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Cited by 348

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Bayesian Clustering Using Hidden Markov Random Fields in Spatial Population Genetics

Open access
François, Olivier, Ancelet, Sophie, Guillot, Gilles·2006·Genetics

Abstract

We introduce a new Bayesian clustering algorithm for studying population structure using individually geo-referenced multilocus data sets. The algorithm is based on the concept of hidden Markov random field, which models the spatial dependencies at the cluster membership level. We argue that (i) a Markov chain Monte Carlo procedure can implement the algorithm efficiently, (ii) it can detect significant geographical discontinuities in allele frequencies and regulate the number of clusters, (iii) it can check whether the clusters obtained without the use of spatial priors are robust to the hypothesis of discontinuous geographical variation in allele frequencies, and (iv) it can reduce the number of loci required to obtain accurate assignments. We illustrate and discuss the implementation issues with the Scandinavian brown bear and the human CEPH diversity panel data set.

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Metadata

Authors
François, O., Ancelet, S., & Guillot, G.
Venue
Genetics
Published
2006-10-01
Volume
174
Issue
2
Pages
805-816
ISSN
  • 0016-6731 (ISSN-L)
  • 1943-2631
OpenAlex
W2113662295
Cited by
348
References
6
FWCI
14.67
Type
journal article
Language
en
Open access
bronze

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