ischemia

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IκB Kinase/Nuclear Factor κB-Dependent Insulin-Like Growth Factor 2 (Igf2) Expression Regulates Synapse Formation and Spine Maturation via Igf2 Receptor Signaling

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NF-κB Signaling Pathways

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Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

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Mechanisms of DNA damage-mediated neurotoxicity in neurodegenerative disease

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Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: From genes to phenotype.

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TLR4 and CD14 receptors expressed in rat pineal gland trigger NFKB pathway

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Strong Neuroprotection by Inhibition of NF-κB After Neonatal Hypoxia-Ischemia Involves Apoptotic Mechanisms but Is Independent of Cytokines

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Sp1 Is Up-regulated in Cellular and Transgenic Models of Huntington Disease, and Its Reduction Is Neuroprotective

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NF-KappaB in Long-Term Memory and Structural Plasticity in the Adult Mammalian Brain

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NF-κB/Rel Regulates Inhibitory and Excitatory Neuronal Function and Synaptic Plasticity

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Lentiviral-mediated Targeted NF-κB Blockade in Dorsal Spinal Cord Glia Attenuates Sciatic Nerve Injury–induced Neuropathic Pain in the Rat

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NF-κB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid β-peptide toxicity

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NF-κB p50-deficient mice show reduced anxiety-like behaviors in tests of exploratory drive and anxiety

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The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus

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Chapter 24 NF‐KappaB Dimers in the Regulation of Neuronal Survival

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Minimal NF-κB activity in neurons

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Association of NFKB1, which encodes a subunit of the transcription factor NF- B, with alcohol dependence

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Huntingtin and the Synapse

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Pyrrolidine dithiocarbamate inhibits translocation of nuclear factor kappa‐B in neurons and protects against brain ischaemia with a wide therapeutic time window

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Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration

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Transcriptional control of maladaptive and protective responses in alcoholics: A role of the NF-κB system

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Oxidative Stress Activates Transcription Factor NF-kB-Mediated Protective Signaling in Primary Rat Neuronal Cultures

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Astroglial Inhibition of NF-κB Does Not Ameliorate Disease Onset and Progression in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)

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The Role of NF-κB Triggered Inflammation in Cerebral Ischemia

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Regrowing the Adult Brain: NF-κB Controls Functional Circuit Formation and Tissue Homeostasis in the Dentate Gyrus

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Functional mechanism of neuroprotection by inhibitors of type B monoamine oxidase in Parkinson’s disease

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FLIPL Protects Neurons against In Vivo Ischemia and In Vitro Glucose Deprivation-Induced Cell Death

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NFκB signaling regulates embryonic and adult neurogenesis

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The Role of NF-κB in Neuroinflammation

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Post‐ischemic brain damage: NF‐κB dimer heterogeneity as a molecular determinant of neuron vulnerability

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Selectively increased sensitivity of cerebellar granule cells to AMPA receptor-mediated excitotoxicity in a mouse model of Batten disease

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Intrahippocampal injection of Aβ 1-42 inhibits neurogenesis and down-regulates IFN-γ and NF-κB expression in hippocampus of adult mouse brain

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Activation of Nuclear Factor-κB in the Brain after Experimental Subarachnoid Hemorrhage and Its Potential Role in Delayed Brain Injury

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Perinatal brain injury and regulation of transcription

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Translational and transcriptional control of Sp1 against ischaemia through a hydrogen peroxide-activated internal ribosomal entry site pathway

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Unique aspects of transcriptional regulation in neurons - nuances in NFkappaB and Sp1-related factors

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NFκB in neurons? The Uncertainty Principle in neurobiology

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Coincident enrichment of phosphorylated IκBα, activated IKK, and phosphorylated p65 in the axon initial segment of neurons

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Nuclear Factor-κB Activation in Axons and Schwann Cells in Experimental Sciatic Nerve Injury and Its Role in Modulating Axon Regeneration: Studies With Etanercept

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Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth

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Estrogen Neuroprotection Against the Neurotoxic Effects of Ethanol Withdrawal: Potential Mechanisms

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Intranasal nerve growth factor attenuates tau phosphorylation in brain after traumatic brain injury in rats

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The Characteristic Long-Term Upregulation of Hippocampal NF-κB Complex in PTSD-Like Behavioral Stress Response Is Normalized by High-Dose Corticosterone and Pyrrolidine Dithiocarbamate Administered Immediately after Exposure

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Prolyl 4-hydroxylase activity-responsive transcription factors: From hydroxylation to gene expression and neuroprotection

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IKKβ Deficiency in Myeloid Cells Ameliorates Alzheimer's Disease-Related Symptoms and Pathology

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IκBα deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery

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NF-kB/NOS cross-talk induced by mitochondrial complex II inhibition: Implications for Huntington's disease

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Involvement of Nuclear Factor-κB in Inflammation and Neuronal Plasticity Associated with Post-Traumatic Stress Disorder

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The regulating effect of curcumin on NF-κB pathway in neurodegenerative diseases: a review of the underlying mechanisms

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Human Umbilical Cord Blood Cells Protect Oligodendrocytes from Brain Ischemia through Akt Signal Transduction

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The Power of Reversibility

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Roles of HIF-1α, VEGF, and NF-κB in Ischemic Preconditioning-Mediated Neuroprotection of Hippocampal CA1 Pyramidal Neurons Against a Subsequent Transient Cerebral Ischemia

Lee, J., Tae, H., Kim, I. H., Cho, J.-H., Lee, T.-K., Park, J. H., Ahn, J. H., Choi, S. Y., Bai, H. C., Shin, B.-N., et al. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0219-2 · Cited by 41

Activation of NF-κB in the mouse spinal cord following sciatic nerve transection

Pollock, G. A., Pennypacker, K. R., Mémet, S., Israël, A., & Saporta, S. (2005) · Experimental Brain Research · doi:10.1007/s00221-005-2318-6 · Cited by 42

Differential contributions of microglial and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice

Kyrargyri, V., Vega‐Flores, G., Gruart, A., Delgado-Garcia, J. M., & Probert, L. (2014) · Glia · doi:10.1002/glia.22756 · Cited by 44

Neuronal IκB Kinase β Protects Mice from Autoimmune Encephalomyelitis by Mediating Neuroprotective and Immunosuppressive Effects in the Central Nervous System

Emmanouil, M., Taoufik, E., Tseveleki, V., Vamvakas, S. M., Tselios, T. V., Karin, M., Lassmann, H., & Probert, L. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900834 · Cited by 39

Hormesis: A promising strategy to sustain endogenous neuronal survival pathways against neurodegenerative disorders

Marini, A. M., Jiang, H., Pan, H., Wu, X., & Lipsky, R. H. (2007) · Ageing Research Reviews · doi:10.1016/j.arr.2007.07.003 · Cited by 38

Differential expression of BDNF mRNA splice variants in mouse brain and immune cells

Kruse, N., Cetin, S., Chan, A., Gold, R., & Lühder, F. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.09.001 · Cited by 40

Defensive effect of natrium diethyldithiocarbamate trihydrate (NDDCT) and lisinopril in DOCA–salt hypertension-induced vascular dementia in rats

Sharma, B., & Singh, N. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2718-9 · Cited by 36

Transcriptional Dysregulation in Huntington’s Disease: The Role in Pathogenesis and Potency for Pharmacological Targeting

Pogoda-Wesołowska, A., Chmielewska, N., Maciejak, P., & Szyndler, J. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666200705225821 · Cited by 38

GAL4–NF-κB Fusion Protein Augments Transgene Expression from Neuronal Promoters in the Rat Brain

Liu, B. H., Yang, Y., Paton, J. F. R., Li, F., Boulaire, J., Kasparov, S., & Wang, S. (2006) · Molecular Therapy · doi:10.1016/j.ymthe.2006.05.020 · Cited by 36

NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells

Ferlazzo, N., Condello, S., Currò, M., Parisi, G., Ientile, R., & Caccamo, D. (2008) · BMC Neuroscience · doi:10.1186/1471-2202-9-62 · Cited by 37

Regional, cellular and species difference of two key neuroinflammatory genes implicated in schizophrenia

Murphy, C. E., Kondo, Y., Walker, A. K., Rothmond, D. A., Matsumoto, M., & Weickert, C. S. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.05.055 · Cited by 35

The involvement of NF-κB p65/p52 in the effects of GDNF on DA neurons in early PD rats

Cao, J. P., Wang, H. J., Yu, J., Liu, H. M., & Gao, D. (2008) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2008.03.007 · Cited by 35

Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-κB signaling in neurons

König, H., Fenner, B. J., Byrne, J. C., Schwamborn, R., Bernaś, T., Jefferies, C. A., & Prehn, J. H. M. (2012) · Journal of Cell Science · doi:10.1242/jcs.111880 · Cited by 34

Mechanism of NF‐κB inactivation induced by survival signal withdrawal in cerebellar granule neurons

D. Kovács, A., Chakraborty‐Sett, S., Ramirez, S. H., Sniderhan, L. F., Williamson, A. L., & Maggirwar, S. B. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03493.x · Cited by 32

Decoding signaling pathways involved in prolactin-induced neuroprotection: A review

Molina-Salinas, G., Rivero-Segura, N. A., Cabrera-Reyes, E. A., Rodríguez-Chávez, V., Langley, E., & Cerbón, M. A. (2021) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2021.100913 · Cited by 33

ROS-Production–Mediated Activation of AP-1 but Not NFκB Inhibits Glutamate-Induced HT4 Neuronal Cell Death

Aharoni-Simon, M., Reifen, R. M., & Tirosh, O. (2006) · Antioxidants and Redox Signaling · doi:10.1089/ars.2006.8.1339 · Cited by 31

Nuclear factor‐κb activation is associated with glutamate‐evoked tissue transglutaminase up‐regulation in primary astrocyte cultures

Caccamo, D., Campisi, A., Currò, M., Aguennouz, M., Volti, G. L., Avola, R., & Ientile, R. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20683 · Cited by 30

Upregulation of CX3CL1 mediated by NF-κB activation in dorsal root ganglion contributes to peripheral sensitization and chronic pain induced by oxaliplatin administration

Wang, J., Zhang, X., Tao, R., Zhang, J., Liu, L., Jiang, Y., Ma, S.-H., Lin-xia, S., & Xia, L. (2017) · Molecular Pain · doi:10.1177/1744806917726256 · Cited by 30

Low K + Promotes NF-κB/DNA Binding in Neuronal Apoptosis Induced by K + Loss

Tao, Y., Yan, D., Yang, Q., Zeng, R., & Wang, Y. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.3.1038-1050.2006 · Cited by 30

Constitutive Nuclear Factor-κB Activity Is Required for Central Neuron Survival

Bhakar, A. L., Tannis, L.-L., Zeindler, C., Russo, M. P., Jobin, C., Park, D. S., MacPherson, S., & Barker, P. A. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-19-08466.2002 · Cited by 310

NFκB‐inducing kinase inhibits NFκB activity specifically in neurons of the CNS

Mao, X. R., Phanavanh, B., Hamdan, H., Moerman-Herzog, A. M., & Barger, S. W. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13526 · Cited by 15

Role of nuclear factor kappaB in the central nervous system.

Małek, R., Borowicz, K. K., Jargiello, M., & Czuczwar, S. J. (2007) · PubMed · Cited by 82

Forebrain-specific neuronal inhibition of nuclear factor-kappaB activity leads to loss of neuroprotection

Fridmacher, V., Kaltschmidt, B., Goudeau, B., Ndiaye, D., Rossi, F. M., Pfeiffer, J., Kaltschmidt, C., Israël, A., & Memet, S. (2003) · PUB – Publications at Bielefeld University (Bielefeld University) · Cited by 5

Specific Deficiency in Nuclear Factor-κB Activation in Neurons of the Central Nervous System

Jarosinski, K. W., Whitney, L. W., & Massa, P. T. (2001) · Laboratory Investigation · doi:10.1038/labinvest.3780341 · Cited by 22