The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Redox regulation of plant stem cell fate
Open accessAbstract
Despite the importance of stem cells in plant and animal development, the common mechanisms of stem cell maintenance in both systems have remained elusive. Recently, the importance of hydrogen peroxide (H 2 O 2 ) signaling in priming stem cell differentiation has been extensively studied in animals. Here, we show that different forms of reactive oxygen species ( ROS ) have antagonistic roles in plant stem cell regulation, which were established by distinct spatiotemporal patterns of ROS ‐metabolizing enzymes. The superoxide anion ( ) is markedly enriched in stem cells to activate WUSCHEL and maintain stemness, whereas H 2 O 2 is more abundant in the differentiating peripheral zone to promote stem cell differentiation. Moreover, H 2 O 2 negatively regulates biosynthesis in stem cells, and increasing H 2 O 2 levels or scavenging leads to the termination of stem cells. Our results provide a mechanistic framework for ROS ‐mediated control of plant stem cell fate and demonstrate that the balance between and H 2 O 2 is key to stem cell maintenance and differentiation.
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Reddy, G. V., Heisler, M. G., Ehrhardt, D. W., & Meyerowitz, E. M. (2004) · Development · doi:10.1242/dev.01261 · Cited by 339
Hamanaka, R. B., Glasauer, A., Hoover, P., Yang, S., Blatt, H., Mullen, A. R., Getsios, S., Gottardi, C. J., DeBerardinis, R. J., Lavker, R. M., et al. (2013) · Science Signaling · doi:10.1126/scisignal.2003638 · Cited by 315
The Stem Cell Niche in Leaf Axils Is Established by Auxin and Cytokinin in Arabidopsis
Wang, Y., Wang, J., Shi, B., Yu, T., Qi, J., Meyerowitz, E. M., & Jiao, Y. (2014) · The Plant Cell · doi:10.1105/tpc.114.123083 · Cited by 207
Cited by
Mechanisms of ROS Regulation of Plant Development and Stress Responses
Huang, H., Ullah, F., Zhou, D.-X., Yi, M., & Zhao, Y. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.00800 · Cited by 1,468
Reactive oxygen species in plant development
Mhamdi, A., & Van Breusegem, F. (2018) · Development · doi:10.1242/dev.164376 · Cited by 667
Nitric oxide controls shoot meristem activity via regulation of DNA methylation
Zeng, J., Zhao, X., Liang, Z., Hidalgo, I., Gebert, M., Fan, P., Wenzl, C., Gornik, S. G., & Lohmann, J. U. (2023) · Nature Communications · doi:10.1038/s41467-023-43705-1 · Cited by 36
Self-citation
Metadata
- Authors
- Zeng, J., Dong, Z., Wu, H., Tian, Z., & Zhao, Z.
- Venue
- The EMBO Journal
- Published
- 2017-08-24
- Volume
- 36
- Issue
- 19
- Pages
- 2844-2855
- ISSN
- 0261-4189 (ISSN-L)
- 1460-2075
- OpenAlex
- W2746238379
- Cited by
- 273
- References
- 3
- FWCI
- 13.07
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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