Cited by 221Adipokines, Inflammation, and Metabolic DiseasesGestational Diabetes Research and ManagementPregnancy and preeclampsia studies

The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.

Obesity, pregnancy, inflammation, and vascular function

Open access

Abstract

Maternal obesity is associated with increased morbidity and mortality for both mother and offspring. The mechanisms underlying the increased risk associated with maternal obesity are not well understood. In non-pregnant populations, many of the complications of obesity are thought to be mediated in part by inflammation and its sequelae. Recent studies suggest that a heightened inflammatory response may also be involved in mediating adverse clinical outcomes during pregnancy. This review summarizes our current knowledge about adipose tissue biology, and its role as an endocrine and inflammatory organ. The evidence for inflammation as a key mediator of adverse pregnancy outcome is also presented, focusing on the role of inflammation in adipose tissue, systemic inflammation, the placenta, and vascular endothelium.

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Crossref · 10.1530/rep-10-0074

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Research works printed but not linked: 3

  1. Challier, 2008, Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta, Placenta, 29, 274, 10.1016/j.placenta.2007.12.010 · DOI · Paper page
  2. Dorup, 1999, Normal pregnancy is associated with enhanced endothelium-dependent flow-mediated vasodilation, American Journal of Physiology, 276, H821
  3. Gunderson, 2001, Does the pattern of postpartum weight change differ according to pregravid body size?, International Journal of Obesity and Related Metabolic Disorders, 25, 853, 10.1038/sj.ijo.0801631 · DOI

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Items 101–200 of 221

Metadata

Authors
Denison, F. C., Roberts, K. A., Barr, S. M., & Norman, J. E.
Affiliations
The Queen's Medical Research Institute (GB)
Venue
Reproduction
Published
2010-09-01
Volume
140
Issue
3
Pages
373-385
ISSN
  • 1470-1626 (ISSN-L)
  • 1741-7899
OpenAlex
W2116489286
Cited by
221
References
125
Citations by year
2026: 8 · 2025: 9 · 2024: 8 · 2023: 15 · 2022: 12 · 2021: 9 · 2020: 20 · 2019: 16 · 2018: 16 · 2017: 21 · 2016: 12 · 2015: 15 · 2014: 18 · 2013: 18 · 2012: 13
FWCI
9.70
Type
journal article
Language
en
Open access
Locations
  • Reproduction (publishedVersion)
  • PubMed (publishedVersion)
  • Bristol Research (University of Bristol) (submittedVersion)
  • Explore Bristol Research (submittedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
Keywords
maternal obesity, pregnancy complications, inflammation, vascular function, adipose tissue, adipokines, systemic inflammation, placenta, vascular endothelium, adverse pregnancy outcomes, maternal morbidity and mortality
MeSH terms
Adipose Tissue, Endothelium, Vascular, Female, Fibrinolysis, Humans, Inflammation, Obesity, Pregnancy, Pregnancy Complications, Pregnancy Complications, Cardiovascular, Pregnancy Outcome, Risk Factors, Inflammation Mediators

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