The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Aneuploidy: Cells Losing Their Balance
Open accessAbstract
A change in chromosome number that is not the exact multiple of the haploid karyotype is known as aneuploidy. This condition interferes with growth and development of an organism and is a common characteristic of solid tumors. Here, we review the history of studies on aneuploidy and summarize some of its major characteristics. We will then discuss the molecular basis for the defects caused by aneuploidy and end with speculations as to whether and how aneuploidy, despite its deleterious effects on organismal and cellular fitness, contributes to tumorigenesis.
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Citations
Cites
Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes
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HSP90 and the chaperoning of cancer
Whitesell, L., & Lindquist, S. L. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1716 · Cited by 2,502
Effects of Aneuploidy on Cellular Physiology and Cell Division in Haploid Yeast
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Self-citationChromosome aberrations in solid tumors
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Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae
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Cited by
The causes and consequences of genetic heterogeneity in cancer evolution
Burrell, R. A., McGranahan, N., Bartek, J., & Swanton, C. (2013) · Nature · doi:10.1038/nature12625 · Cited by 2,262
Principles of cancer therapy: oncogene and non-oncogene addiction
Luo, J., Solimini, N. L., & Elledge, S. J. (2009) · Cell · doi:10.1016/j.cell.2009.02.024 · Cited by 1,765
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
Holland, A. J., & Cleveland, D. W. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2718 · Cited by 859
Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
Pavelka, N., Rancati, G., Zhu, J., Bradford, W. D., Saraf, A., Florens, L., Sanderson, B. W., Hattem, G. L., & Li, R. (2010) · Nature · doi:10.1038/nature09529 · Cited by 577
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
Thompson, S. L., & Compton, D. A. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200905057 · Cited by 494
Metadata
- Authors
- Torres, E. M., Williams, B. R., & Amon, A.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-06-01
- Volume
- 179
- Issue
- 2
- Pages
- 737-746
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W2108356291
- Cited by
- 407
- References
- 8
- FWCI
- 9.59
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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