MYC and tumor metabolism: chicken and egg

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009) · Science · doi:10.1126/science.1160809 · Cited by 16,197

The Warburg Effect: How Does it Benefit Cancer Cells?

Liberti, M. V., & Locasale, J. W. (2016) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.12.001 · Cited by 5,150

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., & Thompson, C. B. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.002 · Cited by 4,088

MYC on the Path to Cancer

Dang, C. V. (2012) · Cell · doi:10.1016/j.cell.2012.03.003 · Cited by 3,390

Endoplasmic reticulum stress: cell life and death decisions

Xu, C. (2005) · Journal of Clinical Investigation · doi:10.1172/jci26373 · Cited by 2,291

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

Wang, R., Dillon, C. P., Shi, L. Z., Milasta, S., Carter, R., Finkelstein, D., McCormick, L. L., Fitzgerald, P., Chi, H., Munger, J., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.09.021 · Cited by 2,140 · cited 2×

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

Castello, A., Fischer, B., Eichelbaum, K., Horos, R., Beckmann, B. M., Strein, C., Davey, N. E., Humphreys, D. T., Preiss, T., Steinmetz, L. M., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.031 · Cited by 2,132

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Gao, P., Tchernyshyov, I., Chang, T.-C., Lee, Y.-S., Kita, K., Ochi, T., Zeller, K. I., De Marzo, A. M., Van Eyk, J. E., Mendell, J. T., et al. (2009) · Nature · doi:10.1038/nature07823 · Cited by 2,124

Directly targeting c-Myc contributes to the anti-multiple myeloma effect of anlotinib

Cao, Y., Shan, H., Liu, M., Liu, J., Zhang, Z., Xu, X., Liu, Y., Xu, H., Lei, H., Yu, M., et al. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03685-w · Cited by 21

Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc

Wang, Y., Ruan, D., Wang, Z., Yu, K., Rong, D., Liu, Z., Wang, F., Hu, J., Jin, Y., Wu, Q., et al. (2022) · Oncogene · doi:10.1038/s41388-022-02515-3 · Cited by 20

USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2

Liu, Q., Sheng, W., Ma, Y., Zhen, J., Roy, S., Jafar, C. A., Xin, W., & Wan, Q. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.03.043 · Cited by 20

CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis

Mo, X., Shen, X., Mo, X., Yu, F., Tan, W., Deng, Z., He, J., Luo, Z., Chen, Z., & Yang, J. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115446 · Cited by 19

β-Catenin regulates ovarian granulosa cell cycle and proliferation in laying hens by interacting with TCF4

Ma, X., Han, X., Wang, W., Zhang, Q., & Tang, H. (2023) · Poultry Science · doi:10.1016/j.psj.2023.103377 · Cited by 19

Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression

Liu, L., Lei, B., Wang, L., Chang, C., Yang, H., Liu, J., Huang, G., & Xie, W. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s207211 · Cited by 19

miR-142-5p and miR-212-5p cooperatively inhibit the proliferation and collagen formation of cardiac fibroblasts by regulating c-Myc/TP53INP1

Wang, Z., Fu, M., & Li, Y. (2020) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2019-0495 · Cited by 19

Insights about MYC and Apoptosis in B-Lymphomagenesis: An Update from Murine Models

Vecchio, E., Fiume, G., Correnti, S., Romano, S., Iaccino, E., Mimmi, S., Maisano, D., Nisticò, N., & Quinto, I. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21124265 · Cited by 19

CDK7 Inhibitor THZ1 Induces the Cell Apoptosis of B-Cell Acute Lymphocytic Leukemia by Perturbing Cellular Metabolism

Abudureheman, T., Xia, J., Li, M., Zhou, H., Zheng, W., Zhou, N., Shi, R., Zhu, J., Yang, L., Chen, L., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.663360 · Cited by 18

Estrogen Receptor and the Unfolded Protein Response: Double-Edged Swords in Therapy for Estrogen Receptor-Positive Breast Cancer

Fan, P., & Jordan, V. C. (2022) · Targeted Oncology · doi:10.1007/s11523-022-00870-5 · Cited by 18

Proteins moonlighting in tumor metabolism and epigenetics

Lv, L., & Lei, Q. (2021) · Frontiers of Medicine · doi:10.1007/s11684-020-0818-1 · Cited by 18

Chromosomal Instability as Enabling Feature and Central Hallmark of Breast Cancer

Castellanos, G., Valbuena, D. S., Pérez, E., Villegas, V. E., & Rondón‐Lagos, M. (2023) · Breast Cancer Targets and Therapy · doi:10.2147/bctt.s383759 · Cited by 22

Gene-Specific Intron Retention Serves as Molecular Signature that Distinguishes Melanoma from Non-Melanoma Cancer Cells in Greek Patients

Giannopoulou, A. F., Konstantakou, E. G., Velentzas, A. D., Avgeris, S. N., Avgeris, M., Papandreou, N. C., Zoi, I., Filippa, V., Katarachia, S. A., Lampidonis, A. D., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040937 · Cited by 16

PDGFRβ modulates aerobic glycolysis in osteosarcoma HOS cells via the PI3K/AKT/mTOR/c-Myc pathway

Tang, H., Guo, J., Sang, B., Cheng, J., & Wu, X. (2021) · Biochemistry and Cell Biology · doi:10.1139/bcb-2021-0305 · Cited by 17

Combination of Histone Deacetylase Inhibitor Panobinostat (LBH589) with β-Catenin Inhibitor Tegavivint (BC2059) Exerts Significant Anti-Myeloma Activity Both In Vitro and In Vivo

Savvidou, I., Khong, T. T., Whish, S., Carmichael, I., Sepehrizadeh, T., Mithraprabhu, S., Horrigan, S. K., de Veer, M., & Spencer, A. G. (2022) · Cancers · doi:10.3390/cancers14030840 · Cited by 16

Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway

Fang, Y.-X., Lu, E.-Q., Cheng, Y.-J., Xu, E., Zhu, M., & Chen, X. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c08701 · Cited by 16

Vibrio splendidus infection promotes circRNA-FGL1-regulated coelomocyte apoptosis via competitive binding to Myc with the deubiquitinase OTUB1 in Apostichopus japonicus

Guo, M. Z., Li, X., Tao, W., Teng, F., & Li, C. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012463 · Cited by 16

Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner

Wang, H., Wang, J., Liu, J., Wang, Y., Xia, G., & Huang, X. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110282 · Cited by 16

Prognostic value and potential molecular mechanism of the like-Sm gene family in early-stage pancreatic ductal adenocarcinoma

Chen, Z., Han, C., Zhou, X., Wang, X., Liao, X., He, Y., Mo, S., Li, X., Zhu, G., Ye, X., et al. (2021) · Translational Cancer Research · doi:10.21037/tcr-20-3056 · Cited by 15

MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment

Zormpas‐Petridis, K., Jerome, N. P., Blackledge, M., Carceller, F., Poon, E., Clarke, M., McErlean, C. M., Barone, G., Koers, A., Vaidya, S. J., et al. (2019) · Cancer Research · doi:10.1158/0008-5472.can-18-3412 · Cited by 15

Non-coding RNAs, metabolic stress and adaptive mechanisms in cancer

Liu, X., Feng, S., Zhang, X. D., Li, J., Zhang, K., Wu, M., & Thorne, R. F. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.06.024 · Cited by 15

Differential glutamine metabolism in the tumor microenvironment – studies in diversity and heterogeneity: A mini-review

Claiborne, M. D., & Leone, R. D. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1011191 · Cited by 16

A Functional 5'-UTR Polymorphism of MYC Contributes to Nasopharyngeal Carcinoma Susceptibility and Chemoradiotherapy Induced Toxicities

Guo, Z., Wang, Y., Zhao, Y., Jin, Y., An, L., Xu, H., Liu, Z., Chen, X., Zhou, H., Wang, H., et al. (2018) · Journal of Cancer · doi:10.7150/jca.28534 · Cited by 15

Metabolic Characterization of Antifolate Responsiveness and Non-responsiveness in Malignant Pleural Mesothelioma Cells

Sato, Y., Matsuda, S., Maruyama, A., Nakayama, J., Miyashita, T., Udagawa, H., Umemura, S., Yanagihara, K., Ochiai, A., Tomita, M., et al. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01129 · Cited by 15

PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway

Zhang, W., Zhang, Y., Zhou, W., Qian, F., Hu, M., Chen, Y., Lü, J., Lou, Y., & Han, B. (2021) · Cancer Cell International · doi:10.1186/s12935-020-01714-w · Cited by 13

Glycometabolism and lipid metabolism related genes predict the prognosis of endometrial carcinoma and their effects on tumor cells

Lin, X., Zheng, J., Cai, X., Liu, L., Jiang, S., Liu, Q., & Sun, Y. (2024) · BMC Cancer · doi:10.1186/s12885-024-12327-1 · Cited by 13

Directly Suppressing MYC Function with Novel Alkynyl-Substituted Phenylpyrazole Derivatives that Induce Protein Degradation and Perturb MYC/MAX Interaction

Zhao, C., Zhao, F., Yang, L., Wang, Y., Wang, H., Fang, F., Zuo, H., Li, Z., He, G., Zhan, W., et al. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c00272 · Cited by 13

GATA2 co-opts TGFβ1/SMAD4 oncogenic signaling and inherited variants at 6q22 to modulate prostate cancer progression

Yang, X., Zhang, Q., Li, S., Devarajan, R., Luo, B., Tan, Z., Wang, Z., Giannareas, N., Wenta, T., Ma, W., et al. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02745-7 · Cited by 12

Co-overexpression of RIOK1 and AKT1 as a prognostic risk factor in glioma

Wang, Y., Xie, X., Li, S., Zhang, D., Zheng, H., Zhang, M., & Zhang, Z. (2021) · Journal of Cancer · doi:10.7150/jca.60596 · Cited by 12

Polydatin: A natural compound with multifaceted anticancer properties

Imtiyaz, K., Shafi, M., Fakhri, K. U., Uroog, L., Zeya, B., Anwer, S. T., & Rizvi, M. M. A. (2024) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2024.06.006 · Cited by 15

Protein kinase C iota promotes glycolysis via PI3K/AKT/mTOR signalling in high grade serous ovarian cancer

Tyagi, K., Roy, A., & Mandal, S. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09918-3 · Cited by 12

MYC gene associated polymorphisms and Wilms tumor risk in Chinese children: a four-center case-control study

Liu, J., Hua, R., Fu, W., Zhu, J., Jia, W., Zhang, J., Zhou, H., Cheng, J., Xia, H., Liu, G., et al. (2019) · Annals of Translational Medicine · doi:10.21037/atm.2019.08.31 · Cited by 11

Synergistic Effect of 3-Bromopyruvate in Combination with Rapamycin Impacted Neuroblastoma Metabolism by Inhibiting Autophagy

Gan, L., Ren, Y., Lu, J., Ma, J., Shen, X., & Zhuang, Z. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s273108 · Cited by 12

Knock-down of PGM1 inhibits cell viability, glycolysis, and oxidative phosphorylation in glioma under low glucose condition via the Myc signaling pathway

Liu, S., Deng, Y., Yu, Y., & Xia, X. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.03.034 · Cited by 12

MYCN Amplification Is Associated with Reduced Expression of Genes Encoding γ-Secretase Complex and NOTCH Signaling Components in Neuroblastoma

Agarwal, P., Glowacka, A., Mahmoud, L., Bazzar, W., Larsson, L., & Alzrigat, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098141 · Cited by 12

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

McGuire, T. R., Coulter, D. W., Bai, D., Sughroue, J. A., Li, J., Yang, Z., Qiao, Z., Liu, Y., Murry, D. J., Chhonker, Y. S., et al. (2019) · BMC Cancer · doi:10.1186/s12885-019-6033-2 · Cited by 12

Correlation of Glucose Metabolism with Cancer and Intervention with Traditional Chinese Medicine

Lai, G., Wang, F., Nie, D., Lei, S., Wu, Z., Cao, J., & Tang, L.-L. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/2192654 · Cited by 13

NUAKs promote mTOR/c-Myc-induced glucose and glutamine reprogramming for cell growth and metastasis in breast cancer cells

Raj, A. S. W. W., & Manoharan, R. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167508 · Cited by 11

miR‑20b promotes growth of non‑small cell lung cancer through a positive feedback loop of the Wnt/β‑catenin signaling pathway

Ren, T., Fan, X., Wang, M., Duan, F., Wei, C., Li, R., Jiang, Z., Wang, Y., Yao, X., Chen, M., et al. (2019) · International Journal of Oncology · doi:10.3892/ijo.2019.4940 · Cited by 11

CircREOS suppresses lipid synthesis and osteosarcoma progression through inhibiting HuR-mediated MYC activation

Tong, W., Wang, S., He, C., Li, A., Nie, J., Wei, Z., Yang, F., & Liu, Z. (2023) · Journal of Cancer · doi:10.7150/jca.83106 · Cited by 12

Promoter Hypermethylation of CHODL Contributes to Carcinogenesis and Indicates Poor Survival in Patients with Early-stage Colorectal Cancer

Zhang, X., Wu, K., Huang, Y., Xu, L., Li, X., & Zhang, N. (2020) · Journal of Cancer · doi:10.7150/jca.38815 · Cited by 11

Targeting Oncometabolites in Peritoneal Cancers: Preclinical Insights and Therapeutic Strategies

Nadhan, R., Kashyap, S., Ha, J. H., Jayaraman, M., Song, Y. S., Isidoro, C., & Dhanasekaran, D. N. (2023) · Metabolites · doi:10.3390/metabo13050618 · Cited by 12

Computational modeling of cancer cell metabolism along the catabolic-anabolic axes

Castrejon, J. V., Levine, H., Kaipparettu, B. A., Onuchic, J. N., George, J. T., & Jia, D. (2025) · npj Systems Biology and Applications · doi:10.1038/s41540-025-00525-x · Cited by 10

Altered gene expression in glycolysis–cholesterol synthesis axis correlates with outcome of triple-negative breast cancer

Zhong, P., Shu, R., Wu, H., Liu, Z., Shen, X., & Hu, Y. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220975206 · Cited by 10

Promoting cell proliferation, cell cycle progression, and glycolysis: Glycometabolism‐related genes act as prognostic signatures for prostate cancer

Zhang, Y., Mou, Y., Liang, C., Zhu, S., Liu, S., Shao, P., Li, J., & Wang, Z. (2020) · The Prostate · doi:10.1002/pros.24092 · Cited by 10

Octamer transcription factor-1 induces the Warburg effect via up-regulation of hexokinase 2 in non-small cell lung cancer

Li, Z., Su, J., Sun, M., Song, J., Sun, H., Fan, J., Chen, G., Shan, C., Qi, Q., & Zhang, S. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04171-9 · Cited by 10

Concise review: Cancer cell reprogramming and therapeutic implications

Xiao, X., Chen, H., Yang, L., Xie, G., Shimuzu, R., & Murai, A. (2022) · Translational Oncology · doi:10.1016/j.tranon.2022.101503 · Cited by 10

Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition

Graziani, V., Rodriguez‐Garcia, A., Sainero‐Alcolado, L., Guennec, A. D. L., Arsenian‐Henriksson, M., & Conte, M. R. (2023) · Scientific Reports · doi:10.1038/s41598-023-27375-z · Cited by 10

Unforeseen consequences of synergizing PEGylated rapamycin and quercetin in angiogenesis and metastasis inhibition: Turning failure into benefit

Amili, M. A., Zou, C., Xia, Y., Zeng, P., Qi, Y., Shen, Y., & Guo, S. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.144155 · Cited by 10

TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways

Kong, L., Yu, Y., Guan, H., Jiang, L., Sun, F., Li, X., Huang, W., & Li, B. (2021) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2021.4910 · Cited by 10

Antitumor effects of a covalent cyclin-dependent kinase 7 inhibitor in colorectal cancer

Wang, J., Li, Z., Mei, H., Zhang, D., Wu, G., Zhang, T., & Lin, Z. (2019) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000000749 · Cited by 10

Serinc2 Drives the Progression of Cervical Cancer Through Regulating Myc Pathway

Wang, X., Chen, J., & Li, Q. (2024) · Cancer Medicine · doi:10.1002/cam4.70296 · Cited by 9

Exposure to brominated flame retardants during pregnancy and lactation increases the prevalence of breast lesions and cancer-associated pathways in sprague-dawley rats

McDermott, A., Juárez, M., Wade, M. G., Patten, S. A., & Plante, I. (2025) · Reproductive Toxicology · doi:10.1016/j.reprotox.2025.108928 · Cited by 9

Determination of Breast Metabolic Phenotypes and Their Associations With Immunotherapy and Drug-Targeted Therapy: Analysis of Single-Cell and Bulk Sequences

Bai, M., & Sun, C. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.829029 · Cited by 9

Somatic mtDNA mutation burden shapes metabolic plasticity in leukemogenesis

Li-Harms, X., Lü, J., Fukuda, Y., Lynch, J., Sheth, A., Pareek, G., Kamiński, M. M., Ross, H. S., Wright, C. W., Smith, A. L., et al. (2025) · Science Advances · doi:10.1126/sciadv.ads8489 · Cited by 8

PRPS activity tunes redox homeostasis in Myc-driven lymphoma

MacMillan, A. C., Karki, B., Yang, J., Gertz, K. R., Zumwalde, S., Patel, J. A., Czyzyk-Krzeska, M., Meller, J., & Cunningham, J. T. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103649 · Cited by 8

Enhancers and MYC interplay in hematopoiesis

Benetatos, L., Benetatou, A., & Vartholomatos, G. (2020) · Journal of Molecular Medicine · doi:10.1007/s00109-020-01891-1 · Cited by 8

Asparagine sustains cellular proliferation and c‑Myc expression in glutamine‑starved cancer cells

Chiodi, I., Perini, C., Berardi, D., & Mondello, C. (2021) · Oncology Reports · doi:10.3892/or.2021.8047 · Cited by 8

Metabolic Switch and Cytotoxic Effect of Metformin on Burkitt Lymphoma

Bagaloni, I., Visani, A., Biagiotti, S., Ruzzo, A., Navari, M., Etebari, M., Mundo, L., Granai, M., Lazzi, S., Isidori, A., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.661102 · Cited by 8

Computational insights into the differentiated binding affinities of Myc, Max, and Omomyc dimers to the E-boxes of DNA

Dai, Y., Zhang, J., Wang, Y., Liu, L., & Gao, J. (2022) · Journal of Molecular Modeling · doi:10.1007/s00894-022-05261-1 · Cited by 8

Metformin and glioma: Targeting metabolic dysregulation for enhanced therapeutic outcomes

Basheer, H. A., Salman, N., Abdullah, R. M., Elsalem, L., & Afarinkia, K. (2025) · Translational Oncology · doi:10.1016/j.tranon.2025.102323 · Cited by 7

Clinical Validation of a Noninvasive Multi-Omics Method for Multicancer Early Detection in Retrospective and Prospective Cohorts

Li, S., Geng, S., Chen, Y., Ren, Q., Luan, Y., Liang, W., Chang, Y., Zhang, L., Zhu, D., Wu, W., et al. (2025) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2025.04.001 · Cited by 8

Small interfering RNA (siRNA) based therapies for cancer treatment: A special focus on cervical cancer

Bavishi, L., Butani, S., & Patel, S. S. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.178198 · Cited by 8

miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC

Zhang, X., Sun, J., Zhang, P., Wen, T., Wang, R., Liang, L., Yang, Z., Li, J., Zhang, J., Che, B., et al. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.03.022 · Cited by 7

Role of Notch pathway in effect of mono‐2‐ethylhexyl phthalate on the proliferation and cell cycle of SH‐SY5Y cell

Zhang, B., Li, X., Zhang, X., Ye, J., Zhao, W., Zhang, M., Xing, J., Qi, W., & Ye, L. (2021) · Environmental Toxicology · doi:10.1002/tox.23314 · Cited by 7

Inflammation-Associated Cytotoxic Agents in Tumorigenesis

Arnhold, J. (2023) · Cancers · doi:10.3390/cancers16010081 · Cited by 7

The potential role of glycogen metabolism in diffuse large B-cell lymphoma

Jalali, S., & Ansell, S. M. (2019) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2019.1702185 · Cited by 7

Rocaglamide reprograms glucose metabolism in erythroleukemic cells via c-MYC transcriptional regulation of TXNIP and HK2

SONG, J., Liu, W., Xiao, X., Song, J., Wang, C., Gajendran, B., Wei, X., Yang, C., Chen, Y., Yang, Y., et al. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.119145 · Cited by 6

Synergistic Effect of Ribitol and Shikonin Promotes Apoptosis in Breast Cancer Cells

Doddapaneni, R., Tucker, J. D., Lu, P., & Lu, Q. L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26062661 · Cited by 6

The Role of Non-Coding RNAs in MYC-Mediated Metabolic Regulation: Feedback Loops and Interactions

Alamoudi, A. A. (2025) · Non-Coding RNA · doi:10.3390/ncrna11020027 · Cited by 6

Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia

Zhong, W., Ma, L., Yang, F., Cao, J., Tan, J., & Li, B. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1027441 · Cited by 6

Hyperthermia inhibits growth of nasopharyngeal carcinoma through degradation of c-Myc

Li, X., Duan, S., Zheng, Y., Yang, Y., Wang, L., Li, X., Zhang, Q. H., Thorne, R. F., Li, W., & Yang, D. (2022) · International Journal of Hyperthermia · doi:10.1080/02656736.2022.2038282 · Cited by 6

Regulation of α-Ketoglutarate levels by Myc affects metabolism and demethylation in porcine early embryos

Ding, R., Zhou, Y., Zhang, Q., Kong, X., Li, Q., Zhang, S., Chen, Y., An, X., & Li, Z. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1507102 · Cited by 5

Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

Azevedo-Pouly, A., Hale, M. A., Swift, G. H., Hoàng, C., Deering, T. G., Xue, J., Wilkie, T. M., Murtaugh, L., & MacDonald, R. J. (2023) · PLoS ONE · doi:10.1371/journal.pone.0291512 · Cited by 5

The prognostic roles of CYP19A1 expression in bladder cancer patients of different genders

Cai, S., Feng, Y., Ye, J., Deng, Y., Cai, Z., Zhu, X., Liu, R., Zhang, Y., Zou, Z., Tang, Z., et al. (2021) · Translational Andrology and Urology · doi:10.21037/tau-21-400 · Cited by 4

RAS: Circuitry and therapeutic targeting

Singh, G., Thakur, N., & Kumar, U. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110505 · Cited by 6

Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic ductal adenocarcinoma

Safari, M., Scotto, L., Basseville, A., Litman, T., Xue, H., Petrukhin, L., Zhou, P., Remotti, H. E., Ku, A. W., Morales, D. V., et al. (2025) · Drug Resistance Updates · doi:10.1016/j.drup.2025.101312 · Cited by 5

c-Myc Inhibits Macrophage Antimycobacterial Response in Mycobacterium tuberculosis Infection

Sarti, E., Dollé, C., Wolfensberger, R., Kusejko, K., Russenberger, D., Bredl, S., Speck, R. F., Greter, M., Rueschoff, J. H., Boeck, L., et al. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaf456 · Cited by 4

VRK2 targeting potentiates anti-PD-1 immunotherapy in hepatocellular carcinoma through MYC destabilization

Chen, S., Liao, Z., Mo, J., Liu, F., Wang, W., Zhang, H., Zhang, H., Liu, Y., Pan, Y., Zhu, H., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64079-6 · Cited by 4

ASS1igning purine dependency to cancer

Villa, E., & Ben‐Sahra, I. (2020) · Nature Cancer · doi:10.1038/s43018-020-00117-0 · Cited by 4

Involvement of cardiac glycosides targeting Na/K-ATPase in their inhibitory effects on c-Myc expression via its transcription, translation and proteasomal degradation

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Berberine Targets PKM2 to Activate the t-PA-Induced Fibrinolytic System and Improves Thrombosis

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